FR2554444B1 - 1,25-dihydroxyvitamines d2 et procedes pour les preparer - Google Patents

1,25-dihydroxyvitamines d2 et procedes pour les preparer

Info

Publication number
FR2554444B1
FR2554444B1 FR8416894A FR8416894A FR2554444B1 FR 2554444 B1 FR2554444 B1 FR 2554444B1 FR 8416894 A FR8416894 A FR 8416894A FR 8416894 A FR8416894 A FR 8416894A FR 2554444 B1 FR2554444 B1 FR 2554444B1
Authority
FR
France
Prior art keywords
dihydroxyvitamins
preparing
processes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8416894A
Other languages
English (en)
Other versions
FR2554444A1 (fr
Inventor
Hector F Deluca
Heinrich K Schnoes
Rafal R Sicinski
Yoko Tanaka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wisconsin Alumni Research Foundation
Original Assignee
Wisconsin Alumni Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Research Foundation filed Critical Wisconsin Alumni Research Foundation
Publication of FR2554444A1 publication Critical patent/FR2554444A1/fr
Application granted granted Critical
Publication of FR2554444B1 publication Critical patent/FR2554444B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0036—Nitrogen-containing hetero ring
    • C07J71/0042—Nitrogen only

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR8416894A 1983-11-07 1984-11-06 1,25-dihydroxyvitamines d2 et procedes pour les preparer Expired FR2554444B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/549,047 US4769181A (en) 1983-11-07 1983-11-07 1,25-dihydroxyvitamin D2 compounds

Publications (2)

Publication Number Publication Date
FR2554444A1 FR2554444A1 (fr) 1985-05-10
FR2554444B1 true FR2554444B1 (fr) 1987-11-06

Family

ID=24191451

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8416894A Expired FR2554444B1 (fr) 1983-11-07 1984-11-06 1,25-dihydroxyvitamines d2 et procedes pour les preparer

Country Status (6)

Country Link
US (1) US4769181A (fr)
AU (1) AU3390284A (fr)
BE (1) BE900979A (fr)
FR (1) FR2554444B1 (fr)
GB (1) GB2149408A (fr)
WO (1) WO1985002189A1 (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2608322B2 (ja) * 1988-04-11 1997-05-07 日清製粉株式会社 １α，２５‐ジヒドロキシビタミンＤ▲下２▼類の製造法
US4973584A (en) * 1989-03-09 1990-11-27 Deluca Hector F Novel 1α-hydroxyvitamin D2 epimer and derivatives
CA1333616C (fr) * 1989-03-09 1994-12-20 Hector F. Deluca Composes de type 19-nor-vitamine d
US5246925A (en) * 1989-03-09 1993-09-21 Wisconsin Alumni Research Foundation 19-nor-vitamin D compounds for use in treating hyperparathyroidism
JP2645130B2 (ja) * 1989-03-31 1997-08-25 日清製粉株式会社 ステロイド誘導体
US5260290A (en) * 1990-02-14 1993-11-09 Wisconsin Alumni Research Foundation Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives
US5030772A (en) * 1990-02-14 1991-07-09 Deluca Hector F Process for preparing vitamin D2 compounds and the corresponding 1 α-hydroxylated derivatives
IN171449B (fr) * 1990-02-14 1992-10-17 Wisconsin Alumni Res Found
US5756783A (en) * 1990-09-21 1998-05-26 Bone Care International, Inc. 1α-Hydroxy-24-EPI-vitamin D4
AU656829B2 (en) * 1991-12-26 1995-02-16 Wisconsin Alumni Research Foundation 26, 27-dimethylene-1 alpha, 25-dihydroxyvitamin D2 and 26,27-dihydroxyvitamin D2 and methods for preparing same
EP0631500B1 (fr) * 1992-01-29 1998-04-22 Bone Care International, Inc. 1 alpha-HYDROXY-24-(EPI)-VITAMINE D4
US5194431A (en) * 1992-07-08 1993-03-16 Wisconsin Alumni Research Foundation 24-cyclopropane vitamin D derivatives
US5565589A (en) * 1993-11-03 1996-10-15 Wisconsin Alumni Research Foundation 17-formyl-5,6-trans-vitamin D compounds
US5373004A (en) * 1993-11-24 1994-12-13 Wisconsin Alumni Research Foundation 26,28-methylene-1α, 25-dihydroxyvitamin D2 compounds
DE69503394T2 (de) * 1994-01-20 1999-03-11 Duphar Int Res Vitamin-D-Derivate und Verfahren zu deren Herstellung
US5716946A (en) * 1996-02-13 1998-02-10 Wisconsin Alumni Research Foundation Multiple sclerosis treatment
US6479474B2 (en) * 1999-07-08 2002-11-12 Wisconsin Alumni Research Foundation Dietary calcium as a supplement to vitamin D compound treatment of multiple sclerosis
JP5009617B2 (ja) * 2003-08-20 2012-08-22 ウイスコンシン アラムニ リサーチ ファンデーション ２−メチレン−１９−ノル−ビタミンｄ２化合物
JP5932339B2 (ja) 2009-01-27 2016-06-08 バーグ エルエルシー 化学療法に付随する副作用を軽減するためのビタミンｄ３およびその類似体
IN2012DN02137A (fr) 2009-08-14 2015-08-07 Berg Biosystems Llc
SG10201709894RA (en) 2013-05-29 2018-01-30 Berg Llc Preventing or mitigating chemotherapy induced alopecia using vitamin d

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3880894A (en) * 1974-05-24 1975-04-29 Wisconsin Alumni Res Found 1,25-Dihydroxyergocalciferol
US4260549A (en) * 1979-05-21 1981-04-07 Wisconsin Alumni Research Foundation Process for preparing 1α-hydroxylated compounds
US4225596A (en) * 1978-10-13 1980-09-30 Wisconsin Alumni Research Foundation Method for treating calcium imbalance and improving calcium absorption in mammals
FR2457282A1 (fr) * 1979-05-23 1980-12-19 Roussel Uclaf Nouveau derive du 1a,25 dihydroxy cholecalciferol, son procede de preparation et son application comme medicament
US4265822A (en) * 1979-09-10 1981-05-05 Wisconsin Alumni Research Foundation Process for preparing 1-hydroxylated vitamin D compounds from 5,6-trans-vitamin D compounds
US4338250A (en) * 1981-04-27 1982-07-06 Wisconsin Alumni Research Foundation 1-Hydroxylation process
BE899612A (fr) * 1983-05-09 1984-08-31 Wisconsin Alumni Res Found Derives 1 alpha, 25-dihydroxiles de la vitamine d2 et produits intermediaires pour leur preparation et compositions pharmaceutiques renfermant ces derives.

Also Published As

Publication number Publication date
GB8428031D0 (en) 1984-12-12
GB2149408A (en) 1985-06-12
US4769181A (en) 1988-09-06
WO1985002189A1 (fr) 1985-05-23
FR2554444A1 (fr) 1985-05-10
AU3390284A (en) 1985-06-03
BE900979A (fr) 1985-03-01

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Legal Events

Date Code Title Description
ST Notification of lapse