AU3109795A - Process for folding of proteins like recombinant hirudin or epidermal growth factor - Google Patents

Process for folding of proteins like recombinant hirudin or epidermal growth factor

Info

Publication number
AU3109795A
AU3109795A AU31097/95A AU3109795A AU3109795A AU 3109795 A AU3109795 A AU 3109795A AU 31097/95 A AU31097/95 A AU 31097/95A AU 3109795 A AU3109795 A AU 3109795A AU 3109795 A AU3109795 A AU 3109795A
Authority
AU
Australia
Prior art keywords
proteins
folding
growth factor
epidermal growth
recombinant hirudin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU31097/95A
Inventor
Jui Yoa Chang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis AG filed Critical Novartis AG
Publication of AU3109795A publication Critical patent/AU3109795A/en
Assigned to NOVARTIS AG reassignment NOVARTIS AG Amend patent request/document other than specification (104) Assignors: CIBA-GEIGY AG
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/485—Epidermal growth factor [EGF] (urogastrone)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • C07K1/1136—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by reversible modification of the secondary, tertiary or quarternary structure, e.g. using denaturating or stabilising agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/815—Protease inhibitors from leeches, e.g. hirudin, eglin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
AU31097/95A 1994-07-25 1995-07-12 Process for folding of proteins like recombinant hirudin or epidermal growth factor Abandoned AU3109795A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP94810437 1994-07-25
EP94810437 1994-07-25
PCT/EP1995/002720 WO1996003425A1 (en) 1994-07-25 1995-07-12 Process for folding of proteins like recombinant hirudin or epidermal growth factor

Publications (1)

Publication Number Publication Date
AU3109795A true AU3109795A (en) 1996-02-22

Family

ID=8218291

Family Applications (1)

Application Number Title Priority Date Filing Date
AU31097/95A Abandoned AU3109795A (en) 1994-07-25 1995-07-12 Process for folding of proteins like recombinant hirudin or epidermal growth factor

Country Status (9)

Country Link
EP (1) EP0804461A1 (en)
JP (1) JPH11505507A (en)
AU (1) AU3109795A (en)
CA (1) CA2194177A1 (en)
FI (1) FI970230A0 (en)
IL (1) IL114699A0 (en)
NO (1) NO970081L (en)
WO (1) WO1996003425A1 (en)
ZA (1) ZA956137B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3734634B2 (en) * 1999-03-03 2006-01-11 ヒゲタ醤油株式会社 Protein activation method and apparatus
US7521479B2 (en) 2001-04-16 2009-04-21 Panacea Pharmaceuticals, Inc. Methods of treating prion disease in mammals
AU2003223936A1 (en) * 2002-05-17 2003-12-02 Kobenhavns Universitet Method for purifying denatured proteins having a desired disulfide bond configuration

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR79124B (en) * 1982-12-22 1984-10-02 Genentech Inc
ES8800957A1 (en) * 1985-02-22 1987-12-01 Monsanto Co Method of somatotropin solubilization and naturation.
GB8927546D0 (en) * 1989-12-06 1990-02-07 Ciba Geigy Process for the production of biologically active tgf-beta
DE69229202T2 (en) * 1991-02-26 2000-01-05 Ajinomoto Kk METHOD FOR PURIFYING HUMAN BCDF
US5290920A (en) * 1992-04-16 1994-03-01 Allelix Biopharmaceuticals Inc. Method of purifying human epidermal growth factor

Also Published As

Publication number Publication date
FI970230A (en) 1997-01-20
JPH11505507A (en) 1999-05-21
CA2194177A1 (en) 1996-02-08
ZA956137B (en) 1996-03-07
IL114699A0 (en) 1995-11-27
NO970081D0 (en) 1997-01-09
EP0804461A1 (en) 1997-11-05
WO1996003425A1 (en) 1996-02-08
FI970230A0 (en) 1997-01-20
NO970081L (en) 1997-01-09

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