CS651989A3 - Process for preparing compounds with nootropic effect - Google Patents

Process for preparing compounds with nootropic effect

Info

Publication number
CS651989A3
CS651989A3 CS896519A CS651989A CS651989A3 CS 651989 A3 CS651989 A3 CS 651989A3 CS 896519 A CS896519 A CS 896519A CS 651989 A CS651989 A CS 651989A CS 651989 A3 CS651989 A3 CS 651989A3
Authority
CS
Czechoslovakia
Prior art keywords
preparing compounds
nootropic effect
nootropic
effect
nootropic activity
Prior art date
Application number
CS896519A
Other languages
English (en)
Other versions
CS276385B6 (en
Inventor
Franz Dr Hock
Josef Prof Dr Scholtholt
Hansjorg Dr Urbach
Rainer Dr Henning
Ulrich Dr Lerch
Wolf-Ulrich Dr Nickel
Wolfgang Dr Ruger
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of CS276385B6 publication Critical patent/CS276385B6/cs
Publication of CS651989A3 publication Critical patent/CS651989A3/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Cardiology (AREA)
  • Psychiatry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Epoxy Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Indole Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
CS896519A 1986-03-27 1987-03-27 Process for preparing compounds with nootropic effect CS651989A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19863610391 DE3610391A1 (de) 1986-03-27 1986-03-27 Verbindungen mit nootroper wirkung, diese enthaltende mittel und deren verwendung bei der behandlung und prophylaxe cognitiver dysfunktionen

Publications (2)

Publication Number Publication Date
CS276385B6 CS276385B6 (en) 1992-05-13
CS651989A3 true CS651989A3 (en) 1992-05-13

Family

ID=6297417

Family Applications (2)

Application Number Title Priority Date Filing Date
CS872126A CS212687A3 (en) 1986-03-27 1987-03-27 Process for preparing compounds with nootropic activity
CS896519A CS651989A3 (en) 1986-03-27 1987-03-27 Process for preparing compounds with nootropic effect

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CS872126A CS212687A3 (en) 1986-03-27 1987-03-27 Process for preparing compounds with nootropic activity

Country Status (25)

Country Link
EP (1) EP0243645B1 (cs)
JP (1) JPS62240698A (cs)
KR (1) KR870008841A (cs)
CN (1) CN1031267C (cs)
AT (1) ATE102954T1 (cs)
AU (1) AU621278B2 (cs)
CA (1) CA1341064C (cs)
CS (2) CS212687A3 (cs)
DD (1) DD280765A5 (cs)
DE (2) DE3610391A1 (cs)
DK (1) DK172221B1 (cs)
EG (1) EG18175A (cs)
ES (1) ES2061447T3 (cs)
FI (1) FI91876C (cs)
HU (2) HU202118B (cs)
IE (1) IE62456B1 (cs)
MA (1) MA20919A1 (cs)
NO (1) NO178546C (cs)
NZ (1) NZ219764A (cs)
OA (1) OA08506A (cs)
PH (1) PH27210A (cs)
PT (1) PT84564B (cs)
RU (1) RU1836335C (cs)
TN (1) TNSN87045A1 (cs)
ZA (1) ZA872230B (cs)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5231084A (en) * 1986-03-27 1993-07-27 Hoechst Aktiengesellschaft Compounds having a cognition adjuvant action, agents containing them, and the use thereof for the treatment and prophylaxis of cognitive dysfuncitons
US4743450A (en) * 1987-02-24 1988-05-10 Warner-Lambert Company Stabilized compositions
AU612137B2 (en) * 1987-04-27 1991-07-04 E.R. Squibb & Sons, Inc. Method for inhibiting loss of cognitive functions employing an ace inhibitor
DE3731085A1 (de) * 1987-09-16 1989-04-06 Hoechst Ag Neue aminosaeureester, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung
DE3739690A1 (de) * 1987-11-24 1989-06-08 Hoechst Ag Stabilisierte arzneistoffe, verfahren zu ihrer herstellung sowie stabile arzneizubereitungen
DE3801587A1 (de) * 1988-01-21 1989-08-03 Hoechst Ag Neue aminosaeureglyceride, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung
EP0331609A3 (de) * 1988-01-27 1992-07-01 Hoechst Aktiengesellschaft Angiotensin-Converting-Enzym-Hemmstoffe mit psychotroper Wirkung
DE3803225A1 (de) * 1988-02-04 1989-08-17 Hoechst Ag Aminosaeureamide mit psychotroper wirkung, verfahren zu ihrer herstellung, sie enthaltende mittel und deren verwendung
JPH01275529A (ja) * 1988-03-21 1989-11-06 E R Squibb & Sons Inc 晩発性運動障害の抑制治療剤
US5037821A (en) * 1988-06-01 1991-08-06 E. R. Squibb & Sons, Inc. Method for inhibiting loss of cognitive functions employing a calcium channel blocker alone or in combination with an ACE inhibitor
US5093129A (en) * 1989-01-30 1992-03-03 E. R. Squibb & Sons, Inc. Method for treating addiction to a drug of abuse employing an ace inhibitor
US5032578A (en) * 1990-09-17 1991-07-16 E. R. Squibb & Sons, Inc. Method for preventing or treating depression employing a combination of an ace inhibitor and a drug that acts at serotonin receptors
EP1372620A2 (en) * 2001-03-15 2004-01-02 Saegis Pharmaceuticals Methods for restoring cognitive function following systemic stress

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3174844D1 (en) * 1980-10-23 1986-07-24 Schering Corp Carboxyalkyl dipeptides, processes for their production and pharmaceutical compositions containing them
DE3300774A1 (de) * 1983-01-12 1984-07-12 Hoechst Ag, 6230 Frankfurt Neue spirocyclische aminosaeuren, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie neue spirocyclische aminosaeuren als zwischenprodukte und verfahren zu deren herstellung

Also Published As

Publication number Publication date
MA20919A1 (fr) 1987-10-01
NO871282D0 (no) 1987-03-26
CN87102304A (zh) 1987-12-30
CS276179B6 (en) 1992-04-15
OA08506A (fr) 1988-07-29
IE62456B1 (en) 1995-02-08
CS276385B6 (en) 1992-05-13
RU1836335C (ru) 1993-08-23
FI91876B (fi) 1994-05-13
ZA872230B (en) 1987-09-21
HU203117B (en) 1991-05-28
ES2061447T3 (es) 1994-12-16
TNSN87045A1 (fr) 1990-01-01
DK153587A (da) 1987-09-28
CN1031267C (zh) 1996-03-13
EP0243645A3 (en) 1990-01-24
DE3789330D1 (de) 1994-04-21
ATE102954T1 (de) 1994-04-15
DK153587D0 (da) 1987-03-26
PH27210A (en) 1993-05-04
FI871304A (fi) 1987-09-28
NO178546B (no) 1996-01-08
HUT46046A (en) 1988-09-28
JPS62240698A (ja) 1987-10-21
PT84564A (de) 1987-04-01
EP0243645A2 (de) 1987-11-04
CA1341064C (en) 2000-08-01
EP0243645B1 (de) 1994-03-16
DK172221B1 (da) 1998-01-12
HU202118B (en) 1991-02-28
HU896609D0 (en) 1990-02-28
AU7064987A (en) 1987-10-01
NZ219764A (en) 1990-11-27
EG18175A (en) 1994-07-30
DD280765A5 (de) 1990-07-18
KR870008841A (ko) 1987-10-21
PT84564B (pt) 1989-11-10
FI871304A0 (fi) 1987-03-25
DE3610391A1 (de) 1987-10-08
CS212687A3 (en) 1992-04-15
AU621278B2 (en) 1992-03-12
NO871282L (no) 1987-09-28
FI91876C (fi) 1994-08-25
NO178546C (no) 1996-04-17
IE870784L (en) 1987-09-27

Similar Documents

Publication Publication Date Title
HUT43582A (en) Process for production of derivatives of 4,5,6-substituated-n-/substituated phenil/-piramidin-amin and medical compounds containing thereof
GR860571B (en) Labdan-derivatives process for their preparation and their use as medicaments
CS651989A3 (en) Process for preparing compounds with nootropic effect
IL89031A0 (en) Medicaments containing a benzamide for the treatment or prevention of cognitive disorders and their preparation
ES8503643A1 (es) Un procedimiento para la preparacion de compuestos de bis (carboxamida)
ZA886459B (en) Use of bezafibrate for treating diabetes
HUT46837A (en) Compositions of insectifuge and acarifuge activity containing alpha, omega-amino-alkohol derivatives as active components and process for producing the active components
ES8203086A1 (es) Un procedimiento para la produccion de n,n'-bis-(3-picolil) -4-metoxi-isoftalamida monohidratada
GR3002365T3 (en) Medicines containing as a mixture interferon and 1-desoxy-piperidinoses, process for their manufacture and their use
EP0257631A3 (en) Oxolabdanes, a process for their preparation and their use as medicaments
ZA872677B (en) Pharmaceutical compositions for the treatment of intermittent claudication
ES2001577A6 (es) Un procedimiento para preparar compuestos relacionados con espergualina
JO1516B1 (en) Compounds with cognitive effectiveness, factors containing them, and their use in treatment and disease prevention for cognitive dysfunction
HUT41441A (en) Process for producing antracyclin derivatives and pharmaceutical compositions containing themas active agents
ZA869624B (en) Derivatives of 1-benzene sulphonyl 2-oxo-5-alkoxy pyrrolidine,their preparation process,their use as medicaments and the compositions containing them

Legal Events

Date Code Title Description
IF00 In force as of 2000-06-30 in czech republic
MK4A Patent expired

Effective date: 20070327