DK0992495T3 - Fremgangsmåde til opnåelse af quinaprilhydrochlorid og solvater, der er nyttige ved isolation og rensning af quinaprilhydrochlorid - Google Patents

Fremgangsmåde til opnåelse af quinaprilhydrochlorid og solvater, der er nyttige ved isolation og rensning af quinaprilhydrochlorid

Info

Publication number
DK0992495T3
DK0992495T3 DK98920547T DK98920547T DK0992495T3 DK 0992495 T3 DK0992495 T3 DK 0992495T3 DK 98920547 T DK98920547 T DK 98920547T DK 98920547 T DK98920547 T DK 98920547T DK 0992495 T3 DK0992495 T3 DK 0992495T3
Authority
DK
Denmark
Prior art keywords
quinapril hydrochloride
solvate
quinapril
obtaining
isolation
Prior art date
Application number
DK98920547T
Other languages
English (en)
Inventor
Llagostera Montser Monsalvatje
Sanmart Marti Bartra
Navarro Jaime Tomas
Torres Salvador Puig
Original Assignee
Esteve Quimica Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Esteve Quimica Sa filed Critical Esteve Quimica Sa
Application granted granted Critical
Publication of DK0992495T3 publication Critical patent/DK0992495T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK98920547T 1997-05-29 1998-05-25 Fremgangsmåde til opnåelse af quinaprilhydrochlorid og solvater, der er nyttige ved isolation og rensning af quinaprilhydrochlorid DK0992495T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES09701169A ES2122941B1 (es) 1997-05-29 1997-05-29 Procedimiento para la obtencion de quinapril clorhidrato y solvatos utiles para el aislamiento y purificacion de quinapril clorhidrato.
PCT/ES1998/000145 WO1998054149A1 (es) 1997-05-29 1998-05-25 Procedimiento para la obtención de quinapril clorhidrato y solvatos utiles para el aislamiento y purificación de quinapril clorhidrato

Publications (1)

Publication Number Publication Date
DK0992495T3 true DK0992495T3 (da) 2004-06-01

Family

ID=8299498

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98920547T DK0992495T3 (da) 1997-05-29 1998-05-25 Fremgangsmåde til opnåelse af quinaprilhydrochlorid og solvater, der er nyttige ved isolation og rensning af quinaprilhydrochlorid

Country Status (13)

Country Link
US (2) US6617457B1 (da)
EP (1) EP0992495B1 (da)
JP (1) JP2002502386A (da)
KR (1) KR100477713B1 (da)
AT (1) ATE258920T1 (da)
AU (1) AU730140B2 (da)
CA (1) CA2293705C (da)
DE (1) DE69821483T2 (da)
DK (1) DK0992495T3 (da)
ES (1) ES2122941B1 (da)
PT (1) PT992495E (da)
WO (1) WO1998054149A1 (da)
ZA (1) ZA984466B (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030225124A1 (en) * 1999-08-31 2003-12-04 Spiridon Spireas Stable formulations of ACE inhibitors, and methods for preparation thereof
ES2286325T3 (es) 2002-12-16 2007-12-01 Lupin Limited Forma cristalina de clorhidrato de quinapril y proceso para su preparacion.
WO2007054966A2 (en) * 2005-09-13 2007-05-18 Aarti Healthcare Limited A process for the preparation of highly pure crystalline quinapril hydrochloride
WO2007069268A2 (en) * 2005-10-14 2007-06-21 Sun Pharmaceutical Industries Limited A process for the preparation of substantially pure 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid derivatives
WO2009053994A1 (en) * 2007-10-26 2009-04-30 Matrix Laboratories Limited Process for preparing pure amorphous quinapril hydrochloride

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4344949A (en) * 1980-10-03 1982-08-17 Warner-Lambert Company Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids
IN156096B (da) * 1981-03-19 1985-05-11 Usv Pharma Corp
JPS58188857A (ja) * 1982-04-26 1983-11-04 Takeda Chem Ind Ltd テトラヒドロイソキノリン誘導体
DE3333455A1 (de) * 1983-09-16 1985-04-11 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung n-alkylierter dipeptide und deren estern
DE3333454A1 (de) * 1983-09-16 1985-04-11 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von n-alkylierten dipeptiden und deren estern
US4761479A (en) * 1987-03-30 1988-08-02 Warner-Lambert Company Crystalline quinapril and a process for producing the same
JPH01275546A (ja) * 1988-04-26 1989-11-06 Nisso Yuka Kogyo Kk 安息香酸ソーダの単離方法
DE4206697A1 (de) * 1992-03-04 1993-09-09 Hoechst Ag Verfahren zur herstellung von modifizierten phenolharzen
JP3211396B2 (ja) * 1992-08-26 2001-09-25 住友化学工業株式会社 アクリル酸及び酢酸の回収方法

Also Published As

Publication number Publication date
ZA984466B (en) 1998-12-01
EP0992495A1 (en) 2000-04-12
CA2293705A1 (en) 1998-12-03
JP2002502386A (ja) 2002-01-22
KR100477713B1 (ko) 2005-03-18
AU7336598A (en) 1998-12-30
KR20010013167A (ko) 2001-02-26
USRE39888E1 (en) 2007-10-16
PT992495E (pt) 2004-06-30
WO1998054149A1 (es) 1998-12-03
DE69821483T2 (de) 2005-01-13
ES2122941A1 (es) 1998-12-16
EP0992495B1 (en) 2004-02-04
ATE258920T1 (de) 2004-02-15
ES2122941B1 (es) 1999-07-01
AU730140B2 (en) 2001-03-01
US6617457B1 (en) 2003-09-09
CA2293705C (en) 2008-03-18
DE69821483D1 (de) 2004-03-11

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