DK313588D0 - Oxazolidin-2-on-forbindelser og deres anvendelse som hypoglycaemiske midler - Google Patents
Oxazolidin-2-on-forbindelser og deres anvendelse som hypoglycaemiske midlerInfo
- Publication number
- DK313588D0 DK313588D0 DK313588A DK313588A DK313588D0 DK 313588 D0 DK313588 D0 DK 313588D0 DK 313588 A DK313588 A DK 313588A DK 313588 A DK313588 A DK 313588A DK 313588 D0 DK313588 D0 DK 313588D0
- Authority
- DK
- Denmark
- Prior art keywords
- oxazolidin
- pharmaceutically
- compounds
- salt
- hypoglycaemic agents
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/18—Oxygen atoms
- C07D263/20—Oxygen atoms attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/18—Oxygen atoms
- C07D263/20—Oxygen atoms attached in position 2
- C07D263/22—Oxygen atoms attached in position 2 with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to other ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/48—Nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US1987/001356 WO1988009661A1 (en) | 1987-06-10 | 1987-06-10 | Oxazolidin-2-one derivatives as hypoglycemic agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK313588D0 true DK313588D0 (da) | 1988-06-09 |
| DK313588A DK313588A (da) | 1989-02-10 |
Family
ID=22202413
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK313588A DK313588A (da) | 1987-06-10 | 1988-06-09 | Oxazolidin-2-on-forbindelser og deres anvendelse som hypoglycaemiske midler |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US4968707A (da) |
| EP (1) | EP0294995B1 (da) |
| JP (1) | JPS649979A (da) |
| KR (1) | KR900007313B1 (da) |
| AT (1) | ATE82284T1 (da) |
| AU (1) | AU585196B2 (da) |
| CA (1) | CA1305152C (da) |
| DE (1) | DE3875806T2 (da) |
| DK (1) | DK313588A (da) |
| ES (1) | ES2045116T3 (da) |
| FI (1) | FI89479C (da) |
| GR (1) | GR3007059T3 (da) |
| HU (1) | HU203330B (da) |
| IE (1) | IE62029B1 (da) |
| IL (1) | IL86603A (da) |
| MY (1) | MY103297A (da) |
| NO (1) | NO171978C (da) |
| NZ (1) | NZ224957A (da) |
| PT (1) | PT87702B (da) |
| WO (1) | WO1988009661A1 (da) |
| ZA (1) | ZA884114B (da) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH02167224A (ja) * | 1988-09-13 | 1990-06-27 | Tanabe Seiyaku Co Ltd | 抗脂血剤 |
| US5356908A (en) * | 1989-04-21 | 1994-10-18 | E. I. Du Pont De Nemours And Company | Fungicidal oxazolidinones |
| WO1991003474A1 (en) * | 1989-08-29 | 1991-03-21 | Pfizer Inc. | Hypoglycemic thiazolidinedione derivatives |
| US5068342A (en) * | 1989-10-27 | 1991-11-26 | American Home Products Corporation | 5-[(1- and 2-naphthalenyl)thio and sulfonyl]-2,4-thiazolidinediones and derivatives thereof |
| CA2083891A1 (en) * | 1991-12-03 | 1993-06-04 | Angus Murray Macleod | Heterocyclic compounds, compositions containing them and their use in therapy |
| BR9306201A (pt) * | 1992-04-07 | 1998-06-23 | Pfizer | Derivados de indol como agonistas 5-ht1 |
| ES2139633T3 (es) | 1992-08-31 | 2000-02-16 | Sankyo Co | Derivados de oxazolidina con propiedades anti-diabetica y anti-obesidad, su preparacion y su utilizacion terapeutica. |
| EP0645387A1 (en) * | 1993-04-07 | 1995-03-29 | Taiho Pharmaceutical Co., Ltd. | Thiazolidine derivative and pharmaceutical composition containing the same |
| US5629200A (en) * | 1993-11-18 | 1997-05-13 | Daicel Chemical Industries, Ltd. | Production of optically active 2-amino-1-phenylethanol derivatives by asymetrical assimilation |
| IL113084A (en) * | 1994-03-23 | 1999-01-26 | Sankyo Co | Derivatives of thiazolidine and oxazolidine, processes for their preparation and pharmaceutical preparations containing them |
| US7482366B2 (en) | 2001-12-21 | 2009-01-27 | X-Ceptor Therapeutics, Inc. | Modulators of LXR |
| ES2421511T3 (es) | 2001-12-21 | 2013-09-03 | X Ceptor Therapeutics Inc | Moduladores de LXR |
| DOP2005000123A (es) * | 2004-07-02 | 2011-07-15 | Merck Sharp & Dohme | Inhibidores de cetp |
| AU2005319167B2 (en) * | 2004-12-21 | 2011-09-29 | Gilead Sciences, Inc. | Imidazo[4,5-C]pyridine compound and method of antiviral treatment |
| TW200732313A (en) * | 2005-12-15 | 2007-09-01 | Astrazeneca Ab | Oxazolidinone compounds and their use as metabotropic glutamate receptor potentiators |
| US7915271B2 (en) * | 2005-12-30 | 2011-03-29 | Merck Sharp & Dohme Corp. | 1,3-oxazolidin-2-one derivatives useful as CETP inhibitors |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2909467A (en) * | 1958-07-09 | 1959-10-20 | Us Vitamin Pharm Corp | 3-(d-alpha-methylphenethyl)-5-methyl-1, 3-oxazolidine-2, 4-dione |
| JPS5522636A (en) * | 1978-08-04 | 1980-02-18 | Takeda Chem Ind Ltd | Thiazoliding derivative |
| DD153682A1 (de) * | 1978-10-19 | 1982-01-27 | Horst Bercher | Verfahren zur herstellung neuer alkanolamine |
| EP0040915B1 (en) * | 1980-05-22 | 1984-03-21 | Beecham Group Plc | Arylethanolamine derivatives, their preparation and use in pharmaceutical compositions |
| SG56656G (en) * | 1980-07-28 | 1987-03-27 | Pfizer | Hypoglycemic 5-substituted oxazolidine-2, 4-diones |
| US4407811A (en) * | 1981-01-02 | 1983-10-04 | Pfizer Inc. | Hypoglycemic 5-substituted oxazolidine-2,4-diones |
| ES8400116A1 (es) * | 1981-10-13 | 1983-10-16 | Pfizer | "un procedimiento por analogia para la preparacion de derivados de espiro-oxindol-oxazolidindiona". |
| GR78120B (da) * | 1982-03-01 | 1984-09-26 | Pfizer | |
| JPS58183676A (ja) * | 1982-04-19 | 1983-10-26 | Takeda Chem Ind Ltd | オキサゾ−ル誘導体 |
| US4430337A (en) * | 1982-06-23 | 1984-02-07 | Pfizer Inc. | Alicyclic substituted oxazolidine-2,4-diones having hypoglycemic activity |
| US4617312A (en) * | 1983-01-17 | 1986-10-14 | Pfizer Inc. | Aldose reductase inhibiting 5-(2-alkoxyphenyl) thiazolidinediones |
| EP0140359B1 (en) * | 1983-11-02 | 1989-01-25 | Beecham Group Plc | Morpholine derivatives |
| EP0142102B1 (en) * | 1983-11-04 | 1987-09-23 | Beecham Group Plc | Tertiary amines |
| CA1249992A (en) * | 1983-11-10 | 1989-02-14 | Marcel Muller | Oxazolidines |
| GB8412862D0 (en) * | 1984-05-19 | 1984-06-27 | Beecham Group Plc | Compounds |
| GB8418657D0 (en) * | 1984-07-21 | 1984-08-22 | Beecham Group Plc | Compounds |
| WO1986002073A1 (en) * | 1984-10-03 | 1986-04-10 | Takeda Chemical Industries, Ltd. | Thiazolidinedione derivatives, process for their preparation, and pharmaceutical composition containing same |
| DE3438839A1 (de) * | 1984-10-19 | 1986-04-24 | Schering AG, 1000 Berlin und 4709 Bergkamen | Pharmazeutische praeparate |
| AR240698A1 (es) * | 1985-01-19 | 1990-09-28 | Takeda Chemical Industries Ltd | Procedimiento para preparar compuestos de 5-(4-(2-(5-etil-2-piridil)-etoxi)benzil)-2,4-tiazolidindiona y sus sales |
| US4738972A (en) * | 1985-05-21 | 1988-04-19 | Pfizer Inc. | Hypoglycemic thiazolidinediones |
| JPH06779B2 (ja) * | 1985-06-10 | 1994-01-05 | 武田薬品工業株式会社 | チアゾリジオン誘導体およびそれを含んでなる医薬組成物 |
| US4812570A (en) * | 1986-07-24 | 1989-03-14 | Takeda Chemical Industries, Ltd. | Method for producing thiazolidinedione derivatives |
| US4873255A (en) * | 1987-02-04 | 1989-10-10 | Sankyo Company Limited | Thiazolidinone derivatives, their preparation and their use |
| EP0295828A1 (en) * | 1987-06-13 | 1988-12-21 | Beecham Group Plc | Novel compounds |
| US4791125A (en) * | 1987-12-02 | 1988-12-13 | Pfizer Inc. | Thiazolidinediones as hypoglycemic and anti-atherosclerosis agents |
-
1987
- 1987-06-10 HU HU874223A patent/HU203330B/hu not_active IP Right Cessation
- 1987-06-10 US US07/460,848 patent/US4968707A/en not_active Expired - Fee Related
- 1987-06-10 WO PCT/US1987/001356 patent/WO1988009661A1/en active IP Right Grant
-
1988
- 1988-06-01 ES ES88304976T patent/ES2045116T3/es not_active Expired - Lifetime
- 1988-06-01 AT AT88304976T patent/ATE82284T1/de active
- 1988-06-01 DE DE8888304976T patent/DE3875806T2/de not_active Expired - Fee Related
- 1988-06-01 EP EP88304976A patent/EP0294995B1/en not_active Expired - Lifetime
- 1988-06-02 IL IL86603A patent/IL86603A/xx not_active IP Right Cessation
- 1988-06-06 MY MYPI88000601A patent/MY103297A/en unknown
- 1988-06-07 JP JP63139787A patent/JPS649979A/ja active Granted
- 1988-06-08 CA CA000568902A patent/CA1305152C/en not_active Expired - Fee Related
- 1988-06-09 KR KR1019880006908A patent/KR900007313B1/ko not_active IP Right Cessation
- 1988-06-09 AU AU17534/88A patent/AU585196B2/en not_active Ceased
- 1988-06-09 PT PT87702A patent/PT87702B/pt not_active IP Right Cessation
- 1988-06-09 IE IE173488A patent/IE62029B1/en not_active IP Right Cessation
- 1988-06-09 NZ NZ224957A patent/NZ224957A/xx unknown
- 1988-06-09 ZA ZA884114A patent/ZA884114B/xx unknown
- 1988-06-09 DK DK313588A patent/DK313588A/da not_active Application Discontinuation
-
1989
- 1989-02-08 NO NO89890529A patent/NO171978C/no unknown
- 1989-12-05 FI FI895815A patent/FI89479C/fi not_active IP Right Cessation
-
1993
- 1993-02-11 GR GR930400291T patent/GR3007059T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL86603A (en) | 1992-09-06 |
| GR3007059T3 (da) | 1993-07-30 |
| IE881734L (en) | 1988-12-10 |
| DK313588A (da) | 1989-02-10 |
| NO890529D0 (no) | 1989-02-08 |
| IE62029B1 (en) | 1994-12-14 |
| ZA884114B (en) | 1990-02-28 |
| FI89479C (fi) | 1993-10-11 |
| EP0294995A1 (en) | 1988-12-14 |
| KR900007313B1 (ko) | 1990-10-08 |
| MY103297A (en) | 1993-05-29 |
| NO171978C (no) | 1993-05-26 |
| US4968707A (en) | 1990-11-06 |
| EP0294995B1 (en) | 1992-11-11 |
| IL86603A0 (en) | 1988-11-30 |
| PT87702A (pt) | 1988-07-01 |
| JPH0448791B2 (da) | 1992-08-07 |
| ATE82284T1 (de) | 1992-11-15 |
| KR890000447A (ko) | 1989-03-14 |
| WO1988009661A1 (en) | 1988-12-15 |
| NO171978B (no) | 1993-02-15 |
| DE3875806T2 (de) | 1993-04-08 |
| NZ224957A (en) | 1990-03-27 |
| AU1753488A (en) | 1988-12-15 |
| CA1305152C (en) | 1992-07-14 |
| JPS649979A (en) | 1989-01-13 |
| HUT53623A (en) | 1990-11-28 |
| FI895815A0 (fi) | 1989-12-05 |
| FI89479B (fi) | 1993-06-30 |
| PT87702B (pt) | 1992-10-30 |
| AU585196B2 (en) | 1989-06-08 |
| NO890529L (no) | 1989-02-08 |
| DE3875806D1 (de) | 1992-12-17 |
| ES2045116T3 (es) | 1994-01-16 |
| HU203330B (en) | 1991-07-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHB | Application shelved due to non-payment |