ATE438100T1 - Verfahren zum funktionellen nachweis von masps und dessen komplexen - Google Patents

Verfahren zum funktionellen nachweis von masps und dessen komplexen

Info

Publication number
ATE438100T1
ATE438100T1 AT05822941T AT05822941T ATE438100T1 AT E438100 T1 ATE438100 T1 AT E438100T1 AT 05822941 T AT05822941 T AT 05822941T AT 05822941 T AT05822941 T AT 05822941T AT E438100 T1 ATE438100 T1 AT E438100T1
Authority
AT
Austria
Prior art keywords
gly
sample
activity
determining
masps
Prior art date
Application number
AT05822941T
Other languages
English (en)
Inventor
Johan Verheijen
Lent Natascha Van
Johannes Lindeman
Mohamed Daha
Johanna Roos
Jan Hanemaaijer
Original Assignee
Tno
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tno filed Critical Tno
Application granted granted Critical
Publication of ATE438100T1 publication Critical patent/ATE438100T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2337/00—N-linked chromogens for determinations of peptidases and proteinases
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
    • G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
    • G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
    • G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
    • G01N2333/96433—Serine endopeptidases (3.4.21)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Rehabilitation Therapy (AREA)
  • General Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
AT05822941T 2004-12-23 2005-12-19 Verfahren zum funktionellen nachweis von masps und dessen komplexen ATE438100T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04078507 2004-12-23
PCT/NL2005/000874 WO2006068469A1 (en) 2004-12-23 2005-12-19 Methods for the functional determination of mannan-binding-lectin associated serine proteases (masps) and complexes thereof

Publications (1)

Publication Number Publication Date
ATE438100T1 true ATE438100T1 (de) 2009-08-15

Family

ID=34928774

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05822941T ATE438100T1 (de) 2004-12-23 2005-12-19 Verfahren zum funktionellen nachweis von masps und dessen komplexen

Country Status (7)

Country Link
US (1) US7811771B2 (de)
EP (1) EP1828775B1 (de)
JP (1) JP5014149B2 (de)
AT (1) ATE438100T1 (de)
DE (1) DE602005015756D1 (de)
DK (1) DK1828775T3 (de)
WO (1) WO2006068469A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108220389A (zh) * 2017-12-25 2018-06-29 丽珠集团丽珠制药厂 尿激酶效价的测定方法
KR20210110848A (ko) 2018-12-28 2021-09-09 카탈리스트 바이오사이언시즈, 인코포레이티드 변형된 유로키나제 유형 플라스미노겐 활성제 폴리펩타이드 및 사용 방법
US11613744B2 (en) 2018-12-28 2023-03-28 Vertex Pharmaceuticals Incorporated Modified urokinase-type plasminogen activator polypeptides and methods of use

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0691409B1 (de) * 1994-07-07 2002-10-23 Nederlandse Organisatie voor toegepast-natuurwetenschappelijk Onderzoek TNO Modifizierte Proenzyme als Substrate für proteolische Enzyme
DK1303591T3 (da) * 2000-07-13 2009-11-02 Helion Biotech Aps MASP-2, et komplementfikserende enzym, og anvendelser af det
US20050118603A1 (en) * 2002-10-11 2005-06-02 Ahram Biosystems Inc. Target detection system having a conformationally sensitive probe comprising a nucleic acid based signal transducer
EP1443116A1 (de) * 2003-01-31 2004-08-04 Nederlandse Organisatie voor toegepast-natuurwetenschappelijk Onderzoek TNO Verbessertes Verfahren zum Nachweis von proteolytischen Enzymen

Also Published As

Publication number Publication date
US7811771B2 (en) 2010-10-12
WO2006068469A1 (en) 2006-06-29
DK1828775T3 (da) 2009-11-30
EP1828775B1 (de) 2009-07-29
JP2008525016A (ja) 2008-07-17
WO2006068469A8 (en) 2007-08-02
JP5014149B2 (ja) 2012-08-29
DE602005015756D1 (de) 2009-09-10
EP1828775A1 (de) 2007-09-05
US20080286803A1 (en) 2008-11-20

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