DK174598B1 - Glycosyleret eller ikke glycosyleret rekombinant polypeptid med aktivitet som human granulocyt/makrofag og eosinofil cellevækstfaktor, fremgangsmåde til fremstilling af polypeptidet, nucleotidsekvens kodende for polypeptidet, ..... - Google Patents

Glycosyleret eller ikke glycosyleret rekombinant polypeptid med aktivitet som human granulocyt/makrofag og eosinofil cellevækstfaktor, fremgangsmåde til fremstilling af polypeptidet, nucleotidsekvens kodende for polypeptidet, ..... Download PDF

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Publication number
DK174598B1
DK174598B1 DK198603452A DK345286A DK174598B1 DK 174598 B1 DK174598 B1 DK 174598B1 DK 198603452 A DK198603452 A DK 198603452A DK 345286 A DK345286 A DK 345286A DK 174598 B1 DK174598 B1 DK 174598B1
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glu
thr
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pro
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DK198603452A
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DK345286A (da
DK345286D0 (da
Inventor
Frank Don Lee
Donna Maye Rennick
Ken-Ichi Arai
Takashi Yokota
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Schering Biotech Corp
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/53—Colony-stimulating factor [CSF]
    • C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Steroid Compounds (AREA)
  • Fats And Perfumes (AREA)
  • Saccharide Compounds (AREA)
DK198603452A 1984-11-20 1986-07-21 Glycosyleret eller ikke glycosyleret rekombinant polypeptid med aktivitet som human granulocyt/makrofag og eosinofil cellevækstfaktor, fremgangsmåde til fremstilling af polypeptidet, nucleotidsekvens kodende for polypeptidet, ..... DK174598B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US67389884A 1984-11-20 1984-11-20
US67389884 1984-11-20
PCT/US1985/002250 WO1986003225A1 (en) 1984-11-20 1985-11-18 cDNA CLONES CODING FOR POLYPEPTIDES EXHIBITING HUMAN GRANULOCYTE MACROPHAGE AND EOSINOPHIL CELLULAR GROWTH FACTOR ACTIVITY
US8502250 1985-11-18

Publications (3)

Publication Number Publication Date
DK345286A DK345286A (da) 1986-07-21
DK345286D0 DK345286D0 (da) 1986-07-21
DK174598B1 true DK174598B1 (da) 2003-07-14

Family

ID=24704538

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198603452A DK174598B1 (da) 1984-11-20 1986-07-21 Glycosyleret eller ikke glycosyleret rekombinant polypeptid med aktivitet som human granulocyt/makrofag og eosinofil cellevækstfaktor, fremgangsmåde til fremstilling af polypeptidet, nucleotidsekvens kodende for polypeptidet, .....

Country Status (26)

Country Link
EP (1) EP0202300B1 (pt)
JP (1) JP3038348B2 (pt)
KR (1) KR920003822B1 (pt)
CN (3) CN1031465C (pt)
AT (1) ATE82321T1 (pt)
AU (1) AU608741B2 (pt)
BG (1) BG60840B2 (pt)
DE (1) DE3586826T2 (pt)
DK (1) DK174598B1 (pt)
ES (1) ES8705470A1 (pt)
FI (1) FI103986B1 (pt)
GR (1) GR852786B (pt)
HK (1) HK6096A (pt)
HU (1) HU213226B (pt)
IE (1) IE59581B1 (pt)
IL (1) IL77080A (pt)
LU (1) LU88360I2 (pt)
MX (1) MX9203397A (pt)
MY (1) MY101971A (pt)
NL (1) NL930120I2 (pt)
NO (1) NO862903L (pt)
NZ (1) NZ214225A (pt)
OA (1) OA08671A (pt)
PT (1) PT81513B (pt)
WO (1) WO1986003225A1 (pt)
ZA (1) ZA858833B (pt)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU594014B2 (en) * 1984-03-21 1990-03-01 Research Corporation Technologies, Inc. Recombinant DNA molecules
UA29377C2 (uk) * 1984-09-19 2000-11-15 Новартіс Аг Спосіб отримання білка з активністю колонієстимулювального фактора гранулоцитів та макрофагів(gm-csf) приматів
AU588819B2 (en) * 1984-10-29 1989-09-28 Immunex Corporation Cloning of human granulocyte-macrophage colony stimulating factor gene
ZA856108B (en) * 1984-10-29 1986-10-29 Immunex Corp Cloning of human granulocyte-macrophage colony simulating factor gene
US5078996A (en) * 1985-08-16 1992-01-07 Immunex Corporation Activation of macrophage tumoricidal activity by granulocyte-macrophage colony stimulating factor
WO1987002060A1 (en) * 1985-10-03 1987-04-09 Biogen N.V. Human granulocyte-macrophage colony stimulating factor-like polypeptides and processes for producing them in high yields in microbial cells
JPH0618778B2 (ja) * 1985-10-04 1994-03-16 中外製薬株式会社 白血球減少症治療剤
DE3545568A1 (de) * 1985-12-21 1987-07-16 Hoechst Ag Gm-csf-protein, seine derivate, herstellung solcher proteine und ihre verwendung
US5298603A (en) * 1985-12-21 1994-03-29 Hoechst Aktiengesellschaft GM-CSF protein, its derivatives, the preparation of proteins of this type, and their use
JP2583770B2 (ja) * 1986-09-17 1997-02-19 大塚製薬株式会社 遺伝子
EP0276846A3 (en) * 1987-01-29 1989-07-26 Zymogenetics, Inc. Colony-stimulating factor derivatives
JPS6420097A (en) * 1987-03-02 1989-01-24 Sumitomo Chemical Co Human granulocyte-macrophage colony stimulating factor
AU621051B2 (en) * 1987-04-28 1992-03-05 Amgen, Inc. Method for purifying granulocyte-macrophage colony stimulating factor
AU626530B2 (en) * 1987-07-17 1992-08-06 Schering Biotech Corporation Human granulocyte-macrophage colony stimulating factor and muteins thereof
ZA885101B (en) * 1987-07-17 1989-03-29 Schering Biotech Corp Human granulocyte macrophage colony stimulating factor and muteins thereof
GB2212159B (en) * 1987-11-13 1992-01-22 British Bio Technology Synthetic gene for human granulocyte/macrophage colony stimulating factor.
EP0413721A4 (en) * 1988-04-21 1991-11-13 Medvet Science Pty. Ltd. Human gm-csf variants
US5109119A (en) * 1989-06-06 1992-04-28 Schering Corporation Crystalline r-h-gm-csf and method
KR100448021B1 (ko) * 2001-12-28 2004-09-08 크레아젠 주식회사 마우스 과립구 대식세포 콜로니 촉진인자 발현벡터 ｐＧＭ-ＣＳＦ로 형질전환된 대장균 및 상기 마우스 과립구 대식세포 콜로니 촉진인자의 대량생산방법
JP2006517914A (ja) * 2002-09-20 2006-08-03 デンドレオン コーポレイション 中ないし高分化型がんの免疫療法用組成物および治療方法。

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4438032A (en) * 1981-01-30 1984-03-20 The Regents Of The University Of California Unique T-lymphocyte line and products derived therefrom
AU594014B2 (en) * 1984-03-21 1990-03-01 Research Corporation Technologies, Inc. Recombinant DNA molecules
EP0188479B1 (en) * 1984-07-06 1991-09-11 Sandoz Ag Lymphokine production and purification
ZA856108B (en) * 1984-10-29 1986-10-29 Immunex Corp Cloning of human granulocyte-macrophage colony simulating factor gene
AU588819B2 (en) * 1984-10-29 1989-09-28 Immunex Corporation Cloning of human granulocyte-macrophage colony stimulating factor gene

Also Published As

Publication number Publication date
MY101971A (en) 1992-02-29
PT81513A (en) 1985-12-01
LU88360I2 (fr) 1994-05-04
ES548998A0 (es) 1987-05-01
CN1086543A (zh) 1994-05-11
FI103986B (fi) 1999-10-29
NZ214225A (en) 1991-05-28
CN1020473C (zh) 1993-05-05
NL930120I2 (nl) 1994-07-01
HU213226B (en) 1997-03-28
AU608741B2 (en) 1991-04-18
DE3586826D1 (de) 1992-12-17
HUT40464A (en) 1986-12-28
FI103986B1 (fi) 1999-10-29
ES8705470A1 (es) 1987-05-01
ATE82321T1 (de) 1992-11-15
DK345286A (da) 1986-07-21
IL77080A (en) 1998-02-08
FI862674A0 (fi) 1986-06-24
IE59581B1 (en) 1994-03-09
JP3038348B2 (ja) 2000-05-08
KR920003822B1 (ko) 1992-05-15
MX9203397A (es) 1992-07-01
CN1031465C (zh) 1996-04-03
EP0202300A1 (en) 1986-11-26
FI862674A (fi) 1986-06-24
BG60840B2 (bg) 1996-04-30
IL77080A0 (en) 1986-04-29
PT81513B (pt) 1988-03-03
HK6096A (en) 1996-01-19
KR860700359A (ko) 1986-10-06
DE3586826T2 (de) 1993-03-25
WO1986003225A1 (en) 1986-06-05
NL930120I1 (nl) 1993-11-01
NO862903L (no) 1986-09-18
AU5196386A (en) 1986-06-18
JPS62501259A (ja) 1987-05-21
EP0202300B1 (en) 1992-11-11
NO862903D0 (no) 1986-07-18
DK345286D0 (da) 1986-07-21
CN85109132A (zh) 1986-12-03
IE852889L (en) 1986-05-20
OA08671A (en) 1989-03-31
GR852786B (pt) 1986-03-20
CN1045539C (zh) 1999-10-13
ZA858833B (en) 1986-06-25

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