DK342881A - Nye fenyl-azacykloalkaner - Google Patents
Nye fenyl-azacykloalkanerInfo
- Publication number
- DK342881A DK342881A DK342881A DK342881A DK342881A DK 342881 A DK342881 A DK 342881A DK 342881 A DK342881 A DK 342881A DK 342881 A DK342881 A DK 342881A DK 342881 A DK342881 A DK 342881A
- Authority
- DK
- Denmark
- Prior art keywords
- carbon atoms
- group
- alkyl
- azacycloalkanes
- alkenyl group
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
- C07D213/16—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom containing only one pyridine ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/34—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE7910026 | 1979-12-05 | ||
SE7910026 | 1979-12-05 | ||
PCT/SE1980/000319 WO1981001552A1 (en) | 1979-12-05 | 1980-12-05 | New phenyl-azacycloalkanes |
SE8000319 | 1980-12-05 |
Publications (3)
Publication Number | Publication Date |
---|---|
DK342881A true DK342881A (da) | 1981-07-31 |
DK155793B DK155793B (da) | 1989-05-16 |
DK155793C DK155793C (da) | 1989-10-02 |
Family
ID=20339477
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK342881A DK155793C (da) | 1979-12-05 | 1981-07-31 | Analogifremgangsmaade til fremstilling af 3-substituerede pyrrolidiner eller piperidiner samt 3-substituerede pyrrolidiner eller piperidiner til brug som udgangsmateriale ved fremgangsmaaden |
Country Status (17)
Country | Link |
---|---|
US (1) | US4426386A (da) |
EP (2) | EP0030526B1 (da) |
JP (1) | JPS6135175B2 (da) |
AT (1) | ATE42281T1 (da) |
AU (1) | AU542153B2 (da) |
CA (1) | CA1147339A (da) |
DD (1) | DD155065A5 (da) |
DE (1) | DE3070247D1 (da) |
DK (1) | DK155793C (da) |
ES (3) | ES497489A0 (da) |
FI (1) | FI67371C (da) |
GR (1) | GR72841B (da) |
HU (1) | HU185422B (da) |
IE (1) | IE50674B1 (da) |
PT (1) | PT72172B (da) |
SE (1) | SE8107742L (da) |
WO (1) | WO1981001552A1 (da) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4937346A (en) * | 1979-12-05 | 1990-06-26 | Per Arvid Emil Carlsson | Phenyl-azacykloalkanes |
SE446335B (sv) * | 1982-03-30 | 1986-09-01 | Astra Laekemedel Ab | Ren enantiomer av en metasubstituerad 3-fenyl-1-propylpiperidin |
SE8305362D0 (sv) * | 1983-09-30 | 1983-09-30 | Astra Laekemedel Ab | Novel substituted phenylazacycloalkanes, processes for preparation and pharmaceutical preparations for such compounds |
EP0077607A1 (en) * | 1981-09-17 | 1983-04-27 | Beecham Group Plc | N-substituted 3-aryl piperidines and derivatives thereof |
US4719219A (en) * | 1982-03-30 | 1988-01-12 | Per A. E. Carlsson | Phenyl-azacycloalkanes and use thereof in treatment of central nervous system disorders |
ATE36153T1 (de) * | 1982-10-01 | 1988-08-15 | Hoffmann La Roche | Spaltung von rac. 1-propyl-3-aryl-piperidinen. |
US4593037A (en) * | 1984-07-26 | 1986-06-03 | Pfizer Inc. | 1,3-disubstituted piperidine compounds as neuroleptic agents |
JPH0657695B2 (ja) * | 1985-07-12 | 1994-08-03 | エーザイ株式会社 | 4−シアノピペリジン誘導体 |
US4826869A (en) * | 1988-02-19 | 1989-05-02 | Syntex (U.S.A.) Inc. | N-(lower alkyl)-2-(3'ureidobenzyl)pyrrolidines |
DE3930282A1 (de) * | 1989-09-11 | 1991-03-21 | Boehringer Ingelheim Kg | Verwendung von dopamin-autorezeptor-agonisten bei der behandlung von drogenabhaengigkeit |
GB9113031D0 (en) * | 1991-06-17 | 1991-08-07 | Smithkline Beecham Plc | Compounds |
SE9802546D0 (sv) * | 1998-07-15 | 1998-07-15 | Ross Nicholas Waters | Medicinal product and method for treatment and prevention of dyskinesia |
WO2000057868A2 (en) * | 1999-03-31 | 2000-10-05 | The Procter & Gamble Company | Use of carbamamic acid derivatives for the treatment of viral infections |
US7346938B2 (en) * | 2002-08-02 | 2008-03-25 | Roy W. Mattson, Jr. | Retrofit suction sanitation safety cover |
EP1707558A1 (en) * | 2005-03-21 | 2006-10-04 | Ferrer Internacional, S.A. | Benzoic acid ester compounds, compositions, uses and methods related thereto |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2892842A (en) | 1959-06-30 | Their preparation | ||
DE1144279B (de) * | 1957-09-26 | 1963-02-28 | Robins Co Inc A H | Verfahren zur Herstellung von 3-Aryl-3-hydroxypyrrolidinen und deren Salzen |
FR1248129A (fr) * | 1959-02-12 | 1960-12-09 | Mead Johnson & Co | Procédé de préparation des 1-acyl- et 1-carbalkoxy-3 pyrrolidinols |
US2975193A (en) * | 1959-06-18 | 1961-03-14 | Parke Davis & Co | Organic amine compounds and method of obtaining the same |
NO116115B (da) * | 1962-06-01 | 1969-02-03 | Parke Davis & Co | |
DK104980C (da) * | 1962-06-20 | 1966-08-01 | Parke Davis & Company A Corp O | Fremgangsmåde til fremstilling af optisk aktive eller racemiske 1-methylpyrrolidinderivater eller syreadditionssalte deraf. |
DK104736C (da) * | 1962-06-20 | 1966-06-27 | Parke Davis & Company A Corp O | Fremgangsmåde til fremstilling af optisk aktive eller racemiske pyrrolidin-derivater eller syreadditionssalte deraf. |
DK105337C (da) * | 1962-06-20 | 1966-09-19 | Parke Davis & Company A Corp O | Fremgangsmåde til fremstilling af optisk aktive eller racemiske pyrrolidinforbindelser eller syreadditionssalte deraf. |
DE1470155A1 (de) * | 1963-04-11 | 1969-06-04 | Parke Davis & Co | Neue Pyrrolidinverbindungen,ihre Saeureadditionssalze,sowie Verfahren zu deren Herstellung |
GB1012008A (en) * | 1963-08-01 | 1965-12-01 | Parke Davis & Co | Process for the production of pyrrolidine compounds |
GB1198973A (en) | 1969-02-07 | 1970-07-15 | Parke Davis & Co | Pyrrolidine Compounds with an Unsaturated Substituent and Methods for their Production |
US3635982A (en) * | 1969-04-08 | 1972-01-18 | American Home Prod | Amino-substituted-quinoxalinyloxazolidines and -oxazines |
CH526536A (de) * | 1970-02-05 | 1972-08-15 | Sandoz Ag | Verfahren zur Herstellung neuer 3-Phenylpyrrolidinderivate |
GB1283452A (en) * | 1970-07-24 | 1972-07-26 | Parke Davis & Co | Substituted 1,3-dialkylpyrrolidines and processes for their production |
US3970656A (en) * | 1974-06-11 | 1976-07-20 | Government Of The United States | 1-Alkyl-4-m-hydroxyphenyl-4-propionyl piperidines |
FR2310761A1 (fr) | 1975-05-16 | 1976-12-10 | Roussel Uclaf | Nouveaux derives de la phenyl-piperidine et leurs sels, procede de preparation et application a titre de medicaments |
FR2310762A1 (fr) | 1975-05-16 | 1976-12-10 | Roussel Uclaf | Nouveaux derives n-substitues de la phenyl piperidine et leurs sels, procede de preparation et application a titre de medicaments |
DE2701705A1 (de) * | 1976-01-28 | 1977-08-04 | Sandoz Ag | Neue organische verbindungen, ihre verwendung und herstellung |
FR2340734A1 (fr) * | 1976-02-13 | 1977-09-09 | Roussel Uclaf | Nouveaux derives de la m-trifluoromethylphenyl piperidine et leurs sels, procede de preparation et application a titre de medicaments |
FR2380261A2 (fr) * | 1977-02-11 | 1978-09-08 | Roussel Uclaf | Nouveaux derives de la m-trifluoromethylphenylpiperidine et leurs sels, procede de preparation et application a titre de medicaments |
-
1980
- 1980-12-05 DE DE8080850183T patent/DE3070247D1/de not_active Expired
- 1980-12-05 GR GR63561A patent/GR72841B/el unknown
- 1980-12-05 ES ES497489A patent/ES497489A0/es active Granted
- 1980-12-05 WO PCT/SE1980/000319 patent/WO1981001552A1/en active IP Right Grant
- 1980-12-05 EP EP80850183A patent/EP0030526B1/en not_active Expired
- 1980-12-05 CA CA000366280A patent/CA1147339A/en not_active Expired
- 1980-12-05 HU HU811212A patent/HU185422B/hu not_active IP Right Cessation
- 1980-12-05 PT PT72172A patent/PT72172B/pt not_active IP Right Cessation
- 1980-12-05 EP EP83200131A patent/EP0084920B1/en not_active Expired
- 1980-12-05 IE IE2545/80A patent/IE50674B1/en not_active IP Right Cessation
- 1980-12-05 AU AU66426/81A patent/AU542153B2/en not_active Ceased
- 1980-12-05 DD DD80225781A patent/DD155065A5/de not_active IP Right Cessation
- 1980-12-05 US US06/213,633 patent/US4426386A/en not_active Expired - Lifetime
- 1980-12-05 AT AT83200131T patent/ATE42281T1/de active
- 1980-12-05 JP JP56500175A patent/JPS6135175B2/ja not_active Expired
-
1981
- 1981-07-31 DK DK342881A patent/DK155793C/da not_active IP Right Cessation
- 1981-12-16 ES ES508029A patent/ES8300703A1/es not_active Expired
- 1981-12-16 ES ES508030A patent/ES508030A0/es active Granted
- 1981-12-18 FI FI814080A patent/FI67371C/fi not_active IP Right Cessation
- 1981-12-23 SE SE8107742A patent/SE8107742L/xx not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
EP0084920A3 (en) | 1985-05-22 |
EP0084920A2 (en) | 1983-08-03 |
DK155793B (da) | 1989-05-16 |
DD155065A5 (de) | 1982-05-12 |
PT72172B (en) | 1982-07-05 |
FI814080L (fi) | 1981-12-18 |
HU185422B (en) | 1985-02-28 |
EP0030526B1 (en) | 1985-02-27 |
EP0084920B1 (en) | 1989-04-19 |
ATE42281T1 (de) | 1989-05-15 |
IE50674B1 (en) | 1986-06-11 |
EP0030526A1 (en) | 1981-06-17 |
CA1147339A (en) | 1983-05-31 |
SE8107742L (sv) | 1981-12-23 |
WO1981001552A1 (en) | 1981-06-11 |
JPS56501679A (da) | 1981-11-19 |
ES8205768A1 (es) | 1982-08-01 |
DE3070247D1 (en) | 1985-04-04 |
FI67371B (fi) | 1984-11-30 |
GR72841B (da) | 1983-12-07 |
DK155793C (da) | 1989-10-02 |
JPS6135175B2 (da) | 1986-08-12 |
ES497489A0 (es) | 1982-08-01 |
ES508029A0 (es) | 1982-11-01 |
ES8300092A1 (es) | 1982-10-01 |
ES508030A0 (es) | 1982-10-01 |
ES8300703A1 (es) | 1982-11-01 |
IE802545L (en) | 1981-06-05 |
PT72172A (en) | 1981-01-01 |
US4426386A (en) | 1984-01-17 |
AU6642681A (en) | 1981-06-19 |
FI67371C (fi) | 1985-03-11 |
AU542153B2 (en) | 1985-02-07 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PBP | Patent lapsed |