ES511914A0 - Derivados de isoquinolina 1,5-sustituidos. - Google Patents

Derivados de isoquinolina 1,5-sustituidos.

Info

Publication number
ES511914A0
ES511914A0 ES82511914A ES511914A ES511914A0 ES 511914 A0 ES511914 A0 ES 511914A0 ES 82511914 A ES82511914 A ES 82511914A ES 511914 A ES511914 A ES 511914A ES 511914 A0 ES511914 A0 ES 511914A0
Authority
ES
Spain
Prior art keywords
isoquinoline derivatives
substituted isoquinoline
substituted
derivatives
isoquinoline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES82511914A
Other languages
English (en)
Other versions
ES8401066A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GD Searle LLC
Original Assignee
GD Searle LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GD Searle LLC filed Critical GD Searle LLC
Publication of ES8401066A1 publication Critical patent/ES8401066A1/es
Publication of ES511914A0 publication Critical patent/ES511914A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • C07D263/24—Oxygen atoms attached in position 2 with hydrocarbon radicals, substituted by oxygen atoms, attached to other ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ES82511914A 1981-05-04 1982-05-04 Derivados de isoquinolina 1,5-sustituidos. Granted ES511914A0 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26054781A 1981-05-04 1981-05-04
US06/329,789 US4473501A (en) 1981-05-04 1981-12-11 Dihydro azino isoquinolines

Publications (2)

Publication Number Publication Date
ES8401066A1 ES8401066A1 (es) 1983-12-01
ES511914A0 true ES511914A0 (es) 1983-12-01

Family

ID=26948062

Family Applications (1)

Application Number Title Priority Date Filing Date
ES82511914A Granted ES511914A0 (es) 1981-05-04 1982-05-04 Derivados de isoquinolina 1,5-sustituidos.

Country Status (7)

Country Link
US (1) US4473501A (es)
EP (1) EP0064294A1 (es)
AU (1) AU8321782A (es)
DK (1) DK198182A (es)
ES (1) ES511914A0 (es)
NO (1) NO821458L (es)
PT (1) PT74838B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60237070A (ja) * 1984-05-08 1985-11-25 Nisshin Flour Milling Co Ltd 光学活性イソカルボスチリル誘導体の製法
SE8801518D0 (sv) * 1988-04-22 1988-04-22 Astra Pharma Prod A novel process
TW575567B (en) 1998-10-23 2004-02-11 Akzo Nobel Nv Serine protease inhibitor
US7390825B1 (en) 2001-10-18 2008-06-24 Board Of Trustees Of Michigan State University Process for the preparation of oxazolidinones and method of use thereof
US7094789B2 (en) * 2002-07-22 2006-08-22 Asahi Kasei Pharma Corporation 5-substituted isoquinoline derivatives
US7998992B2 (en) 2007-03-30 2011-08-16 Institute Of Medicinal Molecular Design, Inc. Oxazolidinone derivative having inhibitory activity on 11β-hydroxysteroid dehydrogenase type 1

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA536744A (en) * 1957-02-05 Druey Jean Isoquinoline compounds and process of making same
CH307873A (de) * 1952-05-30 1955-06-15 Ciba Geigy Verfahren zur Herstellung einer neuen Isochinolinverbindung.
GB1058822A (en) * 1963-07-30 1967-02-15 Ici Ltd 3-amino-2-hydroxypropoxy heterocyclic derivatives
US4009170A (en) * 1970-08-10 1977-02-22 Sterling Drug Inc. 1-Ethoxy-3,4-dihydroisoquindines
US3753994A (en) * 1970-08-10 1973-08-21 Sterling Drug Inc 1,1'-azinobis(1,2,3,4-tetrahydroisoquinolines)
US3946009A (en) * 1972-05-05 1976-03-23 Merck Sharp & Dohme (I.A.) Corporation 2-(3-Substituted amino-2-hydroxypropoxy)-3-substituted pyrazines
US4115575A (en) * 1973-02-20 1978-09-19 Ciba-Geigy Corporation 2-(3-Amino-2-hydroxy-propoxy)-pyrazines
US4073909A (en) * 1973-10-08 1978-02-14 Sandoz Ltd. Isoquinoline compounds
NL179275C (nl) * 1973-10-24 1986-08-18 Otsuka Pharma Co Ltd Werkwijze voor de bereiding van farmacologisch werkzame glycerol-derivaten en werkwijze voor de bereiding van preparaten die ze bevatten.
JPS538707B2 (es) * 1974-02-05 1978-03-31
JPS5318032B2 (es) * 1974-03-04 1978-06-13
DE2639718A1 (de) * 1976-09-03 1978-03-16 Thomae Gmbh Dr K Neue phenylaethylamine
DE2644833A1 (de) * 1976-10-05 1978-04-20 Boehringer Sohn Ingelheim Neue 1-aryloxy-2-hydroxy-3-alkylenaminopropane und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
NO821458L (no) 1982-11-05
DK198182A (da) 1982-11-05
PT74838B (en) 1983-12-07
US4473501A (en) 1984-09-25
AU8321782A (en) 1982-11-11
ES8401066A1 (es) 1983-12-01
EP0064294A1 (en) 1982-11-10
PT74838A (en) 1982-06-01

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