DK18985A - Fremgangsmaade til fremstilling af et farmakologisk virksomt sulfonylurinstofderivat - Google Patents

Fremgangsmaade til fremstilling af et farmakologisk virksomt sulfonylurinstofderivat Download PDF

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Publication number
DK18985A
DK18985A DK18985A DK18985A DK18985A DK 18985 A DK18985 A DK 18985A DK 18985 A DK18985 A DK 18985A DK 18985 A DK18985 A DK 18985A DK 18985 A DK18985 A DK 18985A
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DK
Denmark
Prior art keywords
sulphonylurine
ingredients
preparing
procedure
pharmacologically effective
Prior art date
Application number
DK18985A
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English (en)
Other versions
DK18985D0 (da
Inventor
Mikael Ulf Johan Dahlstroem
Yngve Valdemar Malmen
Original Assignee
Medica Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medica Pharma Co Ltd filed Critical Medica Pharma Co Ltd
Publication of DK18985D0 publication Critical patent/DK18985D0/da
Publication of DK18985A publication Critical patent/DK18985A/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D521/00Heterocyclic compounds containing unspecified hetero rings

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)

Description

Figure DK18985AD00021
med N cyklohexyl-trikloreddikesyreamid med formlen
Figure DK18985AD00022
idet reaktionen ifølge opfindelsen udføres i nærværelse af et polært aprotisk opløsningsmiddel såsom N-metylpyrrolidon, Ν,Ν-dimetylformamid, Ν,Ν-dimetylacetamid eller dimetylsulfoxyd under vandfri betingelser og i nærværelse af en base såsom et alkalimetalalkoholat, -amid eller -hydrid ved en temperatur på 40-100°C i 2-5 timer.
Det opnås et højt udbytte af rent materiale der ikke behøver rensning eller kun rensning i lille omfang.
DK18985A 1984-01-19 1985-01-15 Fremgangsmaade til fremstilling af et farmakologisk virksomt sulfonylurinstofderivat DK18985A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI840209A FI69303C (fi) 1984-01-19 1984-01-19 Foerfarande foer framstaellning av ett farmakologiskt verksamtsulfonylureaderivat
FI840209 1984-01-19

Publications (2)

Publication Number Publication Date
DK18985D0 DK18985D0 (da) 1985-01-15
DK18985A true DK18985A (da) 1985-07-20

Family

ID=8518397

Family Applications (1)

Application Number Title Priority Date Filing Date
DK18985A DK18985A (da) 1984-01-19 1985-01-15 Fremgangsmaade til fremstilling af et farmakologisk virksomt sulfonylurinstofderivat

Country Status (9)

Country Link
EP (1) EP0149592A3 (da)
CS (1) CS249534B2 (da)
DD (1) DD228251A5 (da)
DK (1) DK18985A (da)
FI (1) FI69303C (da)
NO (1) NO850217L (da)
PL (1) PL251605A1 (da)
SU (1) SU1340584A3 (da)
ZA (1) ZA8410079B (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107434788B (zh) * 2017-09-11 2018-06-15 威海迪素制药有限公司 一种格列吡嗪的制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU162761B (da) * 1971-04-06 1973-04-28

Also Published As

Publication number Publication date
CS249534B2 (en) 1987-03-12
ZA8410079B (en) 1985-08-28
FI840209A0 (fi) 1984-01-19
EP0149592A2 (en) 1985-07-24
EP0149592A3 (en) 1986-06-04
PL251605A1 (en) 1985-10-22
FI840209A (fi) 1985-07-20
DD228251A5 (de) 1985-10-09
NO850217L (no) 1985-07-22
FI69303B (fi) 1985-09-30
DK18985D0 (da) 1985-01-15
SU1340584A3 (ru) 1987-09-23
FI69303C (fi) 1986-01-10

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