DK173007B1 - Fremgangsmåde til semisyntetisk fremstilling af humaninsulin og modificeret humaninsulin til brug ved fremgangsmåden - Google Patents

Fremgangsmåde til semisyntetisk fremstilling af humaninsulin og modificeret humaninsulin til brug ved fremgangsmåden Download PDF

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Publication number
DK173007B1
DK173007B1 DK198301616A DK161683A DK173007B1 DK 173007 B1 DK173007 B1 DK 173007B1 DK 198301616 A DK198301616 A DK 198301616A DK 161683 A DK161683 A DK 161683A DK 173007 B1 DK173007 B1 DK 173007B1
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DK
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Prior art keywords
phe
insulin
human insulin
des
semi
Prior art date
Application number
DK198301616A
Other languages
Danish (da)
English (en)
Other versions
DK161683A (da
DK161683D0 (da
Inventor
Francois Egbert Ab Houdenhoven
Gijsbert Willem Karel Va Dedem
Original Assignee
Akzo Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nv filed Critical Akzo Nv
Publication of DK161683D0 publication Critical patent/DK161683D0/da
Publication of DK161683A publication Critical patent/DK161683A/da
Application granted granted Critical
Publication of DK173007B1 publication Critical patent/DK173007B1/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/26—Containing cys-cys disulfide bridge between nonadjacent cysteine residues

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK198301616A 1982-04-21 1983-04-13 Fremgangsmåde til semisyntetisk fremstilling af humaninsulin og modificeret humaninsulin til brug ved fremgangsmåden DK173007B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL8201650 1982-04-21
NL8201650A NL8201650A (nl) 1982-04-21 1982-04-21 Semisynthetische bereiding van humane insuline.

Publications (3)

Publication Number Publication Date
DK161683D0 DK161683D0 (da) 1983-04-13
DK161683A DK161683A (da) 1983-10-22
DK173007B1 true DK173007B1 (da) 1999-11-08

Family

ID=19839621

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198301616A DK173007B1 (da) 1982-04-21 1983-04-13 Fremgangsmåde til semisyntetisk fremstilling af humaninsulin og modificeret humaninsulin til brug ved fremgangsmåden

Country Status (15)

Country Link
US (1) US4840897A (ru)
EP (1) EP0092280B1 (ru)
JP (2) JPS58189149A (ru)
AT (1) ATE42203T1 (ru)
AU (1) AU554050B2 (ru)
CA (1) CA1202587A (ru)
DE (1) DE3379640D1 (ru)
DK (1) DK173007B1 (ru)
ES (1) ES8405760A1 (ru)
HU (1) HU189268B (ru)
IL (1) IL68397A (ru)
NL (1) NL8201650A (ru)
PL (1) PL143571B1 (ru)
SU (1) SU1232148A3 (ru)
ZA (1) ZA832602B (ru)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3326472A1 (de) * 1983-07-22 1985-02-14 Hoechst Ag, 6230 Frankfurt Neue insulin-derivate, verfahren zu deren herstellung und deren verwendung sowie pharmazeutische mittel zur behandlung des diabetes mellitus
DE3326473A1 (de) * 1983-07-22 1985-01-31 Hoechst Ag, 6230 Frankfurt Pharmazeutisches mittel zur behandlung des diabetes mellitus
DE3327709A1 (de) * 1983-07-29 1985-02-07 Hoechst Ag, 6230 Frankfurt Insulin-derivat-kristallsuspensionen, verfahren zu deren herstellung und deren verwendung
DE3333640A1 (de) * 1983-09-17 1985-04-25 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von insulin-derivaten, deren b-kette c-terminal verlaengert ist, neue basisch modifizierte insulin-derivate diese enthaltende mittel und ihre verwendung
DK309184D0 (da) * 1984-06-25 1984-06-25 Nordisk Insulinlab Fremgangsmaade til isolering af insulin eller insulinlignende materiale fra en fermenteringsvaeske
CN113956326B (zh) * 2021-09-15 2024-05-28 河南工业大学 一种短肽单体，结构自愈型肽基水凝胶及其应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3276961A (en) * 1963-04-08 1966-10-04 Squibb & Sons Inc Process for preparing human insulin
US4182654A (en) * 1974-09-18 1980-01-08 Pierce Chemical Company Production of polypeptides using polynucleotides
JPS55138393A (en) * 1979-04-13 1980-10-29 Shionogi & Co Ltd Semisynthesis of insulin
JPS55138391A (en) * 1979-04-13 1980-10-29 Shionogi & Co Ltd New synthetic method of peptide derivative
DE3064479D1 (en) * 1979-04-13 1983-09-08 Shionogi & Co Process for preparing a b30-threonine insulin
US4343898A (en) * 1980-02-11 1982-08-10 Novo Industri A/S Process for preparing esters of human insulin
DK147437A (en) * 1980-02-11 1900-01-01 Process for preparing human insulin or threonine B30 esters of human insulin, or a salt or complex thereof
DK319780A (da) * 1980-07-24 1982-01-25 Forenede Bryggerier As Fremgangsmaade til enzymatisk udskiftning af b-30 aminosyren i insuliner
DE3327928A1 (de) * 1983-08-03 1985-02-21 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von insulin-derivaten

Also Published As

Publication number Publication date
HU189268B (en) 1986-06-30
AU554050B2 (en) 1986-08-07
CA1202587A (en) 1986-04-01
JPH0533993B2 (ru) 1993-05-20
PL241575A1 (en) 1983-12-19
AU1355483A (en) 1983-10-27
JPS58189149A (ja) 1983-11-04
ATE42203T1 (de) 1989-05-15
ES521674A0 (es) 1984-06-16
EP0092280B1 (en) 1989-04-19
IL68397A0 (en) 1983-07-31
NL8201650A (nl) 1983-11-16
ZA832602B (en) 1984-01-25
ES8405760A1 (es) 1984-06-16
DK161683A (da) 1983-10-22
PL143571B1 (en) 1988-02-29
IL68397A (en) 1986-01-31
JPH05339290A (ja) 1993-12-21
US4840897A (en) 1989-06-20
SU1232148A3 (ru) 1986-05-15
JPH0735399B2 (ja) 1995-04-19
EP0092280A1 (en) 1983-10-26
DK161683D0 (da) 1983-04-13
DE3379640D1 (en) 1989-05-24

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PBP Patent lapsed
B1 Patent granted (law 1993)
PUP Patent expired