DK481585D0 - Farmaceutisk praeparat indeholdende anthracyclinglycosider - Google Patents

Farmaceutisk praeparat indeholdende anthracyclinglycosider

Info

Publication number
DK481585D0
DK481585D0 DK481585A DK481585A DK481585D0 DK 481585 D0 DK481585 D0 DK 481585D0 DK 481585 A DK481585 A DK 481585A DK 481585 A DK481585 A DK 481585A DK 481585 D0 DK481585 D0 DK 481585D0
Authority
DK
Denmark
Prior art keywords
anthracycling
lycosides
pharmaceutical preparation
preparation containing
pharmaceutical
Prior art date
Application number
DK481585A
Other languages
English (en)
Other versions
DK165620B (da
DK481585A (da
DK165620C (da
Inventor
Gaetano Gatti
Diego Oldani
Carlo Confalonieri
Luciano Gambini
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of DK481585D0 publication Critical patent/DK481585D0/da
Publication of DK481585A publication Critical patent/DK481585A/da
Publication of DK165620B publication Critical patent/DK165620B/da
Application granted granted Critical
Publication of DK165620C publication Critical patent/DK165620C/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK481585A 1984-10-22 1985-10-21 Frysetoerret farmaceutisk praeparat indeholdende anthracyclinglycosider og et cosolubiliserende middel og fremgangsmaade til fremstilling heraf, anvendelse af praeparatet til fremstilling af et tumormiddel samt fremgangsmaade til fremstilling af en rekonstitueret injicerbar oploesning af praeparatet DK165620C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB848426672A GB8426672D0 (en) 1984-10-22 1984-10-22 Pharmaceutical compositions
GB8426672 1984-10-22

Publications (4)

Publication Number Publication Date
DK481585D0 true DK481585D0 (da) 1985-10-21
DK481585A DK481585A (da) 1986-04-23
DK165620B DK165620B (da) 1992-12-28
DK165620C DK165620C (da) 1993-06-01

Family

ID=10568553

Family Applications (1)

Application Number Title Priority Date Filing Date
DK481585A DK165620C (da) 1984-10-22 1985-10-21 Frysetoerret farmaceutisk praeparat indeholdende anthracyclinglycosider og et cosolubiliserende middel og fremgangsmaade til fremstilling heraf, anvendelse af praeparatet til fremstilling af et tumormiddel samt fremgangsmaade til fremstilling af en rekonstitueret injicerbar oploesning af praeparatet

Country Status (35)

Country Link
US (4) US4675311A (da)
JP (1) JPH0611700B2 (da)
KR (1) KR920005813B1 (da)
CN (1) CN85107562B (da)
AT (1) AT401345B (da)
AU (1) AU572003B2 (da)
BE (1) BE903484A (da)
BG (1) BG60934B2 (da)
CA (1) CA1248453A (da)
CH (1) CH667594A5 (da)
CS (1) CS270421B2 (da)
DE (1) DE3536896C2 (da)
DK (1) DK165620C (da)
ES (1) ES8605374A1 (da)
FI (2) FI853913A (da)
FR (1) FR2571966B1 (da)
GB (2) GB8426672D0 (da)
GR (1) GR852549B (da)
HK (1) HK94390A (da)
HU (1) HU197988B (da)
IE (1) IE56992B1 (da)
IL (1) IL76732A (da)
IT (1) IT1186779B (da)
MY (1) MY103956A (da)
NL (1) NL191308C (da)
NO (1) NO170616C (da)
NZ (1) NZ213885A (da)
PH (1) PH23982A (da)
PT (1) PT81347B (da)
RU (2) RU1836088C (da)
SE (1) SE467520B (da)
SG (1) SG80290G (da)
UA (2) UA34419C2 (da)
YU (1) YU46160B (da)
ZA (1) ZA858033B (da)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5124317A (en) * 1985-08-02 1992-06-23 Farmitalia Carlo Erba S.P.A. Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
GB2200047B (en) * 1986-12-05 1990-11-21 Erba Carlo Spa Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
US5124318A (en) * 1985-08-02 1992-06-23 Farmitalia Carlo Erba S.R.L. Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
US5977082A (en) * 1985-08-02 1999-11-02 Pharmacia & Upjohn Company Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
JP2603480B2 (ja) * 1987-08-05 1997-04-23 住友製薬株式会社 安定化されたアンスラサイクリン系製剤
DE3801178A1 (de) * 1988-01-18 1989-07-27 Hoechst Ag Stabilisierte trockenzubereitung zytostatisch wirksamer anthracyclin-antibiotika und verfahren zu ihrer herstellung
US6300361B1 (en) 1990-07-25 2001-10-09 Novartis Ag Stabilized pharmaceutical compositions comprising acid donors
DE69737510T2 (de) 1996-12-30 2007-12-06 Battelle Memorial Institute, Columbus Verwendung eines unverkapselten Antikrebs-Arzneimittels zur Herstellung einer Zubereitung zur Behandlung von Neoplasmen durch Inhalation
US5942508A (en) * 1997-02-04 1999-08-24 Senju Pharmaceutical Co., Ltd. Method for solubilizing pyridonecarboxylic acid solubilizer thereof and aqueous solution containing solubilized pyridonecarboxylic acid
CA2476494C (en) 2002-02-22 2010-04-27 Schering Corporation Pharmaceutical formulations of antineoplastic agents, in particular temozolomide, processes of making and using the same
DK1474995T3 (da) * 2003-05-06 2013-02-18 Gumlink As Fremgangsmåde til fremstilling af tyggegummigranulater, et gummisammensætningsekstruder- og granuleringssystem og et tyggegummiprodukt
US20090099346A1 (en) * 2003-07-02 2009-04-16 Victor Matvienko Thermally stable crystalline epirubicin hydrochloride
ATE520702T1 (de) * 2003-07-02 2011-09-15 Solux Corp Thermisch stabiles kristallines epirubicin- hydrochlorid und herstellungsverfahren dafür
US7314862B2 (en) * 2003-09-25 2008-01-01 Astellas Pharma Inc. Antitumor agent
US7388083B2 (en) * 2005-03-07 2008-06-17 Solux Corporation Epimerization of 4′-C bond and modification of 14-CH3-(CO)-fragment in anthracyclin antibiotics
TW200718426A (en) * 2005-05-11 2007-05-16 Sicor Inc Stable lyophilized anthracycline glycosides
EP2397034A1 (en) 2005-07-14 2011-12-21 Lithera, Inc. Sustained Release Enhanced Lipolytic Formulation for Regional Adipose Tissue Treatment
US9035032B2 (en) * 2005-12-13 2015-05-19 Solux Corporation Method for preparing 4-demethyldaunorubicin
US8802830B2 (en) * 2005-12-20 2014-08-12 Solux Corporation Synthesis of epirubicin from 13-dihydrodaunorubicine
US8148338B2 (en) * 2006-02-22 2012-04-03 Supratek Pharma Inc. Doxorubicin formulations for anti-cancer use
US7470672B2 (en) * 2006-07-31 2008-12-30 Savvipharm Inc. Compositions and methods of reducing tissue levels of drugs when given as orotate derivatives
WO2008138646A1 (en) * 2007-05-16 2008-11-20 Ktb Tumorforschungsgesellschaft Mbh Low-viscous anthracycline formulation
MX2010001263A (es) 2007-09-04 2010-10-04 Meiji Seika Kaisha Inyeccion, solucion de inyeccion y preparacion de equipo de inyeccion.
CA2703149A1 (en) * 2007-10-26 2009-04-30 Pfizer Products Inc. Idarubicin for the treatment of lymphoma in a dog
US8357785B2 (en) * 2008-01-08 2013-01-22 Solux Corporation Method of aralkylation of 4′-hydroxyl group of anthracylins
US9132084B2 (en) 2009-05-27 2015-09-15 Neothetics, Inc. Methods for administration and formulations for the treatment of regional adipose tissue
US20110224176A1 (en) * 2010-01-15 2011-09-15 Lithera, Inc. Lyophilized Cake Formulations
EA201270784A1 (ru) 2010-11-24 2013-04-30 ОБЩЕСТВО С ОГРАНИЧЕННОЙ ОТВЕТСТВЕННОСТЬЮ "НоваМедика" Монотерапевтические композиции селективного липофильного и бета-агониста длительного действия и способы косметического лечения ожирения и контурного выпячивания
DE102011103751A1 (de) 2011-05-31 2012-12-06 Heraeus Precious Metals Gmbh & Co. Kg Kristallisierung von Epirubicinhydrochlorid
DE102011111991A1 (de) * 2011-08-30 2013-02-28 Lead Discovery Center Gmbh Neue Cyclosporin-Derivate
AU2013359048A1 (en) 2012-12-13 2015-07-02 Cytrx Corporation Anthracycline formulations
KR20210059035A (ko) 2013-06-05 2021-05-24 싸이트알엑스 코포레이션 암 치료용 세포독성제

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YU33730B (en) * 1967-04-18 1978-02-28 Farmaceutici Italia Process for preparing a novel antibiotic substance and salts thereof
US4039663A (en) * 1975-03-19 1977-08-02 Societa' Farmaceutici Italia S.P.A. Daunomycins, process for their uses and intermediates
GB1506200A (en) * 1975-04-30 1978-04-05 Farmaceutici Italia Glycosides
GB1567456A (en) * 1976-11-16 1980-05-14 Farmaceutici Italia Daunomycin derivatives
GB2007645B (en) * 1977-10-17 1982-05-12 Stanford Res Inst Int Benzyl anthracyclines and pharmaceutical compositions containing them
US4177264A (en) * 1977-10-17 1979-12-04 Sri International N-benzyl anthracyclines
JPS563851A (en) * 1979-06-22 1981-01-16 Matsushita Electric Works Ltd Fireplace in floor
JPS5756494A (en) * 1980-09-22 1982-04-05 Microbial Chem Res Found New anthracyclin derivative
US4325947A (en) * 1981-05-12 1982-04-20 Farmitalia Carlo Erba S.P.A. 4-Demethoxy-4'-deoxydoxorubicin
IT1210476B (it) * 1981-05-28 1989-09-14 Erba Farmitalia Antracicline.
US4438105A (en) * 1982-04-19 1984-03-20 Farmaitalia Carlo Erba S.P.A 4'-Iododerivatives of anthracycline glycosides
AU554416B2 (en) * 1982-05-24 1986-08-21 Farmitalia Carlo Erba S.P.A. Anthracycline glycosides
US4464529A (en) * 1982-07-20 1984-08-07 Sri International Analogues of morpholinyl daunorubicin and morpholinyl doxorubicin
CA1248944A (en) * 1982-09-28 1989-01-17 Gareth J. Thomas Anthracycline glycosides
JPS5982395A (ja) * 1982-11-02 1984-05-12 Microbial Chem Res Found アントラサイクリン化合物、その製造法およびその用途
GR79729B (da) * 1982-12-20 1984-10-31 Univ Ohio State Res Found
JPS6092212A (ja) * 1983-10-26 1985-05-23 Kyowa Hakko Kogyo Co Ltd ドキソルビシン塩の製剤
US4537882A (en) * 1984-05-10 1985-08-27 Ohio State University 4-Demethoxy-3'-desamino-2'-halo-anthracycline and pharmaceutical composition containing same

Also Published As

Publication number Publication date
US4675311A (en) 1987-06-23
NL191308C (nl) 1995-05-16
BG60934B2 (bg) 1996-06-28
IE852593L (en) 1986-04-22
DK165620B (da) 1992-12-28
NL8502869A (nl) 1986-05-16
YU164485A (en) 1987-10-31
CN85107562B (zh) 1988-06-01
FR2571966B1 (fr) 1988-04-15
CS756585A2 (en) 1989-11-14
FR2571966A1 (fr) 1986-04-25
HU197988B (en) 1989-07-28
JPH0611700B2 (ja) 1994-02-16
FI854035L (fi) 1986-04-23
KR860003014A (ko) 1986-05-19
CN85107562A (zh) 1986-07-23
HUT40759A (en) 1987-02-27
FI854035A0 (fi) 1985-10-16
BE903484A (fr) 1986-04-21
US5091372A (en) 1992-02-25
GB2165751B (en) 1988-08-17
ES547578A0 (es) 1986-03-16
US5091373A (en) 1992-02-25
YU46160B (sh) 1993-05-28
FI853913A0 (fi) 1985-10-08
RU2101018C1 (ru) 1998-01-10
PT81347B (pt) 1987-11-11
SE467520B (sv) 1992-08-03
FI86252B (fi) 1992-04-30
MY103956A (en) 1993-10-30
NO170616B (no) 1992-08-03
PH23982A (en) 1990-02-09
IT8522507A0 (it) 1985-10-16
IL76732A (en) 1989-07-31
DE3536896A1 (de) 1986-04-24
AU4880585A (en) 1986-05-01
KR920005813B1 (ko) 1992-07-20
CS270421B2 (en) 1990-06-13
IT1186779B (it) 1987-12-16
UA34419C2 (uk) 2001-03-15
SE8504945L (sv) 1986-04-23
SE8504945D0 (sv) 1985-10-21
NZ213885A (en) 1988-05-30
JPS61246129A (ja) 1986-11-01
GB8525709D0 (en) 1985-11-20
GB8426672D0 (en) 1984-11-28
US4840938A (en) 1989-06-20
DE3536896C2 (de) 1996-11-14
ZA858033B (en) 1986-06-25
ATA303285A (de) 1996-01-15
SG80290G (en) 1990-11-23
CA1248453A (en) 1989-01-10
RU1836088C (ru) 1993-08-23
AU572003B2 (en) 1988-04-28
UA19169A (uk) 1997-12-25
GR852549B (da) 1986-02-24
DK481585A (da) 1986-04-23
HK94390A (en) 1990-11-23
IL76732A0 (en) 1986-02-28
GB2165751A (en) 1986-04-23
DK165620C (da) 1993-06-01
NO854194L (no) 1986-04-23
FI86252C (fi) 1992-08-10
PT81347A (en) 1985-11-01
IE56992B1 (en) 1992-02-26
AT401345B (de) 1996-08-26
CH667594A5 (de) 1988-10-31
NL191308B (nl) 1994-12-16
ES8605374A1 (es) 1986-03-16
FI853913A (fi) 1986-04-23
NO170616C (no) 1992-11-11

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