DK175898B1 - Fremgangsmåde til at udtrykke ikke-gærprotein i en gærvært og transformeret gærvært samt anvendelsen af en transformeret gær til fremstilling af gærværten - Google Patents
Fremgangsmåde til at udtrykke ikke-gærprotein i en gærvært og transformeret gærvært samt anvendelsen af en transformeret gær til fremstilling af gærværten Download PDFInfo
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- DK175898B1 DK175898B1 DK198902215A DK221589A DK175898B1 DK 175898 B1 DK175898 B1 DK 175898B1 DK 198902215 A DK198902215 A DK 198902215A DK 221589 A DK221589 A DK 221589A DK 175898 B1 DK175898 B1 DK 175898B1
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
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- C—CHEMISTRY; METALLURGY
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- C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19086888A | 1988-05-06 | 1988-05-06 | |
| US19086888 | 1988-05-06 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK221589D0 DK221589D0 (da) | 1989-05-05 |
| DK221589A DK221589A (da) | 1989-11-07 |
| DK175898B1 true DK175898B1 (da) | 2005-05-30 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK198902215A DK175898B1 (da) | 1988-05-06 | 1989-05-05 | Fremgangsmåde til at udtrykke ikke-gærprotein i en gærvært og transformeret gærvært samt anvendelsen af en transformeret gær til fremstilling af gærværten |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6183985B1 (de) |
| EP (1) | EP0340986B1 (de) |
| JP (4) | JP3074174B2 (de) |
| AT (1) | ATE123521T1 (de) |
| CA (1) | CA1324969C (de) |
| DE (1) | DE68922932T2 (de) |
| DK (1) | DK175898B1 (de) |
| ES (1) | ES2072900T3 (de) |
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| DK0801682T3 (da) | 1995-02-09 | 2002-02-18 | Aventis Pharma Gmbh | Fremgangsmåde til fremstilling af proteiner |
| DE19544233A1 (de) * | 1995-11-28 | 1997-06-05 | Hoechst Ag | Verfahren zur Nutzung des Hefe-ADH II-Promotorsystems zur biotechnologischen Produktion heterologer Proteine in hohen Ausbeuten |
| WO2003027280A1 (fr) * | 2001-09-20 | 2003-04-03 | Toyota Jidosha Kabushiki Kaisha | Systeme de surexpression genique |
| KR20070007086A (ko) | 2004-02-02 | 2007-01-12 | 암브룩스, 인코포레이티드 | 변형된 인간의 4 개의 나선형 다발 폴리펩티드 및 이의용도 |
| BRPI0512235A (pt) * | 2004-06-18 | 2008-02-19 | Ambrx Inc | polipeptìdeos ligadores de antìgenos e seus usos |
| CA2569381A1 (en) * | 2004-07-21 | 2006-08-31 | Ambrx, Inc. | Biosynthetic polypeptides utilizing non-naturally encoded amino acids |
| CA2594557C (en) * | 2004-12-22 | 2016-04-26 | Ambrx, Inc. | Modified human growth hormone |
| AU2005319518B2 (en) * | 2004-12-22 | 2010-09-09 | Ambrx, Inc. | Compositions of aminoacyl-tRNA synthetase and uses thereof |
| NZ555386A (en) | 2004-12-22 | 2011-01-28 | Ambrx Inc | Formulations of human growth hormone comprising a non-naturally encoded amino acid |
| GB2438760A (en) * | 2004-12-22 | 2007-12-05 | Ambrx Inc | Methods for expression and purification of recombinant human growth hormone |
| CA3005835C (en) | 2004-12-22 | 2023-01-31 | Ambrx, Inc. | Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides |
| SG165353A1 (en) * | 2005-06-03 | 2010-10-28 | Ambrx Inc | Improved human interferon molecules and their uses |
| DE102005029170A1 (de) * | 2005-06-23 | 2006-12-28 | Consortium für elektrochemische Industrie GmbH | System zur Genexpression in Hefen der Gattung Sporidiobolus |
| CN102703446B (zh) | 2005-08-18 | 2014-05-28 | Ambrx公司 | tRNA组合物和其用途 |
| NZ567234A (en) * | 2005-11-08 | 2011-09-30 | Ambrx Inc | Accelerants for the modification of non-natural amino acids and non-natural amino acid polypeptides |
| WO2007059312A2 (en) | 2005-11-16 | 2007-05-24 | Ambrx, Inc. | Methods and compositions comprising non-natural amino acids |
| CA2630220C (en) | 2005-11-22 | 2020-10-13 | Doris Coit | Norovirus and sapovirus antigens |
| US9133495B2 (en) * | 2006-09-08 | 2015-09-15 | Ambrx, Inc. | Hybrid suppressor tRNA for vertebrate cells |
| CN101511856B (zh) * | 2006-09-08 | 2016-01-20 | Ambrx公司 | 脊椎动物细胞中抑制因子trna的转录 |
| AU2007292903B2 (en) * | 2006-09-08 | 2012-03-29 | Ambrx, Inc. | Modified human plasma polypeptide or Fc scaffolds and their uses |
| EP2106447B1 (de) * | 2007-01-26 | 2013-04-17 | Novozymes A/S | Verfahren zur methanolunabhängigen einführung methanolinduzierbarer promotoren in pichia |
| KR20140012199A (ko) | 2007-03-30 | 2014-01-29 | 암브룩스, 인코포레이티드 | 변형된 ｆｇｆ-21 폴리펩티드 및 그 용도 |
| NZ580686A (en) | 2007-05-02 | 2012-11-30 | Ambrx Inc | Modified interferon beta polypeptides and their uses |
| ES2632504T3 (es) | 2007-11-20 | 2017-09-13 | Ambrx, Inc. | Polipéptidos de insulina modificados y sus usos |
| NZ602170A (en) | 2008-02-08 | 2014-03-28 | Ambrx Inc | Modified leptin polypeptides and their uses |
| EP2300615A2 (de) * | 2008-07-11 | 2011-03-30 | Novozymes A/S | Das-promotervarianten aus pichia pastoris |
| NZ600382A (en) | 2008-07-23 | 2013-11-29 | Ambrx Inc | Modified bovine G-CSF polypeptides and their uses |
| WO2010036964A2 (en) | 2008-09-26 | 2010-04-01 | Ambrx Inc. | Modified animal erythropoietin polypeptides and their uses |
| ES2660000T3 (es) | 2008-09-26 | 2018-03-20 | Ambrx, Inc. | Vacunas y microorganismos dependientes de la replicación de aminoácidos no naturales |
| EP2805965A1 (de) | 2009-12-21 | 2014-11-26 | Ambrx, Inc. | Modifizierte Schweine-Somatotropin-Polypeptide und deren Verwendungen |
| CN102753573A (zh) | 2009-12-21 | 2012-10-24 | Ambrx公司 | 经过修饰的牛促生长素多肽和其用途 |
| EP2591097A1 (de) | 2010-07-06 | 2013-05-15 | Novartis AG | Immunogene zusammensetzungen aus norovirus und verfahren |
| PL2605789T3 (pl) | 2010-08-17 | 2019-11-29 | Ambrx Inc | Zmodyfikowane polipeptydy relaksyny i ich zastosowania |
| US9567386B2 (en) | 2010-08-17 | 2017-02-14 | Ambrx, Inc. | Therapeutic uses of modified relaxin polypeptides |
| TWI480288B (zh) | 2010-09-23 | 2015-04-11 | Lilly Co Eli | 牛顆粒細胞群落刺激因子及其變體之調配物 |
| CA2965502A1 (en) | 2014-10-24 | 2016-04-28 | Bristol-Myers Squibb Company | Modified fgf-21 polypeptides and uses thereof |
| MX2019008449A (es) | 2017-02-08 | 2019-09-09 | Bristol Myers Squibb Co | Polipetidos de relaxina modificada que comprenden un mejorador farmacocinetico y sus usos. |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4880734A (en) * | 1984-05-11 | 1989-11-14 | Chiron Corporation | Eukaryotic regulatable transcription |
| EP0196056B1 (de) * | 1985-03-28 | 1991-05-22 | Chiron Corporation | Expression durch Verwendung von Fusionsgenen für Proteinproduktion |
| EP0234871A3 (de) | 1986-02-28 | 1988-10-12 | Merck & Co. Inc. | Regulierbare Expression rekombinanter Proteine in Hefe |
| US5068185A (en) | 1986-07-10 | 1991-11-26 | Merck & Co., Inc. | Trains of yeast for the expression of heterologous genes |
-
1989
- 1989-04-21 CA CA000597461A patent/CA1324969C/en not_active Expired - Lifetime
- 1989-04-28 EP EP89304297A patent/EP0340986B1/de not_active Expired - Lifetime
- 1989-04-28 DE DE68922932T patent/DE68922932T2/de not_active Expired - Lifetime
- 1989-04-28 ES ES89304297T patent/ES2072900T3/es not_active Expired - Lifetime
- 1989-04-28 AT AT89304297T patent/ATE123521T1/de not_active IP Right Cessation
- 1989-05-02 JP JP01113585A patent/JP3074174B2/ja not_active Expired - Lifetime
- 1989-05-05 DK DK198902215A patent/DK175898B1/da not_active IP Right Cessation
-
1995
- 1995-03-01 US US08/397,553 patent/US6183985B1/en not_active Expired - Lifetime
-
2000
- 2000-01-12 JP JP2000004098A patent/JP3484386B2/ja not_active Expired - Lifetime
-
2002
- 2002-08-14 JP JP2002236635A patent/JP3561513B2/ja not_active Expired - Fee Related
-
2003
- 2003-12-10 JP JP2003412625A patent/JP2004081222A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| EP0340986B1 (de) | 1995-06-07 |
| JP3484386B2 (ja) | 2004-01-06 |
| JP3561513B2 (ja) | 2004-09-02 |
| JPH02104291A (ja) | 1990-04-17 |
| DE68922932T2 (de) | 1995-10-19 |
| ES2072900T3 (es) | 1995-08-01 |
| DK221589D0 (da) | 1989-05-05 |
| CA1324969C (en) | 1993-12-07 |
| DK221589A (da) | 1989-11-07 |
| JP2000300277A (ja) | 2000-10-31 |
| JP2003116525A (ja) | 2003-04-22 |
| EP0340986A3 (de) | 1991-07-31 |
| US6183985B1 (en) | 2001-02-06 |
| JP2004081222A (ja) | 2004-03-18 |
| ATE123521T1 (de) | 1995-06-15 |
| JP3074174B2 (ja) | 2000-08-07 |
| DE68922932D1 (de) | 1995-07-13 |
| EP0340986A2 (de) | 1989-11-08 |
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