DK175489B1 - Immunogent konjugat og fremstilling deraf samt vaccine indeholdende dette og fremgangsmåde til fremstilling af et kapselpolymerfragment - Google Patents

Immunogent konjugat og fremstilling deraf samt vaccine indeholdende dette og fremgangsmåde til fremstilling af et kapselpolymerfragment Download PDF

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Publication number
DK175489B1
DK175489B1 DK198800025A DK2588A DK175489B1 DK 175489 B1 DK175489 B1 DK 175489B1 DK 198800025 A DK198800025 A DK 198800025A DK 2588 A DK2588 A DK 2588A DK 175489 B1 DK175489 B1 DK 175489B1
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Prior art keywords
toxoid
toxin
immunogenic conjugate
conjugate
immunogenic
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DK198800025A
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Danish (da)
English (en)
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DK2588D0 (da
DK2588A (da
Inventor
Porter W Anderson
Ronald John Eby
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Univ Rochester
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Publication of DK2588D0 publication Critical patent/DK2588D0/da
Publication of DK2588A publication Critical patent/DK2588A/da
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Publication of DK175489B1 publication Critical patent/DK175489B1/da

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/102—Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/385—Haptens or antigens, bound to carriers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/646—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/831—Drug, bio-affecting and body treating compositions involving capsular polysaccharide of bacterium, e.g. polyribosyl ribitol phosphate
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/832—Drug, bio-affecting and body treating compositions involving bacterial toxin that has modified amino acid sequence

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK198800025A 1986-05-05 1988-01-05 Immunogent konjugat og fremstilling deraf samt vaccine indeholdende dette og fremgangsmåde til fremstilling af et kapselpolymerfragment DK175489B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US06/859,975 US4902506A (en) 1983-07-05 1986-05-05 Immunogenic conjugates
US85997586 1986-05-05
US8701020 1987-05-01
PCT/US1987/001020 WO1987006838A1 (fr) 1986-05-05 1987-05-01 Conjugues immunogeniques

Publications (3)

Publication Number Publication Date
DK2588D0 DK2588D0 (da) 1988-01-05
DK2588A DK2588A (da) 1988-01-05
DK175489B1 true DK175489B1 (da) 2004-11-08

Family

ID=25332206

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198800025A DK175489B1 (da) 1986-05-05 1988-01-05 Immunogent konjugat og fremstilling deraf samt vaccine indeholdende dette og fremgangsmåde til fremstilling af et kapselpolymerfragment

Country Status (14)

Country Link
US (1) US4902506A (fr)
EP (1) EP0245045B1 (fr)
JP (2) JP2559438B2 (fr)
AT (1) ATE96676T1 (fr)
AU (1) AU601742B2 (fr)
CA (1) CA1276109C (fr)
DE (3) DE10199036I1 (fr)
DK (1) DK175489B1 (fr)
ES (1) ES2059372T3 (fr)
HK (1) HK1003326A1 (fr)
IE (1) IE60897B1 (fr)
LU (2) LU90808I2 (fr)
NL (2) NL300051I2 (fr)
WO (1) WO1987006838A1 (fr)

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DK2588D0 (da) 1988-01-05
NL300051I1 (nl) 2001-10-01
JP2736248B2 (ja) 1998-04-02
IE871185L (en) 1987-11-05
JPH08283282A (ja) 1996-10-29
US4902506A (en) 1990-02-20
WO1987006838A1 (fr) 1987-11-19
IE60897B1 (en) 1994-08-24
EP0245045B1 (fr) 1993-11-03
AU7393587A (en) 1987-12-01
DE10199037I1 (de) 2001-11-22
DE3787995T2 (de) 1994-05-19
HK1003326A1 (en) 1998-10-23
AU601742B2 (en) 1990-09-20
CA1276109C (fr) 1990-11-13
NL300051I2 (nl) 2002-07-01
DE10199036I1 (de) 2002-01-10
LU90808I2 (fr) 2001-09-25
ES2059372T3 (es) 1994-11-16
LU90809I2 (fr) 2001-09-25
DK2588A (da) 1988-01-05
NL300052I1 (nl) 2001-10-01
EP0245045A2 (fr) 1987-11-11
DE3787995D1 (de) 1993-12-09
JP2559438B2 (ja) 1996-12-04
EP0245045A3 (en) 1989-04-26
ATE96676T1 (de) 1993-11-15
JPH01500036A (ja) 1989-01-12

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