DK2433968T3 - Dual targeting antibody of novel form and use thereof - Google Patents
Dual targeting antibody of novel form and use thereof Download PDFInfo
- Publication number
- DK2433968T3 DK2433968T3 DK09844974.7T DK09844974T DK2433968T3 DK 2433968 T3 DK2433968 T3 DK 2433968T3 DK 09844974 T DK09844974 T DK 09844974T DK 2433968 T3 DK2433968 T3 DK 2433968T3
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- antibody
- cancer
- dual targeting
- targeting antibody
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| AR085091A1 (es) | 2011-01-26 | 2013-09-11 | Kolltan Pharmaceuticals Inc | Anticuerpos anti-kit y sus usos |
| KR20120130658A (ko) * | 2011-05-23 | 2012-12-03 | 주식회사 파멥신 | 펩타이드가 융합된 이중표적항체 및 그 용도 |
| WO2013075740A1 (en) | 2011-11-23 | 2013-05-30 | Sanofi | Antibody purification method |
| LT2782598T (lt) | 2011-11-23 | 2020-07-27 | In3Bio Ltd. | Rekombinantiniai baltymai ir jų terapinis panaudojimas |
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| JP6144771B2 (ja) * | 2012-11-21 | 2017-06-07 | ファームアブシン インコーポレイテッド | Ｖｅｇｆｒ−２とｄｌｌ４を標的とする二重標的抗体及びこれを含む薬学的組成物 |
| WO2014108854A1 (en) | 2013-01-09 | 2014-07-17 | Fusimab Ltd. | Monospecific anti-hgf and anti-ang2 antibodies and bispecific anti-hgf/anti-ang2 antibodies |
| KR102049991B1 (ko) | 2013-03-28 | 2019-12-02 | 삼성전자주식회사 | 항 c-Met/항 Her2 이중 특이 항체 |
| KR102074421B1 (ko) | 2013-03-29 | 2020-02-10 | 삼성전자주식회사 | 항 c-Met/항 EGFR 이중 특이 항체 |
| KR102060540B1 (ko) | 2013-04-03 | 2019-12-31 | 삼성전자주식회사 | 항 c-Met 항체 및 항 Ang2 항체를 포함하는 병용 투여용 약학 조성물 |
| HUE038741T2 (hu) * | 2013-05-06 | 2018-11-28 | Sanofi Sa | Folyamatos többlépéses eljárás antitestek tisztítására |
| KR20150063728A (ko) * | 2013-12-02 | 2015-06-10 | 삼성전자주식회사 | 항 VEGF-C/항 Ang2 이중 특이 항체 |
| KR102223502B1 (ko) | 2014-05-09 | 2021-03-05 | 삼성전자주식회사 | 항 c-Met/항 EGFR/항 Her3 다중 특이 항체 및 이의 이용 |
| AR100271A1 (es) | 2014-05-19 | 2016-09-21 | Lilly Co Eli | Compuestos de vegfr2 / ang2 |
| CN106659782B (zh) | 2014-05-23 | 2021-11-09 | 塞尔德克斯医疗公司 | 一种用于嗜酸性粒细胞或肥大细胞相关病症治疗的抗体 |
| KR20160024639A (ko) | 2014-08-26 | 2016-03-07 | 삼성전자주식회사 | c-Met 표적 치료제의 저항성 또는 효능 예측을 위한 바이오마커 PDGF |
| WO2016060297A1 (ko) * | 2014-10-16 | 2016-04-21 | 주식회사 파멥신 | VEGFR-2 및 c-Met에 대하여 결합성을 갖는 이중표적항체 |
| KR102309881B1 (ko) | 2014-11-21 | 2021-10-06 | 삼성전자주식회사 | c-Met 및 EGFR의 이중 저해제 및 IGF-1R 저해제를 포함하는 병용 투여용 약학 조성물 |
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| KR102201992B1 (ko) * | 2016-09-08 | 2021-01-12 | 주식회사 우리기술 | clec14a에 특이적으로 결합하는 탈당화 항체 및 그 용도 |
| CN116836285A (zh) | 2017-03-09 | 2023-10-03 | 健玛保 | 针对pd-l1的抗体 |
| EP3601354A1 (en) | 2017-03-31 | 2020-02-05 | Genmab Holding B.V. | Bispecific anti-cd37 antibodies, monoclonal anti-cd37 antibodies and methods of use thereof |
| JP7290013B2 (ja) | 2017-08-04 | 2023-06-13 | ジェンマブ エー／エス | Ｐｄ－ｌ１およびｃｄ１３７に結合する結合物質ならびにその使用 |
| JP2021516702A (ja) * | 2018-03-19 | 2021-07-08 | ファームアブシン・インコーポレイテッドＰｈａｒｍａｂｃｉｎｅ Ｉｎｃ． | 抗−ｖｅｇｆｒ−２抗体 |
| EP3768313A4 (en) * | 2018-03-20 | 2022-01-05 | Yuh, Chiou Hwa | DUAL-FUNCTIONAL ANTIBODIES AGAINST VEGFR2 AND VEGFR3 DISHES |
| CN119881293A (zh) | 2018-03-21 | 2025-04-25 | 沃特世科技公司 | 基于非抗体高亲和力的样品制备、吸附剂、装置和方法 |
| EP3546475A1 (en) | 2018-03-27 | 2019-10-02 | Sanofi | Full flow-through process for purifying recombinant proteins |
| BR112021005184A8 (pt) | 2018-09-19 | 2022-08-16 | Lava Therapeutics B V | Imunoglobulina cd1d de dupla ação |
| MA53812A (fr) | 2018-10-04 | 2021-08-11 | Genmab Holding B V | Compositions pharmaceutiques comprenant des anticorps anti-cd37 bispécifiques |
| CN120983617A (zh) | 2018-11-06 | 2025-11-21 | 健玛保 | 抗体配制剂 |
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| CA3136975C (en) * | 2019-08-14 | 2024-06-25 | Pharmabcine Inc. | Anti-tie2 antibody and use thereof |
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| AU2021322046A1 (en) | 2020-08-06 | 2023-02-02 | BioNTech SE | Binding agents for coronavirus S protein |
| JP2023541860A (ja) | 2020-09-10 | 2023-10-04 | ジェンマブ エー／エス | びまん性大細胞型ｂ細胞リンパ腫を治療するための併用療法におけるｃｄ３及びｃｄ２０に対する二重特異性抗体 |
| CA3190349A1 (en) | 2020-09-10 | 2022-03-17 | Brian Elliott | Bispecific antibodies against cd3 and cd20 for treating chronic lymphocytic leukemia |
| JP2023545520A (ja) | 2020-10-14 | 2023-10-30 | ビリジアン セラピューティクス， インコーポレイテッド | 甲状腺眼疾患を治療するための組成物及び方法 |
| MX2023006832A (es) | 2020-12-10 | 2023-08-22 | Lava Therapeutics N V | Anticuerpos que se unen a receptores de linfocitos t gamma-delta. |
| EP4298125A1 (en) | 2021-02-26 | 2024-01-03 | LAVA Therapeutics N.V. | Antibodies that bind cd123 and gamma-delta t cell receptors |
| JP2024519212A (ja) | 2021-05-07 | 2024-05-09 | ジェンマブ エー／エス | Ｂ７ｈ４およびｃｄ３に結合する二重特異性抗体を含む薬学的組成物 |
| US20240262924A1 (en) | 2021-06-21 | 2024-08-08 | Genmab A/S | Combination dosage regime of cd137 and pd-l1 binding agents |
| WO2023019171A1 (en) | 2021-08-10 | 2023-02-16 | Viridian Therapeutics, Inc. | Compositions, doses, and methods for treatment of thyroid eye disease |
| AU2022344595A1 (en) | 2021-09-13 | 2024-05-02 | Janssen Biotech, Inc | CD33 X Vδ2 MULTISPECIFIC ANTIBODIES FOR THE TREATMENT OF CANCER |
| JP7503215B2 (ja) | 2021-10-08 | 2024-06-19 | ジェンマブ エー／エス | Ｃｄ３０及びｃｄ３に結合する抗体 |
| JP2024538958A (ja) | 2021-10-21 | 2024-10-28 | ラヴァ・セラピューティクス・エヌ・ヴイ | ガンマデルタｔ細胞活性化抗体の使用 |
| WO2023174521A1 (en) | 2022-03-15 | 2023-09-21 | Genmab A/S | Binding agents binding to epcam and cd137 |
| EP4285926A1 (en) | 2022-05-30 | 2023-12-06 | LAVA Therapeutics N.V. | Combination treatment for chronic lymphocytic leukemia |
| EP4292609A1 (en) | 2022-06-15 | 2023-12-20 | LAVA Therapeutics N.V. | Compositions comprising antibodies that bind gamma-delta t cell receptors |
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| NL2032398B1 (en) | 2022-07-06 | 2024-01-23 | Academisch Ziekenhuis Leiden | Bispecific antibody and uses thereof |
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| TW202506178A (zh) | 2023-04-05 | 2025-02-16 | 丹麥商珍美寶股份有限公司 | 包含與ｃｄ３０和ｃｄ３結合之抗體之醫藥組成物 |
| TW202509077A (zh) | 2023-06-30 | 2025-03-01 | 丹麥商珍美寶股份有限公司 | 與纖維母細胞活化蛋白α及死亡受體４結合之抗體 |
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| KR100272077B1 (ko) | 1990-08-29 | 2000-11-15 | 젠팜인터내셔날,인코포레이티드 | 이종 항체를 생산할 수 있는 전이유전자를 가진 인간이외의 동물 |
| US5661016A (en) | 1990-08-29 | 1997-08-26 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
| US5633425A (en) | 1990-08-29 | 1997-05-27 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
| WO1992009690A2 (en) | 1990-12-03 | 1992-06-11 | Genentech, Inc. | Enrichment method for variant proteins with altered binding properties |
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| CA2482607C (en) * | 2002-04-22 | 2013-06-11 | Fraunhofer-Gesellschaft Zur Foerderung Der Angewandten Forschung E.V. | Antibodies, recombinant antibodies, recombinant antibody fragments and fusions mediated plant disease resistance against fungi |
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| WO2006005361A1 (en) | 2004-07-13 | 2006-01-19 | Centre National De La Recherche Scientifique | Peptides liable to bind to the tie2 receptor, nucleic acids encoding them, and their uses |
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| CN1884300A (zh) * | 2005-06-24 | 2006-12-27 | 中国人民解放军军事医学科学院微生物流行病研究所 | 一种具有靶向功能的抗肝癌超抗原,其制备方法及用途 |
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| KR100883430B1 (ko) * | 2007-06-13 | 2009-02-12 | 한국생명공학연구원 | 혈관내피성장인자 수용체를 중화하는 인간 단클론항체 및그 용도 |
| KR102060540B1 (ko) * | 2013-04-03 | 2019-12-31 | 삼성전자주식회사 | 항 c-Met 항체 및 항 Ang2 항체를 포함하는 병용 투여용 약학 조성물 |
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- 2009-07-22 SG SG2011082542A patent/SG175971A1/en unknown
- 2009-07-22 WO PCT/KR2009/004084 patent/WO2010134666A1/ko not_active Ceased
- 2009-07-22 CN CN200980159382.XA patent/CN102428104B/zh not_active Expired - Fee Related
- 2009-07-22 RU RU2011146088/10A patent/RU2520824C2/ru active
- 2009-07-22 AU AU2009346447A patent/AU2009346447B2/en not_active Ceased
-
2014
- 2014-12-26 JP JP2014263739A patent/JP2015119705A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP5744012B2 (ja) | 2015-07-01 |
| EP2433968A4 (en) | 2012-12-05 |
| RU2520824C2 (ru) | 2014-06-27 |
| CA2762555C (en) | 2018-02-20 |
| ES2605604T3 (es) | 2017-03-15 |
| KR101224468B1 (ko) | 2013-01-23 |
| WO2010134666A1 (ko) | 2010-11-25 |
| EP2433968A1 (en) | 2012-03-28 |
| AU2009346447B2 (en) | 2013-11-14 |
| BRPI0924535A2 (pt) | 2015-06-30 |
| EP2433968B1 (en) | 2016-09-07 |
| CN102428104A (zh) | 2012-04-25 |
| US20120065380A1 (en) | 2012-03-15 |
| RU2011146088A (ru) | 2013-06-27 |
| JP2015119705A (ja) | 2015-07-02 |
| AU2009346447A1 (en) | 2011-12-01 |
| BRPI0924535B1 (pt) | 2021-07-20 |
| JP2012527234A (ja) | 2012-11-08 |
| US10125194B2 (en) | 2018-11-13 |
| KR20100125033A (ko) | 2010-11-30 |
| CN102428104B (zh) | 2015-03-04 |
| CA2762555A1 (en) | 2010-11-25 |
| SG175971A1 (en) | 2011-12-29 |
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