JPS5371080A - Novel benzimidazole cpds. and process for preparing them - Google Patents

Novel benzimidazole cpds. and process for preparing them

Info

Publication number
JPS5371080A
JPS5371080A JP14849576A JP14849576A JPS5371080A JP S5371080 A JPS5371080 A JP S5371080A JP 14849576 A JP14849576 A JP 14849576A JP 14849576 A JP14849576 A JP 14849576A JP S5371080 A JPS5371080 A JP S5371080A
Authority
JP
Japan
Prior art keywords
cpds
benzimidazole
preparing
novel benzimidazole
ring
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP14849576A
Other languages
Japanese (ja)
Other versions
JPS5850997B2 (en
Inventor
Goro Tsukamoto
Koichiro Yoshino
Toshihiko Takano
Keizo Ito
Hajime Kagaya
Hisashi Nose
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kanebo Ltd
Original Assignee
Kanebo Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kanebo Ltd filed Critical Kanebo Ltd
Priority to JP51148495A priority Critical patent/JPS5850997B2/en
Priority to GB50024/77A priority patent/GB1584296A/en
Priority to US05/856,969 priority patent/US4188486A/en
Priority to FI773660A priority patent/FI63933C/en
Priority to ZA00777168A priority patent/ZA777168B/en
Priority to AU31210/77A priority patent/AU512693B2/en
Priority to NL7713470A priority patent/NL7713470A/en
Priority to BE2056490A priority patent/BE861521A/en
Priority to FR7736647A priority patent/FR2373533A1/en
Priority to CA292,520A priority patent/CA1094074A/en
Priority to SE7713846A priority patent/SE7713846L/en
Priority to DK543177A priority patent/DK543177A/en
Priority to DE19772754299 priority patent/DE2754299A1/en
Priority to NO774166A priority patent/NO147879C/en
Publication of JPS5371080A publication Critical patent/JPS5371080A/en
Priority to SE7907965A priority patent/SE7907965L/en
Priority to DK458379A priority patent/DK145494C/en
Publication of JPS5850997B2 publication Critical patent/JPS5850997B2/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/18—Benzimidazoles; Hydrogenated benzimidazoles with aryl radicals directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

PURPOSE: Benzimidazole cpds. of formula I(R1 is H, halogen, alkyl or alkoxy; R2 is H or alkyl;R1 and R2 are not H at the same time;when R1 is H and the pyridyl ring bonds to the benzimidazole ring at the 2-position, R1 is not methyl bonded to the benzimidazole ring at the 6-position) and their acid salts, e.g. 2-(5-methylpyridine-2-yl) benzimidazole.
COPYRIGHT: (C)1978,JPO&Japio
JP51148495A 1976-12-07 1976-12-07 New benzimidazole compound Expired JPS5850997B2 (en)

Priority Applications (16)

Application Number Priority Date Filing Date Title
JP51148495A JPS5850997B2 (en) 1976-12-07 1976-12-07 New benzimidazole compound
GB50024/77A GB1584296A (en) 1976-12-07 1977-12-01 2-substituted benzimidazole compounds
US05/856,969 US4188486A (en) 1976-12-07 1977-12-02 2-Substituted benzimidazole compounds
FI773660A FI63933C (en) 1976-12-07 1977-12-02 FRUIT PROTECTION FOR THERAPEUTIC USE OF THERAPEUTIC ANALYZATE 2- (ALKYLSUBSTITUERAD PYRIDYL) -BENZIMIDAZOLER
ZA00777168A ZA777168B (en) 1976-12-07 1977-12-02 2-substituted benzimidazole compounds
AU31210/77A AU512693B2 (en) 1976-12-07 1977-12-05 Benzimidazole directly linked with phenyl or pyridine
CA292,520A CA1094074A (en) 1976-12-07 1977-12-06 2-substituted benzimidazole compounds
BE2056490A BE861521A (en) 1976-12-07 1977-12-06 PROCESS FOR PREPARING 2-SUBSTITUTED BENZIMIDAZOLE COMPOUNDS AND THE ACID ADDITION SALTS THEREOF AND PHARMACEUTICAL PREPARATIONS CONTAINING THESE COMPOUNDS AS AN ACTIVE COMPONENT
FR7736647A FR2373533A1 (en) 1976-12-07 1977-12-06 BENZIMIDAZOLES 2-SUBSTITUTES
NL7713470A NL7713470A (en) 1976-12-07 1977-12-06 PROCESS FOR THE PREPARATION OF 2-SUBSTITUTED BENZIMIDAZOLE COMPOUNDS AND THE ACID ADDITION THEREOF AND PHARMACEUTICAL PREPARATIONS CONTAINING THESE COMPONENTS AS AN ACTIVE COMPONENT.
SE7713846A SE7713846L (en) 1976-12-07 1977-12-06 BENZIMIDAZOLES AND PROCEDURES FOR THEIR PREPARATION
DK543177A DK543177A (en) 1976-12-07 1977-12-06 2-SUBSTITUTED BENZIMIDAZOLE COMPOUNDS
DE19772754299 DE2754299A1 (en) 1976-12-07 1977-12-06 SUBSTITUTED BENZIMIDAZOLES, PROCESS FOR THEIR MANUFACTURING AND THE AGENTS CONTAINING THE SUBSTITUTED BENZIMIDAZOLES
NO774166A NO147879C (en) 1976-12-07 1977-12-06 ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC EFFECTIVE 2-SUBSTITUTED BENZIMIDAZOLES
SE7907965A SE7907965L (en) 1976-12-07 1979-09-26 ANTI-INFLAMMATORY AGENT
DK458379A DK145494C (en) 1976-12-07 1979-10-30 ANALOGY PROCEDURE FOR THE PREPARATION OF 2-PHENYL BENZIMIDAZOLD DERIVATIVES

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP51148495A JPS5850997B2 (en) 1976-12-07 1976-12-07 New benzimidazole compound

Publications (2)

Publication Number Publication Date
JPS5371080A true JPS5371080A (en) 1978-06-24
JPS5850997B2 JPS5850997B2 (en) 1983-11-14

Family

ID=15454019

Family Applications (1)

Application Number Title Priority Date Filing Date
JP51148495A Expired JPS5850997B2 (en) 1976-12-07 1976-12-07 New benzimidazole compound

Country Status (3)

Country Link
JP (1) JPS5850997B2 (en)
BE (1) BE861521A (en)
ZA (1) ZA777168B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007260147A (en) * 2006-03-28 2007-10-11 Tadayuki Tange Multipurpose hot-water bottle

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007260147A (en) * 2006-03-28 2007-10-11 Tadayuki Tange Multipurpose hot-water bottle

Also Published As

Publication number Publication date
BE861521A (en) 1978-03-31
ZA777168B (en) 1978-09-27
JPS5850997B2 (en) 1983-11-14

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