DK2270172T3 - Kombinationssammensætninger af Neisseria. - Google Patents

Kombinationssammensætninger af Neisseria. Download PDF

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Publication number
DK2270172T3
DK2270172T3 DK10178238.1T DK10178238T DK2270172T3 DK 2270172 T3 DK2270172 T3 DK 2270172T3 DK 10178238 T DK10178238 T DK 10178238T DK 2270172 T3 DK2270172 T3 DK 2270172T3
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DK
Denmark
Prior art keywords
seq
nos
sequence
amino acid
proteins
Prior art date
Application number
DK10178238.1T
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English (en)
Inventor
Marzia Monica Giuliani
Mariagrazia Pizza
Rino Rappuoli
Original Assignee
Glaxosmithkline Biolog Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9911692.3A external-priority patent/GB9911692D0/en
Priority claimed from GBGB9919705.5A external-priority patent/GB9919705D0/en
Priority claimed from GB0005730A external-priority patent/GB0005730D0/en
Application filed by Glaxosmithkline Biolog Sa filed Critical Glaxosmithkline Biolog Sa
Application granted granted Critical
Publication of DK2270172T3 publication Critical patent/DK2270172T3/da

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)

Claims (2)

1. Sammensætning omfattende to eller flere forskellige Neisseria-proteiner, hvor de to eller flere forskellige Neisseria-proteiner omfatter et første protein fra en Neisseria-bakterie og et andet protein fra en Neisseria-bakterie, og hvor (i) det første protein omfatter en aminosyresekvens valgt blandt (a) SEQ ID NO: 2182; (b) en sekvens, der har større end 80% sekvensidentitet med SEQ ID NO: 2182; og det andet protein omfatter en aminosyresekvens valgt blandt (a) én af de lige SEQ ID NOs valgt blandt SEQ ID NOs: 1-2181 og 2183-4002; (b) en sekvens, der har større end 80% sekvensidentitet med én af de lige SEQ ID NOs valgt blandt SEQ ID NOs: 1-2181 og 2183-4002; eller (ii) det første protein omfatter en aminosyresekvens valgt blandt (a) SEQ ID NO: 2184; (b) en sekvens, der har større end 80% sekvensidentitet SEQ ID NO: 2184; og det andet protein omfatter en aminosyresekvens valgt blandt (a) én af de lige SEQ ID NOs valgt blandt SEQ ID NOs: 1-2183 og 2185-4002; (b) en sekvens, der har større end 80% sekvensidentitet med én af de lige SEQ ID NOs valgt blandt SEQ ID NOs: 1-2183 og 2185-4002; eller (iii) det første protein omfatter en aminosyresekvens valgt blandt (a) SEQ ID NO: 2186; (b) en sekvens, der har større end 80% sekvensidentitet med SEQ ID NO: 2186; og det andet protein omfatter en aminosyresekvens valgt blandt (a) én af de lige SEQ ID NOs valgt blandt SEQ ID NOs: 1-2185 og 2187-4002; (b) en sekvens, der har større end 80% sekvensidentitet med én af de lige SEQ ID NOs valgt blandt SEQ ID NOs: 1-2185 og 2187-4002.
2. Sammensætning ifølge krav 1, omfattende to eller flere oprensede proteiner valgt blandt de lige SEQ IDs 1-4002.
DK10178238.1T 1999-05-19 2000-05-19 Kombinationssammensætninger af Neisseria. DK2270172T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB9911692.3A GB9911692D0 (en) 1999-05-19 1999-05-19 Antigenic combinations
GBGB9919705.5A GB9919705D0 (en) 1999-08-19 1999-08-19 Antigenic combinations
GB0005730A GB0005730D0 (en) 2000-03-09 2000-03-09 Antigenic combinations
EP07075627A EP1860191A3 (en) 1999-05-19 2000-05-19 Combination neisserial compositions

Publications (1)

Publication Number Publication Date
DK2270172T3 true DK2270172T3 (da) 2016-02-29

Family

ID=27255587

Family Applications (2)

Application Number Title Priority Date Filing Date
DK10179061.6T DK2270173T3 (da) 1999-05-19 2000-05-19 Neisseriale kombinationssammensætninger
DK10178238.1T DK2270172T3 (da) 1999-05-19 2000-05-19 Kombinationssammensætninger af Neisseria.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK10179061.6T DK2270173T3 (da) 1999-05-19 2000-05-19 Neisseriale kombinationssammensætninger

Country Status (14)

Country Link
US (9) US7862827B2 (da)
EP (6) EP2258851A1 (da)
JP (3) JP5622344B2 (da)
CN (2) CN100338218C (da)
AU (3) AU783894B2 (da)
BR (1) BR0010721A (da)
CA (3) CA2373236C (da)
CY (2) CY1117235T1 (da)
DK (2) DK2270173T3 (da)
ES (2) ES2563677T3 (da)
MX (1) MXPA01011867A (da)
NZ (4) NZ545647A (da)
PT (2) PT2270173E (da)
WO (1) WO2000071725A2 (da)

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