DK400884A - Tautomere trans-(+-)-alkylerede octahydropyrazolo(3,4-g)- og -(4,3-f)-quinoliner, fremgangsmaade til fremstilling heraf og mellemprodukt til brug ved fremgangsmaaden - Google Patents
Tautomere trans-(+-)-alkylerede octahydropyrazolo(3,4-g)- og -(4,3-f)-quinoliner, fremgangsmaade til fremstilling heraf og mellemprodukt til brug ved fremgangsmaaden Download PDFInfo
- Publication number
- DK400884A DK400884A DK400884A DK400884A DK400884A DK 400884 A DK400884 A DK 400884A DK 400884 A DK400884 A DK 400884A DK 400884 A DK400884 A DK 400884A DK 400884 A DK400884 A DK 400884A
- Authority
- DK
- Denmark
- Prior art keywords
- octahydropyrazolo
- quinolines
- tautomer
- alkylated
- intermediates
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/10—Spiro-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US53551983A | 1983-09-26 | 1983-09-26 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK400884D0 DK400884D0 (da) | 1984-08-22 |
| DK400884A true DK400884A (da) | 1985-03-27 |
Family
ID=24134591
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK400884A DK400884A (da) | 1983-09-26 | 1984-08-22 | Tautomere trans-(+-)-alkylerede octahydropyrazolo(3,4-g)- og -(4,3-f)-quinoliner, fremgangsmaade til fremstilling heraf og mellemprodukt til brug ved fremgangsmaaden |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP0145121B1 (de) |
| JP (4) | JPS6110583A (de) |
| KR (1) | KR870001159B1 (de) |
| CA (1) | CA1270488A (de) |
| DE (1) | DE3484925D1 (de) |
| DK (1) | DK400884A (de) |
| GB (1) | GB2146984B (de) |
| GR (1) | GR80200B (de) |
| HU (1) | HU199836B (de) |
| IL (1) | IL72729A (de) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6392722A (ja) * | 1986-10-03 | 1988-04-23 | Unitika Ltd | 熱接着繊維およびその不織布 |
| JPS6392723A (ja) * | 1986-10-06 | 1988-04-23 | Unitika Ltd | 湿潤性複合繊維およびその不織布 |
| JPS6420322A (en) * | 1987-07-13 | 1989-01-24 | Mitsubishi Petrochemical Co | Conjugated fiber |
| JPH01204617A (ja) * | 1988-02-09 | 1989-08-17 | Chisso Corp | 敷物 |
| GB8828669D0 (en) * | 1988-12-08 | 1989-01-11 | Lilly Industries Ltd | Organic compounds |
| KR20000008130A (ko) * | 1998-07-10 | 2000-02-07 | 조정래 | 폴리에스터계 탄성사용 공중합물의 제조방법 |
| EP2661175A4 (de) | 2011-01-07 | 2013-12-04 | Corcept Therapeutics Inc | Kombinationssteroid- und glucocorticoid-rezeptorantagonistentherapie |
| US20130225633A1 (en) * | 2012-02-27 | 2013-08-29 | Corcept Therapeutics, Inc. | Phenyl heterocycloalkyl glucocorticoid receptor modulators |
| US8859774B2 (en) | 2012-05-25 | 2014-10-14 | Corcept Therapeutics, Inc. | Heteroaryl-ketone fused azadecalin glucocorticoid receptor modulators |
| FI3848027T3 (fi) | 2013-11-25 | 2023-05-04 | Corcept Therapeutics Inc | Oktahydrofuusioituja atsadekaliiniglukokortikoidireseptorin modulaattoreita |
| UA127409C2 (uk) | 2017-03-31 | 2023-08-16 | Корцепт Терап'Ютікс, Інк. | Модулятори глюкокортикоїдного рецептора для лікування раку шийки матки |
| JP7218438B2 (ja) | 2018-12-19 | 2023-02-06 | コーセプト セラピューティクス， インコーポレイテッド | レラコリラント含有医薬製剤、ヘテロアリールケトン縮合アザデカリン化合物 |
| US11389432B2 (en) | 2018-12-19 | 2022-07-19 | Corcept Therapeutics Incorporated | Methods of treating cancer comprising administration of a glucocorticoid receptor modulator and a cancer chemotherapy agent |
| US11234971B2 (en) | 2018-12-19 | 2022-02-01 | Corcept Therapeutics Incorporated | Methods of treating cancer comprising administration of a glucocorticoid receptor modulator and a cancer chemotherapy agent |
| EP3927345A4 (de) | 2019-02-22 | 2022-12-21 | Corcept Therapeutics Incorporated | Therapeutische verwendung von relacorilant, einem heteroaryl-keton-fusionierten azadecalin-glucocorticoid-rezeptor-modulator |
| US11903945B2 (en) | 2019-12-11 | 2024-02-20 | Corcept Therapeutics Incorporated | Methods of treating antipsychotic-induced weight gain with miricorilant |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4230861A (en) * | 1979-01-22 | 1980-10-28 | Eli Lilly And Company | 1-And/or 7-substituted-6-hydroxy (or oxo)-3-decahydroquinoline carboxylic acids |
| US4198415A (en) * | 1979-01-22 | 1980-04-15 | Eli Lilly And Company | Prolactin inhibiting octahydro pyrazolo[3,4-g]quinolines |
| SU776048A1 (ru) * | 1979-06-05 | 1983-09-23 | Институт Бисорганической Химии Ан Бсср | Производные 8-аза-16-оксагона-17-онов, про вл ющие противовоспалительную,мембраностабилизирующую и антифибринолитическую активность,и способ их получени |
| US4252945A (en) * | 1979-07-11 | 1981-02-24 | E. R. Squibb & Sons, Inc. | Process for preparing pyrazolo[1,5-c]-quinazoline derivatives and novel intermediates |
| US4367231A (en) * | 1979-09-14 | 1983-01-04 | Eli Lilly And Company | Method of using octahydro pyrazolo[3,4-g]quinolines |
| ES8504174A1 (es) * | 1982-11-03 | 1985-04-16 | Lilly Co Eli | Un procedimiento para la preparacion de derivados de pirazolo-quinolinas. |
-
1984
- 1984-08-20 IL IL72729A patent/IL72729A/xx unknown
- 1984-08-20 CA CA000461330A patent/CA1270488A/en not_active Expired - Lifetime
- 1984-08-21 DE DE8484305685T patent/DE3484925D1/de not_active Expired - Lifetime
- 1984-08-21 EP EP84305685A patent/EP0145121B1/de not_active Expired - Lifetime
- 1984-08-21 GB GB08421159A patent/GB2146984B/en not_active Expired
- 1984-08-22 HU HU843161A patent/HU199836B/hu not_active IP Right Cessation
- 1984-08-22 DK DK400884A patent/DK400884A/da not_active Application Discontinuation
- 1984-08-23 GR GR80200A patent/GR80200B/el unknown
- 1984-08-24 KR KR1019840005148A patent/KR870001159B1/ko not_active IP Right Cessation
- 1984-08-24 JP JP59177382A patent/JPS6110583A/ja active Granted
-
1992
- 1992-09-16 JP JP4246442A patent/JPH0625251A/ja active Pending
- 1992-09-16 JP JP4246412A patent/JPH05194511A/ja active Pending
- 1992-09-16 JP JP4246440A patent/JPH0660183B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| GR80200B (en) | 1985-01-02 |
| GB8421159D0 (en) | 1984-09-26 |
| JPH0660183B2 (ja) | 1994-08-10 |
| JPS6110583A (ja) | 1986-01-18 |
| JPH05194527A (ja) | 1993-08-03 |
| DE3484925D1 (de) | 1991-09-19 |
| DK400884D0 (da) | 1984-08-22 |
| KR870001159B1 (ko) | 1987-06-13 |
| JPH0625251A (ja) | 1994-02-01 |
| IL72729A0 (en) | 1984-11-30 |
| JPH0568475B2 (de) | 1993-09-29 |
| EP0145121B1 (de) | 1991-08-14 |
| KR850002480A (ko) | 1985-05-13 |
| HUT34750A (en) | 1985-04-28 |
| CA1270488A (en) | 1990-06-19 |
| EP0145121A2 (de) | 1985-06-19 |
| HU199836B (en) | 1990-03-28 |
| EP0145121A3 (en) | 1988-04-27 |
| IL72729A (en) | 1988-02-29 |
| JPH05194511A (ja) | 1993-08-03 |
| GB2146984A (en) | 1985-05-01 |
| GB2146984B (en) | 1987-04-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ATS | Application withdrawn |