DK175208B1 - Fremgangsmåde til fremstilling af et findelt fast stof - Google Patents
Fremgangsmåde til fremstilling af et findelt fast stof Download PDFInfo
- Publication number
- DK175208B1 DK175208B1 DK199100590A DK59091A DK175208B1 DK 175208 B1 DK175208 B1 DK 175208B1 DK 199100590 A DK199100590 A DK 199100590A DK 59091 A DK59091 A DK 59091A DK 175208 B1 DK175208 B1 DK 175208B1
- Authority
- DK
- Denmark
- Prior art keywords
- solvent
- solid
- process according
- liquid carrier
- solution
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/12—Powders or granules
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
- B01F23/04—Specific aggregation state of one or more of the phases to be mixed
- B01F23/043—Mixing fluids or with fluids in a supercritical state, in supercritical conditions or variable density fluids
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
- B01F23/09—Mixing systems, i.e. flow charts or diagrams for components having more than two different of undetermined agglomeration states, e.g. supercritical states
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
- B01F23/40—Mixing liquids with liquids; Emulsifying
- B01F23/48—Mixing liquids with liquids; Emulsifying characterised by the nature of the liquids
- B01F23/481—Mixing liquids with liquids; Emulsifying characterised by the nature of the liquids using liquefied or cryogenic gases
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F2215/00—Auxiliary or complementary information in relation with mixing
- B01F2215/04—Technical information in relation with mixing
- B01F2215/0404—Technical information in relation with mixing theories or general explanations of phenomena associated with mixing or generalizations of a concept by comparison of equivalent methods
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
- B01F23/20—Mixing gases with liquids
- B01F23/21—Mixing gases with liquids by introducing liquids into gaseous media
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US25384988A | 1988-10-05 | 1988-10-05 | |
US25384988 | 1988-10-05 | ||
PCT/US1989/003783 WO1990003782A2 (fr) | 1988-10-05 | 1989-09-06 | Poudres cristallines solides finement divisees par une precipitation dans un anti-solvant |
US8903783 | 1989-09-06 |
Publications (3)
Publication Number | Publication Date |
---|---|
DK59091D0 DK59091D0 (da) | 1991-04-03 |
DK59091A DK59091A (da) | 1991-04-03 |
DK175208B1 true DK175208B1 (da) | 2004-07-12 |
Family
ID=22961959
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK199100590A DK175208B1 (da) | 1988-10-05 | 1991-04-03 | Fremgangsmåde til fremstilling af et findelt fast stof |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP0437451B1 (fr) |
JP (1) | JP2843857B2 (fr) |
KR (1) | KR0132576B1 (fr) |
AU (1) | AU624421B2 (fr) |
CA (1) | CA1338106C (fr) |
DE (1) | DE68907062T2 (fr) |
DK (1) | DK175208B1 (fr) |
HK (1) | HK89396A (fr) |
HU (1) | HU209603B (fr) |
WO (1) | WO1990003782A2 (fr) |
Families Citing this family (52)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5360478A (en) * | 1989-10-16 | 1994-11-01 | Phasex Corporation | Gas anti-solvent recrystallization process |
US6063910A (en) * | 1991-11-14 | 2000-05-16 | The Trustees Of Princeton University | Preparation of protein microparticles by supercritical fluid precipitation |
US5639441A (en) * | 1992-03-06 | 1997-06-17 | Board Of Regents Of University Of Colorado | Methods for fine particle formation |
US5301664A (en) * | 1992-03-06 | 1994-04-12 | Sievers Robert E | Methods and apparatus for drug delivery using supercritical solutions |
US5389263A (en) * | 1992-05-20 | 1995-02-14 | Phasex Corporation | Gas anti-solvent recrystallization and application for the separation and subsequent processing of RDX and HMX |
EP0868942A1 (fr) | 1993-11-08 | 1998-10-07 | The Gillette Company | Procédé de formation de particules à l'aide d'un fluide supercritique et particules d'aérogel ainsi formées |
IT1265473B1 (it) * | 1993-12-30 | 1996-11-22 | Otefal Srl | Procedimento per la produzione di polveri a granulometria controllata e prodotto in polvere cosi' ottenuto |
AT401871B (de) * | 1994-01-28 | 1996-12-27 | Gebro Broschek Gmbh | Verfahren zur herstellung von s(+)-ibuprofen- partikeln mit verbesserten fliesseigenschaften und deren verwendung zur arzneimittelherstellung |
GB9413202D0 (en) * | 1994-06-30 | 1994-08-24 | Univ Bradford | Method and apparatus for the formation of particles |
WO1996029998A1 (fr) * | 1995-03-28 | 1996-10-03 | Fidia Advanced Biopolymers S.R.L. | Nanospheres contenant un polysaccharidique biocompatible |
SE9501384D0 (sv) * | 1995-04-13 | 1995-04-13 | Astra Ab | Process for the preparation of respirable particles |
US5803966A (en) * | 1995-11-01 | 1998-09-08 | Alcon Laboratories, Inc. | Process for sizing prednisolone acetate using a supercritical fluid anti-solvent |
US5728315A (en) * | 1996-05-01 | 1998-03-17 | Alliedsignal Inc. | Azeotrope-like compositions of trifluoromethane, carbon dioxide, ethane and hexafluoroethane |
FR2753639B1 (fr) † | 1996-09-25 | 1998-12-11 | Procede de preparation de microcapsules de matieres actives enrobees par un polymere et nouvelles microcapsules notamment obtenues selon le procede | |
AU5374398A (en) * | 1996-12-17 | 1998-07-15 | Cordant Technologies, Inc. | Salting-out process of crystallizing 2,4,6,8,10,12-hexanitro-2,4,6,8,10,12-hexaazatetracyclo (5.5.0.05,903,11)-dodecane |
SE9701956D0 (sv) | 1997-05-23 | 1997-05-23 | Astra Ab | New composition of matter |
US6221153B1 (en) * | 1998-06-09 | 2001-04-24 | Trevor Percival Castor | Method for producing large crystals of complex molecules |
SE9804003D0 (sv) * | 1998-11-23 | 1998-11-23 | Astra Ab | A method of producing drug particles |
GB9828721D0 (en) * | 1998-12-24 | 1999-02-17 | Glaxo Group Ltd | Novel apparatus and process |
SE9901667D0 (sv) | 1999-05-07 | 1999-05-07 | Astra Ab | Method and device for forming particles |
GB9915975D0 (en) | 1999-07-07 | 1999-09-08 | Bradford Particle Design Ltd | Method for the formation of particles |
US6884911B2 (en) * | 2000-03-03 | 2005-04-26 | Boehringer Ingelheim Pharmaceuticals, Inc. | Material processing by repeated solvent expansion-contraction |
CH694686A5 (it) | 2000-03-04 | 2005-06-15 | Eco2 Sa | Prodotto di micronizzazione di sostanze farmaceutiche. |
US6620351B2 (en) | 2000-05-24 | 2003-09-16 | Auburn University | Method of forming nanoparticles and microparticles of controllable size using supercritical fluids with enhanced mass transfer |
ES2170008B1 (es) * | 2000-08-25 | 2003-05-01 | Soc Es Carburos Metalicos Sa | Procedimiento para la precipitacion de particulas solidas finamente divididas. |
GB0027357D0 (en) | 2000-11-09 | 2000-12-27 | Bradford Particle Design Plc | Particle formation methods and their products |
AUPR197000A0 (en) * | 2000-12-08 | 2001-01-11 | Unisearch Limited | Synthesis of small particles |
US8067032B2 (en) | 2000-12-22 | 2011-11-29 | Baxter International Inc. | Method for preparing submicron particles of antineoplastic agents |
US9700866B2 (en) | 2000-12-22 | 2017-07-11 | Baxter International Inc. | Surfactant systems for delivery of organic compounds |
DE10105801B4 (de) | 2001-02-07 | 2004-07-08 | Henkel Kgaa | Wasch- und Reinigungsmittel umfassend feine Mikropartikel mit Reinigungsmittelbestandteilen |
JP2004534900A (ja) | 2001-07-12 | 2004-11-18 | イーストマン コダック カンパニー | 圧縮流体配合物 |
GB0208742D0 (en) | 2002-04-17 | 2002-05-29 | Bradford Particle Design Ltd | Particulate materials |
GB0117696D0 (en) | 2001-07-20 | 2001-09-12 | Bradford Particle Design Plc | Particle information |
EP1429749A2 (fr) | 2001-09-26 | 2004-06-23 | Baxter International Inc. | Preparation de nanoparticules submicroniques par dispersion et elimination d'un solvant ou d'une phase liquide |
US20060003012A9 (en) | 2001-09-26 | 2006-01-05 | Sean Brynjelsen | Preparation of submicron solid particle suspensions by sonication of multiphase systems |
ES2318145T3 (es) * | 2002-02-19 | 2009-05-01 | Resolution Chemicals Limited | Esterilizacion de esteroides por medio de disolventes. |
DE10218107A1 (de) * | 2002-04-23 | 2003-11-20 | Jenapharm Gmbh | Verfahren zum Herstellen von Kristallen von Steroiden, danach erhältliche Kristalle und deren Verwendung in pharmazeutischen Formulierungen |
US9339459B2 (en) | 2003-04-24 | 2016-05-17 | Nektar Therapeutics | Particulate materials |
MY143936A (en) | 2003-03-27 | 2011-07-29 | Nycomed Gmbh | Process for preparing crystalline ciclesonide with defined particle size |
BRPI0409962A (pt) | 2003-05-08 | 2006-04-25 | Nektar Therapeutics Uk Ltd | co-formulação particulada de uma substáncia ativa e um excipiente, composição farmacêutica ou nutricêutrica, produto farmacêutico ou nutricêutico, método para preparar uma co-formulação particulada de uma substáncia ativa e um excipiente, e, uso de uma substáncia ativa e um excipiente |
US20060275219A1 (en) * | 2003-06-10 | 2006-12-07 | Taisho Pharmaceutical Co., Ltd. | Radial spherical crystallization product, process for producing the same, and dry powder preparation containing the crystallization product |
NZ545146A (en) | 2006-02-07 | 2009-03-31 | Ind Res Ltd | Near-critical fluid fractionation process for extracting plant or animal material |
CA2932389A1 (fr) | 2006-03-24 | 2007-10-04 | Auxilium International Holdings, Inc. | Compositions stabilisees contenant des medicaments labiles alcalins |
CA2676803A1 (fr) * | 2007-01-31 | 2008-08-07 | Toyama Chemical Co., Ltd. | Nouveau cristal de piperacilline sodique |
PL2425820T3 (pl) | 2007-02-11 | 2015-08-31 | Map Pharmaceuticals Inc | Sposób terapeutycznego stosowania dhe w celu umożliwienia szybkiego złagodzenia migreny przy jednoczesnym zminimalizowaniu profilu działań niepożądanych |
EP2156823A1 (fr) * | 2008-08-14 | 2010-02-24 | Pharmatex Italia Srl | Processus de préparation de composés pharmaceutiques poudrés stériles sous la forme de micro et nano particules |
US8071656B2 (en) | 2009-03-03 | 2011-12-06 | Dynasep Llc | Nylon extraction from commingled materials |
WO2011015226A1 (fr) * | 2009-08-03 | 2011-02-10 | Pharmatex Italia Srl | Procédé de préparation de composés pharmaceutiques stériles en poudre sous forme de microparticules et nanoparticules |
CA2767773C (fr) | 2011-02-11 | 2015-11-24 | Grain Processing Corporation | Composition comprenant un sel et un agent d'interruption de cristallisation |
CA2897670C (fr) * | 2013-01-07 | 2021-04-06 | Aciex Therapeutics, Inc. | Preparations d'agents therapeutiques hydrophobes, leurs procedes de fabrication et d'utilisation |
US8778181B1 (en) * | 2013-03-14 | 2014-07-15 | Crititech, Inc. | Equipment assembly for and method of processing particles |
WO2022149937A2 (fr) * | 2021-01-08 | 2022-07-14 | 서울대학교 산학협력단 | Agent thérapeutique à base de sécrétome de cellules séchées pour le traitement de l'arthrose |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB899667A (en) * | 1960-04-19 | 1962-06-27 | Glaxo Lab Ltd | Crystalline griseofulvin |
US4044126A (en) * | 1972-04-20 | 1977-08-23 | Allen & Hanburys Limited | Steroidal aerosol compositions and process for the preparation thereof |
MX3864E (es) * | 1975-05-27 | 1981-08-26 | Syntex Corp | Un proceso para prepara el compuesto cristalino 6-fluiro-11b 21-dihiroxi-16 17-isopropilidendioxipregna-1 4-dien-3 20-diona |
FR2608988B1 (fr) * | 1986-12-31 | 1991-01-11 | Centre Nat Rech Scient | Procede de preparation de systemes colloidaux dispersibles d'une substance, sous forme de nanoparticules |
-
1989
- 1989-09-06 WO PCT/US1989/003783 patent/WO1990003782A2/fr active IP Right Grant
- 1989-09-06 DE DE89910390T patent/DE68907062T2/de not_active Expired - Lifetime
- 1989-09-06 AU AU42198/89A patent/AU624421B2/en not_active Expired
- 1989-09-06 HU HU895780A patent/HU209603B/hu unknown
- 1989-09-06 KR KR1019900701214A patent/KR0132576B1/ko not_active IP Right Cessation
- 1989-09-06 JP JP1509713A patent/JP2843857B2/ja not_active Expired - Lifetime
- 1989-09-06 EP EP89910390A patent/EP0437451B1/fr not_active Expired - Lifetime
- 1989-09-29 CA CA000615398A patent/CA1338106C/fr not_active Expired - Fee Related
-
1991
- 1991-04-03 DK DK199100590A patent/DK175208B1/da not_active IP Right Cessation
-
1996
- 1996-05-23 HK HK89396A patent/HK89396A/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
HK89396A (en) | 1996-05-31 |
DK59091D0 (da) | 1991-04-03 |
WO1990003782A2 (fr) | 1990-04-19 |
AU4219889A (en) | 1990-05-01 |
EP0437451B1 (fr) | 1993-06-09 |
WO1990003782A3 (fr) | 1990-07-26 |
DE68907062T2 (de) | 1993-10-07 |
DE68907062D1 (de) | 1993-07-15 |
KR0132576B1 (ko) | 1998-04-17 |
DK59091A (da) | 1991-04-03 |
HU895780D0 (en) | 1991-07-29 |
JPH04500925A (ja) | 1992-02-20 |
EP0437451A1 (fr) | 1991-07-24 |
AU624421B2 (en) | 1992-06-11 |
HU209603B (en) | 1994-09-28 |
KR900701253A (ko) | 1990-12-01 |
JP2843857B2 (ja) | 1999-01-06 |
HUT56265A (en) | 1991-08-28 |
CA1338106C (fr) | 1996-03-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUP | Patent expired |