DK3152232T3 - Bestemmelse af antigen-genkendelse ved stregkodning af MHC-multimerer - Google Patents

Bestemmelse af antigen-genkendelse ved stregkodning af MHC-multimerer Download PDF

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Publication number
DK3152232T3
DK3152232T3 DK15739508.8T DK15739508T DK3152232T3 DK 3152232 T3 DK3152232 T3 DK 3152232T3 DK 15739508 T DK15739508 T DK 15739508T DK 3152232 T3 DK3152232 T3 DK 3152232T3
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Prior art keywords
determination
antigen recognition
bar coding
mhc multimers
multimers
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DK15739508.8T
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Danish (da)
English (en)
Inventor
Hadrup Sine Reker
Henrik Pedersen
Amalie Kai Bentzen
Søren Jakobsen
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Immudex Aps
Herlev Hospital
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966Animal cells
    • G01N33/56972White blood cells
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/70539MHC-molecules, e.g. HLA-molecules
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K19/00Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1065Preparation or screening of tagged libraries, e.g. tagged microorganisms by STM-mutagenesis, tagged polynucleotides, gene tags
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6804Nucleic acid analysis using immunogens
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70503Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
    • G01N2333/70539MHC-molecules, e.g. HLA-molecules

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Plant Pathology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
DK15739508.8T 2014-06-06 2015-06-08 Bestemmelse af antigen-genkendelse ved stregkodning af MHC-multimerer DK3152232T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA201470340 2014-06-06
PCT/DK2015/050150 WO2015185067A1 (en) 2014-06-06 2015-06-08 Determining antigen recognition through barcoding of mhc multimers

Publications (1)

Publication Number Publication Date
DK3152232T3 true DK3152232T3 (da) 2020-02-24

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DK15739508.8T DK3152232T3 (da) 2014-06-06 2015-06-08 Bestemmelse af antigen-genkendelse ved stregkodning af MHC-multimerer

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US (1) US20170343545A1 (https=)
EP (3) EP3628684B1 (https=)
JP (4) JP6956632B2 (https=)
AU (3) AU2015271324B2 (https=)
CA (2) CA3205428A1 (https=)
DK (1) DK3152232T3 (https=)
ES (1) ES2770634T3 (https=)
PT (1) PT3152232T (https=)
SG (2) SG10202005892SA (https=)
WO (1) WO2015185067A1 (https=)

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EP3152232A1 (en) 2017-04-12
AU2019264685A1 (en) 2019-12-05
JP2025128229A (ja) 2025-09-02
ES2770634T3 (es) 2020-07-02
JP6956632B2 (ja) 2021-11-02
US20170343545A1 (en) 2017-11-30
EP3628684B1 (en) 2024-09-18
EP3152232B1 (en) 2019-11-13
JP2023100746A (ja) 2023-07-19
PT3152232T (pt) 2020-02-19
WO2015185067A1 (en) 2015-12-10
AU2015271324A1 (en) 2017-01-12
CA2951325C (en) 2023-09-12
SG10202005892SA (en) 2020-07-29
CA2951325A1 (en) 2015-12-10
AU2021204496A1 (en) 2021-07-29
JP2020109114A (ja) 2020-07-16
EP3628684C0 (en) 2024-09-18
EP3628684A1 (en) 2020-04-01
JP7271465B2 (ja) 2023-05-11
WO2015185067A9 (en) 2019-06-13
AU2019264685B2 (en) 2021-04-01
EP4484450A3 (en) 2025-03-26
EP4484450A2 (en) 2025-01-01
SG11201610177UA (en) 2017-01-27
AU2015271324B2 (en) 2019-09-12
AU2021204496B2 (en) 2023-07-06
CA3205428A1 (en) 2015-12-10
JP2017518375A (ja) 2017-07-06

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