ES2120483T3 - Alcoholes benzilo y benzhidrilo. - Google Patents

Alcoholes benzilo y benzhidrilo.

Info

Publication number
ES2120483T3
ES2120483T3 ES93304558T ES93304558T ES2120483T3 ES 2120483 T3 ES2120483 T3 ES 2120483T3 ES 93304558 T ES93304558 T ES 93304558T ES 93304558 T ES93304558 T ES 93304558T ES 2120483 T3 ES2120483 T3 ES 2120483T3
Authority
ES
Spain
Prior art keywords
benzilo
benzhidrilo
alcohols
compounds
disclosed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93304558T
Other languages
English (en)
Inventor
Ellen W Baxter
Allen B Reitz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceuticals Inc
Original Assignee
McNeilab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by McNeilab Inc filed Critical McNeilab Inc
Application granted granted Critical
Publication of ES2120483T3 publication Critical patent/ES2120483T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C07D295/112—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)

Abstract

COMPUESTOS DE LA FORMULA I:SE DESCUBREN COMO POTENTES AGENTES ANTIPSICOTICOS. TAMBIEN SE DESCUBREN NUEVOS METODOS DE USO Y PRODUCTOS INTERMEDIOS USADOS PARA HACER EL COMPUESTO DE FORMULA I.
ES93304558T 1992-06-12 1993-06-11 Alcoholes benzilo y benzhidrilo. Expired - Lifetime ES2120483T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/897,487 US5332743A (en) 1992-06-12 1992-06-12 Benzyl and benzhydryl alcohols

Publications (1)

Publication Number Publication Date
ES2120483T3 true ES2120483T3 (es) 1998-11-01

Family

ID=25407975

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93304558T Expired - Lifetime ES2120483T3 (es) 1992-06-12 1993-06-11 Alcoholes benzilo y benzhidrilo.

Country Status (13)

Country Link
US (1) US5332743A (es)
EP (1) EP0574271B1 (es)
JP (1) JP3478405B2 (es)
AT (1) ATE169909T1 (es)
AU (1) AU664093B2 (es)
CA (1) CA2098140A1 (es)
DE (1) DE69320420T2 (es)
DK (1) DK0574271T3 (es)
ES (1) ES2120483T3 (es)
FI (1) FI103885B (es)
NO (1) NO303829B1 (es)
NZ (1) NZ247787A (es)
SG (1) SG76447A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4868148A (en) * 1987-08-24 1989-09-19 Allied-Signal Inc. Layered automotive catalytic composite
CA2091204C (en) * 1992-03-11 1997-04-08 Ronald J. Mattson Antiischemic-piperazinyl and piperidinyl-cyclohexanes
CA2144669A1 (en) * 1994-03-29 1995-09-30 Kozo Akasaka Biphenyl derivatives
US5859246A (en) 1997-01-30 1999-01-12 Neurogen Corporation 1-phenyl-4-benzylpiperazines: dopamine receptor subtype specific ligands
CN109153580B (zh) 2016-05-16 2022-03-22 东曹精细化工株式会社 氧化铝形成用组合物及其制造方法和含有氧化锌粒子或氧化铝粒子的聚烯烃系聚合物纳米复合材料及其制造方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2792398A (en) * 1954-12-03 1957-05-14 Miles Lab Piperazine derivatives
US3497508A (en) * 1966-09-22 1970-02-24 Sandoz Ag Alpha-(2-(morpholinomethyl)phenyl) benzyl alcohols
US3635967A (en) * 1966-09-22 1972-01-18 Sandoz Ag Alpha-(tertiary aminomethyl)-phenyl-alpha pyridyl or c-piperidyl-benzyl alcohols
US3819707A (en) * 1970-06-02 1974-06-25 Sterling Drug Inc 4-(aminoalkylamino)-2-halobenzyl alcohols
US3950393A (en) * 1973-04-13 1976-04-13 Boehringer Ingelheim Gmbh Aminobenzyl-amides and salts thereof
DE3139970A1 (de) * 1981-10-08 1983-04-28 Boehringer Mannheim Gmbh, 6800 Mannheim Neue carbonsaeurederivate, verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittel
US4515793A (en) * 1983-07-27 1985-05-07 Edna Mcconnell Clark Foundation Phenylpiperazines which are useful in the treatment of schistosomiasis
CH664158A5 (fr) * 1984-07-18 1988-02-15 Symphar Sa Derives propylidenediphosphonates-1,3 substitues en position 2, leur procede de preparation et compositions pharmaceutiques les contenant.
NZ240863A (en) * 1991-09-11 1995-04-27 Mcneilab Inc Substituted 4-aryl piperidine and 4-aryl piperazine derivatives, preparation and pharmaceutical compositions thereof

Also Published As

Publication number Publication date
ATE169909T1 (de) 1998-09-15
FI103885B1 (fi) 1999-10-15
FI103885B (fi) 1999-10-15
EP0574271A3 (es) 1994-04-06
US5332743A (en) 1994-07-26
FI932691A (fi) 1993-12-13
EP0574271A2 (en) 1993-12-15
NO932158D0 (no) 1993-06-11
SG76447A1 (en) 2000-11-21
FI932691A0 (fi) 1993-06-11
DE69320420T2 (de) 1999-03-04
NO932158L (no) 1993-12-13
DE69320420D1 (de) 1998-09-24
CA2098140A1 (en) 1993-12-13
DK0574271T3 (da) 1999-05-25
EP0574271B1 (en) 1998-08-19
NO303829B1 (no) 1998-09-07
NZ247787A (en) 1995-10-26
AU664093B2 (en) 1995-11-02
JPH06271538A (ja) 1994-09-27
AU4006893A (en) 1993-12-16
JP3478405B2 (ja) 2003-12-15

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