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Toa Eiyo Ltd
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Toa Eiyo Ltd
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Priority to JP22949087ApriorityCriticalpatent/JPS6474994A/en
Publication of JPS6474994ApublicationCriticalpatent/JPS6474994A/en
Preparation Of Compounds By Using Micro-Organisms
(AREA)
Abstract
PURPOSE:To obtain the titled compound to be converted to coreylactone in high yield and in high optical purity, an intermediate for prostaglandin derivative, by selectively hydrolyzing a cyclopentenyl acetate derivative with an enzyme. CONSTITUTION:A cyclopentenyl acetate [e.g. (+ or -)-cis-4-tertiary butoxy-2- cyclopentenyl acetate] shown by formula I (R is alkyl or aryl) is selectively hydrolyzed with an enzyme (preferable lipase or baker's yeast] to give the aimed compound [e.g. (+)-(1S,4R)-4-tertiary butoxy-2-cyclopentenol] shown by formula II.
JP22949087A1987-09-161987-09-16Production of optically active cyclopentenol derivative
PendingJPS6474994A
(en)