DK1762626T3 - Signalamplifikation under anvendelse af et syntetisk zymogen - Google Patents

Signalamplifikation under anvendelse af et syntetisk zymogen

Info

Publication number
DK1762626T3
DK1762626T3 DK06011717.3T DK06011717T DK1762626T3 DK 1762626 T3 DK1762626 T3 DK 1762626T3 DK 06011717 T DK06011717 T DK 06011717T DK 1762626 T3 DK1762626 T3 DK 1762626T3
Authority
DK
Denmark
Prior art keywords
zymogens
signal amplification
enzyme
substrate
synthetic zymogen
Prior art date
Application number
DK06011717.3T
Other languages
English (en)
Inventor
Gerard J Colpas
Mitchell C Sanders
Shite Sebastian
Original Assignee
Systagenix Wound Man Ip Co Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Systagenix Wound Man Ip Co Bv filed Critical Systagenix Wound Man Ip Co Bv
Application granted granted Critical
Publication of DK1762626T3 publication Critical patent/DK1762626T3/da

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • C12Q1/10Enterobacteria
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • C12Q1/14Streptococcus; Staphylococcus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/581Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with enzyme label (including co-enzymes, co-factors, enzyme inhibitors or substrates)
DK06011717.3T 2003-09-02 2004-09-02 Signalamplifikation under anvendelse af et syntetisk zymogen DK1762626T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US49984603P 2003-09-02 2003-09-02
EP04783048A EP1670936A1 (en) 2003-09-02 2004-09-02 Signal amplification using a synthetic zymogen

Publications (1)

Publication Number Publication Date
DK1762626T3 true DK1762626T3 (da) 2011-03-14

Family

ID=34272880

Family Applications (1)

Application Number Title Priority Date Filing Date
DK06011717.3T DK1762626T3 (da) 2003-09-02 2004-09-02 Signalamplifikation under anvendelse af et syntetisk zymogen

Country Status (11)

Country Link
US (2) US8039228B2 (da)
EP (2) EP1762626B1 (da)
JP (3) JP2007503833A (da)
AT (1) ATE491806T1 (da)
AU (3) AU2004269425A1 (da)
CA (2) CA2537529A1 (da)
DE (1) DE602004030623D1 (da)
DK (1) DK1762626T3 (da)
ES (1) ES2357547T3 (da)
PT (1) PT1762626E (da)
WO (1) WO2005021780A1 (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003063693A2 (en) 2002-01-31 2003-08-07 Expressive Constructs, Inc. Method for detecting microorganisms
DK1762626T3 (da) * 2003-09-02 2011-03-14 Systagenix Wound Man Ip Co Bv Signalamplifikation under anvendelse af et syntetisk zymogen
CA2557612C (en) * 2003-11-03 2014-06-17 Ethicon, Inc. Methods, peptides and biosensors useful for detecting a broad spectrum of bacteria
WO2005042771A2 (en) * 2003-11-03 2005-05-12 Ethicon, Inc. Colorimetric substrates, colorimetric sensors, and methods of use
JP5089058B2 (ja) * 2006-03-01 2012-12-05 旭化成ファーマ株式会社 試料中の銅イオン濃度測定用酵素
AT509355B1 (de) * 2010-02-10 2012-04-15 Univ Graz Tech Testanordnung
EP2896963B1 (en) 2011-01-31 2019-01-30 Woundchek Laboratories B.V. Wound prognosis
GB201116523D0 (en) 2011-09-23 2011-11-09 Systagenix Wound Man Ip Co Bv Wound prognosis
CN106905427A (zh) 2011-03-18 2017-06-30 艺杰斯有限责任公司 用于抑制炎症的肽
US9303063B2 (en) 2011-03-18 2016-04-05 Duke University Peptide compounds for suppressing inflammation
CA2846247A1 (en) * 2011-09-16 2013-03-21 Credo Biomedical Pte Ltd Molecular diagnostic assay device and method of use
US9970933B2 (en) * 2011-10-06 2018-05-15 Ingibio, Ltd. Method for manufacturing multiple-diagnosis membrane sensor by using screen printing
WO2014146712A1 (en) * 2013-03-20 2014-09-25 Metgen Oy Method for saving energy in paper production
WO2015191380A1 (en) * 2014-06-10 2015-12-17 Thomson Licensing Set top box having paste-in-hole tuner shield
US20190360019A1 (en) * 2016-11-16 2019-11-28 Universal Biosensors Pty Ltd Cleavage event transduction methods and products
CN106916797B (zh) * 2017-02-27 2019-12-17 中国科学院成都生物研究所 一种高活性漆酶突变体蛋白及其制备方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2684488A (en) * 1988-06-27 1990-01-04 Carter-Wallace, Inc. Test device and method for colored particle immunoassay
JPH0480651A (ja) * 1990-07-23 1992-03-13 Kanzaki Paper Mfg Co Ltd 固定化酵素を用いるフロー型測定装置
JP3074361B2 (ja) * 1992-07-15 2000-08-07 セイコーインスツルメンツ株式会社 定量分析装置
ATE226642T1 (de) * 1994-07-07 2002-11-15 Tno Modifizierte proenzyme als substrate für proteolische enzyme
JPH08332077A (ja) * 1995-06-07 1996-12-17 Hitachi Ltd サンプルカップおよび生化学分析装置
JPH0923898A (ja) * 1995-07-13 1997-01-28 Nissui Pharm Co Ltd フェニルアラニンデアミナーゼ試験用反応シート
US20030096315A1 (en) * 2000-05-03 2003-05-22 Sanders Mitchell C. Device for detecting bacterial contamination and method of use
WO2002016634A1 (en) 2000-08-22 2002-02-28 Cygene, Inc. Methods and compositions for ultra low copy number analyte detection
JP4830079B2 (ja) 2000-11-29 2011-12-07 国立感染症研究所長 プロテアーゼ活性の測定方法
EP1448991A2 (en) 2001-04-09 2004-08-25 Fraunhofer-Gesellschaft Zur Förderung Der Angewandten Forschung E.V. Activated enzyme-linked detection systems for detecting and quantifying nucleid acids, antigens, antibodies and other analytes
JP2003169697A (ja) * 2001-12-05 2003-06-17 Fuji Electric Co Ltd 水中のリン酸計測方法と装置
ATE399212T1 (de) 2002-01-29 2008-07-15 Discoverx Inc Enzymaktivierungsprotease-assay
WO2003063693A2 (en) 2002-01-31 2003-08-07 Expressive Constructs, Inc. Method for detecting microorganisms
US20060292646A1 (en) 2002-11-26 2006-12-28 Colpas Gerard J Methods, biosensors, and kits for detecting and identifying fungi
WO2004087942A2 (en) 2003-01-31 2004-10-14 Ethicon, Inc. Method for detecting escherichia coli
DK1762626T3 (da) * 2003-09-02 2011-03-14 Systagenix Wound Man Ip Co Bv Signalamplifikation under anvendelse af et syntetisk zymogen
WO2005042771A2 (en) 2003-11-03 2005-05-12 Ethicon, Inc. Colorimetric substrates, colorimetric sensors, and methods of use

Also Published As

Publication number Publication date
CA2564426A1 (en) 2005-03-10
AU2011202044A1 (en) 2011-05-26
WO2005021780A1 (en) 2005-03-10
JP2007503833A (ja) 2007-03-01
JP4991251B2 (ja) 2012-08-01
US8039228B2 (en) 2011-10-18
ATE491806T1 (de) 2011-01-15
DE602004030623D1 (de) 2011-01-27
EP1670936A1 (en) 2006-06-21
US7566564B2 (en) 2009-07-28
US20070196881A1 (en) 2007-08-23
US20070122873A1 (en) 2007-05-31
EP1762626B1 (en) 2010-12-15
ES2357547T3 (es) 2011-04-27
AU2008203204A1 (en) 2008-08-07
PT1762626E (pt) 2011-01-28
CA2564426C (en) 2013-01-08
JP2007044052A (ja) 2007-02-22
EP1762626A1 (en) 2007-03-14
CA2537529A1 (en) 2005-03-10
AU2004269425A1 (en) 2005-03-10
JP2012120541A (ja) 2012-06-28

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