DK3234562T3 - Kalibreringskoncept til amperometrisk creatininsensor med korrigering for endogene modulatorer - Google Patents

Kalibreringskoncept til amperometrisk creatininsensor med korrigering for endogene modulatorer Download PDF

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Publication number
DK3234562T3
DK3234562T3 DK15808403.8T DK15808403T DK3234562T3 DK 3234562 T3 DK3234562 T3 DK 3234562T3 DK 15808403 T DK15808403 T DK 15808403T DK 3234562 T3 DK3234562 T3 DK 3234562T3
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DK
Denmark
Prior art keywords
insensor
creatin
endogenic
amperometric
calibration concept
Prior art date
Application number
DK15808403.8T
Other languages
English (en)
Inventor
Thomas Steen Hansen
Thomas Kjaer
Thomas Pedersen Nygaard
Original Assignee
Radiometer Medical Aps
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Radiometer Medical Aps filed Critical Radiometer Medical Aps
Application granted granted Critical
Publication of DK3234562T3 publication Critical patent/DK3234562T3/da

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28Electrolytic cell components
    • G01N27/30Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
    • G01N27/3274Corrective measures, e.g. error detection, compensation for temperature or hematocrit, calibration
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001Enzyme electrodes
    • C12Q1/002Electrode membranes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001Enzyme electrodes
    • C12Q1/005Enzyme electrodes involving specific analytes or enzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y105/00Oxidoreductases acting on the CH-NH group of donors (1.5)
    • C12Y105/03Oxidoreductases acting on the CH-NH group of donors (1.5) with oxygen as acceptor (1.5.3)
    • C12Y105/03001Sarcosine oxidase (1.5.3.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y305/00Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
    • C12Y305/02Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in cyclic amides (3.5.2)
    • C12Y305/0201Creatininase (3.5.2.10)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/70Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving creatine or creatinine
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/902Oxidoreductases (1.)
    • G01N2333/906Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.7)
    • G01N2333/9065Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.7) acting on CH-NH groups of donors (1.5)
    • G01N2333/90672Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.7) acting on CH-NH groups of donors (1.5) with oxygen as acceptor (1.5.3) in general
    • G01N2333/90677Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.7) acting on CH-NH groups of donors (1.5) with oxygen as acceptor (1.5.3) in general with a definite EC number (1.5.3.-)
    • G01N2333/90683Sarcosine oxidase (1.5.3.1)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/914Hydrolases (3)
    • G01N2333/978Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • G01N2333/986Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in cyclic amides (3.5.2), e.g. beta-lactamase (penicillinase, 3.5.2.6), creatinine amidohydrolase (creatininase, EC 3.5.2.10), N-methylhydantoinase (3.5.2.6)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
DK15808403.8T 2014-12-18 2015-12-14 Kalibreringskoncept til amperometrisk creatininsensor med korrigering for endogene modulatorer DK3234562T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA201400736 2014-12-18
PCT/EP2015/079524 WO2016096683A1 (en) 2014-12-18 2015-12-14 Calibration concept for amperometric creatinine sensor correcting for endogenous modulators

Publications (1)

Publication Number Publication Date
DK3234562T3 true DK3234562T3 (da) 2020-02-03

Family

ID=54849634

Family Applications (1)

Application Number Title Priority Date Filing Date
DK15808403.8T DK3234562T3 (da) 2014-12-18 2015-12-14 Kalibreringskoncept til amperometrisk creatininsensor med korrigering for endogene modulatorer

Country Status (6)

Country Link
US (1) US11209382B2 (da)
EP (1) EP3234562B1 (da)
JP (1) JP6397134B2 (da)
CN (1) CN107110813B (da)
DK (1) DK3234562T3 (da)
WO (1) WO2016096683A1 (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107810409B (zh) * 2015-07-06 2020-08-04 雷迪奥米特医学公司 校正针对钙抑制的crea传感器的方法
KR102519408B1 (ko) * 2019-04-05 2023-04-10 인스트루멘테이션 래보라토리 컴퍼니 다중 효소 바이오센서 및 실온에서의 다중 효소 바이오센서의 안정화

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61270650A (ja) * 1985-05-24 1986-11-29 Matsushita Electric Works Ltd 血液成分定量用試薬とその使用方法
CA1311179C (en) 1987-05-14 1992-12-08 Richard Linn Detwiler Element and method for determination of creatinine or creatine
AT401689B (de) 1993-10-21 1996-11-25 Avl Verbrennungskraft Messtech Verfahren und vorrichtung zum vermischen zweier ausgangslösungen
AT409040B (de) * 2000-08-11 2002-05-27 Roche Diagnostics Gmbh Creatininsensor-kalibration
ES2633729T3 (es) 2001-08-22 2017-09-25 Instrumentation Laboratory Company Método para calibrar sensores electroquímicos
JP4431147B2 (ja) * 2003-11-28 2010-03-10 ラジオメーター・メディカル・アー・ペー・エス 参照溶液
CN1910458B (zh) 2004-01-23 2011-09-07 爱科来株式会社 蛋白质测定方法
JP2005241537A (ja) * 2004-02-27 2005-09-08 Matsushita Electric Ind Co Ltd 被検知物質測定装置
AU2005279615A1 (en) * 2004-09-03 2006-03-09 Prometic Biosciences Inc. 2,4,6-triamino-s-triazine-based compounds which bind to the tail (Fc) portion of immunoglobulins and their use
CN102608176B (zh) * 2005-05-17 2016-08-10 雷迪奥米特医学公司 用二价锰离子溶液稳定或再活化肌酸酐传感器的方法
US20060275859A1 (en) * 2005-05-17 2006-12-07 Kjaer Thomas Enzyme sensor including a water-containing spacer layer
JP4763777B2 (ja) * 2005-05-17 2011-08-31 ラジオメーター・メディカル・アー・ペー・エス 親水性ポリマーで被覆されたカバー膜層を含む酵素センサー
US7699973B2 (en) * 2006-06-30 2010-04-20 Abbott Diabetes Care Inc. Rapid analyte measurement assay
DE102006043718B4 (de) * 2006-09-18 2014-12-31 Alexander Adlassnig Bestimmung von Wasserstoffperoxidkonzentrationen
WO2009121026A1 (en) * 2008-03-28 2009-10-01 Dexcom, Inc. Polymer membranes for continuous analyte sensors
WO2009144881A1 (ja) 2008-05-16 2009-12-03 パナソニック株式会社 クレアチニン濃度の測定方法、測定デバイス、及び測定装置、並びにそれらを用いた塩分量の測定方法、測定デバイス、及び測定装置
US20160007900A1 (en) * 2013-03-01 2016-01-14 The Regents Of The University Of California Point-of-Care Device for Monitoring Renal Function

Also Published As

Publication number Publication date
JP6397134B2 (ja) 2018-09-26
US11209382B2 (en) 2021-12-28
EP3234562B1 (en) 2019-11-13
US20170363568A1 (en) 2017-12-21
CN107110813A (zh) 2017-08-29
WO2016096683A1 (en) 2016-06-23
JP2018500564A (ja) 2018-01-11
EP3234562A1 (en) 2017-10-25
CN107110813B (zh) 2020-04-17

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