AU7064987A - Compounds having a cognition adjuvant action, agents containing them, and the use thereof for the treatment and prophylaxis of cognitive dysfunctions - Google Patents

Compounds having a cognition adjuvant action, agents containing them, and the use thereof for the treatment and prophylaxis of cognitive dysfunctions

Info

Publication number
AU7064987A
AU7064987A AU70649/87A AU7064987A AU7064987A AU 7064987 A AU7064987 A AU 7064987A AU 70649/87 A AU70649/87 A AU 70649/87A AU 7064987 A AU7064987 A AU 7064987A AU 7064987 A AU7064987 A AU 7064987A
Authority
AU
Australia
Prior art keywords
prophylaxis
treatment
compounds
agents containing
cognitive dysfunctions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU70649/87A
Other versions
AU621278B2 (en
Inventor
Rainer Henning
Franz Hock
Ulrich Lerch
Wolf-Ulrich Nickel
Wolfgang Ruger
Josef Scholtholt
Hansjorg Urbach
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis Deutschland GmbH
Original Assignee
Sanofi Aventis Deutschland GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland GmbH filed Critical Sanofi Aventis Deutschland GmbH
Publication of AU7064987A publication Critical patent/AU7064987A/en
Application granted granted Critical
Publication of AU621278B2 publication Critical patent/AU621278B2/en
Assigned to AVENTIS PHARMA DEUTSCHLAND GMBH reassignment AVENTIS PHARMA DEUTSCHLAND GMBH Alteration of Name(s) in Register under S187 Assignors: HOECHST AKTIENGESELLSCHAFT
Assigned to SANOFI-AVENTIS DEUTSCHLAND GMBH reassignment SANOFI-AVENTIS DEUTSCHLAND GMBH Request to Amend Deed and Register Assignors: AVENTIS PHARMA DEUTSCHLAND GMBH
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

The invention relates to novel compounds having a nootropic activity, the use of ACE inhibitors as medicaments having nootropic activity, agents containing them, and their use in the treatment and prophylaxis of cognitive malfunctions.
AU70649/87A 1986-03-27 1987-03-26 Compounds having a cognition adjuvant action, agents containing them, and the use thereof for the treatment and prophylaxis of cognitive dysfunctions Expired AU621278B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19863610391 DE3610391A1 (en) 1986-03-27 1986-03-27 COMPOUNDS WITH NOOTROPPER ACTION, THESE CONTAINERS AND THEIR USE IN THE TREATMENT AND PROPHYLAXIS OF COGNITIVE DYSFUNCTIONS
DE3610391 1986-03-27

Publications (2)

Publication Number Publication Date
AU7064987A true AU7064987A (en) 1987-10-01
AU621278B2 AU621278B2 (en) 1992-03-12

Family

ID=6297417

Family Applications (1)

Application Number Title Priority Date Filing Date
AU70649/87A Expired AU621278B2 (en) 1986-03-27 1987-03-26 Compounds having a cognition adjuvant action, agents containing them, and the use thereof for the treatment and prophylaxis of cognitive dysfunctions

Country Status (25)

Country Link
EP (1) EP0243645B1 (en)
JP (1) JPS62240698A (en)
KR (1) KR870008841A (en)
CN (1) CN1031267C (en)
AT (1) ATE102954T1 (en)
AU (1) AU621278B2 (en)
CA (1) CA1341064C (en)
CS (2) CS212687A3 (en)
DD (1) DD280765A5 (en)
DE (2) DE3610391A1 (en)
DK (1) DK172221B1 (en)
EG (1) EG18175A (en)
ES (1) ES2061447T3 (en)
FI (1) FI91876C (en)
HU (2) HU203117B (en)
IE (1) IE62456B1 (en)
MA (1) MA20919A1 (en)
NO (1) NO178546C (en)
NZ (1) NZ219764A (en)
OA (1) OA08506A (en)
PH (1) PH27210A (en)
PT (1) PT84564B (en)
RU (1) RU1836335C (en)
TN (1) TNSN87045A1 (en)
ZA (1) ZA872230B (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU615495B2 (en) * 1987-11-24 1991-10-03 Sanofi-Aventis Deutschland Gmbh Stabilized medicinal substances, a process for the preparation thereof, and stable medicinal formulations
AU617118B2 (en) * 1987-09-16 1991-11-21 Hoechst Aktiengesellschaft New amino acid esters, a process for their preparation, medicaments containing them, and the use thereof

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5231084A (en) * 1986-03-27 1993-07-27 Hoechst Aktiengesellschaft Compounds having a cognition adjuvant action, agents containing them, and the use thereof for the treatment and prophylaxis of cognitive dysfuncitons
US4743450A (en) * 1987-02-24 1988-05-10 Warner-Lambert Company Stabilized compositions
CA1321753C (en) * 1987-04-27 1993-08-31 Abraham Sudilovsky Method for inhibiting loss of cognitive functions employing an ace inhibitor
DE3801587A1 (en) * 1988-01-21 1989-08-03 Hoechst Ag NEW AMINO ACID GLYCERIDES, METHOD FOR THE PRODUCTION THEREOF, MEDICINAL PRODUCTS CONTAINING THEM AND THE USE THEREOF
EP0331609A3 (en) * 1988-01-27 1992-07-01 Hoechst Aktiengesellschaft Angiotensin converting enzyme inhibitors having psychotropic effects
DE3803225A1 (en) * 1988-02-04 1989-08-17 Hoechst Ag AMINO ACID AMIDE WITH PSYCHOTROPIC EFFECT, METHOD FOR THE PRODUCTION THEREOF, AGENTS CONTAINING THE SAME AND THEIR USE
JPH01275529A (en) * 1988-03-21 1989-11-06 E R Squibb & Sons Inc Suppressing treatment agent of delayed motion effect
US5037821A (en) * 1988-06-01 1991-08-06 E. R. Squibb & Sons, Inc. Method for inhibiting loss of cognitive functions employing a calcium channel blocker alone or in combination with an ACE inhibitor
US5093129A (en) * 1989-01-30 1992-03-03 E. R. Squibb & Sons, Inc. Method for treating addiction to a drug of abuse employing an ace inhibitor
US5032578A (en) * 1990-09-17 1991-07-16 E. R. Squibb & Sons, Inc. Method for preventing or treating depression employing a combination of an ace inhibitor and a drug that acts at serotonin receptors
WO2002074293A2 (en) * 2001-03-15 2002-09-26 Saegis Pharmaceuticals Inc Methods for restoring cognitive function following systemic stress

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19575012I2 (en) * 1980-10-23 2002-01-24 Schering Corp Carboxyalkyl dipeptides Process for their preparation and medicaments containing them
DE3300774A1 (en) * 1983-01-12 1984-07-12 Hoechst Ag, 6230 Frankfurt NEW SPIROCYCLIC AMINO ACIDS, METHOD FOR THE PRODUCTION THEREOF AND THE USE THEREOF AND NEW SPIROCYCLIC AMINO ACIDS AS INTERMEDIATE PRODUCTS AND METHOD FOR THE PRODUCTION THEREOF

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU617118B2 (en) * 1987-09-16 1991-11-21 Hoechst Aktiengesellschaft New amino acid esters, a process for their preparation, medicaments containing them, and the use thereof
AU615495B2 (en) * 1987-11-24 1991-10-03 Sanofi-Aventis Deutschland Gmbh Stabilized medicinal substances, a process for the preparation thereof, and stable medicinal formulations

Also Published As

Publication number Publication date
CS276179B6 (en) 1992-04-15
NO871282L (en) 1987-09-28
OA08506A (en) 1988-07-29
FI871304A0 (en) 1987-03-25
DE3610391A1 (en) 1987-10-08
JPS62240698A (en) 1987-10-21
PH27210A (en) 1993-05-04
EP0243645A3 (en) 1990-01-24
IE870784L (en) 1987-09-27
CN1031267C (en) 1996-03-13
ATE102954T1 (en) 1994-04-15
NO871282D0 (en) 1987-03-26
NO178546B (en) 1996-01-08
CS212687A3 (en) 1992-04-15
DK153587D0 (en) 1987-03-26
EP0243645A2 (en) 1987-11-04
PT84564A (en) 1987-04-01
MA20919A1 (en) 1987-10-01
CN87102304A (en) 1987-12-30
ZA872230B (en) 1987-09-21
RU1836335C (en) 1993-08-23
KR870008841A (en) 1987-10-21
AU621278B2 (en) 1992-03-12
DD280765A5 (en) 1990-07-18
HU203117B (en) 1991-05-28
FI91876B (en) 1994-05-13
CS276385B6 (en) 1992-05-13
NO178546C (en) 1996-04-17
HU202118B (en) 1991-02-28
FI871304A (en) 1987-09-28
EP0243645B1 (en) 1994-03-16
DK153587A (en) 1987-09-28
IE62456B1 (en) 1995-02-08
CA1341064C (en) 2000-08-01
PT84564B (en) 1989-11-10
ES2061447T3 (en) 1994-12-16
DE3789330D1 (en) 1994-04-21
FI91876C (en) 1994-08-25
NZ219764A (en) 1990-11-27
HUT46046A (en) 1988-09-28
CS651989A3 (en) 1992-05-13
DK172221B1 (en) 1998-01-12
HU896609D0 (en) 1990-02-28
EG18175A (en) 1994-07-30
TNSN87045A1 (en) 1990-01-01

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Legal Events

Date Code Title Description
PC Assignment registered

Owner name: AVENTIS PHARMA DEUTSCHLAND GMBH

Free format text: FORMER OWNER WAS: HOECHST AKTIENGESELLSCHAFT