DK172221B1 - Anvendelse af ACE-inhibitorer eller deres fysiologisk acceptable salte til fremstilling af lægemidler med nootrop virkning - Google Patents

Anvendelse af ACE-inhibitorer eller deres fysiologisk acceptable salte til fremstilling af lægemidler med nootrop virkning Download PDF

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Publication number
DK172221B1
DK172221B1 DK153587A DK153587A DK172221B1 DK 172221 B1 DK172221 B1 DK 172221B1 DK 153587 A DK153587 A DK 153587A DK 153587 A DK153587 A DK 153587A DK 172221 B1 DK172221 B1 DK 172221B1
Authority
DK
Denmark
Prior art keywords
carboxylic acid
alanyl
carbethoxy
pyrrolidine
octane
Prior art date
Application number
DK153587A
Other languages
Danish (da)
English (en)
Other versions
DK153587A (da
DK153587D0 (da
Inventor
Franz Hock
Josef Scholtholt
Hansjoerg Urbach
Rainer Henning
Ulrich Lerch
Wolf-Ulrich Nickel
Wolfgang Rueger
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of DK153587D0 publication Critical patent/DK153587D0/da
Publication of DK153587A publication Critical patent/DK153587A/da
Application granted granted Critical
Publication of DK172221B1 publication Critical patent/DK172221B1/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
DK153587A 1986-03-27 1987-03-26 Anvendelse af ACE-inhibitorer eller deres fysiologisk acceptable salte til fremstilling af lægemidler med nootrop virkning DK172221B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19863610391 DE3610391A1 (de) 1986-03-27 1986-03-27 Verbindungen mit nootroper wirkung, diese enthaltende mittel und deren verwendung bei der behandlung und prophylaxe cognitiver dysfunktionen
DE3610391 1986-03-27

Publications (3)

Publication Number Publication Date
DK153587D0 DK153587D0 (da) 1987-03-26
DK153587A DK153587A (da) 1987-09-28
DK172221B1 true DK172221B1 (da) 1998-01-12

Family

ID=6297417

Family Applications (1)

Application Number Title Priority Date Filing Date
DK153587A DK172221B1 (da) 1986-03-27 1987-03-26 Anvendelse af ACE-inhibitorer eller deres fysiologisk acceptable salte til fremstilling af lægemidler med nootrop virkning

Country Status (25)

Country Link
EP (1) EP0243645B1 (cs)
JP (1) JPS62240698A (cs)
KR (1) KR870008841A (cs)
CN (1) CN1031267C (cs)
AT (1) ATE102954T1 (cs)
AU (1) AU621278B2 (cs)
CA (1) CA1341064C (cs)
CS (2) CS212687A3 (cs)
DD (1) DD280765A5 (cs)
DE (2) DE3610391A1 (cs)
DK (1) DK172221B1 (cs)
EG (1) EG18175A (cs)
ES (1) ES2061447T3 (cs)
FI (1) FI91876C (cs)
HU (2) HU202118B (cs)
IE (1) IE62456B1 (cs)
MA (1) MA20919A1 (cs)
NO (1) NO178546C (cs)
NZ (1) NZ219764A (cs)
OA (1) OA08506A (cs)
PH (1) PH27210A (cs)
PT (1) PT84564B (cs)
RU (1) RU1836335C (cs)
TN (1) TNSN87045A1 (cs)
ZA (1) ZA872230B (cs)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5231084A (en) * 1986-03-27 1993-07-27 Hoechst Aktiengesellschaft Compounds having a cognition adjuvant action, agents containing them, and the use thereof for the treatment and prophylaxis of cognitive dysfuncitons
US4743450A (en) * 1987-02-24 1988-05-10 Warner-Lambert Company Stabilized compositions
AU612137B2 (en) * 1987-04-27 1991-07-04 E.R. Squibb & Sons, Inc. Method for inhibiting loss of cognitive functions employing an ace inhibitor
DE3731085A1 (de) * 1987-09-16 1989-04-06 Hoechst Ag Neue aminosaeureester, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung
DE3739690A1 (de) * 1987-11-24 1989-06-08 Hoechst Ag Stabilisierte arzneistoffe, verfahren zu ihrer herstellung sowie stabile arzneizubereitungen
DE3801587A1 (de) * 1988-01-21 1989-08-03 Hoechst Ag Neue aminosaeureglyceride, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung
EP0331609A3 (de) * 1988-01-27 1992-07-01 Hoechst Aktiengesellschaft Angiotensin-Converting-Enzym-Hemmstoffe mit psychotroper Wirkung
DE3803225A1 (de) * 1988-02-04 1989-08-17 Hoechst Ag Aminosaeureamide mit psychotroper wirkung, verfahren zu ihrer herstellung, sie enthaltende mittel und deren verwendung
JPH01275529A (ja) * 1988-03-21 1989-11-06 E R Squibb & Sons Inc 晩発性運動障害の抑制治療剤
US5037821A (en) * 1988-06-01 1991-08-06 E. R. Squibb & Sons, Inc. Method for inhibiting loss of cognitive functions employing a calcium channel blocker alone or in combination with an ACE inhibitor
US5093129A (en) * 1989-01-30 1992-03-03 E. R. Squibb & Sons, Inc. Method for treating addiction to a drug of abuse employing an ace inhibitor
US5032578A (en) * 1990-09-17 1991-07-16 E. R. Squibb & Sons, Inc. Method for preventing or treating depression employing a combination of an ace inhibitor and a drug that acts at serotonin receptors
AU2002245692A1 (en) * 2001-03-15 2002-10-03 David Pharmaceuticals Methods for restoring cognitive function following systemic stress

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0050800B2 (en) * 1980-10-23 1995-06-07 Schering Corporation Carboxyalkyl dipeptides, processes for their production and pharmaceutical compositions containing them
DE3300774A1 (de) * 1983-01-12 1984-07-12 Hoechst Ag, 6230 Frankfurt Neue spirocyclische aminosaeuren, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie neue spirocyclische aminosaeuren als zwischenprodukte und verfahren zu deren herstellung

Also Published As

Publication number Publication date
FI871304A0 (fi) 1987-03-25
DE3610391A1 (de) 1987-10-08
EP0243645A3 (en) 1990-01-24
KR870008841A (ko) 1987-10-21
CS276179B6 (en) 1992-04-15
CN87102304A (zh) 1987-12-30
FI871304A (fi) 1987-09-28
EP0243645A2 (de) 1987-11-04
IE870784L (en) 1987-09-27
ES2061447T3 (es) 1994-12-16
PT84564B (pt) 1989-11-10
TNSN87045A1 (fr) 1990-01-01
NZ219764A (en) 1990-11-27
DE3789330D1 (de) 1994-04-21
CN1031267C (zh) 1996-03-13
EP0243645B1 (de) 1994-03-16
HU203117B (en) 1991-05-28
FI91876B (fi) 1994-05-13
NO178546C (no) 1996-04-17
AU7064987A (en) 1987-10-01
CS276385B6 (en) 1992-05-13
ATE102954T1 (de) 1994-04-15
PT84564A (de) 1987-04-01
CS651989A3 (en) 1992-05-13
DK153587A (da) 1987-09-28
DD280765A5 (de) 1990-07-18
NO871282D0 (no) 1987-03-26
OA08506A (fr) 1988-07-29
HU202118B (en) 1991-02-28
HUT46046A (en) 1988-09-28
NO871282L (no) 1987-09-28
DK153587D0 (da) 1987-03-26
EG18175A (en) 1994-07-30
HU896609D0 (en) 1990-02-28
FI91876C (fi) 1994-08-25
ZA872230B (en) 1987-09-21
PH27210A (en) 1993-05-04
CA1341064C (en) 2000-08-01
AU621278B2 (en) 1992-03-12
IE62456B1 (en) 1995-02-08
CS212687A3 (en) 1992-04-15
MA20919A1 (fr) 1987-10-01
NO178546B (no) 1996-01-08
JPS62240698A (ja) 1987-10-21
RU1836335C (ru) 1993-08-23

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PUP Patent expired