DK2212289T3 - Fremgangsmåde til fremstilling af 2,2-difluorethylamin-derivater ved hjælp af amid-hydrering - Google Patents

Fremgangsmåde til fremstilling af 2,2-difluorethylamin-derivater ved hjælp af amid-hydrering

Info

Publication number
DK2212289T3
DK2212289T3 DK08785831.2T DK08785831T DK2212289T3 DK 2212289 T3 DK2212289 T3 DK 2212289T3 DK 08785831 T DK08785831 T DK 08785831T DK 2212289 T3 DK2212289 T3 DK 2212289T3
Authority
DK
Denmark
Prior art keywords
difluorethylamine
amid
hydration
derivatives
preparing
Prior art date
Application number
DK08785831.2T
Other languages
English (en)
Inventor
Norbert Lui
Stefan Antons
Original Assignee
Bayer Cropscience Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Cropscience Ag filed Critical Bayer Cropscience Ag
Application granted granted Critical
Publication of DK2212289T3 publication Critical patent/DK2212289T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61Halogen atoms or nitro radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B61/00Other general methods
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/44Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers
    • C07C209/50Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers by reduction of carboxylic acid amides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DK08785831.2T 2007-09-18 2008-09-05 Fremgangsmåde til fremstilling af 2,2-difluorethylamin-derivater ved hjælp af amid-hydrering DK2212289T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07116640 2007-09-18
PCT/EP2008/007271 WO2009036900A1 (de) 2007-09-18 2008-09-05 Verfahren zur herstellung von 2,2-difluorethylamin-derivaten durch amid-hydrierung

Publications (1)

Publication Number Publication Date
DK2212289T3 true DK2212289T3 (da) 2014-01-27

Family

ID=40227973

Family Applications (1)

Application Number Title Priority Date Filing Date
DK08785831.2T DK2212289T3 (da) 2007-09-18 2008-09-05 Fremgangsmåde til fremstilling af 2,2-difluorethylamin-derivater ved hjælp af amid-hydrering

Country Status (12)

Country Link
US (1) US8273897B2 (da)
EP (1) EP2212289B1 (da)
JP (1) JP5329547B2 (da)
KR (1) KR101565391B1 (da)
CN (1) CN101801929B (da)
BR (1) BRPI0816830B1 (da)
DK (1) DK2212289T3 (da)
ES (1) ES2438568T3 (da)
IL (1) IL203843A (da)
MX (1) MX2010001961A (da)
TW (1) TWI406848B (da)
WO (1) WO2009036900A1 (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2509937B1 (de) * 2009-12-11 2014-10-08 Bayer Intellectual Property GmbH Verfahren zur herstellung von 2,2-difluorethylamin sowie seiner salze ausgehend von difluoracetonitril
CN103003241B (zh) * 2010-06-15 2014-07-30 拜耳知识产权有限责任公司 通过用2,2-二氟乙基-1-卤代乙烷烷基化制备2,2-二氟乙胺衍生物的方法
EP2638010B1 (de) * 2010-11-12 2014-12-31 Bayer Intellectual Property GmbH Verfahren zur herstellung von 2,2-difluorethylamin-derivaten ausgehend von n-(2,2-difluorethyl)prop-2-en-1-amin
KR20150032537A (ko) 2012-06-29 2015-03-26 바이엘 크롭사이언스 아게 2,2-디플루오로에틸아민의 알킬화에 의한 2,2-디플루오로에틸아민 유도체의 제조 방법
BR112016021564B1 (pt) 2014-03-21 2021-03-23 Bayer Cropscience Aktiengesellschaft Método para a preparação de n-[(6-cloropiridin-3-il)metil]-2,2-difluoroetano-1-amina pela alquilação de 2,2-difluoroetilamina
CN111892601B (zh) * 2020-09-01 2023-09-26 陕西大美化工科技有限公司 一种吡啶并吡唑并噌啉类化合物及其制备方法与应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2691043A (en) * 1950-03-13 1954-10-05 Minnesota Mining & Mfg Fluorinated amines
JP3632243B2 (ja) 1994-07-28 2005-03-23 旭硝子株式会社 ジフルオロ酢酸フルオリドおよびジフルオロ酢酸エステルの製造方法
JP2007284352A (ja) 2004-08-05 2007-11-01 Dai Ichi Seiyaku Co Ltd ピラゾール誘導体
ES2402362T3 (es) * 2004-09-30 2013-05-03 Takeda Pharmaceutical Company Limited Inhibidores de la bomba de protones
DE102006015467A1 (de) * 2006-03-31 2007-10-04 Bayer Cropscience Ag Substituierte Enaminocarbonylverbindungen
DE102006015468A1 (de) * 2006-03-31 2007-10-04 Bayer Cropscience Ag Substituierte Enaminocarbonylverbindungen
DE102006033572A1 (de) * 2006-07-20 2008-01-24 Bayer Cropscience Ag N'-Cyano-N-halogenalkyl-imidamid Derivate

Also Published As

Publication number Publication date
TWI406848B (zh) 2013-09-01
JP2010539201A (ja) 2010-12-16
WO2009036900A1 (de) 2009-03-26
KR101565391B1 (ko) 2015-11-03
EP2212289A1 (de) 2010-08-04
BRPI0816830B1 (pt) 2016-05-17
IL203843A (en) 2014-02-27
CN101801929B (zh) 2013-10-09
JP5329547B2 (ja) 2013-10-30
US8273897B2 (en) 2012-09-25
EP2212289B1 (de) 2013-10-23
BRPI0816830A2 (pt) 2015-03-10
CN101801929A (zh) 2010-08-11
MX2010001961A (es) 2010-03-10
KR20100061827A (ko) 2010-06-09
US20100222593A1 (en) 2010-09-02
ES2438568T3 (es) 2014-01-17
BRPI0816830A8 (pt) 2015-10-27
TW200922924A (en) 2009-06-01

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