DK3468573T5 - Behandling af clostridium difficile infektion - Google Patents

Behandling af clostridium difficile infektion Download PDF

Info

Publication number
DK3468573T5
DK3468573T5 DK17814024.0T DK17814024T DK3468573T5 DK 3468573 T5 DK3468573 T5 DK 3468573T5 DK 17814024 T DK17814024 T DK 17814024T DK 3468573 T5 DK3468573 T5 DK 3468573T5
Authority
DK
Denmark
Prior art keywords
treatment
clostridium difficile
difficile infection
infection
clostridium
Prior art date
Application number
DK17814024.0T
Other languages
Danish (da)
English (en)
Other versions
DK3468573T3 (da
Inventor
Yun-Gi Kim
Bernat Olle
Shilpa Reddy
Jason Norman
Juan Patarroyo
Jessica Schneider
Original Assignee
Vedanta Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vedanta Biosciences Inc filed Critical Vedanta Biosciences Inc
Publication of DK3468573T3 publication Critical patent/DK3468573T3/da
Application granted granted Critical
Publication of DK3468573T5 publication Critical patent/DK3468573T5/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747Lactobacilli, e.g. L. acidophilus or L. brevis
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135Bacteria or derivatives thereof, e.g. probiotics
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L5/00Preparation or treatment of foods or foodstuffs, in general; Food or foodstuffs obtained thereby; Materials therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/742Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/14Peptides containing saccharide radicals; Derivatives thereof, e.g. bleomycin, phleomycin, muramylpeptides or vancomycin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/10Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/16Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
    • A23K10/18Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/30Feeding-stuffs specially adapted for particular animals for swines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0031Rectum, anus
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Physiology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK17814024.0T 2016-06-14 2017-06-14 Behandling af clostridium difficile infektion DK3468573T5 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662349914P 2016-06-14 2016-06-14
PCT/US2017/037498 WO2017218680A1 (en) 2016-06-14 2017-06-14 Treatment of clostridium difficile infection

Publications (2)

Publication Number Publication Date
DK3468573T3 DK3468573T3 (da) 2023-10-16
DK3468573T5 true DK3468573T5 (da) 2024-09-09

Family

ID=60664224

Family Applications (1)

Application Number Title Priority Date Filing Date
DK17814024.0T DK3468573T5 (da) 2016-06-14 2017-06-14 Behandling af clostridium difficile infektion

Country Status (13)

Country Link
US (1) US12390498B2 (enExample)
EP (2) EP3468573B1 (enExample)
JP (3) JP7168558B2 (enExample)
KR (4) KR102658297B1 (enExample)
CN (1) CN109562133A (enExample)
AU (2) AU2017285211B2 (enExample)
CA (2) CA3027917C (enExample)
DK (1) DK3468573T5 (enExample)
ES (1) ES2960053T3 (enExample)
FI (1) FI3468573T3 (enExample)
MX (2) MX2018015522A (enExample)
PT (1) PT3468573T (enExample)
WO (1) WO2017218680A1 (enExample)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2018015522A (es) 2016-06-14 2019-07-12 Vedanta Biosciences Inc Tratamiento de infeccion por clostridium difficile.
EP3606325B1 (en) 2017-04-03 2024-09-04 Gusto Global, LLC Rational design of microbial-based biotherapeutics
WO2019089643A1 (en) 2017-10-30 2019-05-09 Seres Therapeutics, Inc. Compositions and methods for treating antibiotic resistance
CN111526882A (zh) * 2017-11-09 2020-08-11 韦丹塔生物科学股份有限公司 用于治疗变态反应的组合物和方法
US12053495B2 (en) 2017-12-11 2024-08-06 Vedanta Biosciences, Inc. Compositions and methods for suppressing pathogenic organisms
BR112020019979A2 (pt) * 2018-03-29 2021-03-09 Seres Therapeutics, Inc. Composições e métodos para tratamento de doenças inflamatórias intestinais
AU2019289190A1 (en) * 2018-06-19 2021-01-07 4D Pharma Research Ltd Dosage form comprising a live biotherapeutic product
AU2019321681A1 (en) * 2018-08-17 2021-02-25 Vedanta Biosciences, Inc. Methods of decreasing dysbiosis and restoring a microbiome
IL265735A (en) 2019-03-31 2019-05-30 Biomica A microbial consortium and its uses
EP3999029A4 (en) * 2019-07-17 2023-07-26 University of Utah Research Foundation CLOSTRIDIA CONSORTIA COMPOSITIONS AND METHODS OF TREATMENT OF OBESITY, METABOLIC SYNDROME AND IRRITABLE BOWEL
GB201911728D0 (en) * 2019-08-15 2019-10-02 Genome Res Ltd Bacterial composistions for the treatment of disease
EP3858363A1 (en) 2020-01-28 2021-08-04 Institut national de recherche pour l'agriculture, l'alimentation et l'environnement Composition for treating intestinal or pulmonary diseases
US20230138517A1 (en) * 2020-02-07 2023-05-04 Dupont Nutrition Biosciences Aps Feed compositions for animal health
GB202007452D0 (en) * 2020-05-19 2020-07-01 Microbiotica Ltd Threrapeutic bacterial composition
KR102617297B1 (ko) 2020-08-21 2023-12-27 서울대학교산학협력단 클로스트리디움 디피실리 감염의 치료 또는 예방용 조성물
KR102269966B1 (ko) * 2021-01-12 2021-06-28 주식회사 바이오뱅크힐링 루미노코쿠스 파에시스 균주, 및 그의 유래의 소포체 및 그의 항염증 및 항균 용도
KR102296288B1 (ko) * 2020-12-31 2021-09-01 주식회사 바이오뱅크힐링 락토바실러스 루테리 균주, 및 그의 유래의 소포체 및 그의 항염증 및 항균 용도
JP2024504697A (ja) 2021-01-21 2024-02-01 ヴェダンタ バイオサイエンシーズ インコーポレーテッド 肝性脳症を処置するための組成物および方法
WO2022178292A1 (en) * 2021-02-18 2022-08-25 Vedanta Biosciences, Inc. Compositions and methods for suppressing pathogenic organisms
AU2022272332A1 (en) * 2021-05-10 2024-01-04 Microba Ip Pty Ltd Compositions and methods for treating disease
WO2023014048A1 (ko) * 2021-08-02 2023-02-09 주식회사 바이오뱅크힐링 비피도박테리움 속 균주 또는 페디오코쿠스 속 균주 및 그의 유래의 소포체 및 그의 항염증 및 항균 용도
KR102351147B1 (ko) * 2021-08-02 2022-01-14 주식회사 바이오뱅크힐링 블라우티아 오베움 균주, 및 그의 유래의 소포체 및 그의 항염증 및 항균 용도
KR102331486B1 (ko) * 2021-08-02 2021-12-01 주식회사 바이오뱅크힐링 비피도박테리움 슈도카테눌라튬 균주, 및 그의 유래의 소포체 및 그의 항염증 및 항균 용도
KR102351146B1 (ko) * 2021-08-02 2022-01-14 주식회사 바이오뱅크힐링 페디오코쿠스 에시디락티시 균주, 및 그의 유래의 소포체 및 그의 항염증 및 항균 용도
KR102351148B1 (ko) * 2021-08-02 2022-01-14 주식회사 바이오뱅크힐링 페디오코쿠스 펜토사세우스 균주, 및 그의 유래의 소포체 및 그의 항염증 및 항균 용도
KR102331483B1 (ko) * 2021-08-02 2021-12-01 주식회사 바이오뱅크힐링 류코노스톡 락티스 균주, 및 그의 유래의 소포체 및 그의 항염증 및 항균 용도
KR102331484B1 (ko) * 2021-08-02 2021-12-01 주식회사 바이오뱅크힐링 블라우티아 마실리엔시스 균주, 및 그의 유래의 소포체 및 그의 항염증 및 항균 용도
KR102351145B1 (ko) * 2021-08-02 2022-01-14 주식회사 바이오뱅크힐링 비피도박테리움 롱검 균주, 및 그의 유래의 소포체 및 그의 항염증 및 항균 용도
KR102331485B1 (ko) * 2021-08-02 2021-12-01 주식회사 바이오뱅크힐링 블라우티아 웩슬러래 균주, 및 그의 유래의 소포체 및 그의 항염증 및 항균 용도
WO2023014054A1 (ko) * 2021-08-02 2023-02-09 주식회사 바이오뱅크힐링 블라우티아 속 균주, 류코노스톡 속 균주 또는 루미노코쿠스 속 균주 및 그의 유래의 소포체 및 그의 항염증 및 항균 용도
KR102792000B1 (ko) * 2021-10-21 2025-04-08 경북대학교 산학협력단 신규한 락토바실러스 루테리 psc102 균주 및 이의 용도
KR102337998B1 (ko) * 2021-11-03 2021-12-14 주식회사 바이오뱅크힐링 로제부리아 파에시스 균주, 및 그의 유래의 소포체 및 그의 항염증 및 항균 용도
WO2023075458A1 (ko) * 2021-10-27 2023-05-04 주식회사 바이오뱅크힐링 신규 균주, 및 그의 유래의 소포체 및 그의 항염증 및 항균 용도
KR102337995B1 (ko) * 2021-11-10 2021-12-14 주식회사 바이오뱅크힐링 아가토바쿨룸 부티리시프로두켄스 균주, 및 그의 유래의 소포체 및 그의 항염증 및 항균 용도
KR102365420B1 (ko) * 2022-01-04 2022-02-23 주식회사 바이오뱅크힐링 로제부리아 인테스티날리스 균주, 및 그의 유래의 소포체 및 그의 항염증 및 항균 용도
KR102444328B1 (ko) * 2022-03-11 2022-09-19 주식회사 바이오뱅크힐링 아나에로스티페스 하드루스 균주, 및 그의 유래의 소포체 및 그의 항염증 및 항균 용도
WO2023132628A1 (ko) * 2022-01-04 2023-07-13 주식회사 바이오뱅크힐링 신규 균주, 및 그의 유래의 소포체 및 그의 항염증 및 항균 용도
WO2023176952A1 (ja) 2022-03-18 2023-09-21 株式会社明治 腸管内での細菌の増殖制御用組成物及びその利用
KR102626400B1 (ko) * 2022-08-31 2024-01-19 주식회사 바이오뱅크힐링 도레아 론기카테나 균주, 및 그의 유래의 소포체 및 그의 항염증 및 항균 용도
KR102628942B1 (ko) * 2023-08-08 2024-01-26 주식회사 바이오뱅크힐링 레비락토바실러스 브레비스 균주, 및 그의 유래의 소포체및 그의 항염증 및 항균 용도
KR102620186B1 (ko) * 2023-08-08 2024-01-04 주식회사 바이오뱅크힐링 리모실락토바실러스 뮤코세 균주, 및 그의 유래의 소포체및 그의 항염증 및 항균 용도
KR102620185B1 (ko) * 2023-08-08 2024-01-04 주식회사 바이오뱅크힐링 블라우티아 호미니스 균주, 및 그의 유래의 소포체및 그의 항염증 및 항균 용도
WO2025033636A1 (ko) * 2023-08-08 2025-02-13 주식회사 바이오뱅크힐링 신규 균주, 및 그의 유래의 소포체 및 그의 항염증 및 항균 용도
WO2025033635A1 (ko) * 2023-08-08 2025-02-13 주식회사 바이오뱅크힐링 신규 균주, 및 그의 유래의 소포체 및 그의 항염증 및 항균 용도
WO2025076184A1 (en) 2023-10-03 2025-04-10 Vedanta Biosciences, Inc. Methods of decreasing dysbiosis and restoring a microbiome
WO2025093777A1 (en) 2023-11-05 2025-05-08 Human Biome Institute S.A. Functional compositions and methods of use thereof in the treatment and recurrence prophylaxis of clostridioides difficile infection and restoration of healthy microbiota
CN117797176B (zh) * 2024-03-01 2024-07-02 南京大学 双孢梭菌在制备治疗非酒精性脂肪性肝病药物中的应用和一种药物

Family Cites Families (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US132A (en) 1837-02-25 Improvement in propelling machinery by magnetism and electro-magnetism
US4205A (en) 1845-09-23 Spark-arrester
US3261761A (en) 1962-05-07 1966-07-19 Arthur W Anderson Method of freeze drying bacterial cultures
ES2248822T3 (es) 1995-09-15 2006-03-16 Dale N. Gerding Procedimientos y composiciones para la prevencion y el tratamiento de enfermedades asociadas al clostridium difficile.
US6368586B1 (en) 1996-01-26 2002-04-09 Brown University Research Foundation Methods and compositions for enhancing the bioadhesive properties of polymers
AUPQ899700A0 (en) 2000-07-25 2000-08-17 Borody, Thomas Julius Probiotic recolonisation therapy
WO2006050479A2 (en) 2004-11-01 2006-05-11 George Mason University Compositions and methods for diagnosing colon disorders
CA2599909C (en) 2005-03-03 2014-12-02 Meiji Dairies Corporation Immune function modulating agents
EP2337569A4 (en) 2008-09-25 2013-04-03 Univ New York COMPOSITIONS AND METHODS FOR CHARACTERIZING AND RESTORING THE STOMACH DARM, SKIN AND NOSE MICROBIOTA
GB0916335D0 (en) 2009-09-17 2009-10-28 Martin W J Medicaments
ES2730828T3 (es) 2010-02-01 2019-11-12 Rebiotix Inc Bacterioterapia para la colitis por Clostridium difficile
WO2011151941A1 (ja) 2010-06-04 2011-12-08 国立大学法人東京大学 制御性t細胞の増殖または集積を誘導する作用を有する組成物
NZ618935A (en) 2010-08-04 2014-03-28 Karma Medical Prod Co Ltd Compositions for fecal floral transplantation and methods for making and using them and devices for delivering them
US9386793B2 (en) 2010-08-20 2016-07-12 New York University Compositions and methods for treating obesity and related disorders by characterizing and restoring mammalian bacterial microbiota
WO2012098358A1 (en) 2011-01-20 2012-07-26 Biopharma Technology Ltd Freeze drying method
CN103561575A (zh) 2011-05-23 2014-02-05 华盛顿州立大学研究基金会 光合色素稳定剂在水果和蔬菜中调控成熟和质量的用途
EP2744890A4 (en) 2011-09-14 2015-07-08 Univ Kingston METHOD FOR TREATING DISORDERS OF THE MAGENDAR SYSTEM
EP4477750A3 (en) 2011-12-01 2025-03-26 The University of Tokyo Human-derived bacteria that induce proliferation or accumulation of regulatory t cells
IN2014DN07752A (enExample) 2012-02-29 2015-05-15 Ethicon Endo Surgery Inc
EP2832859B1 (en) 2012-03-30 2018-07-25 Ajinomoto Co., Inc. Diabetes-inducible bacterium
WO2013171515A1 (en) 2012-05-18 2013-11-21 Genome Research Limited Methods and groups
CN102743420A (zh) 2012-06-06 2012-10-24 上海交通大学 改善肠道菌群结构的方法及应用
WO2014029578A1 (en) 2012-08-24 2014-02-27 Haldor Topsøe A/S Method and catalyzed filter element with improved alkali-resistance for flue gas cleaning
US8906668B2 (en) 2012-11-23 2014-12-09 Seres Health, Inc. Synergistic bacterial compositions and methods of production and use thereof
CN104955466A (zh) 2012-11-23 2015-09-30 赛里斯治疗公司 协同细菌组合物和其制造方法和用途
JP2016509003A (ja) 2013-02-04 2016-03-24 セレス セラピューティクス インコーポレイテッド 組成物および方法
EP2971148A4 (en) 2013-03-14 2016-08-17 Seres Therapeutics Inc METHODS OF DETECTING PATHOGENS AND ENRICHING FROM MATERIALS AND COMPOSITIONS
RU2015140610A (ru) 2013-03-14 2017-04-17 ТЕРАБАЙОМ, ЭлЭлСи Направленная доставка в желудочно-кишечный тракт пробиотических микроорганизмов и/или терапевтических средств
US9669059B2 (en) 2013-03-15 2017-06-06 University Of Florida Research Foundation, Incorporated Butyrogenic bacteria as probiotics to treat clostridium difficile
WO2014145958A2 (en) 2013-03-15 2014-09-18 Seres Health, Inc. Network-based microbial compositions and methods
WO2015006355A2 (en) 2013-07-09 2015-01-15 Puretech Ventures, Llc Compositions containing combinations of bioactive molecules derived from microbiota for treatment of disease
CA2926466C (en) 2013-10-03 2021-11-16 Frederic Bushman Compositions comprising a defined microbiome and methods of use thereof
EP3074027B1 (en) * 2013-11-25 2024-12-18 Seres Therapeutics, Inc. Synergistic bacterial compositions and methods of production and use thereof
US9956282B2 (en) 2013-12-16 2018-05-01 Seres Therapeutics, Inc. Bacterial compositions and methods of use thereof for treatment of immune system disorders
WO2015156419A1 (en) 2014-04-10 2015-10-15 Riken Compositions and methods for induction of th17 cells
US10206958B2 (en) 2014-04-23 2019-02-19 Cornell University Modulation of fat storage in a subject by altering population levels of christensenellaceae in the GI tract
EP3146065B1 (en) 2014-05-19 2024-11-13 Memorial Sloan Kettering Cancer Center Methods and compositions for reducing clostridium difficile infection
SG11201703395PA (en) 2014-10-31 2017-05-30 Whole Biome Inc Methods and compositions relating to microbial treatment and diagnosis of disorders
WO2016086161A1 (en) 2014-11-25 2016-06-02 Memorial Sloan-Kettering Cancer Center Intestinal microbiota and gvhd
MA41020A (fr) 2014-11-25 2017-10-03 Evelo Biosciences Inc Compositions probiotiques et prébiotiques, et leurs procédés d'utilisation pour la modulation du microbiome
BR112017024264B1 (pt) 2015-05-14 2022-07-12 Crestovo Holdings Llc Composições para transplante de flora fecal e métodos de preparação e utilização das mesmas, e dispositivos para sua administração
CA2986203A1 (en) 2015-05-21 2016-11-24 Yeda Research And Development Co. Ltd. Bacterial populations for promoting health
WO2016201053A1 (en) 2015-06-09 2016-12-15 Regents Of The University Of Minnesota Methods for detecting risk of having a bloodstream infection and compositions for reducing the risk
MA41010B1 (fr) 2015-06-15 2020-01-31 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
SMT201900588T1 (it) 2015-06-15 2019-11-13 4D Pharma Res Limited Blautia stercoris e wexlerae per uso nel trattamento di malattie infiammatorie ed autoimmuni
PT3360559T (pt) 2015-06-15 2020-01-06 4D Pharma Res Ltd Composições compreendendo estirpes bacterianas
PL3307288T3 (pl) 2015-06-15 2019-12-31 4D Pharma Research Limited Kompozycje zawierające szczepy bakteryjne
MA41060B1 (fr) 2015-06-15 2019-11-29 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
JP2018519295A (ja) 2015-06-22 2018-07-19 プレジデント アンド フェローズ オブ ハーバード カレッジ 粘膜固有層調節性t細胞の誘導
HK1259347A1 (zh) 2015-07-08 2019-11-29 赛里斯治疗公司 治疗结肠炎的方法
EP3341000A4 (en) 2015-08-24 2019-02-20 Nubyiota LLC SYSTEMS AND METHOD FOR TREATING DYSBIOSIS WITH BACTERIAL POPULATIONS FROM FECALIA
JP2018535254A (ja) 2015-10-26 2018-11-29 クレストヴォ・ホールディングス・エルエルシー 便微生物叢関連療法のための組成物及び方法
GB201520497D0 (en) 2015-11-20 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
HUE036362T2 (hu) 2015-11-20 2018-07-30 4D Pharma Res Ltd Baktériumtörzseket tartalmazó készítmények
GB201520638D0 (en) 2015-11-23 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
GB201520631D0 (en) 2015-11-23 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
EP4233884A3 (en) 2015-11-24 2023-10-04 Seres Therapeutics, Inc. Designed bacterial compositions
PL3313423T3 (pl) 2016-03-04 2019-09-30 4D Pharma Plc Kompozycje zawierające szczepy bakteryjne blautia do leczenia nadwrażliwości trzewnej
US20170290889A1 (en) 2016-04-11 2017-10-12 New York University Methods and compositions for treating dysbiosis and gastrointestinal and inflammatory disorders
MX2018015522A (es) 2016-06-14 2019-07-12 Vedanta Biosciences Inc Tratamiento de infeccion por clostridium difficile.
US9999641B2 (en) 2016-06-14 2018-06-19 Vedanta Biosciences, Inc. Treatment of clostridium difficile infection
WO2018005606A1 (en) 2016-06-28 2018-01-04 Synthetic Biologics, Inc. Microbiome protection from oral antibiotics
WO2018080477A1 (en) 2016-10-26 2018-05-03 The Joan & Irwin Jacobs Technion-Cornell Institute Systems and methods for ultra-fast identification and abundance estimates of microorganisms using a kmer-depth based approach and privacy-preserving protocols
BR112020023933A2 (pt) 2018-05-24 2021-04-27 Seres Therapeutics, Inc. composições bacterianas projetadas e usos destas
AU2019321681A1 (en) 2018-08-17 2021-02-25 Vedanta Biosciences, Inc. Methods of decreasing dysbiosis and restoring a microbiome
JP2024504697A (ja) 2021-01-21 2024-02-01 ヴェダンタ バイオサイエンシーズ インコーポレーテッド 肝性脳症を処置するための組成物および方法

Also Published As

Publication number Publication date
KR20240055124A (ko) 2024-04-26
DK3468573T3 (da) 2023-10-16
KR102862927B1 (ko) 2025-09-23
JP7483828B2 (ja) 2024-05-15
JP7168558B2 (ja) 2022-11-09
MX2018015522A (es) 2019-07-12
US20240123000A1 (en) 2024-04-18
CN109562133A (zh) 2019-04-02
FI3468573T3 (fi) 2023-10-02
AU2024216443A1 (en) 2024-09-19
KR20250140643A (ko) 2025-09-25
KR102554351B1 (ko) 2023-07-13
CA3226196A1 (en) 2017-12-21
EP4282489A3 (en) 2024-01-10
JP2019517828A (ja) 2019-06-27
AU2017285211B2 (en) 2024-06-27
MX2023003461A (es) 2023-04-19
CA3027917C (en) 2024-02-20
JP2024109615A (ja) 2024-08-14
EP4282489A2 (en) 2023-11-29
ES2960053T3 (es) 2024-02-29
WO2017218680A1 (en) 2017-12-21
KR102658297B1 (ko) 2024-04-18
PT3468573T (pt) 2023-10-16
CA3027917A1 (en) 2017-12-21
KR20190030687A (ko) 2019-03-22
EP3468573B1 (en) 2023-08-09
EP3468573A1 (en) 2019-04-17
JP2023017845A (ja) 2023-02-07
EP3468573A4 (en) 2020-03-04
KR20230107416A (ko) 2023-07-14
US12390498B2 (en) 2025-08-19
AU2017285211A1 (en) 2019-01-24

Similar Documents

Publication Publication Date Title
DK3468573T3 (da) Behandling af clostridium difficile infektion
DK3851537T5 (da) Behandling af hyperbilirubinæmi
DK3785717T3 (da) Fremgangsmåder til behandling af coronaviridae-infektioner
DK3684377T3 (da) Fremgangsmåder til behandling af hepatitis-b-infektion
DK3554240T3 (da) Kombinationer af aktive forbindelser
DK3718507T3 (da) Anordninger til behandling af nedre ekstremitetsvaskulatur
DK3461891T3 (da) Nedstrømsbehandling af en alkalisk phosphatase
DK3137169T3 (da) Hæmmere af lysin-specifik demethylase-1
DK3325662T3 (da) Epigenetisk inaktivering af nmt2
DK3466432T3 (da) Fremgangsmåder til behandling af pulmonale non-tuberkuløse mykobakterielle infektioner
DK3154561T3 (da) Modulering af komplementaktivitet
DK3240612T3 (da) Fremgangsmåder til behandling af nethindesygdomme
DK3506904T3 (da) Behandling af demens
DK3099298T3 (da) Kombinationsterapier med zidovudin til behandling af mikrobielle infektioner
DK3458052T3 (da) Kombinationsbehandling af cancer
DK3685847T5 (da) Modulatorer af komplementaktivitet
DK3307267T3 (da) Behandling af multipel sklerose
DK3474822T3 (da) Formuleringer af brincidofovir
DK3318115T3 (da) Maskine til behandling af svinegylle
DK3137078T3 (da) Behandling af hepatitis delta-virusinfektion
DK2897382T3 (da) Forbedring af binaural kilde
DK3113773T3 (da) Krystallinske former af grapiprant
DK3200748T3 (da) Sammensætninger og fremgangsmåder til behandling og profylakse af infektioner på operationssted
DK3297619T3 (da) Terapeutiske anvendelser af L-4-chlorkynurenin
DK3368044T3 (da) Behandling af hepatisk steatose-relateret oligo-ovulation