DK3351240T3 - Formuleringer af 4-amino-2-(2,6-dioxopiperidin-3-yl)isoindolin-1,3-dion - Google Patents
Formuleringer af 4-amino-2-(2,6-dioxopiperidin-3-yl)isoindolin-1,3-dion Download PDFInfo
- Publication number
- DK3351240T3 DK3351240T3 DK18160247.5T DK18160247T DK3351240T3 DK 3351240 T3 DK3351240 T3 DK 3351240T3 DK 18160247 T DK18160247 T DK 18160247T DK 3351240 T3 DK3351240 T3 DK 3351240T3
- Authority
- DK
- Denmark
- Prior art keywords
- dioxopiperidin
- isoindolin
- dion
- formulations
- amino
- Prior art date
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US17967809P | 2009-05-19 | 2009-05-19 | |
EP17151178.5A EP3199149A1 (en) | 2009-05-19 | 2010-05-19 | Formulations of 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione |
Publications (1)
Publication Number | Publication Date |
---|---|
DK3351240T3 true DK3351240T3 (da) | 2019-06-17 |
Family
ID=42635489
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK18160247.5T DK3351240T3 (da) | 2009-05-19 | 2010-05-19 | Formuleringer af 4-amino-2-(2,6-dioxopiperidin-3-yl)isoindolin-1,3-dion |
DK10720107.1T DK2391355T3 (da) | 2009-05-19 | 2010-05-19 | Formuleringer af 4-amino-2-(2,6-dioxopiperidin-3-yl)isoindolin-1,3-dion |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK10720107.1T DK2391355T3 (da) | 2009-05-19 | 2010-05-19 | Formuleringer af 4-amino-2-(2,6-dioxopiperidin-3-yl)isoindolin-1,3-dion |
Country Status (34)
Country | Link |
---|---|
US (6) | US8828427B2 (da) |
EP (3) | EP2391355B1 (da) |
JP (1) | JP5752677B2 (da) |
KR (1) | KR101381060B1 (da) |
CN (3) | CN106176662A (da) |
AU (1) | AU2010249615B2 (da) |
BR (1) | BRPI1007855B1 (da) |
CA (1) | CA2752550C (da) |
CL (1) | CL2011001969A1 (da) |
CO (1) | CO6430422A2 (da) |
CR (1) | CR20110435A (da) |
CY (2) | CY1118632T1 (da) |
DK (2) | DK3351240T3 (da) |
EC (1) | ECSP11011317A (da) |
ES (2) | ES2615511T3 (da) |
HR (2) | HRP20170179T1 (da) |
HU (2) | HUE033115T2 (da) |
IL (2) | IL214644A (da) |
LT (2) | LT3351240T (da) |
MX (2) | MX342330B (da) |
NI (1) | NI201100158A (da) |
NZ (1) | NZ594557A (da) |
PE (1) | PE20120654A1 (da) |
PH (1) | PH12015501523A1 (da) |
PL (2) | PL3351240T3 (da) |
PT (2) | PT3351240T (da) |
RU (1) | RU2479307C1 (da) |
SG (1) | SG174137A1 (da) |
SI (2) | SI3351240T1 (da) |
SM (1) | SMT201700097B (da) |
TR (1) | TR201905423T4 (da) |
UA (1) | UA102582C2 (da) |
WO (1) | WO2010135396A2 (da) |
ZA (1) | ZA201105962B (da) |
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US7968569B2 (en) | 2002-05-17 | 2011-06-28 | Celgene Corporation | Methods for treatment of multiple myeloma using 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione |
US8404716B2 (en) | 2002-10-15 | 2013-03-26 | Celgene Corporation | Methods of treating myelodysplastic syndromes with a combination therapy using lenalidomide and azacitidine |
US11116782B2 (en) | 2002-10-15 | 2021-09-14 | Celgene Corporation | Methods of treating myelodysplastic syndromes with a combination therapy using lenalidomide and azacitidine |
EP2391355B1 (en) | 2009-05-19 | 2017-01-18 | Celgene Corporation | Formulations of 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione |
WO2014160698A1 (en) | 2013-03-26 | 2014-10-02 | Celgene Corporation | SOLID FORMS COMPRISING 4-AMINO-I-β-D-RIBOFURANOSYL-1,3,5-TRIAZIN-2(1H)-ONE AND A COFORMER, COMPOSITIONS AND METHODS OF USE THEREOF |
KR20150136078A (ko) * | 2013-04-02 | 2015-12-04 | 셀진 코포레이션 | 중추신경계 암의 치료 및 관리를 위한 4-아미노-2-(2,6-디옥소-피페리딘-3-일)-이소인돌린-1,3-디온을 사용한 방법 및 조성물 |
EP2815749A1 (en) | 2013-06-20 | 2014-12-24 | IP Gesellschaft für Management mbH | Solid form of 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione having specified X-ray diffraction pattern |
NZ631364A (en) * | 2013-08-08 | 2017-09-29 | Array Biopharma Inc | Filanesib combined with pomalidomide displays enhanced anti-tumor activity |
UA117141C2 (uk) | 2013-10-08 | 2018-06-25 | Селджин Корпорейшн | Склади (s)-3-(4-((4-(морфолінометил)бензил)оксі)-1-оксоізоіндолін-2-іл)піперидин-2,6-діону |
KR20170042598A (ko) | 2014-08-22 | 2017-04-19 | 셀진 코포레이션 | 항체와 조합된 면역조절 화합물을 이용하여 다발성 골수종을 치료하는 방법 |
CN104523692A (zh) * | 2014-12-16 | 2015-04-22 | 南京艾德凯腾生物医药有限责任公司 | 一种泊马度胺复合物及其制备方法 |
RS62352B1 (sr) | 2015-06-29 | 2021-10-29 | Bristol Myers Squibb Co | Imunoterapijski režimi doziranja koji obuhvataju pomalidomid i anti-cs1 antitelo za lečenje kancera |
CN105213392A (zh) * | 2015-09-29 | 2016-01-06 | 浙江大学 | 泊马度胺在制备减轻多发性硬化症的药物中的应用 |
WO2018013689A1 (en) | 2016-07-13 | 2018-01-18 | Celgene Corporation | Solid dispersions and solid forms comprising 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione, method of preparation and use thereof |
WO2018013693A1 (en) | 2016-07-13 | 2018-01-18 | Celgene Corporation | Solid dispersions and cocrystals comprising 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione compositions and methods of use thereof |
RU2019105711A (ru) * | 2016-08-02 | 2020-09-04 | Синтон Б.В. | Фармацевтическая композиция, содержащая помалидомид |
WO2018150435A1 (en) * | 2017-02-18 | 2018-08-23 | Natco Pharma Limited | Pharmaceutical compositions of pomalidomide |
US10093647B1 (en) | 2017-05-26 | 2018-10-09 | Celgene Corporation | Crystalline 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione dihydrate, compositions and methods of use thereof |
JP2020533383A (ja) | 2017-09-14 | 2020-11-19 | グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドGlaxosmithkline Intellectual Property Development Limited | 癌の組合せ治療 |
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US10093648B1 (en) * | 2017-09-22 | 2018-10-09 | Celgene Corporation | Crystalline 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione hemihydrate, compositions and methods of use thereof |
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