DK2848681T3 - Isolering, identifikation og karakterisering af stammer med probiotisk aktivitet fra fæces fra børn, der udelukkende er fodret med modermælk - Google Patents

Isolering, identifikation og karakterisering af stammer med probiotisk aktivitet fra fæces fra børn, der udelukkende er fodret med modermælk Download PDF

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DK2848681T3
DK2848681T3 DK14190638.8T DK14190638T DK2848681T3 DK 2848681 T3 DK2848681 T3 DK 2848681T3 DK 14190638 T DK14190638 T DK 14190638T DK 2848681 T3 DK2848681 T3 DK 2848681T3
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strain
lactobacillus
bacteria
vol
strains
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DK14190638.8T
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Fernández José María Vieites
Quezada Sergio Muñoz
Company Inmaculada Llamas
Lozano José Maldonado
Braquehais Fernando Romero
García Antonio Francisco Suárez
Hernández Ángel Gil
Llorente Carolina Gómez
Brito Miriam Bermúdez
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Hero Ag
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747Lactobacilli, e.g. L. acidophilus or L. brevis
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
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    • A23L33/135Bacteria or derivatives thereof, e.g. probiotics
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/40Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/745Bifidobacteria
    • AHUMAN NECESSITIES
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    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2400/00Lactic or propionic acid bacteria
    • A23V2400/11Lactobacillus
    • A23V2400/175Rhamnosus
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2400/00Lactic or propionic acid bacteria
    • A23V2400/51Bifidobacterium
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    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
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    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/225Lactobacillus

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  • Organic Chemistry (AREA)
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  • Animal Behavior & Ethology (AREA)
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  • Wood Science & Technology (AREA)
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Claims (23)

  1. DK/EP 2848681 T3
    1. Stamme af en probiotisk mikroorganisme isoleret fra fæces fra børn, der udelukkende er fodret med modermælk, kendetegnet ved, at den består af Lactobacillus paracasei HERO 7 med deponeringsnummer CNCM I-4034, deponeret den 2. juli 2008 hos CNCM National Collection of Microorganism Culture, Pasteur Institute 25, Rue du Docteur Roux, F-75724 Paris.
  2. 2. Mikroorganismestamme ifølge krav 1, kendetegnet ved, at den foreligger i form af en ren biologisk kultur.
  3. 3. Mikroorganismestamme ifølge et hvilket som helst af de foregående krav, kendetegnet ved, at den er isoleret.
  4. 4. Stamme af en probiotisk mikroorganisme ifølge et hvilket som helst af de foregående krav, kendetegnet ved, at den foreligger i form af levedygtige celler.
  5. 5. Stamme af en probiotisk mikroorganisme ifølge krav 1 til 3, kendetegnet ved, at den foreligger i form af ikke-levedygtige celler.
  6. 6. Præparat omfattende en stamme af en mikroorganisme ifølge et hvilket som helst af de foregående krav.
  7. 7. Præparat ifølge krav 6, kendetegnet ved, at det desuden omfatter et andet probiotisk materiale.
  8. 8. Præparat ifølge krav 6 til 7, kendetegnet ved, at det endvidere omfatter præbiotisk materiale.
  9. 9. Præparat ifølge et hvilket som helst af kravene 6 til 8, kendetegnet ved, at det endvidere omfatter en til dets indtagelse egnet bærer.
  10. 10. Præparat ifølge krav 9, kendetegnet ved, at bæreren er en farmaceutisk acceptabel bærer, såsom kapsler, tabletter eller pulver.
  11. 11. Præparat ifølge krav 9, kendetegnet ved, at bæreren er et levnedsmiddelprodukt. DK/EP 2848681 T3
  12. 12. Præparat ifølge krav 11, kendetegnet ved, at det nævnte levnedsmiddelprodukt er valgt fra gruppen, der består af mælk og af mælk afledte produkter, især fermenteret mælk og ost; kornsorter og afledte produkter, herunder brøddej; supper og produkter i dehydratiseret form; fermenterede kødprodukter; af frugt afledte produkter, safter og sodavand; levnedsmidler til særlige ernæringsanvendelser.
  13. 13. Stamme af en probiotisk mikroorganisme ifølge et hvilket som helst af kravene 1 til 5 eller præparat ifølge et hvilket som helst af kravene 6 til 12 til anvendelse i diæter.
  14. 14. Stamme ifølge krav 1 til 5 eller præparat ifølge krav 13 til anvendelse i spædbørns-og/eller voksen- og/eller specialdiæter.
  15. 15. Stamme ifølge krav 1 til 5 eller præparat ifølge krav 14 til anvendelse ved fremstillingen af modermælkserstatning.
  16. 16. Stamme ifølge krav 1 til 5 eller præparat ifølge krav 15, kendetegnet ved, at mælkeerstatningen består affærdig børnemælk og/eller børnegrød og/eller børnemad.
  17. 17. Stamme ifølge krav 1 til 5 eller præparat ifølge krav 13 til anvendelse ved fremstillingen af kosttilskud.
  18. 18. Stamme ifølge krav 1 til 5 eller præparat ifølge krav 13 til anvendelse ved fremstillingen af særlige præparater til oral og/eller enteral ernæring.
  19. 19. Stamme ifølge krav 1 til 5 eller præparat ifølge et hvilket som helst af kravene 6 til 10 til anvendelse ved fremstillingen af et farmaceutisk produkt.
  20. 20. Stamme ifølge krav 1 til 5 eller præparat ifølge et hvilket som helst af kravene 6 til 10 til anvendelse ved stimulering af immunsystemet og/eller ved forebyggelse/behandling af astma og/eller ved forebyggelse/behandling af mavetarmlidelser og/eller ved eliminering/modulering af de vigtigste pathogener i fordøjelseskanalen og/eller ved forebyggelse/behandling af obesitet og dens følgesygdomme, herunder metabolisk syndrom og diabetes, og/eller ved de typiske aldersbetingede sygdomme.
  21. 21. Stamme ifølge krav 1 til 5 eller præparat ifølge krav 6 til 10 til anvendelse ifølge krav 20, kendetegnet ved, at mavetarmlidelserne omfatter forandringer i tarmpassagen, DK/EP 2848681 T3 såsom forstoppelse, og forandringer i biotilgængeligheden af mineraler, infektioner og malabsorptionssyndromer.
  22. 22. Stamme ifølge krav 1 til 5 eller præparat ifølge krav 6 til 10 til anvendelse ifølge krav 21, kendetegnet ved, at infektionerne omfatter maveinfektioner og mavetarminfek-tioner med akut eller kronisk diarré.
  23. 23. Stamme ifølge krav 1 til 5 eller præparat ifølge krav 6 til 10, til anvendelse ifølge krav 21, kendetegnet ved, at malabsorptionssyndromerne omfatter lidelser, der rammer tarmenes anatomi, såsom korttarmssyndrom, og lidelser, der rammer tarmenes fysiologi, såsom cystisk fibrose i pankreas, malabsorption af sukkerarter, især lactose, forandringer i lipidabsorption, levnedsmiddelallergier og colitis, såsom Crohn's sygdom og colitis ulcerosa.
DK14190638.8T 2009-03-10 2010-03-09 Isolering, identifikation og karakterisering af stammer med probiotisk aktivitet fra fæces fra børn, der udelukkende er fodret med modermælk DK2848681T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/ES2009/000130 WO2010103132A1 (es) 2009-03-10 2009-03-10 Aislamiento, identificación y caracterización de cepas con actividad probiótica a partir de heces de lactantes alimentados exclusivamente con leche materna
EP10750390.6A EP2407532B1 (en) 2009-03-10 2010-03-09 Isolation, identification and characterisation of strains with probiotic activity, from faeces of infants fed exclusively with breast milk

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DK2848681T3 true DK2848681T3 (da) 2017-07-24

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DK14190638.8T DK2848681T3 (da) 2009-03-10 2010-03-09 Isolering, identifikation og karakterisering af stammer med probiotisk aktivitet fra fæces fra børn, der udelukkende er fodret med modermælk
DK14190648.7T DK2848682T3 (da) 2009-03-10 2010-03-09 Isolation, identifikation og karakterisering af stammer med probiotisk aktivitet fra fæces fra børn, der udelukkende er fodret med modermælk
DK10750390.6T DK2407532T3 (da) 2009-03-10 2010-03-09 Isolering, identifikation og karakterisering af stammer med probiotisk aktivitet fra fæces fra spædbørn, der udelukkende er fodret med modermælk

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DK14190648.7T DK2848682T3 (da) 2009-03-10 2010-03-09 Isolation, identifikation og karakterisering af stammer med probiotisk aktivitet fra fæces fra børn, der udelukkende er fodret med modermælk
DK10750390.6T DK2407532T3 (da) 2009-03-10 2010-03-09 Isolering, identifikation og karakterisering af stammer med probiotisk aktivitet fra fæces fra spædbørn, der udelukkende er fodret med modermælk

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US (3) US8637297B2 (da)
EP (3) EP2407532B1 (da)
CN (3) CN102421889B (da)
DK (3) DK2848681T3 (da)
ES (3) ES2636944T3 (da)
PL (3) PL2407532T3 (da)
RU (1) RU2551315C2 (da)
WO (2) WO2010103132A1 (da)

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