SE8801518D0 - A novel process - Google Patents

A novel process

Info

Publication number
SE8801518D0
SE8801518D0 SE8801518A SE8801518A SE8801518D0 SE 8801518 D0 SE8801518 D0 SE 8801518D0 SE 8801518 A SE8801518 A SE 8801518A SE 8801518 A SE8801518 A SE 8801518A SE 8801518 D0 SE8801518 D0 SE 8801518D0
Authority
SE
Sweden
Prior art keywords
formula
chem
isopropyloxazolidin
hydroxymethyl
sulfonic acid
Prior art date
Application number
SE8801518A
Other languages
English (en)
Original Assignee
Astra Pharma Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Pharma Prod filed Critical Astra Pharma Prod
Priority to SE8801518A priority Critical patent/SE8801518D0/sv
Publication of SE8801518D0 publication Critical patent/SE8801518D0/sv
Priority to AU33115/89A priority patent/AU607323B2/en
Priority to NZ228780A priority patent/NZ228780A/xx
Priority to ES89850122T priority patent/ES2043106T3/es
Priority to EP89850122A priority patent/EP0339006B1/en
Priority to DE8989850122T priority patent/DE68902001T2/de
Priority to AT89850122T priority patent/ATE78026T1/de
Priority to JP1100346A priority patent/JP2550410B2/ja
Priority to US07/529,712 priority patent/US5034535A/en
Priority to GR920402158T priority patent/GR3005827T3/el
Priority to SG2195A priority patent/SG2195G/en
Priority to HK25095A priority patent/HK25095A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • C07D263/24—Oxygen atoms attached in position 2 with hydrocarbon radicals, substituted by oxygen atoms, attached to other ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/06—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton from hydroxy amines by reactions involving the etherification or esterification of hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/28—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
    • C07C217/30—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring
    • C07C217/32—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
SE8801518A 1988-04-22 1988-04-22 A novel process SE8801518D0 (sv)

Priority Applications (12)

Application Number Priority Date Filing Date Title
SE8801518A SE8801518D0 (sv) 1988-04-22 1988-04-22 A novel process
AU33115/89A AU607323B2 (en) 1988-04-22 1989-04-18 A process for the production of S-Metoprolol
NZ228780A NZ228780A (en) 1988-04-22 1989-04-18 Preparation of s-metoprolol and an intermediate (s)-5-hydroxymethyl-3-isopropyloxazolidin-2-one sulphonic acid ester
AT89850122T ATE78026T1 (de) 1988-04-22 1989-04-19 Verfahren zur herstellung von s-metoprolol und dessen zwischenprodukten.
EP89850122A EP0339006B1 (en) 1988-04-22 1989-04-19 Process for preparing s-metoprolol and intermediates therefor
ES89850122T ES2043106T3 (es) 1988-04-22 1989-04-19 Procedimiento para preparar s-metoprolol y sus productos intermedios.
DE8989850122T DE68902001T2 (de) 1988-04-22 1989-04-19 Verfahren zur herstellung von s-metoprolol und dessen zwischenprodukten.
JP1100346A JP2550410B2 (ja) 1988-04-22 1989-04-21 Ｓーメトプロロールの製法
US07/529,712 US5034535A (en) 1988-04-22 1990-05-30 Process for S-metoprolol via oxazolidin-2-one
GR920402158T GR3005827T3 (sv) 1988-04-22 1992-09-30
SG2195A SG2195G (en) 1988-04-22 1995-01-09 Process for preparing S-metoprolol and intermediates therefor
HK25095A HK25095A (en) 1988-04-22 1995-02-23 Process for preparing s-metoprolol and intermediates therefor

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8801518A SE8801518D0 (sv) 1988-04-22 1988-04-22 A novel process

Publications (1)

Publication Number Publication Date
SE8801518D0 true SE8801518D0 (sv) 1988-04-22

Family

ID=20372103

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8801518A SE8801518D0 (sv) 1988-04-22 1988-04-22 A novel process

Country Status (12)

Country Link
US (1) US5034535A (sv)
EP (1) EP0339006B1 (sv)
JP (1) JP2550410B2 (sv)
AT (1) ATE78026T1 (sv)
AU (1) AU607323B2 (sv)
DE (1) DE68902001T2 (sv)
ES (1) ES2043106T3 (sv)
GR (1) GR3005827T3 (sv)
HK (1) HK25095A (sv)
NZ (1) NZ228780A (sv)
SE (1) SE8801518D0 (sv)
SG (1) SG2195G (sv)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU660984B2 (en) * 1991-03-18 1995-07-13 Sepracor, Inc. Composition and method containing optically pure (S) metoprolol
EP0647634A1 (en) * 1993-10-08 1995-04-12 Duphar International Research B.V Method of preparing a heterocyclic intermediate for the production of optically active aryloxy-substituted vicinal aminoalcohols
EP0647633A1 (en) * 1993-10-08 1995-04-12 Duphar International Research B.V Method of preparing a heterocyclic intermediate for the production of optically active aryloxysubstituted vicinal aminoalcohols
US5942633A (en) * 1996-06-19 1999-08-24 Abbott Laboratories Process for the selective alkylation of betaxolol intermediates
US5731463A (en) * 1996-09-23 1998-03-24 Abbott Laboratories Selective alkylation of an alcohol substituted phenol compound
IES20090900A2 (en) * 2008-11-28 2010-07-07 Corden Pharma Ip Ltd Manufacture of beta blockers
KR101379383B1 (ko) * 2012-03-23 2014-04-02 주식회사 알에스텍 고순도 ⒮―메토프롤롤의 제조방법
WO2018146233A1 (en) * 2017-02-10 2018-08-16 Basf Se Process for removal of acid gases from a fluid stream
CN111812228B (zh) * 2020-06-19 2021-11-05 山东省药学科学院 一种超高效液相色谱测定酒石酸美托洛尔及其片剂杂质的方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3641152A (en) * 1968-09-23 1972-02-08 Warner Lambert Pharmaceutical 3 4-dihydronaphthalenoneoxy-2-hydroxy-propylamines
SE386892B (sv) * 1972-07-06 1976-08-23 Haessle Ab Forfarande for framstellning av oxaminoforeningar
CH635573A5 (en) * 1977-03-24 1983-04-15 Sandoz Ag Process for preparing novel 1,2-dihydroxypropane derivatives
US4348393A (en) * 1978-06-09 1982-09-07 Delalande S.A. N-Aryl oxazolidinones, oxazolidinethiones, pyrrolidinones, pyrrolidines and thiazolidinones
US4296242A (en) * 1979-06-06 1981-10-20 Schering Corporation Process for the preparation of chiral 3-amino-2-hydroxypropionic acid and N-blocked derivatives thereof
JPS5767544A (en) * 1980-10-13 1982-04-24 Maruko Seiyaku Kk Improved preparation of 1-2(allylphenyxy)-3-isopropylaminopropan-2-ol
US4473501A (en) * 1981-05-04 1984-09-25 G. D. Searle & Co. Dihydro azino isoquinolines
JPS62108870A (ja) * 1985-11-06 1987-05-20 Kanegafuchi Chem Ind Co Ltd 光学活性５−スルホニルオキシメチル−２−オキサゾリジノン誘導体及びその製造方法
CA1282787C (en) * 1985-12-04 1991-04-09 Ghanshyam Patil Synthesis of aryloxypropanolamines and arylethanolamines
US4990668A (en) * 1985-12-04 1991-02-05 E. I. Du Pont De Nemours And Company Optically active aryloxypropanolamines and arylethanolamines
AU607437B2 (en) * 1986-09-02 1991-03-07 Du Pont Pharmaceuticals Company Resolution of dl-methyl 3-(4-(2-hydroxy-3-isopropylamino) propoxy)phenylpropionate((dl-esmolol))

Also Published As

Publication number Publication date
JPH0222253A (ja) 1990-01-25
SG2195G (en) 1995-06-16
HK25095A (en) 1995-03-03
AU607323B2 (en) 1991-02-28
DE68902001T2 (de) 1993-02-11
EP0339006B1 (en) 1992-07-08
JP2550410B2 (ja) 1996-11-06
GR3005827T3 (sv) 1993-06-07
NZ228780A (en) 1991-10-25
EP0339006A1 (en) 1989-10-25
ATE78026T1 (de) 1992-07-15
AU3311589A (en) 1989-10-26
US5034535A (en) 1991-07-23
DE68902001D1 (de) 1992-08-13
ES2043106T3 (es) 1993-12-16

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