ZA832602B - Semi-synthetic preparation of human insulin - Google Patents

Semi-synthetic preparation of human insulin

Info

Publication number
ZA832602B
ZA832602B ZA832602A ZA832602A ZA832602B ZA 832602 B ZA832602 B ZA 832602B ZA 832602 A ZA832602 A ZA 832602A ZA 832602 A ZA832602 A ZA 832602A ZA 832602 B ZA832602 B ZA 832602B
Authority
ZA
South Africa
Prior art keywords
human insulin
semi
ester
synthetic preparation
sugar residue
Prior art date
Application number
ZA832602A
Other languages
English (en)
Inventor
Gijsbert Willem Karel Va Dedem
Francois Egbert Ab Houdenhoven
Original Assignee
Akzo Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nv filed Critical Akzo Nv
Publication of ZA832602B publication Critical patent/ZA832602B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/26—Containing cys-cys disulfide bridge between nonadjacent cysteine residues

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
ZA832602A 1982-04-21 1983-04-13 Semi-synthetic preparation of human insulin ZA832602B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL8201650A NL8201650A (nl) 1982-04-21 1982-04-21 Semisynthetische bereiding van humane insuline.

Publications (1)

Publication Number Publication Date
ZA832602B true ZA832602B (en) 1984-01-25

Family

ID=19839621

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA832602A ZA832602B (en) 1982-04-21 1983-04-13 Semi-synthetic preparation of human insulin

Country Status (15)

Country Link
US (1) US4840897A (ru)
EP (1) EP0092280B1 (ru)
JP (2) JPS58189149A (ru)
AT (1) ATE42203T1 (ru)
AU (1) AU554050B2 (ru)
CA (1) CA1202587A (ru)
DE (1) DE3379640D1 (ru)
DK (1) DK173007B1 (ru)
ES (1) ES8405760A1 (ru)
HU (1) HU189268B (ru)
IL (1) IL68397A (ru)
NL (1) NL8201650A (ru)
PL (1) PL143571B1 (ru)
SU (1) SU1232148A3 (ru)
ZA (1) ZA832602B (ru)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3326472A1 (de) * 1983-07-22 1985-02-14 Hoechst Ag, 6230 Frankfurt Neue insulin-derivate, verfahren zu deren herstellung und deren verwendung sowie pharmazeutische mittel zur behandlung des diabetes mellitus
DE3326473A1 (de) * 1983-07-22 1985-01-31 Hoechst Ag, 6230 Frankfurt Pharmazeutisches mittel zur behandlung des diabetes mellitus
DE3327709A1 (de) * 1983-07-29 1985-02-07 Hoechst Ag, 6230 Frankfurt Insulin-derivat-kristallsuspensionen, verfahren zu deren herstellung und deren verwendung
DE3333640A1 (de) * 1983-09-17 1985-04-25 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von insulin-derivaten, deren b-kette c-terminal verlaengert ist, neue basisch modifizierte insulin-derivate diese enthaltende mittel und ihre verwendung
DK309184D0 (da) * 1984-06-25 1984-06-25 Nordisk Insulinlab Fremgangsmaade til isolering af insulin eller insulinlignende materiale fra en fermenteringsvaeske
CN113956326B (zh) * 2021-09-15 2024-05-28 河南工业大学 一种短肽单体，结构自愈型肽基水凝胶及其应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3276961A (en) * 1963-04-08 1966-10-04 Squibb & Sons Inc Process for preparing human insulin
US4182654A (en) * 1974-09-18 1980-01-08 Pierce Chemical Company Production of polypeptides using polynucleotides
JPS55138393A (en) * 1979-04-13 1980-10-29 Shionogi & Co Ltd Semisynthesis of insulin
JPS55138391A (en) * 1979-04-13 1980-10-29 Shionogi & Co Ltd New synthetic method of peptide derivative
DE3064479D1 (en) * 1979-04-13 1983-09-08 Shionogi & Co Process for preparing a b30-threonine insulin
US4343898A (en) * 1980-02-11 1982-08-10 Novo Industri A/S Process for preparing esters of human insulin
DK147437A (en) * 1980-02-11 1900-01-01 Process for preparing human insulin or threonine B30 esters of human insulin, or a salt or complex thereof
DK319780A (da) * 1980-07-24 1982-01-25 Forenede Bryggerier As Fremgangsmaade til enzymatisk udskiftning af b-30 aminosyren i insuliner
DE3327928A1 (de) * 1983-08-03 1985-02-21 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von insulin-derivaten

Also Published As

Publication number Publication date
HU189268B (en) 1986-06-30
AU554050B2 (en) 1986-08-07
CA1202587A (en) 1986-04-01
JPH0533993B2 (ru) 1993-05-20
PL241575A1 (en) 1983-12-19
AU1355483A (en) 1983-10-27
JPS58189149A (ja) 1983-11-04
ATE42203T1 (de) 1989-05-15
ES521674A0 (es) 1984-06-16
EP0092280B1 (en) 1989-04-19
IL68397A0 (en) 1983-07-31
NL8201650A (nl) 1983-11-16
ES8405760A1 (es) 1984-06-16
DK161683A (da) 1983-10-22
PL143571B1 (en) 1988-02-29
IL68397A (en) 1986-01-31
JPH05339290A (ja) 1993-12-21
US4840897A (en) 1989-06-20
SU1232148A3 (ru) 1986-05-15
JPH0735399B2 (ja) 1995-04-19
EP0092280A1 (en) 1983-10-26
DK161683D0 (da) 1983-04-13
DK173007B1 (da) 1999-11-08
DE3379640D1 (en) 1989-05-24

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