DK1729824T3 - Phospholipidanaloger til behandling af cancere - Google Patents
Phospholipidanaloger til behandling af cancereInfo
- Publication number
- DK1729824T3 DK1729824T3 DK05729873T DK05729873T DK1729824T3 DK 1729824 T3 DK1729824 T3 DK 1729824T3 DK 05729873 T DK05729873 T DK 05729873T DK 05729873 T DK05729873 T DK 05729873T DK 1729824 T3 DK1729824 T3 DK 1729824T3
- Authority
- DK
- Denmark
- Prior art keywords
- cancers
- treatment
- phospholipid analogues
- phospholipid
- analogues
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 2
- 150000003904 phospholipids Chemical class 0.000 title 1
- 239000000032 diagnostic agent Substances 0.000 abstract 1
- 229940039227 diagnostic agent Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- -1 phospholipid ether analogs Chemical class 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0489—Phosphates or phosphonates, e.g. bone-seeking phosphonates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0404—Lipids, e.g. triglycerides; Polycationic carriers
- A61K51/0408—Phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
- G01N33/57492—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic Table
- C07F13/005—Compounds without a metal-carbon linkage
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Cell Biology (AREA)
- Biophysics (AREA)
- Optics & Photonics (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- Analytical Chemistry (AREA)
- Urology & Nephrology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Food Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Hospice & Palliative Care (AREA)
- General Engineering & Computer Science (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US52116604P | 2004-03-02 | 2004-03-02 | |
| PCT/US2005/006681 WO2005084716A2 (en) | 2004-03-02 | 2005-03-02 | Phospholipid analogs for diagnosis and treatment of cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1729824T3 true DK1729824T3 (da) | 2009-11-02 |
Family
ID=34919310
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK05729873T DK1729824T3 (da) | 2004-03-02 | 2005-03-02 | Phospholipidanaloger til behandling af cancere |
Country Status (17)
| Country | Link |
|---|---|
| US (3) | US8535641B2 (xx) |
| EP (3) | EP2044961B1 (xx) |
| JP (7) | JP2007528374A (xx) |
| KR (1) | KR20070015518A (xx) |
| CN (1) | CN1929869B (xx) |
| AT (1) | ATE437657T1 (xx) |
| AU (1) | AU2005219412A1 (xx) |
| BR (1) | BRPI0508425A (xx) |
| CA (1) | CA2557698A1 (xx) |
| DE (1) | DE602005015687D1 (xx) |
| DK (1) | DK1729824T3 (xx) |
| ES (3) | ES2440257T3 (xx) |
| HK (1) | HK1130186A1 (xx) |
| IL (1) | IL177645A0 (xx) |
| MX (1) | MXPA06009681A (xx) |
| WO (1) | WO2005084716A2 (xx) |
| ZA (1) | ZA200607042B (xx) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8540968B2 (en) | 2004-03-02 | 2013-09-24 | Cellectar, Inc. | Phospholipid ether analogs as agents for detecting and locating cancer, and methods thereof |
| MXPA06009681A (es) | 2004-03-02 | 2007-03-15 | Cellectar Llc | Analogos de fosfolipido para el diagnostico y tratamiento del cancer. |
| CA2572398A1 (en) * | 2004-07-08 | 2006-02-09 | Cellectar, Llc | Virtual colonoscopy with radiolabeled phospholipid ether analogs |
| KR20080005178A (ko) * | 2004-12-20 | 2008-01-10 | 셀렉타, 엘엘씨 | 암 검출 및 치료용 인지질 에테르 동족체 |
| US20080075660A1 (en) * | 2006-08-15 | 2008-03-27 | Cellectar, Llc | Near infrared-fluorescence using phospholipid ether analog dyes in endoscopic applications |
| US7893286B2 (en) | 2007-06-01 | 2011-02-22 | Cellectar, Inc. | Method for the synthesis of phospholipid ethers |
| US8022235B2 (en) | 2007-06-01 | 2011-09-20 | Cellectar, Inc. | Compositions of phospholipid ether boronic acids and esters and methods for their synthesis and use |
| WO2010011844A1 (en) * | 2008-07-25 | 2010-01-28 | Tufts Medical Center | A system and method of clinical treatment planning of complex, monte carlo-based brachytherapy dose distributions |
| US8871181B2 (en) | 2009-05-11 | 2014-10-28 | Cellectar, Inc. | Fluorescent phospholipid ether compounds, compositions, and methods of use |
| EP2429591B1 (en) | 2009-05-11 | 2015-08-26 | Cellectar, Inc. | Fluorescent phospholipid ether compounds, compositions, and methods of use |
| US7811548B1 (en) | 2009-05-11 | 2010-10-12 | Cellectar, Inc. | Fluorescent phospholipid ether compounds and compositions |
| WO2010144788A2 (en) * | 2009-06-12 | 2010-12-16 | Cellectar, Inc. | Ether and alkyl phospholipid compounds for treating cancer and imaging and detection of cancer stem cells |
| US10007961B2 (en) * | 2009-09-09 | 2018-06-26 | Wisconsin Alumni Research Foundation | Treatment planning system for radiopharmaceuticals |
| JP2013504590A (ja) * | 2009-09-11 | 2013-02-07 | セレクター，インコーポレイティド | 非放射性リン脂質化合物、組成物、及び使用方法 |
| DK3750545T3 (da) | 2014-11-17 | 2024-04-22 | Cellectar Biosciences Inc | Phospholipidetheranaloger som cancermålrettede lægemiddelbærere |
| AU2016349577B2 (en) * | 2015-11-06 | 2023-10-26 | Wisconsin Alumni Research Foundation | Long-lived gadolinium based tumor targeted imaging and therapy agents |
| EP3469367B1 (en) * | 2016-06-14 | 2023-08-02 | Cellectar Biosciences, Inc. | Phospholipid ether analogs for the identification and isolation of circulating tumor cells |
| US11147823B2 (en) * | 2016-07-13 | 2021-10-19 | Wisconsin Alumni Research Foundation | Phospholipid ether analogs for imaging and targeted treatment of pediatric solid tumors |
| US11633506B2 (en) * | 2016-07-18 | 2023-04-25 | Wisconsin Alumni Research Foundation | Using targeted radiotherapy (TRT) to drive anti-tumor immune response to immunotherapies |
| AU2017300361A1 (en) * | 2016-07-18 | 2019-02-07 | Wisconsin Alumni Research Foundation | Radiohalogenated agents for In Situ Immune Modulated Cancer Vaccination |
| US10751430B2 (en) * | 2016-07-25 | 2020-08-25 | Wisconsin Alumni Research Foundation | Targeted radiotherapy chelates for in situ immune modulated cancer vaccination |
| JP7127014B2 (ja) * | 2016-07-25 | 2022-08-29 | ウイスコンシン アラムナイ リサーチ ファウンデーシヨン | 癌のイメージングおよび治療のための放射性リン脂質金属キレート |
| CA3051481A1 (en) | 2017-02-07 | 2018-08-16 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Phospholipid ether (ple) car t cell tumor targeting (ctct) agents |
| WO2018160622A1 (en) | 2017-02-28 | 2018-09-07 | Endocyte, Inc. | Compositions and methods for car t cell therapy |
| JP2021502368A (ja) * | 2017-11-10 | 2021-01-28 | ウイスコンシン アラムナイ リサーチ ファウンデーシヨンＷｉｓｃｏｎｓｉｎ Ａｌｕｍｎｉ Ｒｅｓｅａｒｃｈ Ｆｏｕｎｄａｔｉｏｎ | 免疫療法に対する抗腫瘍免疫応答を促進するための標的化放射線療法（ｔｒｔ）の使用 |
| US20190184040A1 (en) * | 2017-12-15 | 2019-06-20 | Wisconsin Alumni Research Foundation | Targeted Macrocyclic Agents for Dual Modality PET and MRI Imaging of Cancer |
| CN112055595A (zh) | 2018-01-22 | 2020-12-08 | 恩多塞特公司 | Car t细胞的使用方法 |
| US20200354477A1 (en) * | 2018-02-06 | 2020-11-12 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Fluorescein-specific cars exhibiting optimal t cell function against fl-ple labelled tumors |
| KR20220080139A (ko) * | 2019-10-10 | 2022-06-14 | 셀렉타 바이오사이언시스, 인코퍼레이티드 | 인지질-플라바글린 접합체 및 표적화된 암 치료를 위해 이를 사용하는 방법 |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5851526A (en) * | 1985-04-19 | 1998-12-22 | Ludwig Institute For Cancer Research | Methods of treating colon cancer utilizing tumor-specific antibodies |
| US4873075A (en) * | 1985-09-10 | 1989-10-10 | The University Of Michigan | Polyiodinated triglyceride analogs as radiologic agents |
| US4957729A (en) * | 1985-09-10 | 1990-09-18 | The University Of Michigan | Polyiodinated triglyceride analogs as radiologic agents |
| US5093042A (en) * | 1985-09-10 | 1992-03-03 | The University Of Michigan | Polyiodinated triglyceride analogs as radiologic agents |
| US4925649A (en) | 1987-06-12 | 1990-05-15 | The University Of Michigan | Radioiodinated diacylglycerol analogues and methods of use |
| US4965391A (en) * | 1987-10-23 | 1990-10-23 | The University Of Michigan | Radioiodinated phospholipid ether analogues |
| US5347030A (en) * | 1987-10-23 | 1994-09-13 | The Board Of Regents Of The University Of Michigan | Radioiodinated phospholipid ether analogues and methods of using same |
| US5087721A (en) | 1987-10-23 | 1992-02-11 | The University Of Michigan | Radioiodinated phosphate esters |
| US5041859A (en) * | 1988-10-04 | 1991-08-20 | Nikon Corporation | Automatic focusing detection device for cameras |
| US5274113A (en) | 1991-11-01 | 1993-12-28 | Molecular Probes, Inc. | Long wavelength chemically reactive dipyrrometheneboron difluoride dyes and conjugates |
| US5369097A (en) * | 1991-04-25 | 1994-11-29 | The University Of British Columbia | Phosphonates as anti-cancer agents |
| US5783170A (en) * | 1991-11-27 | 1998-07-21 | Diatide, Inc. | Peptide-metal chelate conjugates |
| US5626654A (en) * | 1995-12-05 | 1997-05-06 | Xerox Corporation | Ink compositions containing liposomes |
| WO1998024480A1 (en) | 1996-12-04 | 1998-06-11 | The Regents Of The University Of Michigan | Radioiodinated phospholipid ether analogs and methods of using the same |
| US6255519B1 (en) * | 1996-12-04 | 2001-07-03 | Regents Of The University Of Michigan | Radioiodinated phospholipid ether analogs and methods of using the same |
| US6503478B2 (en) * | 1999-01-13 | 2003-01-07 | Lightouch Medical, Inc. | Chemically specific imaging of tissue |
| AU5799200A (en) * | 1999-06-24 | 2001-01-31 | Academic Hospital At The University Of Amsterdam | Lpl variant therapeutics |
| PT1346041E (pt) * | 2000-11-27 | 2007-06-05 | Praecis Pharm Inc | Agentes terapêuticos e métodos para a sua utilização no tratamento de uma doença amiloidogénica. |
| CN1279907C (zh) * | 2001-06-06 | 2006-10-18 | 布鲁克黑文科学联合会 | 新的金属卟啉化合物及其在放射疗法中用作放射增敏剂的用途 |
| US7220539B1 (en) * | 2002-06-12 | 2007-05-22 | The Salk Institute For Biological Studies | Protein kinase B/Akt modulators and methods for the use thereof |
| US7238786B2 (en) * | 2002-06-14 | 2007-07-03 | Immunomedics, Inc. | Monoclonal antibody cPAM4 |
| AU2003247094A1 (en) * | 2002-07-19 | 2004-02-09 | Ludwig Institute For Cancer Research | Enhancing the effect of radioimmunotherapy in the treatment of tumors |
| WO2005028681A1 (en) | 2003-09-19 | 2005-03-31 | Arcturus Bioscience, Inc. | Predicting breast cancer treatment outcome |
| US7829742B2 (en) | 2003-12-22 | 2010-11-09 | Johns Hopkins University | Boronic acid aryl analogs |
| MXPA06009681A (es) * | 2004-03-02 | 2007-03-15 | Cellectar Llc | Analogos de fosfolipido para el diagnostico y tratamiento del cancer. |
| US7632644B2 (en) * | 2004-03-02 | 2009-12-15 | Cellectar, Inc. | Imaging and selective retention of phospholipid ether analogs |
| US8540968B2 (en) | 2004-03-02 | 2013-09-24 | Cellectar, Inc. | Phospholipid ether analogs as agents for detecting and locating cancer, and methods thereof |
| US7803764B2 (en) * | 2004-03-29 | 2010-09-28 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | Amphipathic glycopeptides |
| CA2572398A1 (en) * | 2004-07-08 | 2006-02-09 | Cellectar, Llc | Virtual colonoscopy with radiolabeled phospholipid ether analogs |
| US20060115426A1 (en) * | 2004-08-11 | 2006-06-01 | Weichert Jamey P | Methods of detecting breast cancer, brain cancer, and pancreatic cancer |
| US7041859B1 (en) | 2004-09-09 | 2006-05-09 | University Of Tennessee Research Foundation | Method for halogenating or radiohalogenating a chemical compound |
| KR20080005178A (ko) * | 2004-12-20 | 2008-01-10 | 셀렉타, 엘엘씨 | 암 검출 및 치료용 인지질 에테르 동족체 |
| US20080075660A1 (en) * | 2006-08-15 | 2008-03-27 | Cellectar, Llc | Near infrared-fluorescence using phospholipid ether analog dyes in endoscopic applications |
| US7893286B2 (en) * | 2007-06-01 | 2011-02-22 | Cellectar, Inc. | Method for the synthesis of phospholipid ethers |
| US8022235B2 (en) * | 2007-06-01 | 2011-09-20 | Cellectar, Inc. | Compositions of phospholipid ether boronic acids and esters and methods for their synthesis and use |
| GB0819280D0 (en) | 2008-10-21 | 2008-11-26 | Gen Electric | Imgaing and radiotherapy methods |
| WO2010144788A2 (en) | 2009-06-12 | 2010-12-16 | Cellectar, Inc. | Ether and alkyl phospholipid compounds for treating cancer and imaging and detection of cancer stem cells |
| WO2011031911A1 (en) * | 2009-09-11 | 2011-03-17 | Cellectar, Inc. | Deuterated alkyl phospholipid compounds, compositions, and methods of use |
| JP2013504590A (ja) * | 2009-09-11 | 2013-02-07 | セレクター，インコーポレイティド | 非放射性リン脂質化合物、組成物、及び使用方法 |
-
2005
- 2005-03-02 MX MXPA06009681A patent/MXPA06009681A/es active IP Right Grant
- 2005-03-02 ES ES08010321.1T patent/ES2440257T3/es active Active
- 2005-03-02 US US10/906,687 patent/US8535641B2/en active Active
- 2005-03-02 EP EP08020805.1A patent/EP2044961B1/en active Active
- 2005-03-02 DE DE602005015687T patent/DE602005015687D1/de active Active
- 2005-03-02 AU AU2005219412A patent/AU2005219412A1/en not_active Abandoned
- 2005-03-02 ES ES08020805T patent/ES2430065T3/es active Active
- 2005-03-02 AT AT05729873T patent/ATE437657T1/de not_active IP Right Cessation
- 2005-03-02 KR KR1020067018488A patent/KR20070015518A/ko not_active Application Discontinuation
- 2005-03-02 JP JP2007501917A patent/JP2007528374A/ja not_active Withdrawn
- 2005-03-02 EP EP08010321.1A patent/EP2044960B1/en active Active
- 2005-03-02 EP EP05729873A patent/EP1729824B1/en active Active
- 2005-03-02 DK DK05729873T patent/DK1729824T3/da active
- 2005-03-02 CA CA002557698A patent/CA2557698A1/en not_active Abandoned
- 2005-03-02 BR BRPI0508425-3A patent/BRPI0508425A/pt not_active Application Discontinuation
- 2005-03-02 WO PCT/US2005/006681 patent/WO2005084716A2/en active Application Filing
- 2005-03-02 CN CN2005800070569A patent/CN1929869B/zh active Active
- 2005-03-02 ES ES05729873T patent/ES2330951T3/es active Active
-
2006
- 2006-08-22 IL IL177645A patent/IL177645A0/en unknown
- 2006-08-23 ZA ZA200607042A patent/ZA200607042B/en unknown
-
2009
- 2009-09-30 HK HK09109089.4A patent/HK1130186A1/xx unknown
-
2012
- 2012-01-13 JP JP2012005213A patent/JP2012097113A/ja not_active Withdrawn
- 2012-10-24 JP JP2012234608A patent/JP2013040201A/ja active Pending
-
2013
- 2013-08-12 US US13/964,315 patent/US8877159B2/en active Active
-
2014
- 2014-07-18 JP JP2014147869A patent/JP6228080B2/ja active Active
- 2014-09-30 US US14/501,373 patent/US9550002B2/en active Active
-
2015
- 2015-01-05 JP JP2015000135A patent/JP6342818B2/ja active Active
-
2016
- 2016-07-08 JP JP2016135920A patent/JP6453818B2/ja active Active
-
2017
- 2017-05-31 JP JP2017108141A patent/JP2017173339A/ja active Pending
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK1729824T3 (da) | Phospholipidanaloger til behandling af cancere | |
| EA200700225A1 (ru) | Аналоги тетрапептида | |
| CY1112277T1 (el) | ΑΝΘΡΩΠΟΠΟΙΗΜΕΝΟΙ ΑΝΤΑΓΩΝΙΣΤΕΣ ΑΝΤΙ-β7 ΚΑΙ ΧΡΗΣΕΙΣ ΑΥΤΩΝ | |
| CR20130455A (es) | Composiciones para el tratamiento de tumores | |
| EA201690265A2 (ru) | Фармацевтические композиции, содержащие замещенные ациланилиды | |
| DK1628685T3 (da) | Antivirale phosphonatanaloge | |
| ECSP034874A (es) | Benzoilsulfonamidas y sulfonilbenzamidinas que se usan como agentes antitumorales | |
| NO20071791L (no) | Preparater og fremgangsmater for diagnostiseringen og behandlingen av tumor | |
| NO20076687L (no) | Oral doseringsform | |
| BRPI0607728A2 (pt) | complexo de lipoproteìna carregado reconstituìdo, composição farmacêutica, e, uso de um complexo de lipoproteìna carregado | |
| SE0301700D0 (sv) | Novel compounds | |
| CR11017A (es) | Anticuerpos anti-robo4 y sus usos | |
| DK1718677T3 (da) | Monovalente antistoffragmenter egnede som terapeutiske midler | |
| CY1111622T1 (el) | Ανθρωποποιημενοι ανταγωνιστες anti-cmet | |
| CR8380A (es) | Metodos para preparar y utilizar compuestos novedosos de celulas madre y sus conjuntos | |
| ATE447551T1 (de) | Biphenyloxyessigsäure - derivate zur behandlung von atemwegserkränkungen | |
| DK1716119T3 (da) | Analoger af benzoquinonholdige ansamyciner til behandling af cancer | |
| EA200700702A1 (ru) | Аналоги локсапина и способы их применения | |
| NO20034661D0 (no) | Nociceptin-analoger | |
| BRPI0509660A (pt) | compostos de beta-carbolina de utilidade no tratamento de doenças inflamatórias | |
| CY2018006I1 (el) | Θεραπευτικο σχημα κλαδριβινης για την θεραπευτικη αντιμετωπιση της σκληρυνσης κατα πλακας | |
| SE0301650D0 (sv) | Novel compounds | |
| DK1492501T3 (da) | Fremgangsmåder med anvendelse af lamellare legemer til terapeutiske formål | |
| CY1108865T1 (el) | Υποκατεστημενες 2,5-διαμινομευθυλο-1η-πυρρολες | |
| DK1687301T3 (da) | Thiaepothilone til behandling af kræftsygdomme |