DK1757276T3 - Fremgangsmåde til fremstilling af nano- og mikrokapsler af edderkoppesilkeprotein - Google Patents

Fremgangsmåde til fremstilling af nano- og mikrokapsler af edderkoppesilkeprotein

Info

Publication number
DK1757276T3
DK1757276T3 DK05016712T DK05016712T DK1757276T3 DK 1757276 T3 DK1757276 T3 DK 1757276T3 DK 05016712 T DK05016712 T DK 05016712T DK 05016712 T DK05016712 T DK 05016712T DK 1757276 T3 DK1757276 T3 DK 1757276T3
Authority
DK
Denmark
Prior art keywords
microcapsules
nano
spider silk
preparation
silk protein
Prior art date
Application number
DK05016712T
Other languages
Danish (da)
English (en)
Inventor
Thomas Scheibel
Andreas Bausch
Daniel Huemmerich
Kevin Hermanson
Original Assignee
Univ Muenchen Tech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Muenchen Tech filed Critical Univ Muenchen Tech
Application granted granted Critical
Publication of DK1757276T3 publication Critical patent/DK1757276T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/11—Encapsulated compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5052—Proteins, e.g. albumin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5169—Proteins, e.g. albumin, gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5192—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43563—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41—Particular ingredients further characterized by their size
    • A61K2800/412—Microsized, i.e. having sizes between 0.1 and 100 microns
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41—Particular ingredients further characterized by their size
    • A61K2800/413—Nanosized, i.e. having sizes below 100 nm
DK05016712T 2005-08-01 2005-08-01 Fremgangsmåde til fremstilling af nano- og mikrokapsler af edderkoppesilkeprotein DK1757276T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP05016712A EP1757276B1 (de) 2005-08-01 2005-08-01 Prozess zur Herstellung von Nano- und Mikrokapseln aus Spinnenseidenprotein

Publications (1)

Publication Number Publication Date
DK1757276T3 true DK1757276T3 (da) 2008-02-04

Family

ID=35197006

Family Applications (1)

Application Number Title Priority Date Filing Date
DK05016712T DK1757276T3 (da) 2005-08-01 2005-08-01 Fremgangsmåde til fremstilling af nano- og mikrokapsler af edderkoppesilkeprotein

Country Status (12)

Country Link
US (2) US8372436B2 (de)
EP (1) EP1757276B1 (de)
JP (1) JP5129746B2 (de)
CN (1) CN101309676B (de)
AT (1) ATE374018T1 (de)
CA (1) CA2617530C (de)
DE (1) DE602005002654T2 (de)
DK (1) DK1757276T3 (de)
ES (1) ES2294606T3 (de)
PL (1) PL1757276T3 (de)
PT (1) PT1757276E (de)
WO (1) WO2007014755A1 (de)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6092337A (ja) * 1983-10-26 1985-05-23 Sekisui Plastics Co Ltd 発泡フエノ−ル樹脂成形物の製造方法
EP1979055A2 (de) * 2006-01-20 2008-10-15 Basf Se Verwendung von protein-microbeads in der kosmetik
WO2008071226A1 (en) * 2006-12-11 2008-06-19 Medizinische Hochschule Hannover Implant of cross-linked spider silk threads
JP2008201767A (ja) * 2007-01-24 2008-09-04 Fujifilm Corp 頭髪用組成物
US20080175807A1 (en) 2007-01-24 2008-07-24 Fujifilm Corporation Composition for hair
JP2008255020A (ja) * 2007-04-02 2008-10-23 Fujifilm Corp 抗老化皮膚外用剤
WO2008130624A1 (en) * 2007-04-18 2008-10-30 The Regents Of The University Of California Protein-modified nano-droplets, compositions and methods of production
EP2164864B1 (de) * 2007-06-20 2014-12-03 Basf Se Synthetische repetitive proteine, deren herstellung und verwendung
EP2506837B1 (de) 2009-11-30 2020-07-01 Amsilk GmbH Spinnenseidenpartikel zur kontrollierten und verzögerten freisetzung von substanzen
US10500156B2 (en) 2010-03-24 2019-12-10 Northeastern University Multi-compartmental macrophage delivery
KR101494711B1 (ko) 2011-11-04 2015-02-26 동아대학교 산학협력단 산왕거미 유래 메이저 엠풀레이트 스피드로인 단백질의 반복적인 ｃ-말단 영역의 폴리펩티드 서열 및 이를 코딩하는 염기서열
WO2014012105A1 (en) * 2012-07-13 2014-01-16 Tufts University Encapsulation of immiscible phases in silk fibroin biomaterials
US20150164117A1 (en) * 2012-07-13 2015-06-18 Tufts University Encapsulation of fragrance and/or flavors in silk fibroin biomaterials
JP6450680B2 (ja) * 2012-09-06 2019-01-09 アーエムシルク ゲーエムベーハー 高靱性シルク繊維を作製する方法
CA2905365C (en) 2013-03-15 2021-03-23 Banner Life Sciences Llc Silk-based capsules
GB201415681D0 (en) 2014-09-04 2014-10-22 Cambridge Entpr Ltd And President And Fellows Of Harvard College Protien Capsules
DE102014218502A1 (de) 2014-09-16 2016-03-17 Henkel Ag & Co. Kgaa Proteinhaltiges Reinigungsmittel
DE102014218503A1 (de) 2014-09-16 2016-03-17 Henkel Ag & Co. Kgaa Proteinhaltiges Waschmittel
DE102014218507A1 (de) 2014-09-16 2016-03-17 Henkel Ag & Co. Kgaa Spinnenseidenproteine als Enzymstabilisatoren
KR20170099920A (ko) 2014-12-02 2017-09-01 실크 테라퓨틱스, 인코퍼레이티드 실크 성능 의류와 제품들 및 이의 제조 방법
CN104927777B (zh) * 2015-06-02 2018-04-24 清华大学深圳研究生院 相变储能微胶囊制备方法及应用
CA2992462A1 (en) 2015-07-14 2017-01-19 Silk Therapeutics, Inc. Silk performance apparel and products and methods of preparing the same
EP3475296A1 (de) 2016-06-22 2019-05-01 AMSilk GmbH Artikel mit einem seidenpolypeptid zur antigenabgabe
DE102016222480B4 (de) 2016-11-16 2020-02-13 Adidas Ag Bekleidungsstück, das Spinnenseide aufweist oder Schuh, der Spinnenseide aufweist, und ein entsprechendes Herstellungsverfahren
WO2019067745A1 (en) 2017-09-27 2019-04-04 Silk, Inc. SILK-COATED FABRICS, PRODUCTS AND PREPARATION METHODS THEREFOR
WO2020035361A1 (en) 2018-08-17 2020-02-20 Amsilk Gmbh Use of a structural polypeptide for plant coating
CN109329910A (zh) * 2018-09-28 2019-02-15 青岛大学 一种蜘蛛丝组合物口服液的制备方法
MX2022000463A (es) * 2019-07-12 2022-02-03 Bolt Threads Inc Formulaciones de extrusado recombinante de seda de araña.
CN111214385B (zh) * 2020-03-13 2022-05-17 珀莱雅化妆品股份有限公司 一种负载皮肤营养剂的纳米粒乳液及其制备方法
WO2022123996A1 (ja) 2020-12-07 2022-06-16 山下マテリアル株式会社 フレキシブル多層基板及びその製造方法
CN116635011A (zh) * 2020-12-24 2023-08-22 国立大学法人筑波大学 丝心蛋白微球及其制造方法
WO2023152202A1 (en) 2022-02-10 2023-08-17 Amsilk Gmbh Gradient printing reservoir and printing method

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2683159B1 (fr) * 1991-10-31 1994-02-25 Coletica Procede de fabrication de nanocapsules a paroi a base de proteines reticulees; nanocapsules ainsi obtenues et compositions cosmetiques, pharmaceutiques et alimentaires en comportant application.
JP3094181B2 (ja) * 1992-04-09 2000-10-03 清 山内 再生天然ケラチンを壁材とするマイクロカプセル及びその製造方法
JPH08511426A (ja) 1993-06-15 1996-12-03 イー・アイ・デユポン・ドウ・ヌムール・アンド・カンパニー 新規の組換え産生性クモシルクアナログ
JPH08268905A (ja) 1995-03-31 1996-10-15 Takayuki Nagashima コロイド状絹フィブロイン及びそれを含有する組成物
JPH08295697A (ja) 1995-04-26 1996-11-12 Kanebo Ltd 高濃度絹フィブロイン水溶液の製造方法
JP2997758B2 (ja) 1996-01-23 2000-01-11 農林水産省蚕糸・昆虫農業技術研究所長 創傷被覆材
JP3537297B2 (ja) 1996-08-15 2004-06-14 聖治 寺内 フィブロイン流動体及びその製造方法
FR2774588B1 (fr) * 1998-02-11 2000-05-05 Oreal Composition cosmetique ou dermatologique contenant au moins une proteine de soie d'arachnides naturelle, recombinante ou un analogue
JP2972877B1 (ja) * 1998-07-24 1999-11-08 農林水産省蚕糸・昆虫農業技術研究所長 高分子素材のドープ、高分子素材からなるマイクロビーズおよびそのビーズの製造方法
JP2001163899A (ja) 1999-12-09 2001-06-19 Natl Inst Of Sericultural & Entomological Science 機能性絹フィブロインの製造方法とその利用
US6608242B1 (en) 2000-05-25 2003-08-19 E. I. Du Pont De Nemours And Company Production of silk-like proteins in plants
WO2003045336A1 (fr) * 2001-11-29 2003-06-05 National Institute Of Agrobiological Sciences Emulsifiant et procede d'elaboration correspondant
US20040132978A1 (en) * 2002-11-12 2004-07-08 Fahnestock Stephen R. Method for purifying and recovering silk proteins in soluble form and uses thereof
CN1288193C (zh) * 2004-03-10 2006-12-06 复旦大学 蚕丝蛋白纳米微球及其制备方法
WO2005123114A2 (en) 2004-06-11 2005-12-29 Trustees Of Tufts College Silk-based drug delivery system

Also Published As

Publication number Publication date
JP5129746B2 (ja) 2013-01-30
JP2009502492A (ja) 2009-01-29
PL1757276T3 (pl) 2008-02-29
DE602005002654T2 (de) 2008-06-19
ATE374018T1 (de) 2007-10-15
PT1757276E (pt) 2008-01-02
US20100056438A1 (en) 2010-03-04
US20130136779A1 (en) 2013-05-30
EP1757276A1 (de) 2007-02-28
CN101309676B (zh) 2012-02-29
EP1757276B1 (de) 2007-09-26
US8729238B2 (en) 2014-05-20
CN101309676A (zh) 2008-11-19
DE602005002654D1 (de) 2007-11-08
WO2007014755A1 (en) 2007-02-08
ES2294606T3 (es) 2008-04-01
US8372436B2 (en) 2013-02-12
CA2617530C (en) 2013-10-01
CA2617530A1 (en) 2007-02-08

Similar Documents

Publication Publication Date Title
DK1757276T3 (da) Fremgangsmåde til fremstilling af nano- og mikrokapsler af edderkoppesilkeprotein
EA201490132A1 (ru) Противовирусные соединения
CY1109568T1 (el) Ενωσεις βενζο(d)ισοξαζολ-3-υλαμινης και η χρησιμοποιηση τους σαν προσδεματα υποδοχεα βανιλλοειδων
MXPA05012362A (es) Yodopirazolilcarboxanilidas.
IL265947A (en) Preparation of stansoporfin with a high degree of purification on a large scale
ME01714B (me) KRISTALISAN POLIETILEN TEREFTALAT, KOJI SADRŽI SlLICIJUM, I POSTUPAK ZA NJEGOVO DOBIJANJE
DE60307268D1 (de) Pestizide pyridincarbonsäureamidderivate
DK1519944T3 (da) Fremgangsmåder til fremstilling af fibrinogen
WO2009053446A3 (en) Pregabalin intermediates and process for preparing them and pregabalin
NO20081617L (no) Metoder for fremstilling av Glutaminsyrederivater
ATE518828T1 (de) Ein-topf-verfahren zur herstellung von 3-(2,2,2- trimethylhydrazinium)propionat-dihydrat
DK2060568T3 (da) Polymorfer af enantiomerisk ren erdostein
WO2009141079A8 (de) Neue [f-18]-markierte l-glutaminsäure- und l-glutaminderivative (ii), ihre verwendung sowie verfahren zu ihrer herstellung
ATE464289T1 (de) Neues verfahren zur herstellung von thoc
NO20084839L (no) Metoder for fremstilling av glutaminsyrederivater og melomprodukter
NO20061290L (no) Nye forbindelser
NO20076139L (no) Fremgangsmate for a fremstille blekeaktivatorer
EA200900257A1 (ru) Полиморфные формы сульфатов зипразидона
DE602006020760D1 (de) Verfahren zur herstellung von perindoprilerbumin
DE502006005580D1 (de) Verfahren zur herstellung von optisch aktiven 3-phenylpropionsäurederivaten und folgeprodukte davon
DE602006020238D1 (de) Optisch aktiven Cyclopentenonen zur Herstellung von Prostaglandinen
NO20064273L (no) Fremgangsmate for semisyntese av deserpidin
BRPI0409332A (pt) processo de preparação do 4,10beta-diacetóxi-2alfa-benzoilóxi-5beta, 20-epóxi-1,13alfa-dihidróxi-9-oxo-19-norciclopropa[g] tax-11-eno
DE602008005002D1 (de) Neues verfahren zur herstellung von timberon
TW200724523A (en) The manufacturing method of prostaglandin F derivatives and the novel intermediates thereof