DK3702443T3 - Sammensætninger og fremgangsmåder til opformering og dyrkning af epiteliale stamceller - Google Patents

Sammensætninger og fremgangsmåder til opformering og dyrkning af epiteliale stamceller Download PDF

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Publication number
DK3702443T3
DK3702443T3 DK20156482.0T DK20156482T DK3702443T3 DK 3702443 T3 DK3702443 T3 DK 3702443T3 DK 20156482 T DK20156482 T DK 20156482T DK 3702443 T3 DK3702443 T3 DK 3702443T3
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epitelial
cultivation
compositions
production
methods
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DK20156482.0T
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Danish (da)
English (en)
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Xiaolei Yin
Marc David Succi
Robert Samuel Langer
Jeffrey Michael Karp
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Brigham & Womens Hospital Inc
Massachusetts Inst Technology
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    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
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    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0679—Cells of the gastro-intestinal tract
    • C12N5/068—Stem cells; Progenitors
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/065—Modulators of histone acetylation
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/155—Bone morphogenic proteins [BMP]; Osteogenins; Osteogenic factor; Bone inducing factor
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/40—Regulators of development
    • C12N2501/42—Notch; Delta; Jagged; Serrate
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/70—Enzymes
    • C12N2501/72—Transferases [EC 2.]
    • C12N2501/727—Kinases (EC 2.7.)
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/70—Enzymes
    • C12N2501/73—Hydrolases (EC 3.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2513/00—3D culture

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  • Health & Medical Sciences (AREA)
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  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
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  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
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  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Developmental Biology & Embryology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
DK20156482.0T 2013-03-14 2014-03-11 Sammensætninger og fremgangsmåder til opformering og dyrkning af epiteliale stamceller DK3702443T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361783245P 2013-03-14 2013-03-14
EP14774723.2A EP2970890B1 (en) 2013-03-14 2014-03-11 Compositions and methods for epithelial stem cell expansion and culture

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DK3702443T3 true DK3702443T3 (da) 2022-04-04

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DK20156482.0T DK3702443T3 (da) 2013-03-14 2014-03-11 Sammensætninger og fremgangsmåder til opformering og dyrkning af epiteliale stamceller
DK14774723.2T DK2970890T3 (da) 2013-03-14 2014-03-11 Sammensætninger og fremgangsmåder til opformering og dyrkning af epitelstamceller

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US (4) US10041046B2 (enExample)
EP (3) EP2970890B1 (enExample)
JP (3) JP6469643B2 (enExample)
KR (1) KR102168088B1 (enExample)
CN (2) CN105358677B (enExample)
AU (1) AU2014240603B2 (enExample)
BR (1) BR112015023261A2 (enExample)
CA (2) CA3184040A1 (enExample)
CY (1) CY1122934T1 (enExample)
DK (2) DK3702443T3 (enExample)
ES (2) ES2786925T3 (enExample)
HR (1) HRP20200692T1 (enExample)
HU (2) HUE057521T2 (enExample)
IL (1) IL241572B (enExample)
LT (1) LT2970890T (enExample)
NZ (1) NZ713219A (enExample)
PL (2) PL2970890T3 (enExample)
PT (2) PT3702443T (enExample)
RS (1) RS60371B1 (enExample)
SI (1) SI2970890T1 (enExample)
SM (1) SMT202000223T1 (enExample)
WO (1) WO2014159356A1 (enExample)
ZA (1) ZA201904258B (enExample)

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