DK20682A - Fremgangsmaade til fremstilling af et pyrrolidinderivat - Google Patents

Fremgangsmaade til fremstilling af et pyrrolidinderivat Download PDF

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Publication number
DK20682A
DK20682A DK20682A DK20682A DK20682A DK 20682 A DK20682 A DK 20682A DK 20682 A DK20682 A DK 20682A DK 20682 A DK20682 A DK 20682A DK 20682 A DK20682 A DK 20682A
Authority
DK
Denmark
Prior art keywords
pyrrolide
derivative
preparing
procedure
pyrrolide derivative
Prior art date
Application number
DK20682A
Other languages
Danish (da)
English (en)
Inventor
W Aschwanden
E Kyburz
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of DK20682A publication Critical patent/DK20682A/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24Oxygen or sulfur atoms
    • C07D207/262-Pyrrolidones
    • C07D207/2732-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/10Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DK20682A 1981-02-05 1982-01-18 Fremgangsmaade til fremstilling af et pyrrolidinderivat DK20682A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH77081A CH646149A5 (de) 1981-02-05 1981-02-05 Pyrrolidin-derivat.

Publications (1)

Publication Number Publication Date
DK20682A true DK20682A (da) 1982-08-06

Family

ID=4194769

Family Applications (1)

Application Number Title Priority Date Filing Date
DK20682A DK20682A (da) 1981-02-05 1982-01-18 Fremgangsmaade til fremstilling af et pyrrolidinderivat

Country Status (40)

Country Link
US (1) US4452807A (fr)
EP (1) EP0057846B1 (fr)
JP (1) JPS57146753A (fr)
KR (1) KR830009023A (fr)
AR (1) AR231127A1 (fr)
AT (2) ATE13668T1 (fr)
AU (1) AU552063B2 (fr)
BG (1) BG36932A3 (fr)
BR (1) BR8200615A (fr)
CA (1) CA1158250A (fr)
CH (1) CH646149A5 (fr)
CS (1) CS227035B2 (fr)
DD (1) DD202539A5 (fr)
DE (2) DE3263960D1 (fr)
DK (1) DK20682A (fr)
ES (1) ES509312A0 (fr)
FI (1) FI820192L (fr)
FR (1) FR2499075A1 (fr)
GB (1) GB2092584B (fr)
GR (1) GR76052B (fr)
HU (1) HU184988B (fr)
IE (1) IE52439B1 (fr)
IL (1) IL64896A (fr)
IS (1) IS2700A7 (fr)
IT (1) IT1153402B (fr)
LU (1) LU83923A1 (fr)
MC (1) MC1440A1 (fr)
NL (1) NL8200337A (fr)
NO (1) NO820346L (fr)
NZ (1) NZ199624A (fr)
OA (1) OA07002A (fr)
PH (1) PH18267A (fr)
PL (1) PL135221B1 (fr)
PT (1) PT74387B (fr)
RO (1) RO83099B (fr)
SE (1) SE8200647L (fr)
SU (1) SU1143315A3 (fr)
YU (1) YU23982A (fr)
ZA (1) ZA82608B (fr)
ZW (1) ZW1982A1 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2515179A1 (fr) * 1981-07-24 1983-04-29 Hoffmann La Roche Derives de pyrrolidine, leur procede de preparation, les intermediaires pour leur synthese et leur application therapeutique
FR2551751B1 (fr) * 1983-09-12 1986-04-25 Serobiologiques Lab Sa Nouveau procede de preparation d'un derive pyroglutamique, nouveaux derives pyroglutamiques, nouveaux intermediaires de synthese de preparation de ceux-ci et utilisation ou application des derives pyroglutamiques comme agents antibacteriens ou antifongiques
DE3336024A1 (de) * 1983-10-04 1985-04-18 Boehringer Ingelheim KG, 6507 Ingelheim 4-amino-l-benzyl-pyrrolidinone und ihre saeureadditionssalze, verfahren zu ihrer herstellung und arzneimittel
DE3537075A1 (de) * 1985-10-18 1987-04-23 Bayer Ag Verfahren zur herstellung von clausenamid
DE3632589A1 (de) * 1985-10-18 1987-04-23 Bayer Ag Verfahren zur herstellung von (gamma)-butyrolactamen
US4677114A (en) * 1985-11-22 1987-06-30 Warner-Lambert Company Pyrrolidone-2 derivatives and pharmaceutical compositions thereof
IT1215587B (it) * 1987-06-26 1990-02-14 Roussel Maestretti Spa Derivati della 1-benzoil2-oxo 5-alcossi pirrolidina, loro procedimento di preparazione e loro impiego come sostanza medicinale.
JPH0720930B2 (ja) * 1988-07-09 1995-03-08 明治製菓株式会社 ピロリジノン化合物及び脳機能障害改善剤
US5049577A (en) * 1990-01-29 1991-09-17 E. R. Squibb & Sons, Inc. 2-pyrrolidone substituted dihydroxy alkanoic, alkenoic and alkynoic acids, compositions and HMG-CoA reductase inhibition therewith
US5049578A (en) * 1990-03-09 1991-09-17 E. R. Squibb & Sons, Inc. 1-aroyl or 1-acyl-2-2pyrrolidinyl-3,5-dihydroxy alkanoic and alkenoic acids, salts, esters and lactones
DE69331761T2 (de) * 1992-07-24 2002-09-12 The Regents Of The University Of California, Oakland Arzneimittel, die den durch ampa rezeptoren vermittelten synaptischen respons erhöhen
US5852008A (en) * 1995-01-24 1998-12-22 The Regents Of The University Of California Heteroatom substituted benzoyl derivatives that enhance synaptic response mediated by receptors

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES433723A1 (es) * 1975-01-10 1976-11-16 Lafarquim S A Lab Procedimiento de obtencion de un derivado de 2-pirrolidi- nona.
IT1045043B (it) * 1975-08-13 1980-04-21 Isf Spa Derivati pirrolidinici
CU21107A3 (es) * 1978-02-10 1988-02-01 Hoffmann La Roche Pyrrolidines derivatives
CA1115212A (fr) * 1978-02-10 1981-12-29 Emilio Kyburz Derives de pyrrolidine
IT1131959B (it) * 1979-08-09 1986-06-25 Hoffmann La Roche Derivati pirrolidinici

Also Published As

Publication number Publication date
EP0057846B1 (fr) 1985-06-05
RO83099A (fr) 1984-02-21
IL64896A (en) 1985-07-31
CA1158250A (fr) 1983-12-06
PH18267A (en) 1985-05-14
AU8010482A (en) 1982-08-12
NL8200337A (nl) 1982-09-01
ZA82608B (en) 1982-12-29
PL135221B1 (en) 1985-10-31
ATA41882A (de) 1984-10-15
IE52439B1 (en) 1987-10-28
AT377982B (de) 1985-05-28
BR8200615A (pt) 1982-12-14
GR76052B (fr) 1984-08-03
ES8304545A1 (es) 1983-03-16
JPS57146753A (en) 1982-09-10
ATE13668T1 (de) 1985-06-15
LU83923A1 (de) 1983-09-02
PT74387B (en) 1984-10-22
OA07002A (fr) 1983-08-31
CH646149A5 (de) 1984-11-15
YU23982A (en) 1985-03-20
GB2092584B (en) 1984-08-01
PL234962A1 (fr) 1982-09-27
AU552063B2 (en) 1986-05-22
NO820346L (no) 1982-08-06
FR2499075A1 (fr) 1982-08-06
NZ199624A (en) 1984-12-14
RO83099B (ro) 1984-02-28
CS227035B2 (en) 1984-04-16
IL64896A0 (en) 1982-03-31
SE8200647L (sv) 1982-08-06
FI820192L (fi) 1982-08-06
IT8219115A0 (it) 1982-01-14
IT1153402B (it) 1987-01-14
PT74387A (en) 1982-03-01
HU184988B (en) 1984-11-28
IS2700A7 (is) 1982-08-06
DE3202281A1 (de) 1982-09-16
AR231127A1 (es) 1984-09-28
MC1440A1 (fr) 1982-12-06
ES509312A0 (es) 1983-03-16
KR830009023A (ko) 1983-12-17
US4452807A (en) 1984-06-05
ZW1982A1 (en) 1982-09-01
DE3263960D1 (en) 1985-07-11
IE820249L (en) 1982-08-05
EP0057846A1 (fr) 1982-08-18
BG36932A3 (en) 1985-02-15
DD202539A5 (de) 1983-09-21
GB2092584A (en) 1982-08-18
SU1143315A3 (ru) 1985-02-28
JPH0354097B2 (fr) 1991-08-19

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment
AHB Application shelved due to non-payment