AR070816A1 - Farmaco de combinacion para tratar trastornos vasculares - Google Patents

Farmaco de combinacion para tratar trastornos vasculares

Info

Publication number
AR070816A1
AR070816A1 ARP090100806A ARP090100806A AR070816A1 AR 070816 A1 AR070816 A1 AR 070816A1 AR P090100806 A ARP090100806 A AR P090100806A AR P090100806 A ARP090100806 A AR P090100806A AR 070816 A1 AR070816 A1 AR 070816A1
Authority
AR
Argentina
Prior art keywords
combination
salt
arterial disease
carbostiryl
pharmaco
Prior art date
Application number
ARP090100806A
Other languages
English (en)
Inventor
Kensuke Orito
Hiroshi Ohno
Takao Urabe
Yuji Ueno
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41065644&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR070816(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of AR070816A1 publication Critical patent/AR070816A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4704—2-Quinolinones, e.g. carbostyril
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Reivindicacion 1: Una combinacion caracterizada porque comprende como componentes activos un derivado de carbostirilo de la formula general (1) donde A es un grupo alquileno inferior, R es un grupo cicloalquilo, el enlace entre las posiciones 3 y 4 del esqueleto del carbostirilo es un enlace simple o un enlace doble, o una sal del mismo; y carnitina o una sal de la misma. Reivindicacion 2: La combinacion de la reivindicacion 1 caracterizada porque el derivado de carbostirilo es 6-[4-(1-ciclohexil-1H-tetrazol-5-il)butoxi]-3,4- dihidrocarbostirilo o una sal del mismo. Reivindicacion 3: Un medicamento para tratar la enfermedad arterial periférica oclusiva, caracterizado porque comprende la combinacion de la reivindicacion 1 o 2. Reivindicacion 5: El medicamento de la reivindicacion 3 o 4 caracterizado porque la enfermedad arterial periférica oclusiva es una enfermedad arterial oclusiva aguda, tromboangeítis obliterante, arteriosclerosis obliterante, estenosis espinal lumbar, o claudicacion intermitente.
ARP090100806A 2008-03-14 2009-03-06 Farmaco de combinacion para tratar trastornos vasculares AR070816A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2008065448 2008-03-14
JP2008118289 2008-04-30

Publications (1)

Publication Number Publication Date
AR070816A1 true AR070816A1 (es) 2010-05-05

Family

ID=41065644

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP090100806A AR070816A1 (es) 2008-03-14 2009-03-06 Farmaco de combinacion para tratar trastornos vasculares

Country Status (14)

Country Link
US (2) US8980919B2 (es)
EP (1) EP2254578A2 (es)
JP (2) JP5574989B2 (es)
KR (1) KR101632448B1 (es)
CN (2) CN102026638B (es)
AR (1) AR070816A1 (es)
AU (1) AU2009224214B2 (es)
BR (1) BRPI0909291A8 (es)
CA (1) CA2717351A1 (es)
CL (1) CL2009000589A1 (es)
PE (1) PE20091675A1 (es)
RU (1) RU2506950C2 (es)
TW (1) TW200944204A (es)
WO (1) WO2009113741A2 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102933205B (zh) 2010-04-28 2014-08-13 诺弗米克斯有限公司 西洛他唑共晶和组合物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4968719A (en) * 1989-04-03 1990-11-06 Sigma Tau, Industrie Farmaceutiche Riunite Spa Method for treating vascular disease
EP1133289A1 (en) 1998-11-26 2001-09-19 Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. Use of fumarate salt of l-carnitine or its alkanoyl derivatives in ischaemia
IT1306722B1 (it) 1999-10-08 2001-10-02 Sigma Tau Healthscience Spa Composizione per la prevenzione e/o il trattamento di disfunzionicircolatorie, comprendente derivati della l-carnitina ed estratti di
US6871689B2 (en) * 2001-02-07 2005-03-29 Disa Industries A/S Sand moulding machine with improved sand blow
US20060160896A1 (en) * 2002-02-04 2006-07-20 Jallal Messadek Therapeutic treatment
TWI323660B (en) 2003-02-25 2010-04-21 Otsuka Pharma Co Ltd Pten inhibitor or maxi-k channels opener
CA2620296C (en) * 2005-09-15 2013-10-22 Otsuka Pharmaceutical Co., Ltd. Combination drug containing probucol and a tetrazolylalkoxy-dihydrocarbostyril derivative with superoxide supressant effects

Also Published As

Publication number Publication date
US8980919B2 (en) 2015-03-17
CN104906097A (zh) 2015-09-16
KR20100123909A (ko) 2010-11-25
AU2009224214A1 (en) 2009-09-17
WO2009113741A3 (en) 2010-04-29
CL2009000589A1 (es) 2010-03-26
KR101632448B1 (ko) 2016-06-21
TW200944204A (en) 2009-11-01
RU2506950C2 (ru) 2014-02-20
PE20091675A1 (es) 2009-11-16
RU2010141982A (ru) 2012-04-20
EP2254578A2 (en) 2010-12-01
US20150150865A1 (en) 2015-06-04
JP5837128B2 (ja) 2015-12-24
BRPI0909291A8 (pt) 2016-07-12
US20110015224A1 (en) 2011-01-20
JP5574989B2 (ja) 2014-08-20
CN102026638A (zh) 2011-04-20
AU2009224214B2 (en) 2013-12-12
CA2717351A1 (en) 2009-09-17
WO2009113741A2 (en) 2009-09-17
JP2014159458A (ja) 2014-09-04
BRPI0909291A2 (pt) 2015-08-11
CN102026638B (zh) 2015-06-24
JP2011513480A (ja) 2011-04-28

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