DK37290D0 - Humant immunsystem i ikke-humane dyr - Google Patents

Humant immunsystem i ikke-humane dyr

Info

Publication number
DK37290D0
DK37290D0 DK037290A DK37290A DK37290D0 DK 37290 D0 DK37290 D0 DK 37290D0 DK 037290 A DK037290 A DK 037290A DK 37290 A DK37290 A DK 37290A DK 37290 D0 DK37290 D0 DK 37290D0
Authority
DK
Denmark
Prior art keywords
human
donor
immune system
recipient
animals
Prior art date
Application number
DK037290A
Other languages
Danish (da)
English (en)
Other versions
DK37290A (da
Inventor
Donald E Mosier
Darcy B Wilson
Original Assignee
Medical Biology Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medical Biology Inst filed Critical Medical Biology Inst
Publication of DK37290A publication Critical patent/DK37290A/da
Publication of DK37290D0 publication Critical patent/DK37290D0/da

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0271—Chimeric vertebrates, e.g. comprising exogenous cells

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Environmental Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Animal Husbandry (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Eye Examination Apparatus (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
DK037290A 1988-06-14 1990-02-13 Humant immunsystem i ikke-humane dyr DK37290D0 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US20727388A 1988-06-14 1988-06-14
US24159088A 1988-09-08 1988-09-08
PCT/US1989/002591 WO1989012823A1 (en) 1988-06-14 1989-06-14 Human immune system in non-human animal

Publications (2)

Publication Number Publication Date
DK37290A DK37290A (da) 1990-02-13
DK37290D0 true DK37290D0 (da) 1990-02-13

Family

ID=26902105

Family Applications (1)

Application Number Title Priority Date Filing Date
DK037290A DK37290D0 (da) 1988-06-14 1990-02-13 Humant immunsystem i ikke-humane dyr

Country Status (9)

Country Link
EP (1) EP0379554B1 (fi)
JP (2) JP2981486B2 (fi)
KR (1) KR900702367A (fi)
AT (1) ATE138195T1 (fi)
AU (1) AU626560B2 (fi)
DE (1) DE68926497T2 (fi)
DK (1) DK37290D0 (fi)
FI (1) FI900708A0 (fi)
WO (1) WO1989012823A1 (fi)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5849288A (en) * 1990-01-15 1998-12-15 Yeda Research And Development Co. Ltd. Method for production of monoclonal antibodies in chimeric mice or rats having xenogeneic antibody-producing cells
US5652373A (en) * 1990-01-15 1997-07-29 Yeda Research And Development Co. Ltd. Engraftment and development of xenogeneic cells in normal mammals having reconstituted hematopoetic deficient immune systems
US5147784A (en) * 1990-04-12 1992-09-15 Systemix, Inc. T-lymphocyte progenitor cell assay
ATE140480T1 (de) * 1990-05-03 1996-08-15 Systemix Inc Menschliches lymph-gewebe in einem wirt mit angegriffenem immunsystem
CA2064075A1 (en) * 1990-05-25 1991-11-26 Charles M. Baum Human peripheral blood cells in an immunocompromised host
DK9091D0 (da) * 1991-01-18 1991-01-18 Novo Nordisk As Fremgangsmaade til fremstilling af antistoffer
US5858328A (en) * 1991-06-04 1999-01-12 Yeda Research And Development Co. Ltd. Animal model for hepatitis virus infection
US5804160A (en) * 1991-06-04 1998-09-08 Yeda Research And Development Co. Ltd Animal model for hepatitis virus infection
US5849987A (en) * 1992-06-02 1998-12-15 Yeda Research And Development Co. Ltd. Animal model for hepatitis virus infection
GB9119338D0 (en) 1991-09-10 1991-10-23 Inst Of Animal Physiology And Control of gene expression
US5866757A (en) * 1992-06-02 1999-02-02 Yeda Research And Development Co. Ltd. Engraftment and development of xenogeneic cells in normal mammals having reconstituted hematopoetic deficient immune systems
US5663481A (en) * 1993-08-06 1997-09-02 Mount Sinai Hospital Corporation Animal model of the human immune system
US6203787B1 (en) 1997-10-10 2001-03-20 The Regents Of The University Of California Treating tumors using implants comprising combinations of allogeneic cells
US7361332B2 (en) 1995-03-17 2008-04-22 The Regents Of The University Of California Treating tumors using implants comprising combinations of allogeneic cells
JP4312265B2 (ja) * 1997-04-09 2009-08-12 ラング−ジ チャン ワクチン評価のための動物モデル
US7175839B1 (en) 1997-10-10 2007-02-13 Meyer Pharmaceuticals Llc Cancer immunotherapy using allostimulated cells in a multiple sequential implantation strategy
US7651855B2 (en) 2003-04-17 2010-01-26 The Trustees Of The University Of Pennsylvania Regulatory T cells and their use in immunotherapy and suppression of autoimmune responses
WO2005056052A1 (en) * 2003-11-14 2005-06-23 Avanir Pharmaceuticals Neutralizing human antibodies to anthrax toxin generated by recall technology
EP2098536A1 (en) 2008-03-05 2009-09-09 4-Antibody AG Isolation and identification of antigen- or ligand-specific binding proteins
EP3056082B1 (en) 2009-10-06 2018-09-05 Regeneron Pharmaceuticals, Inc. Genetically modified mice and engraftment
KR102109172B1 (ko) 2011-02-15 2020-05-12 리제너론 파마슈티칼스 인코포레이티드 인간화된 ｍ－ｃｓｆ 마우스
CA2881468C (en) 2012-09-07 2023-03-21 Yale University Genetically modified mice which express human cytokines and methods of use thereof, including engraftment
AU2013337242B2 (en) 2012-11-05 2019-04-04 Institute For Research In Biomedicine (Irb) Genetically modified non-human animals and methods of use thereof
DK3841877T3 (da) 2014-05-19 2023-11-27 Regeneron Pharma Genetisk modificeret mus, der eksprimerer human EPO
KR20240060648A (ko) 2015-04-13 2024-05-08 리제너론 파마슈티칼스 인코포레이티드 인간화된 sirpa-il15 녹인 마우스 및 이의 이용 방법
CN111149767B (zh) * 2020-02-24 2021-07-20 中南大学湘雅二医院 一种人源化皮肤型红斑狼疮小鼠模型的构建方法和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5823973A (ja) * 1981-08-05 1983-02-12 三菱レイヨン株式会社 耐汚染性、耐黄変性壁紙
JPS6030656B2 (ja) * 1982-01-26 1985-07-17 株式会社林原生物化学研究所 ヒトｔ細胞増殖因子の製造方法
AU7873187A (en) * 1986-08-08 1988-02-24 University Of Minnesota Method of culturing leukocytes
ES2071620T3 (es) * 1987-12-23 1995-07-01 Univ Leland Stanford Junior Mamiferos inmunodeficientes quimericos y su utilizacion.
GR1001034B (el) * 1989-07-21 1993-03-31 Ortho Pharma Corp Μεθοδος διεγερσης του πολλαπλασιασμου λεμφοκυτταρων περιφερειακου αιματος.

Also Published As

Publication number Publication date
JP2960452B2 (ja) 1999-10-06
EP0379554A4 (en) 1992-05-27
DE68926497D1 (de) 1996-06-20
AU626560B2 (en) 1992-08-06
EP0379554A1 (en) 1990-08-01
KR900702367A (ko) 1990-12-06
JPH02502697A (ja) 1990-08-30
DK37290A (da) 1990-02-13
JP2981486B2 (ja) 1999-11-22
WO1989012823A1 (en) 1989-12-28
DE68926497T2 (de) 1996-09-19
JPH0213336A (ja) 1990-01-17
ATE138195T1 (de) 1996-06-15
FI900708A0 (fi) 1990-02-13
EP0379554B1 (en) 1996-05-15
AU3852689A (en) 1990-01-12

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