DK172526B1 - Fremgangsmåde til indvinding af biologisk aktivt bovint og porcint somatotropinprotein fra refraktile legemer i en værtscel - Google Patents

Fremgangsmåde til indvinding af biologisk aktivt bovint og porcint somatotropinprotein fra refraktile legemer i en værtscel Download PDF

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Publication number
DK172526B1
DK172526B1 DK198600809A DK80986A DK172526B1 DK 172526 B1 DK172526 B1 DK 172526B1 DK 198600809 A DK198600809 A DK 198600809A DK 80986 A DK80986 A DK 80986A DK 172526 B1 DK172526 B1 DK 172526B1
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DK
Denmark
Prior art keywords
protein
urea
solution
concentration
somatotropin
Prior art date
Application number
DK198600809A
Other languages
Danish (da)
English (en)
Other versions
DK80986D0 (da
DK80986A (da
Inventor
Larry Andrew Bentle
James William Mitchell
Stephen Bradley Storrs
Grant Tsuyoshi Shimamoto
Original Assignee
Monsanto Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27107301&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK172526(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US06/704,677 external-priority patent/US4652630A/en
Application filed by Monsanto Co filed Critical Monsanto Co
Publication of DK80986D0 publication Critical patent/DK80986D0/da
Publication of DK80986A publication Critical patent/DK80986A/da
Application granted granted Critical
Publication of DK172526B1 publication Critical patent/DK172526B1/da

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • C07K1/1133General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by redox-reactions involving cystein/cystin side chains
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/61Growth hormone [GH], i.e. somatotropin

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Beans For Foods Or Fodder (AREA)
  • Cosmetics (AREA)
  • Dental Preparations (AREA)
DK198600809A 1985-02-22 1986-02-21 Fremgangsmåde til indvinding af biologisk aktivt bovint og porcint somatotropinprotein fra refraktile legemer i en værtscel DK172526B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US70434185A 1985-02-22 1985-02-22
US70467785 1985-02-22
US70434185 1985-02-22
US06/704,677 US4652630A (en) 1985-02-22 1985-02-22 Method of somatotropin naturation

Publications (3)

Publication Number Publication Date
DK80986D0 DK80986D0 (da) 1986-02-21
DK80986A DK80986A (da) 1986-08-23
DK172526B1 true DK172526B1 (da) 1998-11-16

Family

ID=27107301

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198600809A DK172526B1 (da) 1985-02-22 1986-02-21 Fremgangsmåde til indvinding af biologisk aktivt bovint og porcint somatotropinprotein fra refraktile legemer i en værtscel

Country Status (14)

Country Link
EP (1) EP0192629B2 (de)
JP (1) JP2572963B2 (de)
KR (1) KR890003082B1 (de)
CN (1) CN1010097B (de)
AT (1) ATE66930T1 (de)
AU (3) AU587423B2 (de)
CA (1) CA1268300A (de)
DE (1) DE3681185D1 (de)
DK (1) DK172526B1 (de)
ES (1) ES8800957A1 (de)
IE (1) IE58871B1 (de)
IL (1) IL77951A (de)
NZ (1) NZ215259A (de)
SU (1) SU1542402A3 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU612133B2 (en) * 1987-02-20 1991-07-04 Natinco Nv Production of proteins in active forms
JP2669859B2 (ja) * 1987-08-04 1997-10-29 協和醗酵工業株式会社 タンパク質の再活性化法
US4985544A (en) * 1987-08-04 1991-01-15 Kyowa Hakko Kogyo Co., Ltd. Process for renaturing fish growth hormone
JPH01132598A (ja) * 1987-10-14 1989-05-25 Pitman Moore Inc 変性剤溶液中に含まれる組換え蛋白質における分子内ジスルフィド結合の生成を促進する方法
JPH01257491A (ja) * 1988-04-08 1989-10-13 Tosoh Corp 不溶性融合異種蛋白質の処理方法
US5089473A (en) 1988-08-29 1992-02-18 Monsanto Company Somatotropin variants and their use
DE3835350A1 (de) * 1988-10-17 1990-04-19 Boehringer Mannheim Gmbh Aktivierung von gentechnologisch hergestellten, in prokaryonten exprimierten antikoerpern
US5064943A (en) * 1988-12-16 1991-11-12 American Cyanamid Company Method for solubilization and naturation of somatotropin
JP2517100B2 (ja) * 1989-03-08 1996-07-24 協和醗酵工業株式会社 ヒト顆粒球コロニ―刺激因子活性を有する蛋白質の精製法
US5182369A (en) * 1990-02-28 1993-01-26 Monsanto Company Method for purifying somatotropin monomers
US5023323A (en) * 1990-09-12 1991-06-11 Monsanto Company Method of somatotropin naturation
WO1995032222A1 (en) * 1994-05-19 1995-11-30 Monsanto Company Method for purifying somatotropin monomers
AU3109795A (en) * 1994-07-25 1996-02-22 Novartis Ag Process for folding of proteins like recombinant hirudin or epidermal growth factor
ZA9711733B (en) * 1996-12-31 1998-07-01 Monsanto Co Method for solubilization and naturation of somatotropins
WO1999000140A2 (en) * 1997-06-27 1999-01-07 Monsanto Company Accelerating animal hoof growth with somatotropin
US20070021591A1 (en) * 2005-07-25 2007-01-25 Trubion Pharmaceuticals, Inc. Compositions and methods for protein deaggregation
JP4766052B2 (ja) 2005-11-24 2011-09-07 株式会社村田製作所 電気音響変換器
NZ568809A (en) 2005-12-22 2011-08-26 Genentech Inc Recovering and purification of VEGF proteins from prokaryotic cells using polyanionic agents
KR101520105B1 (ko) * 2006-07-14 2015-05-21 제넨테크, 인크. 재조합 단백질의 리폴딩
US11959125B2 (en) 2016-09-15 2024-04-16 Sun Genomics, Inc. Universal method for extracting nucleic acid molecules from a diverse population of one or more types of microbes in a sample
AU2017328927B2 (en) * 2016-09-15 2024-03-07 Sun Genomics Inc. Universal method for extracting nucleic acid molecules from a diverse population of one or more types of microbes in a sample

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59500996A (ja) * 1982-06-07 1984-06-07 セルテク リミテツド キモシンの生産方法
GR79124B (de) * 1982-12-22 1984-10-02 Genentech Inc
DE122080T1 (de) * 1983-03-25 1985-05-23 Celltech Ltd., Slough, Berkshire Verfahren zur herstellung eines proteins.

Also Published As

Publication number Publication date
AU3498089A (en) 1989-09-14
CN1010097B (zh) 1990-10-24
EP0192629A2 (de) 1986-08-27
CA1268300C (en) 1990-04-24
KR890003082B1 (ko) 1989-08-21
DK80986D0 (da) 1986-02-21
AU618386B2 (en) 1991-12-19
JPS61195698A (ja) 1986-08-29
KR860006541A (ko) 1986-09-13
JP2572963B2 (ja) 1997-01-16
CA1268300A (en) 1990-04-24
AU621111B2 (en) 1992-03-05
AU5385386A (en) 1986-08-28
DE3681185D1 (de) 1991-10-10
IL77951A (en) 1990-11-05
DK80986A (da) 1986-08-23
IE58871B1 (en) 1993-11-17
AU3925889A (en) 1990-04-05
ES8800957A1 (es) 1987-12-01
EP0192629B2 (de) 1997-03-05
EP0192629B1 (de) 1991-09-04
NZ215259A (en) 1989-11-28
SU1542402A3 (ru) 1990-02-07
CN86100915A (zh) 1986-08-20
ES552233A0 (es) 1987-12-01
ATE66930T1 (de) 1991-09-15
EP0192629A3 (en) 1988-07-27
AU587423B2 (en) 1989-08-17
IE860466L (en) 1986-08-22

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