DK2414386T3 - Fuglevacciner med newcastle-sygdomsvirus-vektorer - Google Patents
Fuglevacciner med newcastle-sygdomsvirus-vektorer Download PDFInfo
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Claims (6)
1. Sammensætning omfattende (i) en genmanipuleret Newcastle-sygdomsvirus (NDV) -vektor og (ii) en farmaceutisk eller veterinær acceptabel bærer, excipiens eller vehikel; hvor den genmanipulerede NDV-vektor omfatter et polynukleotid med mindst 99% sekvensidentitet med et polynukleotid med sekvensen som vist i SEQ ID NO: 1 eller et polynukleotid komplementært med et polynukleotid med mindst 99% sekvensidentitet med polynukleotidet med sekvensen som vist i SEQ ID NO:l, og hvor den genmanipulerede NDV-vektor yderligere omfatter et heterologt polynukleotid der koder for et fugleinfluenza-hæmagglutin (HA)-antigen, og hvor HA-antigenet har mindst 80% aminosyresekvensidentitet med polypeptidet med sekvensen som vist i SEQ ID NO: 15, 17, 19, 21 eller 23.
2. Sammensætningen ifølge krav 1, hvor den genmanipulerede NDV-vektor omfatter et polynukleotid med sekvensen som vist i SEQ ID NO:l.
3. Sammensætningen ifølge krav 1, hvor det heterologe polynukleotid har mindst 80% sekvensidentitet med et polynukleotid med sekvensen som vist i SEQ ID NO: 14, 16, 18, 20 eller 22.
4. Sammensætningen ifølge krav 1, hvor HA-antigenet er et polypeptid med sekvensen som vist i SEQ ID NO: 15, 17, 19, 21 eller 23.
5. Sammensætning ifølge et hvilket som helst af kravene 1 til 4 til anvendelse i fremkaldelse af et beskyttelsesrespons hos en fugl eller vaccinere fuglen mod mindst ét fuglepatogen.
6. Anvendelse af sammensætningen ifølge et hvilket som helst af kravene 1 til 4 til fremstillingen af et medikament til fremkaldelse af et beskyttelsesrespons hos en fugl eller vaccinere fuglen mod mindst ét fuglepatogen.
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US16648109P | 2009-04-03 | 2009-04-03 | |
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DK10712667.4T DK2414386T3 (da) | 2009-04-03 | 2010-04-02 | Fuglevacciner med newcastle-sygdomsvirus-vektorer |
DK15159486.8T DK2998315T4 (da) | 2009-04-03 | 2010-04-02 | Newcastle sygdomsvirus-bårne fuglevacciner |
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DK15159486.8T DK2998315T4 (da) | 2009-04-03 | 2010-04-02 | Newcastle sygdomsvirus-bårne fuglevacciner |
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WO2010115133A3 (en) | 2011-01-06 |
MX347997B (es) | 2017-05-22 |
EP2414386A2 (en) | 2012-02-08 |
CN102428099B (zh) | 2016-03-16 |
JP2012522516A (ja) | 2012-09-27 |
CN102428099A (zh) | 2012-04-25 |
US8871220B2 (en) | 2014-10-28 |
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EP2998315A2 (en) | 2016-03-23 |
CN103585643A (zh) | 2014-02-19 |
US10350286B2 (en) | 2019-07-16 |
WO2010115133A8 (en) | 2012-01-19 |
JP5797636B2 (ja) | 2015-10-21 |
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CA2757030C (en) | 2019-01-15 |
US20100255029A1 (en) | 2010-10-07 |
CA2757030A1 (en) | 2010-10-07 |
DK2998315T3 (da) | 2019-01-28 |
EP2998315B1 (en) | 2018-10-31 |
WO2010115133A2 (en) | 2010-10-07 |
EP2414386B1 (en) | 2016-01-27 |
US20170224807A1 (en) | 2017-08-10 |
KR20120005486A (ko) | 2012-01-16 |
US20140234358A1 (en) | 2014-08-21 |
EP2998315B2 (en) | 2021-11-03 |
DK2998315T4 (da) | 2022-02-07 |
KR101715418B1 (ko) | 2017-03-10 |
MX2011010406A (es) | 2012-01-20 |
JP2015232022A (ja) | 2015-12-24 |
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