DK172463B1 - Anvendelse af oncostatin-A eller derivater deraf til in vitro diagnostisk detektion af tumorceller - Google Patents

Anvendelse af oncostatin-A eller derivater deraf til in vitro diagnostisk detektion af tumorceller Download PDF

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Publication number
DK172463B1
DK172463B1 DK198505406A DK540685A DK172463B1 DK 172463 B1 DK172463 B1 DK 172463B1 DK 198505406 A DK198505406 A DK 198505406A DK 540685 A DK540685 A DK 540685A DK 172463 B1 DK172463 B1 DK 172463B1
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DK
Denmark
Prior art keywords
oncostatin
cells
amino acids
usually
tumor
Prior art date
Application number
DK198505406A
Other languages
Danish (da)
English (en)
Other versions
DK540685D0 (da
DK540685A (da
Inventor
Daniel R Twardzik
Georg J Todaro
Original Assignee
Oncogen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/592,969 external-priority patent/US4590003A/en
Application filed by Oncogen filed Critical Oncogen
Publication of DK540685D0 publication Critical patent/DK540685D0/da
Publication of DK540685A publication Critical patent/DK540685A/da
Application granted granted Critical
Publication of DK172463B1 publication Critical patent/DK172463B1/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/521—Chemokines
    • C07K14/522—Alpha-chemokines, e.g. NAP-2, ENA-78, GRO-alpha/MGSA/NAP-3, GRO-beta/MIP-2alpha, GRO-gamma/MIP-2beta, IP-10, GCP-2, MIG, PBSF, PF-4, KC
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/12—Growth hormone, growth factor other than t-cell or b-cell growth factor, and growth hormone releasing factor; related peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/14—Lymphokine; related peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/26—Containing cys-cys disulfide bridge between nonadjacent cysteine residues

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK198505406A 1984-03-23 1985-11-22 Anvendelse af oncostatin-A eller derivater deraf til in vitro diagnostisk detektion af tumorceller DK172463B1 (da)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US06/592,969 US4590003A (en) 1984-03-23 1984-03-23 Platelet related growth regulator
US59296984 1984-03-23
US06/712,302 US4645828A (en) 1984-03-23 1985-03-15 Platelet related growth regulator
US71230285 1985-03-15
PCT/US1985/000480 WO1985004397A1 (fr) 1984-03-23 1985-03-19 Regulateur de croissance apparente aux thrombocytes
US8500480 1985-03-19

Publications (3)

Publication Number Publication Date
DK540685D0 DK540685D0 (da) 1985-11-22
DK540685A DK540685A (da) 1985-11-22
DK172463B1 true DK172463B1 (da) 1998-08-31

Family

ID=27081584

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198505406A DK172463B1 (da) 1984-03-23 1985-11-22 Anvendelse af oncostatin-A eller derivater deraf til in vitro diagnostisk detektion af tumorceller

Country Status (10)

Country Link
US (1) US4645828A (fr)
EP (1) EP0176588B1 (fr)
JP (2) JPH0242985A (fr)
AT (1) ATE107662T1 (fr)
AU (1) AU587380B2 (fr)
DE (1) DE3587863T2 (fr)
DK (1) DK172463B1 (fr)
FI (1) FI92258C (fr)
HU (1) HU210662B (fr)
WO (1) WO1985004397A1 (fr)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6294172B1 (en) 1983-08-12 2001-09-25 Dade Behring Marburg Gmbh Monoclonal antibodies with specificity for membrane-associated antigens
US5248666A (en) * 1984-03-23 1993-09-28 Oncogen Methods for inhibiting neoplastic cell proliferation using platelet factor 4
EP0487116B1 (fr) * 1984-10-12 1999-12-29 ZymoGenetics, Inc. Analogues biologiquement actifs d'un facteur de croissance provenant de plaquettes sanguines dans des cellules eucaryotiques
US4766073A (en) * 1985-02-25 1988-08-23 Zymogenetics Inc. Expression of biologically active PDGF analogs in eucaryotic cells
US5498600A (en) * 1984-10-12 1996-03-12 Zymogenetics, Inc. Biologically active mosaic proteins
US5187263A (en) * 1984-10-12 1993-02-16 Zymogenetics, Inc. Expression of biologically active PDGE analogs in eucaryotic cells
US4849407A (en) * 1986-08-13 1989-07-18 Zymogenetics, Inc. Biologically active mosaic proteins
US5045633A (en) * 1985-02-25 1991-09-03 Zymogenetics, Inc. Expression of biologically active PDGF analogs in eucaryotic cells
US4844895A (en) * 1985-11-01 1989-07-04 New York University Composition containing a peptide fragment of platelet factor four and method for restoring suppressed immune responses
NZ218634A (en) * 1985-12-20 1991-06-25 Oncogen Peptide identified by its cross reactivity with a cell growth factor, dna, antibodies to peptide and test kits
ATE76311T1 (de) * 1986-08-19 1992-06-15 Genentech Inc Einrichtung und dispersion zum intrapulmonalen eingeben von polypeptidwuchsstoffen und zytokinen.
AU623589B2 (en) * 1987-03-02 1992-05-21 Bristol-Myers Squibb Company Platelet related growth regulator
JPH0739489B2 (ja) * 1987-03-06 1995-05-01 東ソー株式会社 ポリアリ−レンスルフイドの製造方法
US5026639A (en) * 1988-01-14 1991-06-25 Nippon Mining Company, Limited Method to improve mRNA translation and use thereof for production of platelet factor-4
US5800820A (en) * 1989-01-10 1998-09-01 Repligen Corporation Methods and compositions for treatment of angiogenic diseases
US5086164A (en) * 1989-01-10 1992-02-04 Repligen Corporation Novel methods and compositions for treatment of angiogenic diseases
US5187075A (en) * 1989-01-26 1993-02-16 Sri International Cloning and expression of a variant gene of platelet factor 4 and compositions thereof to modulate immune responses
DE3909799A1 (de) 1989-03-24 1990-09-27 Behringwerke Ag Monoklonale antikoerper (mak) gegen tumorassoziierte antigene, ihre herstellung und verwendung
US5112946A (en) * 1989-07-06 1992-05-12 Repligen Corporation Modified pf4 compositions and methods of use
IT1239065B (it) * 1990-05-14 1993-09-20 Fidia Spa Anticorpo monoclonale che inibisce l'azione biologica del fattore piastrinico 4
US5648340A (en) * 1991-10-31 1997-07-15 Barnea; Eytan R. Gestational agents for controlling cell proliferation
JP3159705B2 (ja) * 1990-12-21 2001-04-23 キュラティブ テクノロジーズ，インコーポレーテッド 血管形成ペプチド
US5776892A (en) * 1990-12-21 1998-07-07 Curative Health Services, Inc. Anti-inflammatory peptides
FR2671487B1 (fr) * 1991-01-14 1993-03-19 Oreal Utilisation d'un facteur de croissance dans une composition amincissante.
US5543318A (en) * 1991-06-12 1996-08-06 Smith; David A. Method of isolation, culture and proliferation of human atrial myocytes
CA2106368A1 (fr) * 1992-01-16 1993-07-17 Theodore E. Maione Methodes et compositions pour le traitement de la maladie angiogenique
CA2141602A1 (fr) * 1992-08-26 1994-03-03 Philip Leder Utilisation de la cytokine ip-10 comme agent anti-tumoral
US5304542A (en) * 1992-08-28 1994-04-19 University Of Louisville Research Foundation, Inc. Use of platelet factor 4 to inhibit osteoblast proliferation
CZ195193A3 (en) * 1992-09-25 1994-04-13 Lilly Co Eli Modified factor-4 of blood platelets, process of its preparation and pharmaceutical preparation in which it is comprised
AU7209594A (en) * 1993-06-18 1995-01-17 David F. Counts Anti-inflammatory peptides
US6444421B1 (en) * 1997-11-19 2002-09-03 The United States Of America As Represented By The Department Of Health And Human Services Methods for detecting intermolecular interactions in vivo and in vitro
EP2355847A1 (fr) 2008-10-07 2011-08-17 INSERM (Institut National de la Santé et de la Recherche Médicale) Anticorps neutralisants et fragments de ceux-ci orientés contre un variant 1 de facteur de plaquette 4 (pf4v1)
EP2287183A1 (fr) 2009-07-29 2011-02-23 Institut National De La Sante Et De La Recherche Medicale (Inserm) Mutants PF4 polypeptides exhibiting an increased anti-angiogenic activity
WO2012101125A1 (fr) 2011-01-24 2012-08-02 INSERM (Institut National de la Santé et de la Recherche Médicale) Anticorps spécifiques dirigés contre le cxcl4 humain et leurs utilisations

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL154600B (nl) 1971-02-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen.
US3817837A (en) 1971-05-14 1974-06-18 Syva Corp Enzyme amplification assay
US3766162A (en) 1971-08-24 1973-10-16 Hoffmann La Roche Barbituric acid antigens and antibodies specific therefor
US3996345A (en) 1974-08-12 1976-12-07 Syva Company Fluorescence quenching with immunological pairs in immunoassays
RO80052B (ro) * 1977-11-08 1985-03-30 Genetech Procedeu pentru prepararea unui vehicul recombinat de clonare pentru transformarea unei gazde bacteriene pentru a deveni generator de polipeptida heterologa
US4233402A (en) 1978-04-05 1980-11-11 Syva Company Reagents and method employing channeling
US4479896A (en) * 1981-12-11 1984-10-30 Antoniades Harry N Method for extraction localization and direct recovery of platelet derived growth factor
HUT42101A (en) * 1985-01-07 1987-06-29 Sandoz Ag Process for preparing stomatostatine derivatives and pharmaceutical compositions containing such compounds
NZ218634A (en) * 1985-12-20 1991-06-25 Oncogen Peptide identified by its cross reactivity with a cell growth factor, dna, antibodies to peptide and test kits

Also Published As

Publication number Publication date
FI854604A0 (fi) 1985-11-21
US4645828A (en) 1987-02-24
DK540685D0 (da) 1985-11-22
FI92258B (fi) 1994-06-30
EP0176588A1 (fr) 1986-04-09
AU587380B2 (en) 1989-08-17
DE3587863D1 (de) 1994-07-28
FI92258C (fi) 1994-10-10
AU4235485A (en) 1985-11-01
HUT38300A (en) 1986-05-28
DK540685A (da) 1985-11-22
ATE107662T1 (de) 1994-07-15
FI854604A (fi) 1985-11-21
HU210662B (en) 1995-06-28
DE3587863T2 (de) 1994-10-27
JPH0632631B2 (ja) 1994-05-02
EP0176588A4 (fr) 1989-11-23
WO1985004397A1 (fr) 1985-10-10
JPH0242985A (ja) 1990-02-13
JPH0272896A (ja) 1990-03-13
EP0176588B1 (fr) 1994-06-22

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed