DK198182A - 1,5-substituerede isoquinolinderivater og fremgangsmaade til fremstilling deraf - Google Patents

1,5-substituerede isoquinolinderivater og fremgangsmaade til fremstilling deraf Download PDF

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Publication number
DK198182A
DK198182A DK198182A DK198182A DK198182A DK 198182 A DK198182 A DK 198182A DK 198182 A DK198182 A DK 198182A DK 198182 A DK198182 A DK 198182A DK 198182 A DK198182 A DK 198182A
Authority
DK
Denmark
Prior art keywords
procedures
preparing
isoquinoline derivatives
substituted isoquinoline
substituted
Prior art date
Application number
DK198182A
Other languages
Danish (da)
English (en)
Inventor
H S Lowrie
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Publication of DK198182A publication Critical patent/DK198182A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • C07D263/24—Oxygen atoms attached in position 2 with hydrocarbon radicals, substituted by oxygen atoms, attached to other ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK198182A 1981-05-04 1982-05-03 1,5-substituerede isoquinolinderivater og fremgangsmaade til fremstilling deraf DK198182A (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US26054781A 1981-05-04 1981-05-04
US26054781 1981-05-04
US06/329,789 US4473501A (en) 1981-05-04 1981-12-11 Dihydro azino isoquinolines
US32978981 1981-12-11

Publications (1)

Publication Number Publication Date
DK198182A true DK198182A (da) 1982-11-05

Family

ID=26948062

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198182A DK198182A (da) 1981-05-04 1982-05-03 1,5-substituerede isoquinolinderivater og fremgangsmaade til fremstilling deraf

Country Status (7)

Country Link
US (1) US4473501A (de)
EP (1) EP0064294A1 (de)
AU (1) AU8321782A (de)
DK (1) DK198182A (de)
ES (1) ES8401066A1 (de)
NO (1) NO821458L (de)
PT (1) PT74838B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60237070A (ja) * 1984-05-08 1985-11-25 Nisshin Flour Milling Co Ltd 光学活性イソカルボスチリル誘導体の製法
SE8801518D0 (sv) * 1988-04-22 1988-04-22 Astra Pharma Prod A novel process
TW575567B (en) 1998-10-23 2004-02-11 Akzo Nobel Nv Serine protease inhibitor
WO2003106413A2 (en) * 2001-10-18 2003-12-24 Michigan State University Process for the preparation of oxazolidinones and method of use thereof
US7094789B2 (en) * 2002-07-22 2006-08-22 Asahi Kasei Pharma Corporation 5-substituted isoquinoline derivatives
EP2141154A4 (de) 2007-03-30 2011-06-01 Inst Med Molecular Design Inc Oxazolidinonderivat mit hemmender wirkung auf die 11-hydroxysteroiddehydrogenase vom typ i

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA536744A (en) * 1957-02-05 Druey Jean Isoquinoline compounds and process of making same
CH307873A (de) * 1952-05-30 1955-06-15 Ciba Geigy Verfahren zur Herstellung einer neuen Isochinolinverbindung.
GB1058822A (en) * 1963-07-30 1967-02-15 Ici Ltd 3-amino-2-hydroxypropoxy heterocyclic derivatives
US4009170A (en) * 1970-08-10 1977-02-22 Sterling Drug Inc. 1-Ethoxy-3,4-dihydroisoquindines
US3753994A (en) * 1970-08-10 1973-08-21 Sterling Drug Inc 1,1'-azinobis(1,2,3,4-tetrahydroisoquinolines)
US3946009A (en) * 1972-05-05 1976-03-23 Merck Sharp & Dohme (I.A.) Corporation 2-(3-Substituted amino-2-hydroxypropoxy)-3-substituted pyrazines
US4115575A (en) * 1973-02-20 1978-09-19 Ciba-Geigy Corporation 2-(3-Amino-2-hydroxy-propoxy)-pyrazines
US4073909A (en) * 1973-10-08 1978-02-14 Sandoz Ltd. Isoquinoline compounds
SE431451B (sv) * 1973-10-24 1984-02-06 Otsuka Pharma Co Ltd Forfarande for framstellning av 2,3-dihydroxipropoxikinoliner eller -isokinoliner
JPS538707B2 (de) * 1974-02-05 1978-03-31
JPS5318032B2 (de) * 1974-03-04 1978-06-13
DE2639718C2 (de) * 1976-09-03 1987-03-05 Dr. Karl Thomae Gmbh, 7950 Biberach 1-[6,7-Dimethoxy-3,4-dihydro-2H-isochinolin-1-on-2-yl]-3-[N-methyl-N-(2-(3,4-dimethoxy-phenyl)-äthyl)-amino]-propan, dessen physiologisch verträgliche Säureadditionssalze und diese Verbindungen enthaltende Arzneimittel
DE2644833A1 (de) * 1976-10-05 1978-04-20 Boehringer Sohn Ingelheim Neue 1-aryloxy-2-hydroxy-3-alkylenaminopropane und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
ES511914A0 (es) 1983-12-01
ES8401066A1 (es) 1983-12-01
PT74838A (en) 1982-06-01
NO821458L (no) 1982-11-05
PT74838B (en) 1983-12-07
US4473501A (en) 1984-09-25
AU8321782A (en) 1982-11-11
EP0064294A1 (de) 1982-11-10

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