DK369086D0 - Indenanaloge af mevalonolacton og derivater deraf - Google Patents

Indenanaloge af mevalonolacton og derivater deraf

Info

Publication number
DK369086D0
DK369086D0 DK369086A DK369086A DK369086D0 DK 369086 D0 DK369086 D0 DK 369086D0 DK 369086 A DK369086 A DK 369086A DK 369086 A DK369086 A DK 369086A DK 369086 D0 DK369086 D0 DK 369086D0
Authority
DK
Denmark
Prior art keywords
6alkyl
hydrogen
3alkyl
benzyloxy
phenoxy
Prior art date
Application number
DK369086A
Other languages
Danish (da)
English (en)
Other versions
DK369086A (da
Inventor
Faizulla G Kathawala
Sompong Wattanasin
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of DK369086A publication Critical patent/DK369086A/da
Publication of DK369086D0 publication Critical patent/DK369086D0/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/738—Esters of keto-carboxylic acids or aldehydo-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/30—Oxygen atoms, e.g. delta-lactones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/26—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton
    • C07C17/263—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by condensation reactions
    • C07C17/2632—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by condensation reactions involving an organo-magnesium compound, e.g. Grignard synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/20—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
    • C07C47/24—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
    • C07C47/56—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing hydroxy groups
    • C07C47/57—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing hydroxy groups polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/90—Unsaturated compounds containing keto groups containing singly bound oxygen-containing groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/732—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids of unsaturated hydroxy carboxylic acids
DK369086A 1984-12-04 1986-08-01 Indenanaloge af mevalonolacton og derivater deraf DK369086D0 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US67791784A 1984-12-04 1984-12-04
PCT/EP1985/000653 WO1986003488A1 (en) 1984-12-04 1985-11-29 Indene analogs of mevalonolactone and derivatives thereof

Publications (2)

Publication Number Publication Date
DK369086A DK369086A (da) 1986-08-01
DK369086D0 true DK369086D0 (da) 1986-08-01

Family

ID=24720627

Family Applications (1)

Application Number Title Priority Date Filing Date
DK369086A DK369086D0 (da) 1984-12-04 1986-08-01 Indenanaloge af mevalonolacton og derivater deraf

Country Status (19)

Country Link
EP (1) EP0216785B1 (xx)
JP (1) JPS62501009A (xx)
KR (1) KR910003427B1 (xx)
AT (1) ATE60571T1 (xx)
AU (1) AU599580B2 (xx)
DE (1) DE3581638D1 (xx)
DK (1) DK369086D0 (xx)
ES (1) ES8800888A1 (xx)
FI (1) FI863121A0 (xx)
GR (1) GR852895B (xx)
HU (1) HU198005B (xx)
IL (1) IL77199A (xx)
MY (1) MY100972A (xx)
NZ (1) NZ214402A (xx)
PH (1) PH24502A (xx)
PL (1) PL147645B1 (xx)
PT (1) PT81603B (xx)
WO (1) WO1986003488A1 (xx)
ZA (1) ZA859303B (xx)

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US4904691A (en) * 1987-12-21 1990-02-27 Rorer Pharmaceutical Corporation Novel HMG-CoA reductase inhibitors
US4822799A (en) * 1988-01-27 1989-04-18 Sandoz Pharm. Corp. Pyrazolopyridine analogs of mevalonolactone and derivatives thereof useful for inhibiting cholesterol biosynthesis in mammals
US4876280A (en) * 1988-03-10 1989-10-24 Sandoz Pharm. Corp. Arylcyclohexane and arylcyclohexene analogs of mevalonolactone derivatives and their use
US5506219A (en) * 1988-08-29 1996-04-09 E. R. Squibb & Sons, Inc. Pyridine anchors for HMG-CoA reductase inhibitors
ES2060712T3 (es) * 1988-10-13 1994-12-01 Sandoz Ag Proceso para la preparacion de acidos 7-sustituido-hept-6-enoicos y -heptanoicos y derivados y compuestos intermedios de los mismos.
FR2642065B1 (fr) * 1989-01-24 1991-05-24 Lipha Derives d'acides benzocycloalcenyl dihydroxy alcanoiques, procede de preparation et medicaments les contenant
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US5189180A (en) * 1989-09-28 1993-02-23 E. R. Squibb & Sons, Inc. Seco-mevinic acid derivatives useful as antihypercholesterolemic agents and new intermediates
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Also Published As

Publication number Publication date
KR910003427B1 (ko) 1991-05-31
HUT40398A (en) 1986-12-28
PL147645B1 (en) 1989-07-31
PT81603B (pt) 1988-04-21
DE3581638D1 (de) 1991-03-07
ZA859303B (en) 1987-07-29
IL77199A (en) 1990-02-09
ES549546A0 (es) 1987-12-01
DK369086A (da) 1986-08-01
NZ214402A (en) 1989-01-27
AU599580B2 (en) 1990-07-26
HU198005B (en) 1989-07-28
ATE60571T1 (de) 1991-02-15
AU5230686A (en) 1986-07-01
FI863121A (fi) 1986-07-30
PH24502A (en) 1990-07-18
EP0216785A1 (en) 1987-04-08
PT81603A (en) 1986-01-01
GR852895B (xx) 1986-04-01
EP0216785B1 (en) 1991-01-30
MY100972A (en) 1991-06-15
FI863121A0 (fi) 1986-07-30
JPS62501009A (ja) 1987-04-23
PL256608A1 (en) 1988-01-07
KR870700063A (ko) 1987-02-28
WO1986003488A1 (en) 1986-06-19
ES8800888A1 (es) 1987-12-01

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AHB Application shelved due to non-payment