DK1942895T3 - Kombinationslægemiddel indeholdende probucol og et tetrazolylalkoxy-dihydrocarbostyrilderivat med superoxidhæmmende virkninger - Google Patents

Kombinationslægemiddel indeholdende probucol og et tetrazolylalkoxy-dihydrocarbostyrilderivat med superoxidhæmmende virkninger

Info

Publication number
DK1942895T3
DK1942895T3 DK06810355.5T DK06810355T DK1942895T3 DK 1942895 T3 DK1942895 T3 DK 1942895T3 DK 06810355 T DK06810355 T DK 06810355T DK 1942895 T3 DK1942895 T3 DK 1942895T3
Authority
DK
Denmark
Prior art keywords
inhibitory effects
drug containing
combination drug
dihydrocarbostyril derivative
superoxide
Prior art date
Application number
DK06810355.5T
Other languages
English (en)
Inventor
Ki Whan Hong
Tomohiro Yoshikawa
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Application granted granted Critical
Publication of DK1942895T3 publication Critical patent/DK1942895T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
    • A61K31/10—Sulfides; Sulfoxides; Sulfones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4704—2-Quinolinones, e.g. carbostyril
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
DK06810355.5T 2005-09-15 2006-09-14 Kombinationslægemiddel indeholdende probucol og et tetrazolylalkoxy-dihydrocarbostyrilderivat med superoxidhæmmende virkninger DK1942895T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US71695405P 2005-09-15 2005-09-15
US76177506P 2006-01-25 2006-01-25
PCT/JP2006/318675 WO2007032557A1 (en) 2005-09-15 2006-09-14 Combination drug containing probucol and a tetrazolylalkoxy-dihydrocarbostyril derivative with superoxide supressant effects

Publications (1)

Publication Number Publication Date
DK1942895T3 true DK1942895T3 (da) 2012-03-05

Family

ID=37420867

Family Applications (1)

Application Number Title Priority Date Filing Date
DK06810355.5T DK1942895T3 (da) 2005-09-15 2006-09-14 Kombinationslægemiddel indeholdende probucol og et tetrazolylalkoxy-dihydrocarbostyrilderivat med superoxidhæmmende virkninger

Country Status (21)

Country Link
US (2) US8580818B2 (da)
EP (2) EP1942895B1 (da)
JP (2) JP5179354B2 (da)
KR (1) KR101299320B1 (da)
AR (1) AR057520A1 (da)
AU (1) AU2006289752B2 (da)
BR (1) BRPI0616223A2 (da)
CA (1) CA2620296C (da)
CY (1) CY1112716T1 (da)
DK (1) DK1942895T3 (da)
ES (1) ES2378896T3 (da)
HK (1) HK1122996A1 (da)
IL (1) IL189751A0 (da)
MY (1) MY145787A (da)
NO (1) NO20081811L (da)
PL (1) PL1942895T3 (da)
PT (1) PT1942895E (da)
RU (1) RU2411945C2 (da)
SG (1) SG165379A1 (da)
TW (1) TWI372053B (da)
WO (1) WO2007032557A1 (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR065588A1 (es) * 2007-03-09 2009-06-17 Otsuka Pharma Co Ltd Un medicamento para tratar enfermedad pulmonar obstructiva cronica
AR070816A1 (es) * 2008-03-14 2010-05-05 Otsuka Pharma Co Ltd Farmaco de combinacion para tratar trastornos vasculares

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5535019A (en) 1978-09-01 1980-03-11 Otsuka Pharmaceut Co Ltd Carbostyryl derivative
JPH04193836A (ja) 1990-11-26 1992-07-13 Banyu Pharmaceut Co Ltd 抗高脂血症剤
JPH107590A (ja) 1996-06-24 1998-01-13 Chugai Pharmaceut Co Ltd 脳循環障害後遺症または脳虚血後の脳神経障害の治療剤
FR2751540B1 (fr) 1996-07-26 1998-10-16 Sanofi Sa Composition pharmaceutique antithrombotique
EP0946178A4 (en) 1996-09-18 2003-05-07 Merck & Co Inc COMBINATION THERAPY TO REDUCE THE RISKS OF HEART CIRCULAR DISEASES
US6245797B1 (en) 1997-10-22 2001-06-12 Merck & Co., Inc. Combination therapy for reducing the risks associated with cardio-and-cerebrovascular disease
AU1387399A (en) * 1997-11-10 1999-05-31 Vyrex Corporation Probucol esters and uses thereof
US6235311B1 (en) 1998-03-18 2001-05-22 Bristol-Myers Squibb Company Pharmaceutical composition containing a combination of a statin and aspirin and method
WO2000021507A2 (de) 1998-10-12 2000-04-20 Andreas Bockelmann Pharmazeutisch wirksame zusammensetzung
ATE326240T2 (de) 2000-04-10 2006-06-15 Nicholas John Wald Zusammensetzung zur prävention kardiovaskulärer erkrankungen
US20020115728A1 (en) 2000-09-05 2002-08-22 Roland Stocker Compositions and methods for treating cardiovascular disorders
CZ20032031A3 (cs) * 2001-01-26 2003-12-17 Schering Corporation Farmaceutický prostředek
US6576256B2 (en) 2001-08-28 2003-06-10 The Brigham And Women's Hospital, Inc. Treatment of patients at elevated cardiovascular risk with a combination of a cholesterol-lowering agent, an inhibitor of the renin-angiotensin system, and aspirin
JP2003192573A (ja) * 2001-12-25 2003-07-09 Otsuka Pharmaceut Factory Inc 経口ゲル製剤
US20030181461A1 (en) 2002-01-25 2003-09-25 Lautt Wilfred Wayne Use of phosphodiesterase antagonists to treat insulin resistance
US6743806B2 (en) 2002-10-23 2004-06-01 Otsuka Pharmaceutical Company, Limited Active oxygen scavenger
JP2005232059A (ja) 2004-02-18 2005-09-02 Iichiro Shimomura 低アディポネクチン血症予防・治療剤
CN101193656B (zh) 2005-06-08 2011-03-02 兴和株式会社 甘油三酸酯降低剂
JP4193836B2 (ja) 2005-10-24 2008-12-10 ブラザー工業株式会社 インク噴射装置の製造方法

Also Published As

Publication number Publication date
AU2006289752A1 (en) 2007-03-22
HK1122996A1 (en) 2009-06-05
CY1112716T1 (el) 2016-02-10
SG165379A1 (en) 2010-10-28
PT1942895E (pt) 2012-03-29
EP1942895B1 (en) 2012-02-01
ES2378896T3 (es) 2012-04-18
TW200744597A (en) 2007-12-16
PL1942895T3 (pl) 2012-07-31
BRPI0616223A2 (pt) 2011-06-14
AR057520A1 (es) 2007-12-05
CA2620296C (en) 2013-10-22
IL189751A0 (en) 2008-12-29
JP2013014605A (ja) 2013-01-24
MY145787A (en) 2012-04-30
AU2006289752B2 (en) 2011-06-09
CA2620296A1 (en) 2007-03-22
US20090176826A1 (en) 2009-07-09
EP1942895A1 (en) 2008-07-16
JP5179354B2 (ja) 2013-04-10
KR20080049822A (ko) 2008-06-04
RU2008114512A (ru) 2009-10-20
US8580818B2 (en) 2013-11-12
KR101299320B1 (ko) 2013-09-03
NO20081811L (no) 2008-04-14
JP5603393B2 (ja) 2014-10-08
WO2007032557A1 (en) 2007-03-22
US20140045889A1 (en) 2014-02-13
EP2275106A1 (en) 2011-01-19
JP2009508804A (ja) 2009-03-05
TWI372053B (en) 2012-09-11
RU2411945C2 (ru) 2011-02-20

Similar Documents

Publication Publication Date Title
NO20081604L (no) Nitrogeninneholdende heterocyklisk forbindelse og farmasøytisk anvendelse derav
DK1894567T3 (da) Ledsagende farmaceutiske midler og anvendelse deraf
DK2079485T3 (da) Phenylpropionamidforbindelser og anvendelsen deraf
DK2081955T3 (da) Metastinderivater og anvendelse deraf
DK2001556T3 (da) Thioninium-forbindelser og anvendelse deraf
DE602007001088D1 (de) Tintenpatrone und Aufzeichnungsvorrichtung
DK2957312T3 (da) Inhaleringsindretning
DK1885716T3 (da) Thiazolderivater og anvendelse deraf
HK1118829A1 (en) Thiazole derivatives and use thereof
DE602006009589D1 (de) Treibkette und Antriebsvorrichtung
DE602006004713D1 (de) Trifluormethylbenzamidderivate und therapeutische verwendungen dafür
DK2022735T3 (da) Overføringsapparat og overføringsgenstands-inspektionsapparat
DK2158199T3 (da) Piperidinforbindelser og anvendelser deraf
GB0516069D0 (en) Pharmaceutical and use thereof
ITMI20061766A1 (it) Prepolimeri silano-terminati e relativi formulati adesivo-sigillanti
EP2077262A4 (en) IMINOPYRIDINE DERIVATIVES AND THEIR USE
EP2111226A4 (en) CYCLITOES AND THEIR DERIVATIVES AND THERAPEUTIC APPLICATIONS THEREOF
DE602006002678D1 (de) Treibkette und Treibvorrichtung
DK2029561T3 (da) Tricyclisk forbindelse og farmaceutisk anvendelse deraf
DE112006002272T8 (de) Katheter und Katheter-Kit
DE112007001250A5 (de) Planarer Direktantrieb und dazugehörige Sensoreinheit
AT508430A5 (de) Formbauteil und dessen verwendung
DK1954288T3 (da) Amidin-derivater og anvendelse deraf som lægemiddel
DK1942895T3 (da) Kombinationslægemiddel indeholdende probucol og et tetrazolylalkoxy-dihydrocarbostyrilderivat med superoxidhæmmende virkninger
DK1976853T3 (da) Nye forbindelser og anvendelse heraf