DE602004009036D1 - Verbessertes verfahren zum nachweis von proteolytischen enzymen - Google Patents
Verbessertes verfahren zum nachweis von proteolytischen enzymenInfo
- Publication number
- DE602004009036D1 DE602004009036D1 DE602004009036T DE602004009036T DE602004009036D1 DE 602004009036 D1 DE602004009036 D1 DE 602004009036D1 DE 602004009036 T DE602004009036 T DE 602004009036T DE 602004009036 T DE602004009036 T DE 602004009036T DE 602004009036 D1 DE602004009036 D1 DE 602004009036D1
- Authority
- DE
- Germany
- Prior art keywords
- detection
- improved method
- proteolytic enzymes
- modified pro
- caspases
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 108091005804 Peptidases Proteins 0.000 title abstract 3
- 102000035195 Peptidases Human genes 0.000 title abstract 2
- 238000001514 detection method Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 229940024999 proteolytic enzymes for treatment of wounds and ulcers Drugs 0.000 title 1
- 102000011727 Caspases Human genes 0.000 abstract 4
- 108010076667 Caspases Proteins 0.000 abstract 4
- 239000004365 Protease Substances 0.000 abstract 2
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 abstract 1
- 238000003556 assay Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6472—Cysteine endopeptidases (3.4.22)
- C12N9/6475—Interleukin 1-beta convertase-like enzymes (3.4.22.10; 3.4.22.36; 3.4.22.63)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03075319A EP1443116A1 (de) | 2003-01-31 | 2003-01-31 | Verbessertes Verfahren zum Nachweis von proteolytischen Enzymen |
| EP03075319 | 2003-01-31 | ||
| PCT/NL2004/000067 WO2004067768A2 (en) | 2003-01-31 | 2004-01-29 | Improved method for the detection of proteolytic enzymes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE602004009036D1 true DE602004009036D1 (de) | 2007-10-31 |
| DE602004009036T2 DE602004009036T2 (de) | 2008-06-19 |
Family
ID=32605369
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE602004009036T Expired - Lifetime DE602004009036T2 (de) | 2003-01-31 | 2004-01-29 | Verbessertes verfahren zum nachweis von proteolytischen enzymen |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US7361485B2 (de) |
| EP (2) | EP1443116A1 (de) |
| JP (1) | JP4708326B2 (de) |
| AT (1) | ATE373723T1 (de) |
| DE (1) | DE602004009036T2 (de) |
| WO (1) | WO2004067768A2 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006068469A1 (en) * | 2004-12-23 | 2006-06-29 | Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek Tno | Methods for the functional determination of mannan-binding-lectin associated serine proteases (masps) and complexes thereof |
| WO2007091881A2 (en) * | 2005-04-29 | 2007-08-16 | Leiden University Medical Center | Methods and means for detection of mycobacterium leprae infections |
| US9096886B2 (en) * | 2011-03-11 | 2015-08-04 | Merz Pharma Gmbh & Co. Kgaa | Method for the determination of botulinum neurotoxin biological activity |
| US9402876B2 (en) | 2013-11-27 | 2016-08-02 | Industrial Technology Research Institute | Method and pharmaceutical composition for hair growth |
| CA3229467A1 (en) * | 2021-09-02 | 2023-03-09 | Wei Chen | Multiplex, temporally resolved molecular signal recorder and related methods |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE226642T1 (de) * | 1994-07-07 | 2002-11-15 | Tno | Modifizierte proenzyme als substrate für proteolische enzyme |
| EP0691409B1 (de) * | 1994-07-07 | 2002-10-23 | Nederlandse Organisatie voor toegepast-natuurwetenschappelijk Onderzoek TNO | Modifizierte Proenzyme als Substrate für proteolische Enzyme |
| US6270980B1 (en) * | 1997-06-05 | 2001-08-07 | Idun Pharmaceuticals, Inc. | Rapid methods for identifying modifiers of cellular apoptosis activity |
| US6379950B1 (en) * | 1998-01-09 | 2002-04-30 | Thomas Jefferson University | Recombinant, active caspases and uses thereof |
-
2003
- 2003-01-31 EP EP03075319A patent/EP1443116A1/de not_active Withdrawn
-
2004
- 2004-01-29 JP JP2006502732A patent/JP4708326B2/ja not_active Expired - Fee Related
- 2004-01-29 US US10/543,735 patent/US7361485B2/en not_active Expired - Lifetime
- 2004-01-29 AT AT04706386T patent/ATE373723T1/de active
- 2004-01-29 EP EP04706386A patent/EP1587952B1/de not_active Expired - Lifetime
- 2004-01-29 WO PCT/NL2004/000067 patent/WO2004067768A2/en active IP Right Grant
- 2004-01-29 DE DE602004009036T patent/DE602004009036T2/de not_active Expired - Lifetime
-
2008
- 2008-02-29 US US12/074,132 patent/US20080187945A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1587952A2 (de) | 2005-10-26 |
| DE602004009036T2 (de) | 2008-06-19 |
| EP1587952B1 (de) | 2007-09-19 |
| US20080187945A1 (en) | 2008-08-07 |
| JP2006516900A (ja) | 2006-07-13 |
| JP4708326B2 (ja) | 2011-06-22 |
| US20060240406A1 (en) | 2006-10-26 |
| EP1443116A1 (de) | 2004-08-04 |
| US7361485B2 (en) | 2008-04-22 |
| WO2004067768A3 (en) | 2004-12-02 |
| ATE373723T1 (de) | 2007-10-15 |
| WO2004067768A2 (en) | 2004-08-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |