DK246886D0 - Vandig parenteral oploesning af t-pa - Google Patents

Vandig parenteral oploesning af t-pa

Info

Publication number
DK246886D0
DK246886D0 DK246886A DK246886A DK246886D0 DK 246886 D0 DK246886 D0 DK 246886D0 DK 246886 A DK246886 A DK 246886A DK 246886 A DK246886 A DK 246886A DK 246886 D0 DK246886 D0 DK 246886D0
Authority
DK
Denmark
Prior art keywords
ahead
parenteral solution
parenteral
solution
ahead parenteral
Prior art date
Application number
DK246886A
Other languages
English (en)
Other versions
DK163174B (da
DK246886A (da
DK163174C (da
Inventor
Michael Denis Johnston
Henry Berger
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB858513358A external-priority patent/GB8513358D0/en
Priority claimed from GB858521704A external-priority patent/GB8521704D0/en
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of DK246886D0 publication Critical patent/DK246886D0/da
Publication of DK246886A publication Critical patent/DK246886A/da
Publication of DK163174B publication Critical patent/DK163174B/da
Application granted granted Critical
Publication of DK163174C publication Critical patent/DK163174C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • C12N9/6459—Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21069—Protein C activated (3.4.21.69)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Enzymes And Modification Thereof (AREA)
DK246886A 1985-05-28 1986-05-27 Vandig koncentreret parenteral oploesning af vaevs-plasminogenaktivater (t-pa) og fremgangsmaade til fremstilling heraf DK163174C (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB858513358A GB8513358D0 (en) 1985-05-28 1985-05-28 Formulation
GB8513358 1985-08-31
GB858521704A GB8521704D0 (en) 1985-08-31 1985-08-31 Formulation
GB8521704 1985-08-31

Publications (4)

Publication Number Publication Date
DK246886D0 true DK246886D0 (da) 1986-05-27
DK246886A DK246886A (da) 1986-11-29
DK163174B DK163174B (da) 1992-02-03
DK163174C DK163174C (da) 1992-06-22

Family

ID=26289289

Family Applications (1)

Application Number Title Priority Date Filing Date
DK246886A DK163174C (da) 1985-05-28 1986-05-27 Vandig koncentreret parenteral oploesning af vaevs-plasminogenaktivater (t-pa) og fremgangsmaade til fremstilling heraf

Country Status (22)

Country Link
US (1) US5112609A (da)
AT (1) AT391812B (da)
AU (1) AU569429B2 (da)
BE (1) BE904831A (da)
CA (1) CA1297008C (da)
CH (1) CH664495A5 (da)
DE (1) DE3617753A1 (da)
DK (1) DK163174C (da)
ES (1) ES8706443A1 (da)
FI (1) FI85334C (da)
FR (1) FR2593393B1 (da)
GB (1) GB2176703B (da)
GR (1) GR861365B (da)
HU (1) HU200695B (da)
IL (1) IL78937A (da)
IT (1) IT1191925B (da)
LU (1) LU86445A1 (da)
NL (1) NL8601354A (da)
NO (1) NO171344C (da)
NZ (1) NZ216306A (da)
PT (1) PT82647B (da)
SE (1) SE462893B (da)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI831484L (fi) * 1982-05-05 1983-11-06 Genentech Inc Plasminogen aktivator foer maenskovaevnad
SU1662352A3 (ru) * 1982-05-05 1991-07-07 Генентек, Инк (Фирма) Штамм бактерий ЕSснеRIснIа coLI - продуцент активатора плазминогена тканевого типа
US5185259A (en) * 1982-05-05 1993-02-09 Genentech, Inc. Truncated human tissue plasminogen activator
DE3686684T2 (de) * 1985-03-06 1993-01-28 Survival Technology Mittel zur absorptionsverbesserung von proteinen.
ZW14486A1 (en) * 1985-07-29 1986-10-22 Smithkline Beckman Corp Pharmaceutical dosage unit
US4777043A (en) * 1985-12-17 1988-10-11 Genentech, Inc. Stabilized human tissue plasminogen activator compositions
US5034225A (en) * 1985-12-17 1991-07-23 Genentech Inc. Stabilized human tissue plasminogen activator compositions
DK237187A (da) * 1986-05-12 1987-11-13 Wellcome Found Farmaceutisk anvendelse af t-pa
US4976959A (en) * 1986-05-12 1990-12-11 Burroughs Wellcome Co. T-PA and SOD in limiting tissue damage
GB8619098D0 (en) * 1986-08-05 1986-09-17 Wellcome Found Combination
US5149533A (en) * 1987-06-04 1992-09-22 Zymogenetics, Inc. Modified t-PA with kringle-/replaced by another kringle
US5270198A (en) * 1988-05-20 1993-12-14 Genentech, Inc. DNA molecules encoding variants of tissue plasminogen activators, vectors, and host cells
GB8814604D0 (en) * 1988-06-20 1988-07-27 Wellcome Found Medicaments
WO1990001334A1 (en) * 1988-08-05 1990-02-22 Codon Formulations for plasminogen activator using aspartate
GB8819607D0 (en) * 1988-08-17 1988-09-21 Wellcome Found Novel combination
US5714145A (en) * 1988-09-02 1998-02-03 Genentech, Inc. Tissue plasminogen activator having zymogenic or fibrin specific properties
US5262170A (en) * 1988-09-02 1993-11-16 Genentech, Inc. Tissue plasminogen activator having zymogenic or fibrin specific properties and substituted at amino acid positions 296-299, DNA molecules encoding them, vectors, and host cells
US4980165A (en) * 1989-01-27 1990-12-25 Genetics Institute, Inc. Pharmaceutical formulations of plasminogen activator proteins
DE3942142A1 (de) * 1989-12-20 1991-06-27 Boehringer Mannheim Gmbh Stabilisierung von glykosyliertem t-pa
GB9000629D0 (en) * 1990-01-11 1990-03-14 Porton Prod Ltd Tissue plasminogen activator
JP3559559B2 (ja) * 1992-06-03 2004-09-02 ジェネンテク，インコーポレイテッド 向上した治療特性を有する組織プラスミノーゲン活性化因子グリコシル化変異体
DK0827751T3 (da) * 1996-09-06 2003-03-31 Chemo Sero Therapeut Res Inst Medicinsk præparat indeholdende vævsplasminogenaktivator og nicotinamid
US6355243B1 (en) † 1999-11-13 2002-03-12 Bayer Corporation Method of thrombolysis by local delivery of active plasmin
US7544500B2 (en) 1999-11-13 2009-06-09 Talecris Biotherapeutics, Inc. Process for the production of a reversibly inactive acidified plasmin composition
EP1432437A2 (en) * 2001-09-07 2004-06-30 Global Biotech Inc. Human tissue urokinase type plasminogen activator formulation
KR20110017903A (ko) * 2008-06-04 2011-02-22 테일크리스 바이오쎄러퓨틱스 아이엔씨. 플라스민의 제조를 위한 조성물, 방법 및 키트
PL2403865T3 (pl) 2009-03-03 2016-01-29 Grifols Therapeutics Inc Sposoby wytwarzania plazminogenu

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3998947A (en) * 1973-11-30 1976-12-21 Pierre Fabre S.A. Process for obtaining a plasminogen activator
FR2252842B1 (da) * 1973-12-03 1977-11-04 Fabre Sa Pierre
DE3015699C2 (de) * 1979-04-26 1982-07-15 Asahi Kasei Kogyo K.K., Osaka Herstellung eines Plasminogen-Aktivators
CA1154671A (fr) * 1979-07-27 1983-10-04 Lucien D. D'hinterland Separation d'un activateur tissulaire du plasminogene
NL8003402A (nl) * 1980-06-11 1982-01-04 Leuven Res & Dev Vzw Nieuwe plasminogeen-activator en farmaceutisch preparaat met trombolytische werking.
ZA831399B (en) * 1982-03-05 1984-02-29 Health Lab Service Board New fibrinolytic enzymes and methods for their production and pharmaceutical compositions containing them
GR79202B (da) * 1982-05-05 1984-10-22 Genentech Inc
JPS5951220A (ja) * 1982-08-02 1984-03-24 Asahi Chem Ind Co Ltd 新規なプラスミノ−ゲン・アクチベ−タ−およびその製法ならびにこれを含有する薬剤
CH660742A5 (de) * 1982-10-29 1987-06-15 Mitsui Toatsu Chemicals Plasminogen-aktivator, verfahren zu seiner herstellung und diesen enthaltendes thrombolytisches agens.
AU554862B2 (en) * 1982-12-14 1986-09-04 Implico B.V. Plasminogen activator isolated by affinity chromatography
DE3382389D1 (de) * 1982-12-14 1991-10-02 South African Inventions Plasminogenaktivator.
JPS59196824A (ja) * 1983-04-21 1984-11-08 Kowa Co 吸着防止剤
EP0156169B1 (en) * 1984-02-29 1991-12-18 Asahi Kasei Kogyo Kabushiki Kaisha An aqueous solution of a tissue plasminogen activator dissolved therein at an increased concentration and a method
DE3439980A1 (de) * 1984-11-02 1986-05-07 Behringwerke Ag, 3550 Marburg Verfahren zur reinigung sowie pasteurisierung von urokinase
US4929444A (en) * 1985-05-28 1990-05-29 Burroughs Wellcome Co. Low pH pharmaceutical formulation containing t-PA
ZW14486A1 (en) * 1985-07-29 1986-10-22 Smithkline Beckman Corp Pharmaceutical dosage unit
JPH0672105B2 (ja) * 1985-10-02 1994-09-14 持田製薬株式会社 血栓溶解剤及びその製法
EP0417662B1 (de) * 1989-09-13 1995-12-13 Maschinenfabrik Rieter Ag Verfahren zum Starten eines Arbeitsablaufs eines Bedienungsautomaten an einer Textilmaschine

Also Published As

Publication number Publication date
ES8706443A1 (es) 1987-07-01
IT1191925B (it) 1988-03-31
CA1297008C (en) 1992-03-10
SE8602404L (sv) 1986-11-29
DE3617753C2 (da) 1988-06-30
GB8612781D0 (en) 1986-07-02
AU5796586A (en) 1986-12-04
NO862095L (no) 1986-12-01
ES555352A0 (es) 1987-07-01
SE8602404D0 (sv) 1986-05-27
FR2593393A1 (fr) 1987-07-31
GB2176703B (en) 1988-12-07
FR2593393B1 (fr) 1989-06-02
DK163174B (da) 1992-02-03
HUT42330A (en) 1987-07-28
GR861365B (en) 1986-09-29
DE3617753A1 (de) 1986-12-04
GB2176703A (en) 1987-01-07
SE462893B (sv) 1990-09-17
BE904831A (fr) 1986-11-27
LU86445A1 (fr) 1986-12-05
DK246886A (da) 1986-11-29
IL78937A0 (en) 1986-09-30
PT82647B (pt) 1989-01-30
ATA141186A (de) 1990-06-15
AU569429B2 (en) 1988-01-28
FI862226A (fi) 1986-11-29
DK163174C (da) 1992-06-22
AT391812B (de) 1990-12-10
CH664495A5 (de) 1988-03-15
NL8601354A (nl) 1986-12-16
NO171344C (no) 1993-03-03
NZ216306A (en) 1989-10-27
IT8648064A0 (it) 1986-05-27
HU200695B (en) 1990-08-28
NO171344B (no) 1992-11-23
FI85334C (fi) 1992-04-10
FI85334B (fi) 1991-12-31
FI862226A0 (fi) 1986-05-27
PT82647A (en) 1986-06-01
US5112609A (en) 1992-05-12
IL78937A (en) 1990-11-29

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Legal Events

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PBP Patent lapsed