DK2129237T3 - Compositions and methods for promoting bone development - Google Patents
Compositions and methods for promoting bone development Download PDFInfo
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- DK2129237T3 DK2129237T3 DK08730572.8T DK08730572T DK2129237T3 DK 2129237 T3 DK2129237 T3 DK 2129237T3 DK 08730572 T DK08730572 T DK 08730572T DK 2129237 T3 DK2129237 T3 DK 2129237T3
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Classifications
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Landscapes
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| US89117107P | 2007-02-22 | 2007-02-22 | |
| PCT/US2008/054796 WO2008103956A1 (en) | 2007-02-22 | 2008-02-22 | Compositions and methods for promoting bone development |
Publications (1)
| Publication Number | Publication Date |
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| DK2129237T3 true DK2129237T3 (en) | 2015-09-14 |
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| DK08730572.8T DK2129237T3 (en) | 2007-02-22 | 2008-02-22 | Compositions and methods for promoting bone development |
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| EP (5) | EP2112889B1 (cg-RX-API-DMAC7.html) |
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| PL1937721T3 (pl) * | 2005-08-25 | 2010-12-31 | Lilly Co Eli | Przeciwciała anty-IL23 |
| US20100143497A1 (en) | 2007-02-22 | 2010-06-10 | Hill's Pet Nutrition, Inc. | Compositions and Methods For Promoting Bone Development |
| EP2367547B1 (en) * | 2008-12-12 | 2014-07-30 | Cognite AB | L-lysine for improving normal cognitive functions |
| CA2785646C (en) | 2009-12-29 | 2016-10-18 | Hill's Pet Nutrition, Inc. | Compositions including ginger for the amelioration or prevention of inflammatory conditions |
| US20130059012A1 (en) * | 2010-05-12 | 2013-03-07 | Hill's Pet Nutrition, Inc | Methods for the Diagnosis, Control and Prophylaxis of Inflammation and Mitigation of Inflammatory Conditions in Felines |
| CA2821489A1 (en) * | 2010-12-20 | 2012-06-28 | Hill's Pet Nutrition, Inc. | Pet food compositions for inducing a satiety response |
| EP2705844B1 (en) * | 2011-04-13 | 2019-05-22 | Ajinomoto Co., Inc. | Nutritional composition |
| US8828426B2 (en) | 2011-06-07 | 2014-09-09 | Zx Pharma, Llc | Multiparticulate L-carnitine compositions and related methods |
| WO2013095935A1 (en) | 2011-12-19 | 2013-06-27 | Hill's Pet Nutrition, Inc. | Compositions and methods for diagnosing and treating hyperthyroidism in companion animals |
| CN103315187B (zh) * | 2013-07-17 | 2014-11-05 | 江苏桂龙生物技术有限公司 | 一种预防宠物骨骼性疾病的饲料 |
| CN104026401B (zh) * | 2014-06-10 | 2016-04-27 | 务川县绿之源农业技术推广中心 | 一种小型幼犬粮 |
| US20170360737A1 (en) * | 2014-10-30 | 2017-12-21 | Fuji Oil Holdings Inc. | Long-chain polyunsaturated fatty-acid-containing fat and food containing same |
| GB201522300D0 (en) * | 2015-12-17 | 2016-02-03 | Mars Inc | Puppy growth food product |
| AU2017376984B2 (en) | 2016-12-15 | 2021-12-23 | Société des Produits Nestlé S.A. | Compositions and methods for small canines |
| US11617737B2 (en) | 2016-12-15 | 2023-04-04 | Société des Produits Nestlé S.A. | Compositions and methods that modulate vitamin D and bone mineral content in a companion animal |
| CN110678175A (zh) * | 2017-05-29 | 2020-01-10 | 雀巢产品有限公司 | 用于预防或治疗心脏增大和/或瓣膜性心脏病的中链脂肪酸 |
| WO2019155336A1 (en) * | 2018-02-08 | 2019-08-15 | Societe Des Produits Nestle S.A. | Mct-based nutrition blend for providing health benefits in companion animals |
| CN108244374A (zh) * | 2018-02-27 | 2018-07-06 | 佛山市雷米高动物营养保健科技有限公司 | 猫用营养粉剂及其制备方法 |
| JP7391977B2 (ja) * | 2019-02-01 | 2023-12-05 | マース インコーポレーテッド | ネコ科動物用飼料組成物 |
| CN110537630A (zh) * | 2019-09-09 | 2019-12-06 | 天津农学院 | 1，2二硫戊环-3-戊酸的应用、幼犬鲜粮和延长幼犬鲜粮贮藏期的方法 |
| MX2022006412A (es) * | 2019-12-19 | 2022-08-02 | Nestle Sa | Composiciones y metodos para proporcionar un beneficio de salud a un animal en crecimiento. |
| US20230165281A1 (en) * | 2021-11-29 | 2023-06-01 | Société des Produits Nestlé S.A. | Methods and compositions for providing a health benefit in an animal |
| WO2023150389A1 (en) * | 2022-02-07 | 2023-08-10 | Cornell University | Compositions and methods for increasing dha availability |
Family Cites Families (33)
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|---|---|---|---|---|
| US4267195A (en) * | 1976-09-10 | 1981-05-12 | University Of Texas | Dog food flavors |
| US4130651A (en) * | 1978-03-31 | 1978-12-19 | American Cyanamid Company | Butamisole injectable formulations having improved margin of safety in dogs |
| JPH0625057B2 (ja) | 1987-12-14 | 1994-04-06 | 日本油脂株式会社 | 骨形成促進剤 |
| JPH04166039A (ja) * | 1990-10-26 | 1992-06-11 | Hirotoshi Yokura | ペットフード |
| US5690988A (en) * | 1996-02-02 | 1997-11-25 | Colgate Palmolive Company | Pet food composition of improved palatability and a method of enhancing the palatability of a food composition |
| US5851573A (en) * | 1997-04-29 | 1998-12-22 | The Iams Company | Pet food composition for large breed puppies and method for promoting proper skeletal growth |
| US6156355A (en) * | 1998-11-02 | 2000-12-05 | Star-Kist Foods, Inc. | Breed-specific canine food formulations |
| NZ527924A (en) | 1999-01-29 | 2005-01-28 | Mars Uk Ltd | Antioxidant compositions and methods for companion animals |
| GB2367489B (en) * | 2000-07-31 | 2005-02-09 | Mars Inc | Use of antioxidants |
| US6071544A (en) * | 1999-04-01 | 2000-06-06 | The Iams Company | Dietary compositions and method for promoting healthy weight loss cats |
| MXPA01010940A (es) | 1999-05-27 | 2002-07-30 | Iams Company | Proceso y producto para mejorar la respuesta inmunitlaria en animales de compania, usando una combinacion de antioxidantes. |
| EG22407A (en) * | 2000-02-17 | 2003-01-29 | Iams Company | Method for improving bone modeling and chondrocyte functioning in growing canines |
| GB2367487A (en) | 2000-10-04 | 2002-04-10 | John Kennedy Mcmillan | Tooth cleaner |
| EP1345500B1 (en) | 2000-12-29 | 2008-07-30 | Martin Francis Gannon | An animal food product |
| US6582752B2 (en) | 2001-11-02 | 2003-06-24 | Nestec, Ltd | Methods and compositions for a gender specific diet for puppies |
| AU2003248869A1 (en) | 2002-07-12 | 2004-02-02 | The Iams Company | Synergistic effect of diet and human interaction on the behavior of dogs |
| JPWO2004008196A1 (ja) * | 2002-07-13 | 2005-11-10 | 有限会社オートクローニング・テクノロジー | 偏光解析装置 |
| AU2003254544A1 (en) | 2002-07-26 | 2004-02-23 | Dsm Ip Assets B.V. | Compositions comprising lactoferrin |
| EP1619960A4 (en) | 2003-03-07 | 2009-03-18 | Advanced Bionutrition Corp | FEED FORMULATION FOR LAND AND WATER RESIDENTS |
| WO2004095940A1 (en) * | 2003-04-25 | 2004-11-11 | The University Of Newcastle | Biomass containing animal feed |
| WO2005006877A1 (en) * | 2003-07-03 | 2005-01-27 | Hill's Pet Nutrition, Inc. | Compositions and methods for decreasing age-related deterioration in metal activities in companion animals |
| BRPI0412332A (pt) | 2003-07-07 | 2006-09-05 | Hills Pet Nutrition Inc | método para aumentar nìveis de antioxidante no sangue em um felino, e, composição para dieta adequada para alimentar animais de companhia jovens |
| AU2004210599B2 (en) | 2003-09-12 | 2009-09-24 | Mars, Incorporated | Food product for hairball treatment |
| US8921422B2 (en) * | 2003-10-01 | 2014-12-30 | The Iams Company | Methods and kits for enhancing ability to learn in a puppy or kitten |
| US20050266051A1 (en) * | 2004-05-27 | 2005-12-01 | The Procter & Gamble Company | Pet food compositions and methods |
| CA2578634C (en) * | 2004-08-30 | 2016-06-14 | Hill's Pet Nutrition, Inc. | Genome-based diet design |
| CN1631207A (zh) | 2004-12-03 | 2005-06-29 | 王志文 | 能改善猫狗皮毛质量的不饱和脂肪酸饲料添加剂及饲料 |
| EP2762007B1 (en) | 2004-12-30 | 2016-11-02 | Hill's Pet Nutrition, Inc. | Methods for enhancing the quality of life of a growing animal |
| BRPI0519610A2 (pt) * | 2004-12-30 | 2009-02-25 | Hills Pet Nutrition Inc | mÉtodos para melhorar a qualidade de vida de um animal idoso ou muito idoso, de um canino de raÇa regular ou pequena, idoso ou muito idoso, de um cço de raÇa grande idoso ou muito idoso, e de um gato idoso ou muito idoso |
| RU2413427C2 (ru) | 2005-09-30 | 2011-03-10 | Нестек С.А. | Способы и композиция для улучшения когнитивной функции |
| CN103445019A (zh) * | 2006-01-10 | 2013-12-18 | 希尔氏宠物营养品公司 | 用于促进脂肪减少的组合物和方法 |
| US20080076823A1 (en) | 2006-08-09 | 2008-03-27 | Watkins Bruce A | Methods of improving bone health and muscle health |
| US20100143497A1 (en) * | 2007-02-22 | 2010-06-10 | Hill's Pet Nutrition, Inc. | Compositions and Methods For Promoting Bone Development |
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