DK3339426T3 - Anvendelse af phosphoketolase i fremstillingen af mevalonat, isoprenoid-udgangsstoffer og isopren - Google Patents

Anvendelse af phosphoketolase i fremstillingen af mevalonat, isoprenoid-udgangsstoffer og isopren Download PDF

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Publication number
DK3339426T3
DK3339426T3 DK17206148.3T DK17206148T DK3339426T3 DK 3339426 T3 DK3339426 T3 DK 3339426T3 DK 17206148 T DK17206148 T DK 17206148T DK 3339426 T3 DK3339426 T3 DK 3339426T3
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Prior art keywords
isopren
phosphoketolase
mevalonate
manufacture
starting materials
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DK17206148.3T
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Danish (da)
English (en)
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Zachary Q Beck
Andrew C Eliot
Caroline M Peres
Dmitrii V Vaviline
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Danisco Us Inc
Goodyear Tire & Rubber
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Application filed by Danisco Us Inc, Goodyear Tire & Rubber filed Critical Danisco Us Inc
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Publication of DK3339426T3 publication Critical patent/DK3339426T3/da

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    • C12P5/00Preparation of hydrocarbons or halogenated hydrocarbons
    • C12P5/007Preparation of hydrocarbons or halogenated hydrocarbons containing one or more isoprene units, i.e. terpenes
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    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1085Transferases (2.) transferring alkyl or aryl groups other than methyl groups (2.5)
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    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
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    • C12YENZYMES
    • C12Y203/00Acyltransferases (2.3)
    • C12Y203/01Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/01008Phosphate acetyltransferase (2.3.1.8)
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    • C12Y401/00Carbon-carbon lyases (4.1)
    • C12Y401/02Aldehyde-lyases (4.1.2)
    • C12Y401/02009Phosphoketolase (4.1.2.9)
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    • C12Y402/00Carbon-oxygen lyases (4.2)
    • C12Y402/03Carbon-oxygen lyases (4.2) acting on phosphates (4.2.3)
    • C12Y402/03027Isoprene synthase (4.2.3.27)
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    • C12Y503/00Intramolecular oxidoreductases (5.3)
    • C12Y503/03Intramolecular oxidoreductases (5.3) transposing C=C bonds (5.3.3)
    • C12Y503/03002Isopentenyl-diphosphate DELTA-isomerase (5.3.3.2)
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    • C12Y205/00Transferases transferring alkyl or aryl groups, other than methyl groups (2.5)
    • C12Y205/01Transferases transferring alkyl or aryl groups, other than methyl groups (2.5) transferring alkyl or aryl groups, other than methyl groups (2.5.1)
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/52Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

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  • Chemical & Material Sciences (AREA)
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  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
DK17206148.3T 2011-10-07 2012-10-05 Anvendelse af phosphoketolase i fremstillingen af mevalonat, isoprenoid-udgangsstoffer og isopren DK3339426T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161545083P 2011-10-07 2011-10-07
EP12775413.3A EP2764084B2 (en) 2011-10-07 2012-10-05 Utilization of phosphoketolase in the production of mevalonate, isoprenoid precursors, and isoprene

Publications (1)

Publication Number Publication Date
DK3339426T3 true DK3339426T3 (da) 2022-09-12

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ID=47046886

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Application Number Title Priority Date Filing Date
DK17206148.3T DK3339426T3 (da) 2011-10-07 2012-10-05 Anvendelse af phosphoketolase i fremstillingen af mevalonat, isoprenoid-udgangsstoffer og isopren
DK12775413.3T DK2764084T4 (da) 2011-10-07 2012-10-05 Anvendelse af phosphoketolase i fremstillingen af mevalonat, isoprenoid-udgangsstoffer, og isopren

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DK12775413.3T DK2764084T4 (da) 2011-10-07 2012-10-05 Anvendelse af phosphoketolase i fremstillingen af mevalonat, isoprenoid-udgangsstoffer, og isopren

Country Status (12)

Country Link
US (3) US8993305B2 (https=)
EP (2) EP2764084B2 (https=)
JP (2) JP6420147B2 (https=)
CN (1) CN104053765A (https=)
AU (1) AU2012332996A1 (https=)
BR (1) BR112014008278A2 (https=)
CA (1) CA2851265A1 (https=)
DK (2) DK3339426T3 (https=)
HK (1) HK1201071A1 (https=)
MX (1) MX2014004209A (https=)
SG (1) SG11201401249PA (https=)
WO (1) WO2013066568A1 (https=)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8647642B2 (en) 2008-09-18 2014-02-11 Aviex Technologies, Llc Live bacterial vaccines resistant to carbon dioxide (CO2), acidic PH and/or osmolarity for viral infection prophylaxis or treatment
JP5387756B2 (ja) * 2011-01-20 2014-01-15 トヨタ自動車株式会社 組換え酵母及びこれを用いた物質生産方法
RS54444B1 (sr) 2011-07-12 2016-06-30 Scientist Of Fortune S.A. Rekombinantni mikroorganizmi za proizvodnju korisnih metabolita
WO2013066568A1 (en) 2011-10-07 2013-05-10 Danisco Us Inc. Utilization of phosphoketolase in the production of mevalonate, isoprenoid precursors, and isoprene
WO2013096683A2 (en) * 2011-12-23 2013-06-27 Danisco Us Inc. Enhanced production of isoprene using marine bacterial cells
US20130323820A1 (en) 2012-06-01 2013-12-05 Lanzatech New Zealand Limited Recombinant microorganisms and uses therefor
WO2013181647A2 (en) 2012-06-01 2013-12-05 Danisco Us Inc. Compositions and methods of producing isoprene and/or industrrial bio-products using anaerobic microorganisms
JP2016511630A (ja) 2012-12-21 2016-04-21 ダニスコ・ユーエス・インク 代案の下流メバロン酸経路を使用するイソプレン、イソプレノイド、およびイソプレノイド前駆体の生成
US9518278B2 (en) 2013-03-14 2016-12-13 The Regents Of The University Of California Recombinant microorganisms having a methanol elongation cycle (MEC)
ES2735331T3 (es) * 2013-04-10 2019-12-18 Goodyear Tire & Rubber Fosfocetolasas para mejorar la producción de metabolitos derivados de acetil-coenzima A, isopreno, precursores de isoprenoides e isoprenoides
WO2015002977A1 (en) * 2013-07-01 2015-01-08 Braskem S/A Ap 09 Modified microorganisms and methods of using same for anaerobic coproduction of isoprene and acetic acid
KR102424159B1 (ko) 2013-09-12 2022-07-25 그라디언트 코포레이션 기포 컬럼 응축기와 같은 응축 장치를 포함하는 시스템
US20160376600A1 (en) 2013-11-25 2016-12-29 Genomatica, Inc. Methods for enhancing microbial production of specific length fatty alcohols in the presence of methanol
WO2015084633A1 (en) 2013-12-03 2015-06-11 Genomatica, Inc. Microorganisms and methods for improving product yields on methanol using acetyl-coa synthesis
US10648004B2 (en) 2014-02-20 2020-05-12 Danisco Us Inc. Recombinant microorganisms for the enhanced production of mevalonate, isoprene, isoprenoid precursors, isoprenoids, and acetyl-CoA-derived products
WO2015191638A1 (en) * 2014-06-09 2015-12-17 Massachusetts Institute Of Technology Dynamic knockdown of central metabolism for redirecting glucose-6-phosphate fluxes
WO2016109494A1 (en) * 2014-12-30 2016-07-07 Novogy, Inc. Enhanced production of core lipids in oleaginous yeasts
WO2016134381A1 (en) 2015-02-20 2016-08-25 The Regents Of The University Of California Novel host cells and methods for producing isopentenol from mevalonate
US10676723B2 (en) 2015-05-11 2020-06-09 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
WO2017132924A1 (zh) * 2016-02-04 2017-08-10 中国科学院微生物研究所 一种用于生物合成异戊二烯和异戊烯的酶及其突变体
CN107815424B (zh) * 2016-09-12 2021-03-05 华东理工大学 一种产柠檬烯的解脂耶氏酵母基因工程菌及其应用
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
CN110366594B (zh) * 2016-12-16 2023-12-15 丹尼斯科美国公司 双功能磷酸转酮酶-磷酸转乙酰酶融合多肽
CN109234216B (zh) * 2017-07-10 2022-05-20 上海医药工业研究院 一种生产鲨烯的基因工程菌及其方法
CN108179114B (zh) * 2017-11-27 2021-08-20 南京晓庄学院 产抗厌氧菌化合物的菌株和发酵方法、抗厌氧菌化合物提取及制备方法和使用方法
CA3084263A1 (en) 2017-12-07 2019-06-13 Zymergen Inc. Engineered biosynthetic pathways for production of (6e)-8-hydroxygeraniol by fermentation
BR112020012704A8 (pt) 2017-12-21 2022-03-03 Zymergen Inc Nepetalactol oxidorredutases, nepetalactol sintases, e micróbios capazes de produzir nepetalactona
US11634701B2 (en) * 2018-03-01 2023-04-25 Total Raffinage Chimie Metabolic pathways with increased carbon yield
CN109486720B (zh) * 2018-12-18 2020-08-04 江南大学 一种产l-木酮糖的枯草芽孢杆菌及其应用
US11584944B2 (en) 2019-02-20 2023-02-21 Braskem S.A. Degradation pathway for pentose and hexose sugars
BR112021015719A2 (pt) * 2019-02-20 2021-12-14 Braskem Sa Micro-organismos e métodos para produção de compostos oxigenados a partir de hexoses
CN109929883A (zh) * 2019-04-02 2019-06-25 烟台华康荣赞生物科技有限公司 重组酵母、构建方法和其在制备酪醇及衍生物中的应用
KR102229379B1 (ko) * 2019-06-11 2021-03-19 주식회사 제노포커스 파이토플루엔 고생산성 재조합 미생물 및 이를 이용한 파이토플루엔의 제조방법
US20230272364A1 (en) * 2019-07-11 2023-08-31 Bp Corporation North America Inc. Gluconate dehydratase enzymes and recombinant cells
JP6917434B2 (ja) * 2019-10-25 2021-08-11 長瀬産業株式会社 好気性菌の代謝酵素破壊株およびその培養法
CN112300952B (zh) * 2020-11-27 2023-05-09 华东理工大学 一种产α-蒎烯的解脂耶氏酵母基因工程菌及其应用
US20240200019A1 (en) * 2021-04-29 2024-06-20 Ginkgo Bioworks, Inc. Genetically modified yeast cells and methods of use for increased lipid yield
CN113549562B (zh) * 2021-07-14 2023-10-24 南京师范大学 一种高效生产广藿香醇的工程菌及其构建方法和应用
AU2022334334A1 (en) * 2021-08-24 2024-02-22 Lanzatech, Inc. Microbial fermentation for the production of isoprenoid alcohols and derivatives
CN115948456B (zh) * 2022-10-18 2024-09-17 重庆大学 一种可提升广藿香醇合成量的融合基因及方法

Family Cites Families (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19629568C1 (de) 1996-07-15 1998-01-08 Fraunhofer Ges Forschung Verfahren zur Herstellung von Isopren
GB9614979D0 (en) 1996-07-17 1996-09-04 Newteam Ltd Aerating arrangement primarily for a shower head
US6531303B1 (en) * 1998-07-06 2003-03-11 Arkion Life Sciences Llc Method of producing geranylgeraniol
AU2001278098A1 (en) * 2000-07-31 2002-02-13 Frederick M. Hahn Manipulation of genes of the mevalonate and isoprenoid pathways to create novel traits in transgenic organisms
US7172886B2 (en) 2001-12-06 2007-02-06 The Regents Of The University Of California Biosynthesis of isopentenyl pyrophosphate
SE0200857D0 (sv) 2002-03-19 2002-03-19 Forskarpatent I Syd Ab Metabolic engineering for improved xylose utilisation of saccharomyces cerevisiae
EP1510583A1 (en) 2002-05-10 2005-03-02 Kyowa Hakko Kogyo Co., Ltd. Process for producing mevalonic acid
WO2004033646A2 (en) 2002-10-04 2004-04-22 E.I. Du Pont De Nemours And Company Process for the biological production of 1,3-propanediol with high yield
JP4168870B2 (ja) 2003-08-14 2008-10-22 トヨタ自動車株式会社 プレニルアルコールの製造方法
BRPI0513837B1 (pt) * 2004-07-27 2021-10-13 The Regents Of The University Of California Célula hospedeira saccharomyces cerevisiae geneticamente modificada; composição compreendendo a mesma e método para aumentar a produção de isoprenoides
BRPI0514201B1 (pt) * 2004-08-10 2020-09-15 Ajinomoto Co., Inc Bactéria, e, método para produzir um metabólito útil
RU2004124226A (ru) * 2004-08-10 2006-01-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) Использование фосфокетолазы для продукции полезных метаболитов
WO2007024718A2 (en) 2005-08-19 2007-03-01 The Regents Of The University Of California Genetically modified host cells and use of same for producing isoprenoid compounds
SG172646A1 (en) 2006-05-26 2011-07-28 Amyris Biotechnologies Inc Production of isoprenoids
US7947478B2 (en) 2006-06-29 2011-05-24 The Regents Of The University Of California Short chain volatile hydrocarbon production using genetically engineered microalgae, cyanobacteria or bacteria
JP4986547B2 (ja) 2006-09-04 2012-07-25 株式会社Adeka 新規なアセトアセチルCoA合成酵素、それをコードするDNA配列、当該酵素の製造方法および当該酵素を利用したメバロン酸の製造方法
WO2009005704A1 (en) * 2007-07-03 2009-01-08 The Regents Of The University Of California Methods of increasing isoprenoid or isoprenoid precursor production
JP2010539902A (ja) * 2007-09-20 2010-12-24 アミリス バイオテクノロジーズ,インコーポレイティド イソプレノイドの生産
EP2062967A1 (en) * 2007-11-21 2009-05-27 Technical University of Denmark Genetically engineered aspergillus
AU2008334945C1 (en) 2007-12-13 2013-09-05 Danisco Us Inc. Compositions and methods for producing isoprene
US20110045563A1 (en) 2008-02-06 2011-02-24 The Regents Of The University Of California Short chain volatile isoprene hydrocarbon production using the mevalonic acid pathway in genetically engineered yeast and fungi
EP2285948B1 (en) * 2008-03-03 2014-01-08 Joule Unlimited Technologies, Inc. Engineered co2 fixing microorganisms producing carbon-based products of interest
AU2009240505B2 (en) 2008-04-23 2013-09-05 Danisco Us Inc. Isoprene synthase variants for improved microbial production of isoprene
US7632995B2 (en) 2008-05-09 2009-12-15 Monsanto Technology Llc Plants and seeds of hybrid corn variety CH852179
MX318543B (es) 2008-07-02 2014-03-18 Danisco Us Inc Composiciones y metodos para producir isopreno libre de hidrocarburos de c5 bajo condicion de desacoplamiento y/o intervalos de operacion seguros.
HU3516U (en) 2008-07-31 2008-11-28 Zoltan Kuthi Anti-theft protection of draining for fuel tanks
CA2737158A1 (en) 2008-09-15 2010-03-18 Danisco Us Inc. Increased isoprene production using the archaeal lower mevalonate pathway
ZA201102111B (en) 2008-09-15 2013-10-30 Danisco Us Inc Reduction of carbon dioxide emission during isoprene production by fermentation
SG169641A1 (en) 2008-09-15 2011-04-29 Danisco Us Inc Systems using cell culture for production of isoprene
CA2737195A1 (en) 2008-09-15 2010-03-18 The Goodyear Tire & Rubber Company Conversion of prenyl derivatives to isoprene
SG172806A1 (en) 2008-12-30 2011-08-29 Danisco Us Inc Methods of producing isoprene and a co-product
US20100297749A1 (en) 2009-04-21 2010-11-25 Sapphire Energy, Inc. Methods and systems for biofuel production
AU2010238770A1 (en) 2009-04-23 2011-11-03 Danisco Us Inc. Three-dimensional structure of isoprene synthase and its use thereof for generating variants
JP4760951B2 (ja) 2009-05-08 2011-08-31 トヨタ自動車株式会社 ブタノール生産能を有する組換え微生物及びブタノールの製造方法
TWI434921B (zh) 2009-06-17 2014-04-21 Danisco Us Inc 從生物異戊二烯組合物製造燃料成分之方法及系統
TWI427149B (zh) 2009-06-17 2014-02-21 Danisco Us Inc 使用dxp及mva途徑之改良之異戊二烯製造
SG179157A1 (en) 2009-09-15 2012-05-30 Sapphire Energy Inc A system for transformation of the chloroplast genome of scenedesmus sp. and dunaliella sp.
EP2483401B1 (en) 2009-09-29 2017-06-21 Butamax (TM) Advanced Biofuels LLC Improved yeast production host cells
EP2594648B1 (en) * 2009-11-10 2016-03-16 Massachusetts Institute of Technology Microbial engineering for the production of chemical and pharmaceutical products from the isoprenoid pathway
CA2783976A1 (en) 2009-12-18 2011-06-23 Danisco Us Inc. Purification of isoprene from renewable resources
EP2857518A3 (en) 2009-12-23 2015-04-22 Danisco US Inc. Compositions and methods of PGL for the increased production of isoprene
NZ600585A (en) * 2009-12-29 2014-07-25 Butamax Tm Advanced Biofuels Expression of hexose kinase in recombinant host cells
US8871488B2 (en) 2010-06-18 2014-10-28 Butamax Advanced Biofuels Llc Recombinant host cells comprising phosphoketolases
CA2816306A1 (en) 2010-10-27 2012-05-03 Danisco Us Inc. Isoprene synthase variants for improved production of isoprene
JP5387756B2 (ja) 2011-01-20 2014-01-15 トヨタ自動車株式会社 組換え酵母及びこれを用いた物質生産方法
SG194691A1 (en) 2011-04-29 2013-12-30 Danisco Us Inc Production of mevalonate, isoprene, and isoprenoids using genes encodingpolypeptides having thiolase, hmg-coa synthase and hmg-coa reductase enzymatic activities
RS54444B1 (sr) 2011-07-12 2016-06-30 Scientist Of Fortune S.A. Rekombinantni mikroorganizmi za proizvodnju korisnih metabolita
WO2013066568A1 (en) 2011-10-07 2013-05-10 Danisco Us Inc. Utilization of phosphoketolase in the production of mevalonate, isoprenoid precursors, and isoprene
EP2776571B1 (en) * 2011-11-09 2017-04-12 Amyris, Inc. Production of acetyl-coenzyme a derived isoprenoids
JP6595449B2 (ja) * 2013-03-15 2019-10-23 アミリス, インコーポレイテッド アセチル補酵素a由来化合物を生産するためのホスホケトラーゼおよびホスホトランスアセチラーゼの使用

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DK2764084T4 (da) 2021-12-06
EP3339426A1 (en) 2018-06-27
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AU2012332996A1 (en) 2014-04-24
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