DK173629B1 - Ændret pneumolysin, vaccine indeholdende det ændrede pneumolysin, rekombinant plasmid, som koder for det ændrede pneumolysin, hybrid værtscelle indeholdende det rekombinante plasmid, metoder til fremstilling af det ændrede........ - Google Patents
Ændret pneumolysin, vaccine indeholdende det ændrede pneumolysin, rekombinant plasmid, som koder for det ændrede pneumolysin, hybrid værtscelle indeholdende det rekombinante plasmid, metoder til fremstilling af det ændrede........ Download PDFInfo
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- DK173629B1 DK173629B1 DK199101155A DK115591A DK173629B1 DK 173629 B1 DK173629 B1 DK 173629B1 DK 199101155 A DK199101155 A DK 199101155A DK 115591 A DK115591 A DK 115591A DK 173629 B1 DK173629 B1 DK 173629B1
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- 101710183389 Pneumolysin Proteins 0.000 title claims abstract description 90
- 229960005486 vaccine Drugs 0.000 title claims abstract description 33
- 239000013612 plasmid Substances 0.000 title claims description 13
- 238000000034 method Methods 0.000 title claims description 11
- 229920001282 polysaccharide Polymers 0.000 claims abstract description 29
- 239000005017 polysaccharide Substances 0.000 claims abstract description 29
- 150000004676 glycans Chemical class 0.000 claims abstract description 28
- 108090000623 proteins and genes Proteins 0.000 claims description 21
- 239000000463 material Substances 0.000 claims description 15
- 239000002775 capsule Substances 0.000 claims description 14
- 102000004169 proteins and genes Human genes 0.000 claims description 14
- 108091028043 Nucleic acid sequence Proteins 0.000 claims description 9
- 108020004414 DNA Proteins 0.000 claims description 6
- 241000193998 Streptococcus pneumoniae Species 0.000 claims description 6
- 229940031000 streptococcus pneumoniae Drugs 0.000 claims description 6
- 108091081024 Start codon Proteins 0.000 claims description 5
- 238000004519 manufacturing process Methods 0.000 claims description 4
- 238000013518 transcription Methods 0.000 claims description 3
- 230000035897 transcription Effects 0.000 claims description 3
- 230000001939 inductive effect Effects 0.000 claims description 2
- 238000013519 translation Methods 0.000 claims description 2
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- 241000880493 Leptailurus serval Species 0.000 claims 6
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
- C07K14/3156—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Rheumatology (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Pain & Pain Management (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Exchange Systems With Centralized Control (AREA)
- Manufacturing Of Steel Electrode Plates (AREA)
- Current-Collector Devices For Electrically Propelled Vehicles (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AUPJ198988 | 1988-12-16 | ||
| AUPJ198988 | 1988-12-16 | ||
| PCT/AU1989/000539 WO1990006951A1 (en) | 1988-12-16 | 1989-12-15 | Pneumolysin mutants and pneumococcal vaccines made therefrom |
| AU8900539 | 1989-12-15 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK115591D0 DK115591D0 (da) | 1991-06-14 |
| DK115591A DK115591A (da) | 1991-08-14 |
| DK173629B1 true DK173629B1 (da) | 2001-05-14 |
Family
ID=3773589
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK199101155A DK173629B1 (da) | 1988-12-16 | 1991-06-14 | Ændret pneumolysin, vaccine indeholdende det ændrede pneumolysin, rekombinant plasmid, som koder for det ændrede pneumolysin, hybrid værtscelle indeholdende det rekombinante plasmid, metoder til fremstilling af det ændrede........ |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP0449856B1 (fi) |
| JP (1) | JP3237842B2 (fi) |
| AT (1) | ATE205534T1 (fi) |
| AU (1) | AU626961B2 (fi) |
| BG (1) | BG51358A3 (fi) |
| CA (1) | CA2005704C (fi) |
| DE (1) | DE68929323T2 (fi) |
| DK (1) | DK173629B1 (fi) |
| ES (1) | ES2160570T3 (fi) |
| FI (1) | FI103122B (fi) |
| HU (1) | HUT58804A (fi) |
| MC (1) | MC2178A1 (fi) |
| NO (1) | NO304317B1 (fi) |
| RU (1) | RU2121481C1 (fi) |
| WO (1) | WO1990006951A1 (fi) |
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| WO1995016711A1 (es) * | 1993-12-17 | 1995-06-22 | Universidad De Oviedo | Anticuerpos contra la neumolisina y sus aplicaciones |
| US8791237B2 (en) | 1994-11-08 | 2014-07-29 | The Trustees Of The University Of Pennsylvania | Compositions and methods for treatment of non-hodgkins lymphoma |
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| EA021391B1 (ru) | 2007-03-02 | 2015-06-30 | Глаксосмитклайн Байолоджикалс С.А. | Способ индукции иммунного ответа, вакцинная композиция, ее применение и набор |
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| US11207396B2 (en) | 2013-05-17 | 2021-12-28 | The Board Of Regents Of The University Of Texas System | Immunization to protect against adverse cardiac events relating to pneumococcal infection |
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| KR102411781B1 (ko) | 2013-12-31 | 2022-06-22 | 인펙셔스 디지즈 리서치 인스티튜트 (아이디알아이) | 단일 바이알 백신 제형 |
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-
1989
- 1989-12-15 AT AT90900035T patent/ATE205534T1/de not_active IP Right Cessation
- 1989-12-15 DE DE68929323T patent/DE68929323T2/de not_active Expired - Lifetime
- 1989-12-15 AU AU47564/90A patent/AU626961B2/en not_active Expired
- 1989-12-15 WO PCT/AU1989/000539 patent/WO1990006951A1/en active IP Right Grant
- 1989-12-15 CA CA002005704A patent/CA2005704C/en not_active Expired - Lifetime
- 1989-12-15 MC MC89@@D patent/MC2178A1/xx unknown
- 1989-12-15 ES ES90900035T patent/ES2160570T3/es not_active Expired - Lifetime
- 1989-12-15 JP JP50093590A patent/JP3237842B2/ja not_active Expired - Lifetime
- 1989-12-15 EP EP90900035A patent/EP0449856B1/en not_active Expired - Lifetime
- 1989-12-15 HU HU90433A patent/HUT58804A/hu unknown
- 1989-12-15 RU SU4895772A patent/RU2121481C1/ru active
-
1991
- 1991-06-11 NO NO912226A patent/NO304317B1/no not_active IP Right Cessation
- 1991-06-12 BG BG094614A patent/BG51358A3/xx unknown
- 1991-06-14 FI FI912878A patent/FI103122B/fi active
- 1991-06-14 DK DK199101155A patent/DK173629B1/da not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| NO912226L (no) | 1991-07-25 |
| ES2160570T3 (es) | 2001-11-16 |
| JP3237842B2 (ja) | 2001-12-10 |
| CA2005704C (en) | 2003-02-11 |
| EP0449856A1 (en) | 1991-10-09 |
| WO1990006951A1 (en) | 1990-06-28 |
| NO912226D0 (no) | 1991-06-11 |
| JPH04503948A (ja) | 1992-07-16 |
| CA2005704A1 (en) | 1990-06-16 |
| AU4756490A (en) | 1990-07-10 |
| FI912878A0 (fi) | 1991-06-14 |
| DE68929323D1 (de) | 2001-10-18 |
| MC2178A1 (fr) | 1992-05-22 |
| FI103122B1 (fi) | 1999-04-30 |
| ATE205534T1 (de) | 2001-09-15 |
| DE68929323T2 (de) | 2002-04-18 |
| DK115591D0 (da) | 1991-06-14 |
| NO304317B1 (no) | 1998-11-30 |
| BG51358A3 (en) | 1993-04-15 |
| FI103122B (fi) | 1999-04-30 |
| RU2121481C1 (ru) | 1998-11-10 |
| EP0449856A4 (en) | 1992-05-20 |
| HUT58804A (en) | 1992-03-30 |
| DK115591A (da) | 1991-08-14 |
| AU626961B2 (en) | 1992-08-13 |
| EP0449856B1 (en) | 2001-09-12 |
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Legal Events
| Date | Code | Title | Description |
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| B1 | Patent granted (law 1993) | ||
| PUP | Patent expired |