ATE258920T1 - Verfahren zur gewinnung von chinaprylhydrochlorid und solvaten, die bei der isolierung und reinigung von chinaprylhydrochlorid nützlich sind - Google Patents
Verfahren zur gewinnung von chinaprylhydrochlorid und solvaten, die bei der isolierung und reinigung von chinaprylhydrochlorid nützlich sindInfo
- Publication number
- ATE258920T1 ATE258920T1 AT98920547T AT98920547T ATE258920T1 AT E258920 T1 ATE258920 T1 AT E258920T1 AT 98920547 T AT98920547 T AT 98920547T AT 98920547 T AT98920547 T AT 98920547T AT E258920 T1 ATE258920 T1 AT E258920T1
- Authority
- AT
- Austria
- Prior art keywords
- hydrochloride
- chinapryl
- obtaining
- solvate
- isolation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES09701169A ES2122941B1 (es) | 1997-05-29 | 1997-05-29 | Procedimiento para la obtencion de quinapril clorhidrato y solvatos utiles para el aislamiento y purificacion de quinapril clorhidrato. |
| PCT/ES1998/000145 WO1998054149A1 (es) | 1997-05-29 | 1998-05-25 | Procedimiento para la obtención de quinapril clorhidrato y solvatos utiles para el aislamiento y purificación de quinapril clorhidrato |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE258920T1 true ATE258920T1 (de) | 2004-02-15 |
Family
ID=8299498
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98920547T ATE258920T1 (de) | 1997-05-29 | 1998-05-25 | Verfahren zur gewinnung von chinaprylhydrochlorid und solvaten, die bei der isolierung und reinigung von chinaprylhydrochlorid nützlich sind |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | USRE39888E1 (de) |
| EP (1) | EP0992495B1 (de) |
| JP (1) | JP2002502386A (de) |
| KR (1) | KR100477713B1 (de) |
| AT (1) | ATE258920T1 (de) |
| AU (1) | AU730140B2 (de) |
| CA (1) | CA2293705C (de) |
| DE (1) | DE69821483T2 (de) |
| DK (1) | DK0992495T3 (de) |
| ES (1) | ES2122941B1 (de) |
| PT (1) | PT992495E (de) |
| WO (1) | WO1998054149A1 (de) |
| ZA (1) | ZA984466B (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030225124A1 (en) * | 1999-08-31 | 2003-12-04 | Spiridon Spireas | Stable formulations of ACE inhibitors, and methods for preparation thereof |
| WO2004054980A1 (en) * | 2002-12-16 | 2004-07-01 | Lupin Limited | Crystalline form of quinapril hydrochloride and process for preparing the same |
| WO2007054966A2 (en) * | 2005-09-13 | 2007-05-18 | Aarti Healthcare Limited | A process for the preparation of highly pure crystalline quinapril hydrochloride |
| WO2007069268A2 (en) * | 2005-10-14 | 2007-06-21 | Sun Pharmaceutical Industries Limited | A process for the preparation of substantially pure 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid derivatives |
| WO2009053994A1 (en) * | 2007-10-26 | 2009-04-30 | Matrix Laboratories Limited | Process for preparing pure amorphous quinapril hydrochloride |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4344949A (en) * | 1980-10-03 | 1982-08-17 | Warner-Lambert Company | Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids |
| IN156096B (de) * | 1981-03-19 | 1985-05-11 | Usv Pharma Corp | |
| JPS58188857A (ja) * | 1982-04-26 | 1983-11-04 | Takeda Chem Ind Ltd | テトラヒドロイソキノリン誘導体 |
| DE3333454A1 (de) * | 1983-09-16 | 1985-04-11 | Hoechst Ag, 6230 Frankfurt | Verfahren zur herstellung von n-alkylierten dipeptiden und deren estern |
| DE3333455A1 (de) * | 1983-09-16 | 1985-04-11 | Hoechst Ag, 6230 Frankfurt | Verfahren zur herstellung n-alkylierter dipeptide und deren estern |
| US4761479A (en) * | 1987-03-30 | 1988-08-02 | Warner-Lambert Company | Crystalline quinapril and a process for producing the same |
| JPH01275546A (ja) * | 1988-04-26 | 1989-11-06 | Nisso Yuka Kogyo Kk | 安息香酸ソーダの単離方法 |
| DE4206697A1 (de) * | 1992-03-04 | 1993-09-09 | Hoechst Ag | Verfahren zur herstellung von modifizierten phenolharzen |
| JP3211396B2 (ja) * | 1992-08-26 | 2001-09-25 | 住友化学工業株式会社 | アクリル酸及び酢酸の回収方法 |
-
1997
- 1997-05-29 ES ES09701169A patent/ES2122941B1/es not_active Expired - Fee Related
-
1998
- 1998-05-25 EP EP98920547A patent/EP0992495B1/de not_active Expired - Lifetime
- 1998-05-25 DK DK98920547T patent/DK0992495T3/da active
- 1998-05-25 AT AT98920547T patent/ATE258920T1/de not_active IP Right Cessation
- 1998-05-25 DE DE1998621483 patent/DE69821483T2/de not_active Expired - Lifetime
- 1998-05-25 JP JP50027999A patent/JP2002502386A/ja active Pending
- 1998-05-25 US US11/022,424 patent/USRE39888E1/en not_active Expired - Fee Related
- 1998-05-25 AU AU73365/98A patent/AU730140B2/en not_active Ceased
- 1998-05-25 WO PCT/ES1998/000145 patent/WO1998054149A1/es active IP Right Grant
- 1998-05-25 CA CA002293705A patent/CA2293705C/en not_active Expired - Fee Related
- 1998-05-25 PT PT98920547T patent/PT992495E/pt unknown
- 1998-05-25 KR KR10-1999-7011151A patent/KR100477713B1/ko not_active IP Right Cessation
- 1998-05-25 US US09/424,673 patent/US6617457B1/en not_active Ceased
- 1998-05-26 ZA ZA984466A patent/ZA984466B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2293705A1 (en) | 1998-12-03 |
| US6617457B1 (en) | 2003-09-09 |
| ES2122941A1 (es) | 1998-12-16 |
| CA2293705C (en) | 2008-03-18 |
| PT992495E (pt) | 2004-06-30 |
| DE69821483D1 (de) | 2004-03-11 |
| ES2122941B1 (es) | 1999-07-01 |
| USRE39888E1 (en) | 2007-10-16 |
| EP0992495B1 (de) | 2004-02-04 |
| DK0992495T3 (da) | 2004-06-01 |
| ZA984466B (en) | 1998-12-01 |
| KR20010013167A (ko) | 2001-02-26 |
| DE69821483T2 (de) | 2005-01-13 |
| KR100477713B1 (ko) | 2005-03-18 |
| EP0992495A1 (de) | 2000-04-12 |
| AU730140B2 (en) | 2001-03-01 |
| AU7336598A (en) | 1998-12-30 |
| WO1998054149A1 (es) | 1998-12-03 |
| JP2002502386A (ja) | 2002-01-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0992495 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |